UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 6-K
REPORT OF FOREIGN ISSUER
PURSUANT TO RULE 13a-16 OR 15d-16 OF
THE SECURITIES EXCHANGE ACT OF 1934
For the month of September 2026
Commission file number: 001-38639
111, Inc.
10th Floor, T1, Yuzhongxin, No. 268 Yubei Road
Pudong New Area
Shanghai, 201204
The People’s Republic of China
(Address of principal executive offices)
Indicate by check mark whether the registrant files or will file annual
reports under cover Form 20-F or Form 40-F. Form 20-F ☒ Form 40-F
☐
EXHIBIT INDEX
| Exhibit No. |
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Description |
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| 99.1 |
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111 Inc. Receives Unsolicited Preliminary Non-Binding Proposal to Acquire the Company |
| 99.2 |
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The Non-binding Proposal Letter |
Signature
Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
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111, INC. |
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| Date: |
September 17, 2026 |
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By: |
/s/ Junling Liu |
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Name: |
Junling Liu |
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Title: |
Chief Executive Officer |
EXHIBIT 99.1

111 Inc. Receives Unsolicited Preliminary
Non-Binding Proposal to Acquire the Company
SHANGHAI,
September 17, 2026 /PRNewswire/
-- 111 Inc. ( "111" or the "Company") (NASDAQ: YI), a leading tech-enabled healthcare platform company in China, today
announced that its Board of Directors (the "Board") has received an unsolicited preliminary non-binding proposal letter
(the "Proposal") dated September 16, 2026 jointly submitted by Dr. Gang Yu, co-founder and co-chairman of the Company, Mr. Junling
Liu, co-founder, co-chairman and chief executive officer of the Company (collectively, the “Co-Founders”) and Huadeng Tech
BioArray Ventures Ltd (the “Sponsor,” and together with the Co-Founders, the “Buyer Group”), proposing to acquire
all of outstanding Class A ordinary shares (the “Class A Shares”) of the Company, including Class A Shares represented by
American depositary shares (“ADSs,” each representing twenty Class A Shares), that are not currently owned by the Buyer Group
in a going-private transaction at a proposed purchase price of US$0.226 per Class A Share or US$4.52 per ADS in cash.
According
to the Proposal, the Buyer Group intends to fund the consideration payable
to consummate the transactions contemplated in the Proposal with equity capital. Equity financing is expected to be provided in the form
of rollover equity in the Company and cash contributions from the Sponsor or its affiliates.
The Board cautions the Company's shareholders
and others considering trading the Company's securities that the Board has just received the Proposal and has not had an opportunity to
carefully review or evaluate the Proposal and its terms, or make any decision with respect to the Company's response to the Proposal.
There can be no assurance that any definitive offer will be received, that any definitive agreement will be executed relating to the Proposal
or that this or any other transaction will be approved or consummated. The Company does not undertake any obligation to provide any updates
with respect to this or any other transaction, except as required under applicable law.
Additional Information about the Proposal
The Company will furnish to the U.S. Securities
and Exchange Commission (the "SEC") a current report on Form 6-K regarding the Proposal, which will include the proposal letter
as an annex thereto. All parties desiring details regarding the Proposal should review these documents, which will be available at the
SEC's website (http://www.sec.gov).
Forward-Looking Statements
This press release contains forward-looking
statements. These statements constitute "forward-looking" statements within the meaning of Section 21E of the Securities Exchange
Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements
can be identified by terminology such as "will," "expects," "anticipates," "future," "intends,"
"plans," "believes," "estimates," "target," "confident" and similar statements. Among
other things, the Business Outlook and quotations from management in this announcement, as well as 111's strategic and operational plans,
contain forward-looking statements. 111 may also make written or oral forward-looking statements in its periodic reports to the U.S. Securities
and Exchange Commission, in its annual report to shareholders, in press releases and other written materials and in oral statements made
by its officers, directors or employees to third parties. Such statements are based upon management's current expectations and current
market and operating conditions and relate to events that involve known or unknown risks, uncertainties and other factors, all of which
are difficult to predict and many of which are beyond the Company's control. Forward-looking statements involve inherent risks, uncertainties
and other factors that could cause actual results to differ materially from those contained in any such statements. Potential risks and
uncertainties include, but are not limited to, uncertainties as to the Company's ability comply with extensive and evolving regulatory
requirements, its ability to compete effectively in the evolving PRC general health and wellness market, its ability to manage the growth
of its business and expansion plans, its ability to achieve or maintain profitability in the future, its ability to control the risks
associated with its pharmaceutical retail and wholesale businesses, and the Company's ability to meet the standards necessary to maintain
listing of its ADSs on the Nasdaq Global Market, including its ability to cure any non-compliance with Nasdaq's continued listing criteria.
Further information regarding these and other risks, uncertainties or factors is included in the Company's filings with the U.S. Securities
and Exchange Commission. All information provided in this press release is as of the date of this press release, and 111 does not undertake
any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required
under applicable law.
About 111, Inc.
