UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington, D.C. 20549
Form
6-K
REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO
RULE 13a-16 OR 15d-16
UNDER THE SECURITIES EXCHANGE ACT OF 1934
For the month of September 2026
Commission File Number: 001-40858
XORTX
Therapeutics Inc.
3710 – 33rd Street NW, Calgary, Alberta,
Canada T2L 2M1
Indicate by check mark whether the registrant files or will file annual
reports under cover Form 20-F or Form 40-F.
Form 20-F ☒ Form 40-F ☐
Re-Engagement of IR Agency LLC
As previously disclosed, on May 13, 2026, XORTX Therapeutics Inc. (the
“Company”) entered into an investor relations and marketing agreement (the “Original IR Agreement”)
with IR Agency LLC (“IR Agency”) in connection with the Company’s US$5,000,000 public offering completed on May
19, 2026, and US$2,500,000 of the net proceeds of that offering was allocated to IR Agency for marketing and advertising services. Effective
August 7, 2026, the Company and IR Agency mutually agreed to terminate and rescind the Original IR Agreement, all services under it were
discontinued, and the full amount previously paid to IR Agency was returned to the Company on August 14, 2026.
At that time, the Company elected to postpone its investor relations
and marketing program while it completed its previously announced voluntary delisting from the TSX Venture Exchange (the “TSXV”).
The Company also disclosed its intention to re-engage IR Agency following completion of the voluntary delisting when deemed appropriate
by management and the board of directors.
On August 28, 2026, the Company received final approval from the
TSXV for the voluntary delisting of its common shares, and the delisting took effect as of close of business September 1, 2026. The Company’s
common shares continue to be listed on the Nasdaq Capital Market under the symbol “XRTX”.
On September 2, 2026, following completion of the voluntary delisting
and consistent with its previously disclosed intention, the Company entered into a revised consulting agreement (the “IR Agreement”)
with IR Agency, pursuant to which IR Agency will provide marketing and advertising services to communicate information about the Company
to the financial community, including the creation of company profiles and media distribution of Company news. The IR Agreement has a
term of three months commencing September 3, 2026 and provides for a maximum of ten news distribution campaigns during the term, subject
to extension by mutual agreement of the parties. In consideration for the services, the Company has agreed to pay IR Agency a fee of US$2,500,000,
payable in advance by wire transfer on or before September 2, 2026, which is being funded from the amounts returned to the Company by
IR Agency in August 2026 and reserved by the Company for future investor relations expenditures. Under the terms of the IR Agreement,
the fee is fully earned upon receipt and is non-refundable, including upon termination. Either party may terminate the IR Agreement at
any time on written notice.
The foregoing description of the IR Agreement does not purport to be
complete and is qualified in its entirety by reference to the full text of the IR Agreement, a copy of which is furnished as Exhibit 99.1
to this Report on Form 6-K and is incorporated herein by reference.
Incorporation by Reference
This Report on Form 6-K, including Exhibit 99.1, is hereby incorporated
by reference into the Company’s Registration Statements on Form F-3 (File No. 333-269429) and Form S-8 (File No. 333-268034), and
into any prospectus forming a part thereof, to be a part thereof from the date on which this Report is furnished, to the extent not superseded
by documents or reports subsequently filed or furnished.
Forward-Looking Statements
This Report on Form 6-K contains forward-looking statements within
the meaning of applicable United States and Canadian securities laws, including statements regarding the timing, scope and conduct of
the Company’s investor relations and marketing program under the IR Agreement, the anticipated benefits of the voluntary delisting
from the TSXV, and the Company’s continued listing on the Nasdaq Capital Market. Forward-looking statements are based on management’s
current expectations and are subject to risks and uncertainties that could cause actual results to differ materially, including the risk
that the investor relations program does not achieve its intended objectives, the Company’s ongoing compliance with Nasdaq continued
listing standards, the Company’s need for additional capital, and the risks described in the Company’s Annual Report on Form
20-F for the year ended December 31, 2025 and its other reports filed with or furnished to the U.S. Securities and Exchange Commission,
available at www.sec.gov, and filed with Canadian securities regulators, available on SEDAR+. Except as required by applicable law, the
Company undertakes no obligation to update any forward-looking statement.
