STOCK TITAN

XORTX Therapeutics (NASDAQ: XRTX) appoints Depesh Narotam as independent director

(Neutral)
(Neutral)
Form Type
6-K

Rhea-AI Filing Summary

XORTX Therapeutics Inc., a late-stage clinical pharmaceutical company focused on therapies for gout and progressive kidney disease, appointed Depesh Narotam, age 43, to its board of directors as an independent director effective July 27, 2026.

He will also serve on the board’s Compensation, Governance and Nominating Committee. Narotam has over 20 years of financial services experience, including 16 years at Westminster Savings Credit Union and his current role at Vancity. XORTX highlights a pipeline of three clinically advanced programs and additional earlier-stage kidney disease programs, and notes forward-looking risks around capital needs, regulatory approvals and talent retention.

Positive

  • None.

Negative

  • None.

Filing Explained

The appointment of Depesh Narotam took effect July 27, 2026; XORTX’s board determined that he is an independent director under Nasdaq listing standards and Canadian securities laws, changing the board’s membership with an independent director.

Director age 43 Age of Depesh Narotam at appointment as director
Financial services experience over 20 years Duration of Depesh Narotam's career in financial services
Tenure at Westminster Savings Credit Union 16 years Time Mr. Narotam spent at Westminster Savings Credit Union
Clinically advanced programs three products Number of clinically advanced products in XORTX's development pipeline
Appointment effective date July 27, 2026 Effective date of Mr. Narotam's appointment to the board
independent director regulatory
"appointment of Depesh Narotam to the board of directors as an independent director"
An independent director is a member of a company's board of directors who is not involved in the company's day-to-day operations and has no significant relationships with the company that could influence their judgment. Their role is to provide unbiased oversight and ensure the company is managed in the best interests of all shareholders. This helps build trust and confidence among investors by promoting transparency and accountability.
Compensation, Governance and Nominating Committee regulatory
"appointed to serve as a member of the Compensation, Governance and Nominating Committee"
forward-looking statements regulatory
"This press release contains "forward-looking statements" within the meaning"
Forward-looking statements are predictions or plans that companies share about what they expect to happen in the future, like estimating sales or profits. They matter because they help investors understand a company's outlook, but since they are based on guesses and assumptions, they can sometimes be wrong.
Risk Factors regulatory
"review the disclosures contained under the heading "Risk Factors" in the Company's Annual Report"
Risk factors are elements or conditions that could cause an investment's value to decrease or lead to potential losses. They are like warning signs or obstacles that can affect the success of an investment, making it uncertain or more unpredictable. Recognizing risk factors helps investors understand the possible challenges and make more informed decisions.
purine metabolism medical
"advance products that target aberrant purine metabolism and xanthine oxidase"
xanthine oxidase medical
"target aberrant purine metabolism and xanthine oxidase to decrease or inhibit production of uric acid"
Xanthine oxidase is a naturally occurring enzyme — think of it as a tiny chemical machine in cells — that helps break down purines into uric acid and in the process produces reactive molecules. Investors care because blocking this enzyme can lower uric acid levels and reduce damaging oxidative byproducts, making it a key drug target for conditions like gout and certain cardiovascular or kidney issues; progress or setbacks in drugs against this enzyme can affect clinical, regulatory, and market outcomes.

AI-generated analysis. How Rhea-AI works. Not financial advice.

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google
Add on Google
Learn about SEC filing dates

FAQ

Who did XORTX Therapeutics (XRTX) appoint to its board and in what role?

XORTX Therapeutics appointed Depesh Narotam to its board as an independent director effective July 27, 2026. He brings over 20 years of financial services experience and will contribute to governance and oversight at the company.

What committee will Depesh Narotam join at XORTX Therapeutics (XRTX)?

Depesh Narotam will serve on XORTX’s Compensation, Governance and Nominating Committee. This committee oversees executive pay, board governance practices, and director nominations, giving Narotam direct involvement in key corporate governance decisions.

What is Depesh Narotam’s professional background relevant to XORTX Therapeutics (XRTX)?

Depesh Narotam has over 20 years in financial services, including 16 years at Westminster Savings Credit Union and a role at Vancity since December 2020. His expertise centers on debt financing, real estate lending, market expansion and strategic partnerships.

What drug development programs does XORTX Therapeutics (XRTX) highlight?

XORTX describes three clinically advanced products: XRx-026 for gout, XRx-008 for ADPKD, and XRx-101 for acute kidney and organ injury, plus earlier-stage programs XRx-225 and VB4-P5 targeting diabetic nephropathy and other kidney diseases.

What key risks and forward-looking factors does XORTX Therapeutics (XRTX) emphasize?

XORTX notes risks including its need for additional capital, uncertainty around regulatory approvals for XRx-026 and other candidates, an evolving U.S. and Canadian regulatory environment, and challenges in attracting and retaining qualified personnel, including its newly appointed director.

How does XORTX Therapeutics (XRTX) describe its therapeutic focus?

