STOCK TITAN

Opaleye-managed fund buys 1,563 Sol-Gel (SLGL) shares in open market

Filing Impact
(Moderate)
Filing Sentiment
(Positive)
Form Type
4

Rhea-AI Filing Summary

Sol-Gel Technologies Ltd. reported that entities managed by Opaleye Management Inc. made an open-market purchase of 1,563 ordinary shares on May 20, 2026 at a weighted average price of $64.4349 per share, with individual trades between $63.97 and $64.50. Following the transaction, an Opaleye-managed fund indirectly holds 490,000 shares, and a separately managed account holds 15,000 shares. Opaleye Management may be deemed to beneficially own these securities through its roles with the fund and managed account but disclaims beneficial ownership beyond its pecuniary interest.

Positive

  • None.

Negative

  • None.
Insider Opaleye Management Inc.
Role null
Bought 1,563 shs ($101K)
Type Security Shares Price Value
Purchase Ordinary Shares, par value NIS 1.00 per share. 1,563 $64.4349 $101K
holding Ordinary Shares, par value NIS 1.00 per share. -- -- --
Holdings After Transaction: Ordinary Shares, par value NIS 1.00 per share. — 490,000 shares (Indirect, By Opaleye, L.P.)
Footnotes (1)
  1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $63.97-$64.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price. Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Shares purchased 1,563 shares Open-market purchase on May 20, 2026
Weighted average price $64.4349 per share Price paid for 1,563 purchased shares
Price range $63.97–$64.50 per share Range of individual trade prices for the purchase
Fund holdings after trade 490,000 shares Ordinary shares held by Opaleye, L.P. after purchase
Managed account holdings 15,000 shares Ordinary shares held by separately managed account
Net share change 1,563 shares Net buy direction across reported transactions
open-market purchase financial
"transaction_action": "open-market purchase""
An open-market purchase is when an investor or a company buys shares on a public stock exchange at the going market price, rather than through a private deal. It matters to investors because these purchases change how many shares are available, can push the stock price up or signal confidence from large buyers, and often affect per-share metrics like earnings—think of it like someone buying lots of apples off a grocery shelf, reducing supply and potentially raising the price.
weighted average price financial
"The price reported in column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
beneficially own financial
"may be deemed to beneficially own the securities owned directly by the Fund."
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
pecuniary interest financial
"disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein"
separately managed account financial
"Securities owned by a separately managed account (the "Managed Account")."
A separately managed account (SMA) is a personalized investment portfolio owned by a single investor and run by a professional manager who buys and sells securities on that investor’s behalf. It matters to investors because an SMA offers tailored asset selection, tax handling, and transparency—like hiring a personal chef who prepares meals to your dietary needs rather than sharing a set menu—so you can align holdings with your goals and see exactly what you own.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Opaleye Management Inc.

(Last)(First)(Middle)
ONE BOSTON PLACE, 26TH FLOOR

(Street)
BOSTON MASSACHUSETTS 02108

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Sol-Gel Technologies Ltd. [ SLGL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
05/20/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares, par value NIS 1.00 per share.05/20/2026P1,563A$64.4349(3)490,000IBy Opaleye, L.P.(1)(4)
Ordinary Shares, par value NIS 1.00 per share.15,000IBy Managed Account(2)(4)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
3. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $63.97-$64.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price.
4. Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Opaleye Management, Inc., By: /s/ James Silverman, President05/22/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transaction did Opaleye Management report in Sol-Gel Technologies (SLGL)?

Opaleye-related entities bought 1,563 Sol-Gel shares. They executed an open-market purchase of 1,563 ordinary shares on May 20, 2026 at a weighted average price of about $64.43 per share, as disclosed in the Form 4 filing.

At what price did Opaleye entities buy Sol-Gel Technologies (SLGL) shares?

The weighted average purchase price was $64.4349 per share. The shares were bought in multiple trades, with individual transaction prices ranging from $63.97 to $64.50 inclusive, according to the Form 4 footnote disclosure.

How many Sol-Gel Technologies (SLGL) shares does the Opaleye fund hold after this transaction?

The Opaleye fund holds 490,000 Sol-Gel shares after the trade. The Form 4 states that Opaleye, L.P. owned 490,000 ordinary shares following the May 20, 2026 purchase, with Opaleye Management acting as the fund’s investment manager.

What are the indirect Sol-Gel (SLGL) holdings in the Opaleye managed account?

The managed account holds 15,000 Sol-Gel shares indirectly. A separately managed account associated with Opaleye Management is reported as owning 15,000 ordinary shares, with Opaleye serving as portfolio manager for that account.

How does Opaleye Management describe its beneficial ownership of Sol-Gel (SLGL) shares?

Opaleye may be deemed a beneficial owner but disclaims full ownership. The filing notes Opaleye Management may be deemed to beneficially own shares held by the fund and managed account, yet it formally disclaims beneficial ownership except for its pecuniary interest.

Was the Sol-Gel (SLGL) insider trade by Opaleye a purchase or sale?

The disclosed Sol-Gel insider transaction was a purchase. The Form 4 lists a transaction code P, described as an open-market or private purchase, totaling 1,563 ordinary shares acquired indirectly through Opaleye, L.P.