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Kura Oncology, Inc. (KURA) filed an 8-K to disclose that, on June 27, 2025, it executed a Co-Promotion and Medical Affairs Agreement with Kyowa Kirin, Inc. covering U.S. commercialization of its oral menin inhibitor ziftomenib for acute myeloid leukemia and other hematologic malignancies. The agreement operates under the previously announced November 20, 2024 Collaboration and License Agreement.
Main commercial terms
- Co-promotion rights: Kyowa Kirin US will handle up to a specified share of sales details and must meet minimum detailing thresholds with qualified representatives.
- Cost sharing: Both companies will split all U.S. co-promotion and medical affairs expenses 50/50.
- Medical affairs leadership: Kura will lead U.S. medical affairs, with input from Kyowa Kirin; the parties will jointly craft a health economics and outcomes research strategy.
- Term & termination: The pact lasts until the earlier of (i) mutual decision to cease commercialization or (ii) expiration of the U.S. collaboration term—defined as the latest of patent expiry, regulatory exclusivity expiry, or 10 years after first commercial sale. It terminates automatically if the broader Collaboration Agreement ends, and either side may end it for an uncured material breach.
The full agreement, with confidential portions redacted, will be filed as an exhibit to Kura’s Form 10-Q for the quarter ending June 30, 2025.