XORTX focuses on targeting aberrant purine metabolism and xanthine oxidase to decrease uric acid production. Its goal is to develop medications that improve quality of life for individuals with gout, progressive kidney disease and related serious conditions.
 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Form 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 
UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of July 2026

Commission File Number: 001-40858

XORTX Therapeutics Inc.

3710 – 33rd Street NW, Calgary, Alberta, Canada T2L 2M1

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.
Form 20-F [ X ]      Form 40-F [   ]


EXHIBIT INDEX

 

Exhibit Description
   
99.1 News release dated July 29, 2026.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

  XORTX Therapeutics Inc.    
    
   
Date: July 29, 2026 By:     /s/ Allen Davidoff    
  Name: Allen Davidoff
  Title: Chief Executive Officer
   

EXHIBIT 99.1

XORTX Appoints New Director

CALGARY, Alberta, July 29, 2026 (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. ("XORTX" or the “Company”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat gout and progressive kidney disease, is pleased to announce the appointment of Depesh Narotam to the board of directors as an independent director.

Depesh Narotam has been in the financial services industry for over 20 years. He has developed considerable expertise in debt financing, delivering strategic lending solutions to a diverse client base. Over the course of his career Depesh has developed a comprehensive understanding of various sectors specifically the real estate lending landscape where he has been responsible for market expansion and strategic partnerships to those that have benefited from enhanced market presence and long term performance.

Depesh Narotam

Mr. Narotam, age 43, was appointed as a director of the Company effective July 27, 2026. The board of directors has determined that Mr. Narotam is an independent director under applicable Nasdaq listing standards and Canadian securities laws. Mr. Narotam has also been appointed to serve as a member of the Compensation, Governance and Nominating Committee of the board of directors. Mr. Narotam is a resident of British Columbia, Canada and has served as a Mortgage Development Manager since December 2020 at Vancity, Canada's largest community-based credit union and a member-owned financial co-operative. Prior to joining Vancity, Mr. Narotam spent 16 years with Westminster Savings Credit Union (now Prospera Credit Union) where he held various positions in financial services including Mortgage Specialist and Business Development Manager.

About XORTX Therapeutics Inc.

XORTX is a pharmaceutical company with three clinically advanced products in development: 1) our lead program XRx-026 program for the treatment of gout; 2) XRx-008 program for ADPKD; and 3) XRx-101 for acute kidney and other acute organ injury associated with respiratory virus infections. In addition, the Company is developing XRx-225, a pre-clinical stage program for Type 2 diabetic nephropathy and recently acquired VB4-P5 program, which is currently at the pre-IND stage of development and targets both rare and prevalent forms of kidney disease. XORTX is working to advance products that target aberrant purine metabolism and xanthine oxidase to decrease or inhibit production of uric acid. At XORTX, we are dedicated to developing medications that improve the quality of life and health of individuals with gout and other important diseases.

For more information, please contact:

Allen Davidoff, Co-CEO Mika Grasso, Co-CEO
adavidoff@xortx.com mgrasso@xortx.com
+1 403 455 7727 +1 949 244 6011


Neither the TSX Venture Exchange nor Nasdaq has approved or disapproved the contents of this news release. No stock exchange, securities commission or other regulatory authority has approved or disapproved the information contained herein.

Forward Looking Statements

This press release contains "forward-looking statements" within the meaning of the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, as well as "forward-looking information" within the meaning of applicable Canadian securities laws. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "expect," "estimate," "plan," "intend," "will," "designed to," "positions," and similar expressions, and include all statements that are not statements of historical fact. These forward-looking statements include, but are not limited to, statements regarding: the appointment of Mr. Narotam to the Company's board of directors; his anticipated contributions to the Company; and the advancement of the Company's development programs and its strategy.

Forward-looking statements are based on the Company's current expectations and assumptions and are subject to known and unknown risks, uncertainties, and other factors that could cause actual results, performance, or achievements to differ materially from those expressed or implied by such statements. Such risks and uncertainties include, among others: the Company's need for, and ability to obtain, additional capital to fund its development programs and operations; the Company's ability to advance, and obtain regulatory approval for, the XRx-026 program and its other product candidates on the timelines currently anticipated, or at all; the evolving regulatory environment applicable to the Company's business in the United States and Canada; and the Company's ability to attract and retain qualified personnel, including its newly appointed director.

For a more detailed discussion of these and other risks and uncertainties, investors should review the disclosures contained under the heading "Risk Factors" in the Company's Annual Report on Form 20-F for the fiscal year ended December 31, 2025, and in the Company's subsequent Reports of Foreign Private Issuer on Form 6-K, each as filed with or furnished to the SEC and available at www.sec.gov, as well as in the Company's continuous disclosure documents filed with the Canadian securities regulatory authorities and available at www.sedarplus.ca.

The forward-looking statements in this press release speak only as of the date hereof. Except as required by law, the Company undertakes no obligation to update or revise any forward-looking statement, whether as a result of new information, future events, or otherwise. Readers are cautioned not to place undue reliance on these forward-looking statements.

Filing Exhibits & Attachments

1 document