EXHIBIT INDEX
| Exhibit |
|
Description |
| 99.1 |
|
Consulting Agreement, dated September 2, 2026, between XORTX Therapeutics Inc. and IR Agency LLC. |
SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
| |
XORTX Therapeutics Inc. |
| |
|
| Date: September 4, 2026 |
By: |
/s/ Mika Grasso |
| |
Name: |
Mika Grasso |
| |
Title: |
Co-Chief Executive Officer |
Exhibit 99.1

CONSULTING
AGREEMENT
IR Agency LLC (the “Consultant” or
“IR Agency”) is pleased to provide certain consulting services to XORTX Therapeutics Inc (XRTX) (“you,” “Client”
or “Company”) as more fully described in this agreement (the “Agreement”). This Agreement sets forth the terms
and conditions pursuant to which Company engages Consultant to provide such services.
| (a) | Commencing on 9/3/2026, Consultant will provide marketing and advertising services (“Advertising”
or “Services”) to communicate information about the Company (trading symbol: XRTX to the financial community including, but
not limited to, creating company profiles and media distribution. |
| | | |
| (b) | Consultant does not make any representation about and assumes no responsibility for the response by the
market, if any, to the public release of Advertising for the Company. For avoidance of doubt, Client acknowledges that Consultant assumes
no responsibility for and does not make any representation, guarantee or promise that in response to the public release of Advertising
for the Company, the trading volume will increase or the trading price of [XRTX] will rise, or in the event of a increase in trading
volume or rise in price, the amount or duration of any such increase in trading volume or rise in price |
| (c) | Client acknowledges that Consultant carries no professional licenses. Consultant will not participate
in discussions or negotiations with potential investors. Consultant will not solicit orders, make recommendations or give investment advice.
Consultant will not effect transactions of securities for potential investors or anyone else. Consultant and Client agree that Consultant
is not being engaged for, and is not permitted to engage in, activities that would give rise to Consultant being required to register
federally or in any state or other jurisdiction as a broker or an investment advisor. If a financial intermediary expresses interest in
the Company to Consultant, Consultant will refer the intermediary to the Company. In providing services under the Agreement, Consultant
agrees to comply in all materials respects with all applicable U.S. securities laws. Client acknowledges and agrees that (a) it and its
affiliates each have relied and will continue to rely on the advice of its own legal, regulatory, and securities law advisors for all
matters and (b) neither Client nor any of its affiliates has received, or has relied upon, the advice of Consultant or any of its affiliates
or their counsel regarding legal, regulatory, or securities law matters. |
| (d) | The Services of Consultant shall not be exclusive to Client, and Client acknowledges that Consultant will
be performing similar Services for other clients and Consultant shall be free to perform Services for such other persons. |
| 2. | Independent Contractor. Client and Consultant agree that Consultant shall perform its duties under
this Agreement as an independent contractor. Nothing contained herein shall be considered as creating a relationship of agent-principal,
employer-employee or joint venturers between Consultant and either Client. |
| (a) | As consideration for the performance of the Services hereunder, upon the
date of the execution and delivery of this Agreement, Client shall pay to Consultant the sum of Two Million Five Hundred Thousand Dollars
($2,500,000) by 9/02/2026 in cash via Bank Wire Transfer for providing the Services of Marketing of News Distribution during a maximum
of 10 News releases during a 3 Months term starting on 9/3/2026. All fees
are fully earned upon receipt and are strictly non-refundable under any circumstances, including termination, dissatisfaction, or results.
Client waives any right to refund, offset, or chargeback. Client has right to cancel before any new quarter begins (client also has right
to request that agreement be extended during months that no news distribution is performed) |
| (b) | Unless otherwise provided in this Agreement, all other services, including out-of-scope assignments, rendered
by Consultant shall be subject to additional compensation under a separate agreement between Consultant and Company. Consultant shall
be responsible for all out-of-pocket expenses incurred or paid in connection with its performance of the Services hereunder. |
| (a) | The term of this Agreement shall commence on the start date and continue for a period of 3 Months or 10
releases of Marketing Distribution News Campaigns (the “Term”) unless otherwise extended by mutual agreement of the parties
(the “Extended Term”). This Agreement may be terminated, with or without cause, by either Client or Consultant at any time
by written notice to the other Party. If the Agreement is terminated by Client during the Term for any reason, Client will not be entitled
to return of any of the compensation. If Client files for bankruptcy, becomes insolvent or is in material breach of this Agreement (“Cause”),
Consultant may terminate the Agreement and Client will not be entitled to the return of any of the compensation. Consultant may immediately
suspend or terminate Services if it believes continued performance may expose it to legal, regulatory, or reputational risk. No refund
shall be owed in such event. |
| (b) | In the event Client elects to purchase and Consultant agrees to supply additional Services during the
Term or the Extended Term of this Agreement, the terms and condition of this Agreement will apply to such additional Services. |
| (a) | In connection with Consultant’s performance of its Services, Consultant will rely on Company’s
press releases and Company’s most recent reports, if any, filed with the Securities and Exchange Commission (collectively, the “Company
Information”). In this regard, Company agrees to make all filings required by the exchange act and all other applicable laws, in
