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SciSparc (NASDAQ: SPRC) collaboration advances MEAI-PEA depression patent bid

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Rhea-AI Filing Summary

SciSparc Ltd. reported that its majority-owned subsidiary NeuroThera Labs Inc., in collaboration with Clearmind Medicine Inc., has led to a patent application in Hong Kong for a new therapy to treat major depressive disorder. Clearmind filed the patent for a combination of its proprietary MEAI compound with Palmitoylethanolamide (PEA) sourced by NeuroThera. SciSparc holds an approximately 75% controlling interest in NeuroThera. The companies describe this MEAI‑PEA approach as a non‑hallucinogenic neuroplastogen that may offer a more accessible, safer and affordable alternative to existing antidepressants for depression, a condition affecting more than 332 million people globally.

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

Form 6-K

 

Report of Foreign Private Issuer

Pursuant to Rule 13a-16 or 15d-16

under the Securities Exchange Act of 1934

 

For the month of March 2026 (Report No. 3)

 

Commission File Number: 001-38041

 

SCISPARC LTD.

(Translation of registrant’s name into English)

 

20 Raul Wallenberg Street, Tower A,

Tel Aviv 6971916 Israel

(Address of principal executive offices)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

 

Form 20-F ☒     Form 40-F ☐

 

 

 

 

 

CONTENTS

 

On March 16, 2026, SciSparc Ltd. (the “Company”) issued a press release titled “SciSparc: NeuroThera Labs- Clearmind Medicine Collaboration Leads to Patent Application for Depression Therapy.” A copy of this press release is furnished herewith as Exhibit 99.1 to this Report of Foreign Private Issuer on Form 6-K (the “Report”) and is incorporated by reference herein.

 

This Report is incorporated by reference into the Company’s registration statements on Form F-3 (File Nos. 333-286099333-275305333-269839333-266047333-248670333-255408333-293167 and 333-293533) and on Form S-8 (File Nos. 333-278437333-225773333-286791 and 333-292952) filed with the SEC to be a part thereof from the date on which this report is submitted, to the extent not superseded by documents or reports subsequently filed or furnished. 

 

1

 

 

EXHIBIT INDEX

 

Exhibit No.   Description
99.1   Press release issued by SciSparc Ltd. titled “SciSparc: NeuroThera Labs- Clearmind Medicine Collaboration Leads to Patent Application for Depression Therapy.”

 

2

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

  SCISPARC LTD.
     
  By: /s/ Oz Adler
  Name:  Oz Adler
  Title: Chief Executive Officer and
Chief Financial Officer

 

Date: March 16, 2026

 

3

 

Exhibit 99.1

 

 

 

SciSparc: NeuroThera Labs- Clearmind Medicine Collaboration Leads to Patent Application for Depression Therapy

 

TEL AVIV, Israel, March 16, 2026 (GLOBE NEWSWIRE) -- SciSparc Ltd. (Nasdaq: SPRC) (“Company” or “SciSparc”), today announced that NeuroThera Labs Inc. (TSXV: NTLX) (“NeuroThera”), a clinical-stage pharmaceutical company focused on developing novel treatments for central nervous system (CNS) disorders, in which SciSparc holds a controlling interest of approximately 75%, has reported that pursuant to NeuroThera’s ongoing collaboration with Clearmind Medicine Inc. (“Clearmind”), a patent application has been filed by Clearmind with the Intellectual Property Department  in Hong Kong, China, for a innovative combination therapy designed to treat major depressive disorder (MDD).

 

This innovative treatment combines Clearmind’s proprietary 5-methoxy-2-aminoindane (MEAI) with Palmitoylethanolamide (PEA) sourced by NeuroThera.

 

The patent filing underscores the promise of this MEAI-PEA synergy as a non-hallucinogenic neuroplastogen option for combating depression, a condition affecting more than 332 million people globally, according to the World Health Organization article titled “Depressive Disorder (Depression)”, published in August 2025 Given the anticipated mechanism of action, this therapy could provide a more accessible, safer, and affordable alternative to existing antidepressants, including Selective Serotonin Reuptake Inhibitors (SSRIs) and other conventional options.

