[Form 4] Twist Bioscience Corp Insider Trading Activity

Rhea-AI Filing Summary

Paula Green, who serves as SVP of Human Resources and a director at Twist Bioscience Corp (TWST), reported a mandated sell-to-cover transaction tied to the vesting of restricted stock units. On 10/02/2025 she disposed of 140 shares of common stock at $29.161 per share to satisfy tax withholding, leaving her with 124,402 shares beneficially owned after the sale. The Form 4 was signed by an attorney-in-fact on 10/06/2025.

The filing explicitly states the sale was not a discretionary trade but a company-mandated sale under the issuer's equity plan to cover tax obligations arising from RSU vesting. No options, warrants, or other derivative transactions are reported on this form.

Positive

• Transaction was a sell-to-cover for taxes tied to RSU vesting, indicating routine administrative activity rather than discretionary liquidation
• Reporting person retains significant ownership with 124,402 shares remaining after the transaction

Negative

• None.

Insights

Equity Compensation Analyst

Mandated sell-to-cover of RSUs reduced holdings slightly; no discretionary insider selling signaled.

The transaction shows 140 shares sold at $29.161 to satisfy tax withholding from RSU vesting, a routine administrative outcome when an issuer elects a "sell-to-cover" method. The remaining beneficial ownership of 124,402 shares remains intact and is reported as a direct holding.

Key dependencies include the company’s equity plan rules and upcoming RSU vesting schedules; watch for additional Form 4 filings around subsequent vesting dates within the next 12 months if the issuer continues this withholding method.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Green Paula

(Last) (First) (Middle)

C/O TWIST BIOSCIENCE CORPORATION

681 GATEWAY BLVD.

(Street)

SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Twist Bioscience Corp [ TWST ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	SVP of Human Resources

3. Date of Earliest Transaction (Month/Day/Year)
10/02/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	10/02/2025		S		140(1)	D	$29.161	124,402	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents the number of shares required to be sold by the Reporting Person to cover tax withholding obligations in connection with the vesting of Restricted Stock Units. These sales are mandated by the Issuer's election under its equity incentive plans to require the satisfaction of a tax withholding obligation to be funded by a "sell to cover" transaction and do not represent discretionary trades by the Reporting Person.

Remarks:

	/s/ Kendra Fox, as Attorney-in-Fact for Paula Green	10/06/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Paula Green report on the Form 4 for TWST?

The Form 4 reports a disposal of 140 shares on 10/02/2025 at $29.161 per share to cover tax withholding from RSU vesting.

Was this sale a discretionary trade by the insider (Paula Green)?

No. The filing states the sale was a mandated sell-to-cover required to satisfy tax withholding under the issuer’s equity incentive plan and did not represent a discretionary trade.

How many shares does Paula Green beneficially own after the transaction?

She beneficially owns 124,402 shares following the reported transaction.

What is Paula Green’s role at Twist Bioscience (TWST)?

She is identified as SVP of Human Resources and a director of the company.

Does the Form 4 report any derivative transactions for Paula Green?

No derivative securities (options, warrants, or convertible instruments) are reported on this Form 4.