Septerna (SEPN) director Bernard Coulie receives 15,000 stock options

Rhea-AI Filing Summary

Septerna, Inc. director Bernard Coulie received a grant of stock options covering 15,000 shares of common stock. The options have an exercise price of $37.34 per share and expire on June 25, 2036. All 15,000 options vest in full on the earlier of June 26, 2027 or the date of Septerna’s next annual stockholders’ meeting, as long as he continues serving the company through that date. This is a compensation-related award, not an open-market share purchase or sale.

Insider Trade Summary

1 transaction reported

Mixed 1 txn

Insider Coulie Bernard

Role null

Type	Security	Shares	Price	Value
Grant/Award	Stock Option (Right to Buy)	15,000	$0.00	--

Holdings After Transaction: Stock Option (Right to Buy) — 15,000 shares (Direct, null)

Footnotes (1)

1. [object Object]

Key Figures

Option grant size: 15,000 options Exercise price: $37.34 per share Total options after grant: 15,000 options +2 more

5 metrics

Option grant size 15,000 options Stock Option (Right to Buy) grant on June 26, 2026

Exercise price $37.34 per share Exercise price for 15,000 stock options

Total options after grant 15,000 options Total derivative securities following this transaction

Expiration date June 25, 2036 Option expiration for 15,000 stock options

Vesting date trigger June 26, 2027 or next annual meeting Full vesting contingent on continued service

Key Terms

Stock Option (Right to Buy), exercise price, vest in full, annual meeting of stockholders, +1 more

5 terms

Stock Option (Right to Buy) financial

"security_title: Stock Option (Right to Buy)"

exercise price financial

"conversion_or_exercise_price: 37.3400"

The exercise price is the fixed amount at which you can buy or sell an asset, like a stock, when using an options contract. It matters because it helps determine whether exercising the option will be profitable or not, depending on the current market price. Think of it as the set price you agree on today to buy or sell later.

vest in full financial

"The shares underlying the stock option vest in full upon the earlier"

annual meeting of stockholders financial

"the date of the Issuer's next annual meeting of stockholders"

expiration date financial

"expiration_date: 2036-06-25T00:00:00.000Z"

The expiration date is the deadline after which a financial contract, such as an option or a futures agreement, is no longer valid or can be exercised. It matters to investors because it determines the timeframe during which they can take action or benefit from the contract, similar to how a coupon or a food item has a limited period of usefulness. Once the expiration date passes, the contract loses its value or ability to be used.

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Form 4 Insider Transactions: What Each Field Means →

Available on EDGAR 06/30/2026 - 07:00 PM Accepted by SEC EDGAR 06/30/2026 - 07:00 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Coulie Bernard

(Last) (First) (Middle)

C/O SEPTERNA, INC.

250 EAST GRAND AVENUE

(Street)

SOUTH SAN FRANCISCO CALIFORNIA 94080

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Septerna, Inc. [ SEPN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
06/26/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$37.34	06/26/2026		A		15,000		(1)	06/25/2036	Common Stock	15,000	$0	15,000	D

Explanation of Responses:

1. The shares underlying the stock option vest in full upon the earlier of (i) June 26, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer through such vesting date.

Remarks:

Exhibit 24.2 - Substitute Power of Attorney

	/s/ Mark A. Wilson, Attorney-in-Fact	06/30/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What did Septerna (SEPN) director Bernard Coulie report in this Form 4?

Bernard Coulie reported receiving a grant of stock options for 15,000 shares of Septerna common stock. These options were awarded as compensation and give him the right to buy shares at a fixed exercise price if and when they vest in the future.

How many Septerna (SEPN) stock options did Bernard Coulie receive and at what price?

He received stock options covering 15,000 shares of Septerna common stock with an exercise price of $37.34 per share. This means he can buy up to 15,000 shares at $37.34 each once the options have vested and before they expire.

When do Bernard Coulie’s Septerna (SEPN) stock options vest?

The options vest in full on the earlier of June 26, 2027 or the date of Septerna’s next annual meeting of stockholders. Vesting is contingent on Bernard Coulie continuing to serve the company through whichever of these dates occurs first.

When do the newly granted Septerna (SEPN) stock options expire?

These stock options expire on June 25, 2036. After that expiration date, Bernard Coulie will no longer be able to exercise the options to purchase Septerna common shares, even if they have vested and were not previously exercised.

Is this Septerna (SEPN) Form 4 an open-market stock purchase or sale?

No, this Form 4 reflects a compensation-related grant of stock options, not an open-market trade. Bernard Coulie did not buy or sell shares in the market; he received options giving him the future right to purchase shares at a fixed price.