each case on a timely basis in accordance with such laws. Client hereby grants to Consultant the right to use the name and service marks
of Company in its Services. Company will be entitled to require that certain or all materials created by Consultant in performing its
Services be submitted to Company for its review and approval, such approval not to be unreasonably withheld, conditioned or delayed. |
| (b) | Client hereby acknowledges and agrees that, in performing its Services hereunder, Consultant will be using
and relying on the Company Information without independent verification thereof. Consultant will also be under no obligation to determine
whether there have been, or to investigate any changes in, such information. Consultant will be entitled to submit any materials created
by Consultant to Company for its review and approval, such approval not to be unreasonably withheld, conditioned, or delayed. Client represents
and warrants that that the Company Information and all information provided by Company or its affiliate or representatives to Consultant
shall, at the time provided, not contain any untrue statement or material fact or omit to state a material fact necessary in order to
make the statement made, in light of the circumstances under which they were made, not misleading. |
| (c) | Client, by its authorization or approval of the Advertisement, represents and warrants to Consultant that,
to its knowledge, the Advertisement is complete and correct in all material respects and does not contain any untrue statement of a material
fact or omit to state a material fact necessary to make the statements therein not misleading. Client agrees to promptly notify Consultant
upon the occurrence of any material adverse change in the business or affairs of the Company or upon the occurrence of any event which
causes Client to believe that the Advertisement contains any untrue statement of a material fact or omits to state a material fact necessary
to make the statements therein not misleading. |
| (d) | Client acknowledges that Services are promotional
in nature. Consultant makes no guarantees regarding trading volume, stock price, investor interest, or financial outcomes. All market
risk is borne solely by Client. |
| (e). | Paid Promotion Disclosure (SEC 17(b)) Consultant may
include disclosures required by securities laws, including compensation disclosure. Client agrees not to restrict or alter such disclosures. |
| 6. | Securities Laws. Client represents and warrants that the Company Information and all information
provided by Company or its affiliates or representatives complies in all respects with the U.S. federal and applicable state securities
laws, and are not and will not be or constitute a part of any activity that is or may be deemed to be illegal under the U.S. federal or
applicable state securities laws, including, without limitation, being a part of any illegal offering, illegal pump-and-dump, illegal
scalping, illegal touting schemes, or an effort to assist with a violation of any court order including, but not limited to, any order
banning or limiting a person’s involvement in the securities markets. |
| 7. | Work Product. All information and materials produced for Client shall be the property of Consultant,
free and clear of all claims thereto by Client, and Client shall have no claim of authorship therein. Consultant shall retain all right,
title, and interest in and to, including any intellectual property rights with respect to, any data, designs, processes, specifications,
software, applications, course, code, object code, utilities, methodologies, know-how, materials, information and skills (and any derivative
works, modifications and enhancements thereto) owned, acquired or developed by or for Consultant’s databases. |
| 8. | Confidentiality. The parties agree to hold each other’s Proprietary or Confidential Information
in strict confidence. “Proprietary or Confidential Information” shall include, but is not limited to, written or oral contracts,
trade secrets, know-how, business methods, business policies, memoranda, reports, records, computer retained information, notes, or financial
information. Proprietary or Confidential Information shall not include any information which: (i) is or becomes generally known to the
public by any means other than a breach of the obligations of the receiving party; (ii) was previously known to the receiving party or
rightly received by the receiving party from a third party; (iii) is independently developed by the receiving party; or (iv) is subject
to disclosure under court order or other lawful process. The parties agree not to make each other’s Proprietary or Confidential
Information available in any form to any third party or to use each other’s Proprietary or Confidential Information for any purpose
other than as specified in this Agreement. Each party’s Proprietary or Confidential Information shall remain the sole and exclusive
property of that party. The parties agree that in the event of use or disclosure by the other party other than as specifically provided
for in this Agreement, the non-disclosing party may be entitled to equitable relief. Notwithstanding termination or expiration of this
Agreement, the parties acknowledge and agree that their obligations of confidentiality with respect
to Proprietary or Confidential Information shall continue in effect for a total period of three (3) years from the termination date. |
| 9. | Non-Public Material Information. Consultant acknowledges that to prepare appropriate Advertising
in a timely manner it may be made aware of price sensitive or confidential information that has not been publicly disclosed yet. Consultant
confirms that it is fully aware of its obligations in relation to such information and will ensure that the confidentiality of such information
is maintained at all times and that it, and its employees and contractors, are all fully aware of and comply with, all appropriate securities
laws and regulations in relation to insider trading and related matters. |
| 10. | Covenant Not to Sue. Client agrees that it will not file any suit, claim, proceeding or complaint