111, Inc. (NASDAQ: YI) ("111"
or the "Company") is a leading tech-enabled healthcare platform company committed to reshaping the value chain of healthcare
industry by digitally empowering the upstream and downstream in China. The Company provides consumers with better access to pharmaceutical
products and healthcare services directly through its online retail pharmacy, 1 Pharmacy, and indirectly through its offline virtual pharmacy
network. The Company also offers online healthcare services through its internet hospital, 1 Clinic, which provides consumers with cost-effective
and convenient online consultation, electronic prescription service, and patient management service. In addition, the Company's online
platform, 1 Medicine, serves as a one-stop shop for pharmacies to source a vast selection of pharmaceutical products. With the largest
virtual pharmacy network in China, 111 enables offline pharmacies to better serve their customers with cloud-based services. 111 also
provides an omni-channel drug commercialization platform to its strategic partners, which includes services such as digital marketing,
patient education, data analytics, and pricing monitoring.
For more information on 111, please visit:
http://ir.111.com.cn/.
For more information, please contact:
111, Inc.
Investor Relations
Email: ir@111.com.cn
111, Inc.
Media Relations
Email: press@111.com.cn
Phone: +86-021-2053 6666 (China)
EXHIBIT 99.2

September 16, 2026
Board of Directors (the “Board”)
111, Inc.
(the “Company”)
10th Floor, T1, Yuzhongxin, No. 268 Yubei Road Pudong
New
Area, Shanghai, 201204, the PRC
Dear Members of the Board:
We, Dr. Gang Yu, co-founder and co-chairman
of the Company, Mr. Junling Liu, co-founder, co-chairman and chief executive officer of the Company (collectively, the “Co-Founders”)
and Huadeng Tech BioArray Ventures Ltd (the “Sponsor”, and together with the Co-Founders, “we”,
“our” or “us”) are pleased to submit this preliminary non-binding proposal to acquire all outstanding
Class A ordinary shares (the “Class A Shares”) of the Company, including Class A Shares represented by American depositary
shares (“ADSs”, each representing twenty Class A Shares), that are not currently owned by us in a going-private transaction
at a purchase price of US$0.226 per Class A Share or US$4.52 per ADS.
Our proposed purchase price represents
a premium of 29.5% to the closing price of the ADS on September 15, 2026, the last trading day prior to the date hereof and a premium
of 20% to the average closing price of the ADSs during the last 60 trading days prior to the date hereof.
As you know, the Co-Founders currently
own in aggregate approximately 1.3% of all the issued and outstanding Class A Shares and 100% of all the issued and outstanding Class
B ordinary shares, which represent approximately 41.6% of the total outstanding share capital of the Company and approximately 91.3% of
the aggregate voting power of the Company. We agree that the Company’s board of directors should appoint a special committee of
independent and disinterested directors to consider our proposed transaction and make a recommendation to the Board. We further agree
that the special committee shall retain its own independent legal and financial advisors to assist in its review of our proposed transaction.
We will not move forward with the transaction unless it is approved by such special committee.
None of the Company’s directors
who are affiliated with us will participate in the consideration of our proposal by the Company, the special committee or the special
committee’s advisors.
We currently intend that following
completion of the proposed transaction, the Company’s business will continue to be run in a manner that is generally consistent
with its current operations.
We have entered into a consortium
agreement dated as of the date hereof, pursuant to which the Co-Founders have agreed to vote all of the shares of the Company beneficially
by them in favor of the acquisition.
Given our knowledge of the Company,
we are in a position to complete the transaction in an expedited manner and to promptly enter into discussions regarding a merger agreement
with the special committee and its advisors providing for the acquisition of the Class A Shares that are not currently owned by us. We
expect that the merger agreement will provide for representations, warranties, covenants and conditions that are typical, customary and
appropriate for transactions of this type. We intend to fund the proposed transaction with equity capital from us in the form of rollover
equity in the Company by the Co-Founders and cash contribution by the Sponsor. Accordingly, our proposal would not be subject to any uncertainty
or delay with respect to any debt financing, and the proposed transaction will not be subject to a financing condition. We expect definitive
commitment(s) for the required financing, subject to terms and conditions set forth therein, to be in place when the definitive documentation
is signed with the Company.
We have engaged O’Melveny &
Myers LLP as our legal advisor for the proposed transaction.
Due to our obligations under the securities
laws, we intend to timely file a Schedule 13D with the Securities and Exchange Commission to disclose this proposal. However, we are sure
that you will agree with us that it is in all of our interests to ensure that we otherwise proceed in a strictly confidential manner,
unless otherwise required by law, until we have executed a definitive merger agreement relating to the proposed transaction or terminated
our discussions.
This letter constitutes only a preliminary
indication of our interest and does not constitute any binding commitment with respect to the transactions proposed in this letter or
any other transaction. No agreement, arrangement or understanding between us and the Company relating to any proposed transaction will
be created until such time as definitive documentation has been executed and delivered by us and the Company and all other appropriate
parties.
We believe that our proposal represents
an attractive opportunity for the Company’s shareholders to receive a significant premium to the current and recent prices of the
ADSs. We welcome the opportunity to meet with the special committee and/or its advisors to discuss our proposal.
Should you have any questions regarding
this proposal, please do not hesitate to contact us. We look forward to hearing from you.
[signatures page follows]
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Sincerely, |
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By: |
/s/ Gang
Yu |
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Name: Gang Yu |
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Sincerely, |
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By: |
/s/ Junling
Liu |
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Name: Junling Liu |
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Sincerely, |
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Huadeng Tech BioArray Ventures Ltd |
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By: |
/s/ Younan
He |
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Name: Younan He |
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Title: Director |
[Signature Page to Proposal Letter]