 

About SciSparc Ltd. (Nasdaq: SPRC):

 

The Company, through its majority-owned subsidiary NeuroThera Labs Inc., engages in clinical-stage pharmaceutical developments. SciSparc’s focus is on creating and enhancing a portfolio of technologies and assets based on cannabinoid pharmaceuticals. With this focus, the Company, together with its majority-owned subsidiary NeuroThera Labs Inc., are currently engaged in the following drug development programs based on THC and/or non-psychoactive CBD: SCI-110 for the treatment of Tourette syndrome, for the treatment of Alzheimer’s disease and agitation; and SCI- 210 for the treatment of ASD and status epilepticus. The Company, through NeuroThera Labs Inc., also owns a controlling interest in a subsidiary whose business focuses on the sale of hemp seed oil-based products on the Amazon.com Marketplace.

 

About NeuroThera Labs Inc.

 

NeuroThera Labs Inc. is a clinical-stage pharmaceutical company focused on developing novel therapeutics for central nervous system disorders and other underserved health conditions through collaborations and innovative combinations.

 

Forward-Looking Statements:

 

This press release contains forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995 and other Federal securities laws. For example, SciSparc uses forward-looking statements when it discusses the potential benefits and advantages from the therapy under the patent, and that therapy could provide a more accessible, safer, and affordable alternative to existing antidepressants, including SSRIs and other conventional options. Because such statements deal with future events and are based on SciSparc’s current expectations, they are subject to various risks and uncertainties and actual results, performance or achievements of SciSparc could differ materially from those described in or implied by the statements in this press release. The forward-looking statements contained or implied in this press release are subject to other risks and uncertainties, including those discussed under the heading “Risk Factors” in SciSparc’s Annual Report on Form 20-F, as amended, filed with the SEC on April 24, 2025, and in subsequent filings with the U.S. Securities and Exchange Commission. Except as otherwise required by law, SciSparc disclaims any intention or obligation to update or revise any forward-looking statements, which speak only as of the date they were made, whether as a result of new information, future events or circumstances or otherwise.

 

Investor Contact:


IR@scisparc.com
Tel: +972-3-6167055

 

FAQ

What did SciSparc Ltd. (SPRC) announce in this Form 6-K?

SciSparc announced that Clearmind Medicine filed a patent application in Hong Kong for a new depression therapy using MEAI combined with PEA sourced by NeuroThera, a clinical-stage company in which SciSparc holds about a 75% controlling interest.

What is the new depression therapy involving SciSparc’s subsidiary NeuroThera Labs?

The therapy combines Clearmind’s proprietary compound MEAI with Palmitoylethanolamide (PEA) provided by NeuroThera. It is described as a non-hallucinogenic neuroplastogen option intended to treat major depressive disorder and potentially offer advantages over existing antidepressant treatments.

Where was the patent application for the MEAI-PEA depression therapy filed?

Clearmind Medicine filed the patent application with the Intellectual Property Department in Hong Kong, China. The application covers the innovative MEAI-PEA combination therapy for major depressive disorder developed under the ongoing collaboration with NeuroThera Labs, SciSparc’s majority-owned subsidiary.

How is SciSparc Ltd. connected to NeuroThera Labs and Clearmind Medicine?

SciSparc holds an approximately 75% controlling interest in NeuroThera Labs, a clinical-stage pharmaceutical company. NeuroThera collaborates with Clearmind Medicine on novel CNS therapies, including the MEAI-PEA combination for depression, which led to Clearmind’s patent application in Hong Kong.

What broader market need does the MEAI-PEA depression therapy aim to address?

The therapy targets major depressive disorder, which affects more than 332 million people worldwide according to a World Health Organization article. It is intended as a potentially more accessible, safer and affordable alternative to existing antidepressants such as SSRIs and other conventional options.

What is SciSparc Ltd.’s core business focus beyond this depression patent news?

SciSparc, through NeuroThera Labs, focuses on clinical-stage cannabinoid-based pharmaceuticals. Its programs include SCI-110 for Tourette syndrome, Alzheimer’s disease and agitation, and SCI-210 for autism spectrum disorder and status epilepticus, alongside a hemp seed oil products business on the Amazon.com Marketplace.

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