against Consultant arising out of or based on the failure of the trading volume of the stock to increase or price to rise, or to maintain
any increase in trading volume or rise in stock price as may be occur, as a result of or in response to the public release of Advertising
for the Company or Consultant’s provision of services under this Agreement. |
| 11. | Limitation of Liability. Consultant shall not be liable to Client or any other person for any damages
in connection with the provision of services under the Agreement, whether because of Consultant’s negligence or otherwise, and regardless
of the form of action, except in the event of Consultant’s deliberate fault or gross negligence. Nevertheless, regardless of the
form of action, whether in contract, tort or otherwise, Consultant shall not be liable to Client for any lost profits, business interruption,
or for any indirect, incidental, special, consequential, exemplary or punitive damages arising out of or relating to this Agreement, nor
shall Consultant’s aggregate liability for any damages arising out of this Agreement exceed the compensation paid by Client to Consultant. |
| 12. | Indemnification. Client shall indemnify and hold Consultant harmless from and against any and all
actions, claims, investigations (including but not limited to any formal or informal investigations brought by any state or federal regulator
and any subpoenas or requests for documents, information or testimony issued in connection therewith), liabilities, losses, or damages
arising from the preparation, presentation or dissemination of any Advertising covered by this Agreement including, but limited to, the
costs of defense and attorneys’ fees. You will also indemnify Consultant from and against all losses, expenses (including costs
and attorneys’ fees) and all manner of actions, claims and judgments sustained by or made against Consultant in connection with
your use or misuse of the Service, any medium used with the Service, violation of this Agreement, or based upon any alleged violation
of any statute, ordinance, code, or regulation. |
| 13. | Notices. Any notice or other communication required or permitted to be given to either party hereunder
shall be in writing and shall be given to such party at such party’s address set forth below or such other address as such party
may hereafter specify by notice in writing to the other party. Any such notice or other communication shall be addressed as aforesaid
and given by (a) certified mail, return receipt requested, with first class postage prepaid, (b) hand delivery, or (c) via
electronic communication (i.e., e-mail) or (d) reputable overnight courier. Any notice or other communication will be deemed to have been
duly given (i) on the fifth (5) day after mailing, provided receipt of delivery is confirmed, if mailed by certified mail, return receipt
requested, with first class postage prepaid, (ii) on the date of Service if served personally or (iii) on the business day after delivery
to an overnight courier service or by sending of an electronic communication, provided the notifying party specifies next day delivery
and receipt of delivery has been confirmed: |
If to the Client:
Email:
If to Consultant:
IR Agency LLC
23 Downing Street, Newark
NJ 07105
E-mail: [Raf@ir.agency]
| 14. | Waiver of Breach. Any waiver by either party of a breach of any provision of this Agreement by
the other party shall not operate or be construed as a waiver of any subsequent breach by any party. |
| 15. | Assignment. Neither this Agreement nor any of the rights, interests or obligations hereunder may
be assigned by either party hereto without the prior written consent of the other party, which will not be delayed or withheld unreasonably;
provided that Client shall not be required to consent to any assignment by Consultant of its cash and compensation payable pursuant to
this Agreement. Any assignment without such consent, when required, shall have no legal validity; subject to the foregoing, this Agreement
and all of the provisions hereof will be binding upon and inure to the benefit of the parties to this Agreement and their respective successors
and permitted assigns. |
| 16. | Governing Law and Jurisdiction. All disputes shall be resolved by binding arbitration administered
by the AAA in New Jersey. The parties waive any right to trial by jury and agree no class actions may be brought. |
| 17. | Entire Agreement. This Agreement contains the complete agreement between the parties with respect
to the subject matter hereof and supersedes any prior proposals, understandings, agreements or representations by or between the parties,
written or oral. Client acknowledges it has not relied on any statements or representations outside of this Agreement. |
| 18. | Severability. Whenever possible, each provision of this Agreement will be interpreted in such manner
as to be effective and valid under applicable law, but if any provision of this Agreement is held by any court of competent jurisdiction
to be prohibited by or invalid under applicable law, such provision will be ineffective only to the extent of such prohibition or invalidity,
without invalidating the remainder of such provision or the remaining provisions of this Agreement. |
| 19. | Waiver and Modification. Any waiver, alteration, or modification of any of the provisions of this
Agreement shall be valid only if made in writing through an amendment of this Agreement and signed by the parties hereto. |
| 20. | Acceptance. Please confirm that the foregoing is in accordance with Company’s understanding
by signing and returning this Agreement, which will thereupon constitute a binding Agreement between the Company and IR Agency, LLC as
of the date of your execution. The undersigned officers of IR Agency, LLC and Company represent that they have the authority to bind IR
Agency and Company, respectively. This Agreement may be executed in counterparts and with electronic or facsimile signatures. |
| IR Agency LLC |
|
| |
|
| By: |
/s/ Rafael Pereira |
|
| Print Name: |
Rafael Pereira |
|
| |
|
| By: |
/s/ Mika Grasso |
|
| Print Name: |
XORTX Therapeutics Inc |
|
| Position: |
Mika Grasso / Co-Chief Executive Officer |
|
| |
|
|
| Date: |
9/2/2026 |
|
| United States |
|