Shuttle Pharmaceuticals Holdings (SHPH) holder HRT Financial sells 83,149 shares

Rhea-AI Filing Summary

HRT Financial LP, a ten percent owner of Shuttle Pharmaceuticals Holdings, Inc., reported open-market sales of a total of 83,149 shares of Common Stock. The sales on July 13–14, 2026 were executed at $4.67 and $4.48 per share, leaving no directly held shares of this security after the transactions.

Insider Trade Summary

Net Seller: 83,149 shares ($372,704)

Net Sell 2 txns

Insider HRT FINANCIAL LP

Role 10% Owner

Sold 83,149 shs ($373K)

Type	Security	Shares	Price	Value
Sale	Common Stock	82,116	$4.48	$368K
Sale	Common Stock	1,033	$4.67	$5K

Holdings After Transaction: Common Stock — 0 shares (Direct)

Footnotes (1)

Key Figures

Shares sold on July 13, 2026: 1,033 shares Shares sold on July 14, 2026: 82,116 shares Total shares sold: 83,149 shares +3 more

6 metrics

Shares sold on July 13, 2026 1,033 shares Open-market sale of Common Stock at $4.67 per share

Shares sold on July 14, 2026 82,116 shares Open-market sale of Common Stock at $4.48 per share

Total shares sold 83,149 shares Aggregate Common Stock sold by HRT Financial LP across both transactions

Sale price on July 13, 2026 $4.67 per share Price for 1,033-share open-market sale of Common Stock

Sale price on July 14, 2026 $4.48 per share Price for 82,116-share open-market sale of Common Stock

Shares held after final transaction 0 shares Directly held Common Stock position after July 14, 2026 sale

Key Terms

open-market sale, ten percent owner, non-derivative

3 terms

open-market sale financial

"reported an open-market sale of Common Stock on July 14, 2026"

An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.

ten percent owner financial

"HRT Financial LP is indicated as a ten percent owner of the issuer"

non-derivative financial

"Each transaction is classified as a non-derivative Common Stock transaction"

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Form 4 Insider Transactions: What Each Field Means →

Available on EDGAR 07/15/2026 - 03:36 PM Accepted by SEC EDGAR 07/15/2026 - 03:36 PM Learn about SEC filing dates

FAQ

What insider transactions did HRT Financial LP report for SHPH?

HRT Financial LP, a ten percent owner of Shuttle Pharmaceuticals Holdings, Inc. (SHPH), reported two open-market sales of Common Stock. It sold 1,033 shares at $4.67 on July 13, 2026 and 82,116 shares at $4.48 on July 14, 2026.

How many Shuttle Pharmaceuticals (SHPH) shares did HRT Financial LP sell?

Across two transactions, HRT Financial LP sold a total of 83,149 shares of Shuttle Pharmaceuticals Holdings, Inc. (SHPH) Common Stock. The reported sales were 1,033 shares on July 13, 2026 and 82,116 shares on July 14, 2026.

At what prices did HRT Financial LP sell SHPH shares?

HRT Financial LP’s reported sales of Shuttle Pharmaceuticals (SHPH) Common Stock occurred at $4.67 per share for 1,033 shares on July 13, 2026, and $4.48 per share for 82,116 shares on July 14, 2026, both characterized as open-market sales.

Does HRT Financial LP still own SHPH Common Stock after these transactions?

After the July 14, 2026 transaction, HRT Financial LP reported holding 0 shares of Shuttle Pharmaceuticals Holdings, Inc. (SHPH) Common Stock directly. The final reported balance for this security following the last sale was shown as zero shares.

What is HRT Financial LP’s status in relation to Shuttle Pharmaceuticals (SHPH)?

HRT Financial LP is identified as a ten percent owner of Shuttle Pharmaceuticals Holdings, Inc. (SHPH). The reported transactions involve its directly held Common Stock position in the company, which was reduced to zero shares following the July 14, 2026 sale.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

X

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

HRT FINANCIAL LP

(Last) (First) (Middle)

3 WORLD TRADE CENTER, 175 GREENWICH STRE

76TH FLOOR

(Street)

NEW YORK NEW YORK 10007

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Shuttle Pharmaceuticals Holdings, Inc. [ SHPH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
07/09/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/13/2026		S		1,033	D	$4.67	60,238	D
Common Stock	07/14/2026		S		82,116	D	$4.48	0	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

	Adam Nunes	07/15/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)