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Adagene Inc. Financials

ADAG
FY2025 annual
Revenue $7.7M +7332.8% YoY
Net Income -$17.6M +47.3% YoY
EPS (Diluted) -$0.30 +49.2% YoY
Free Cash Flow -$15.7M +47.3% YoY
Source SEC Filings (10-K/10-Q) Data as of Dec 31, 2025 Currency USD FYE December

Adagene Inc. (ADAG) reported $7.7M in revenue for fiscal year 2025, up 7332.8% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 8 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ADAG FY2025

Adagene’s business mechanic is a cash-funded R&D program, with losses driven more by investment scale than by a functioning revenue base.

Across the last three annual periods, operating cash burn fell from -$28.5M to -$15.7M, showing the cash cost of running the pipeline has been cut materially. With cash of $74.5M against current liabilities of $25.2M, the near-term constraint is continued burn rather than day-to-day liquidity.

In FY2025, R&D of $22.0M was nearly three times revenue of $7.7M, which means reported sales are not yet the engine paying for operations. This still behaves more like a financed development effort than a scaled commercial model, so losses mainly reflect how aggressively the company funds research.

Free cash flow of -$15.7M was almost identical to operating cash flow of -$15.7M, so the accounting loss is turning into real cash use rather than being offset by working-capital timing. Capital spending was only $17K and long-term debt just $1.1M, indicating a science-intensive, not asset-intensive, operating model.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 68 / 100
Financial Health Score 68/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Adagene Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
66
Dilution
57
R&D Intensity
95
Revenue Progress
36
Burn Trend
76
Balance Sheet
76
Altman Z-Score Distress
-2.27

Adagene Inc. scores -2.27, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($258.5M) relative to total liabilities ($42.9M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/8

Adagene Inc. passes 4 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality No Cash Backing
N/A

Adagene Inc. reported a net loss of $17.6M while operations used $15.7M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Adagene Inc. reported an operating loss of $21.4M against $463K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$7.7M
YoY+7332.8%
5Y CAGR+61.4%

Adagene Inc. generated $7.7M in revenue in fiscal year 2025. This represents an increase of 7332.8% from the prior year.

EBITDA
-$21.0M
YoY+40.4%

Adagene Inc.'s EBITDA was -$21.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 40.4% from the prior year.

Net Income
-$17.6M
YoY+47.3%

Adagene Inc. reported -$17.6M in net income in fiscal year 2025. This represents an increase of 47.3% from the prior year.

EPS (Diluted)
-$0.30
YoY+49.2%

Adagene Inc. earned -$0.30 per diluted share (EPS) in fiscal year 2025. This represents an increase of 49.2% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$15.7M
YoY+47.3%

Adagene Inc. recorded an outflow of $15.7M in free cash flow in fiscal year 2025, representing a cash shortfall after capex. This represents an increase of 47.3% from the prior year.

Cash & Debt
$74.5M
YoY-12.5%
5Y CAGR-0.2%

Adagene Inc. held $74.5M in cash against $1.1M in long-term debt as of fiscal year 2025.

Shares Outstanding
59M
YoY+0.6%

Adagene Inc. had 59M shares outstanding in fiscal year 2025. This represents an increase of 0.6% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Return on Equity
-49.8%
YoY+16.3pp

Adagene Inc.'s ROE was -49.8% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 16.3 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Operating Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for fiscal year 2025: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Capital Allocation

R&D Spending
$22.0M
YoY-23.4%
5Y CAGR-8.1%

Adagene Inc. invested $22.0M in research and development in fiscal year 2025. This represents a decrease of 23.4% from the prior year.

Capital Expenditures
$17K
YoY-49.2%
5Y CAGR-55.1%

Adagene Inc. invested $17K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 49.2% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

ADAG Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ADAG annual income statement
MetricFY25FY24FY23FY22FY21FY20FY19FY18
Revenue$7.7M+7332.8%$103K-99.4%$18.1M+94.9%$9.3M-8.7%$10.2M+1351.7%$701K+46.0%$480K-68.2%$1.5M
R&D Expenses$22.0M-23.4%$28.8M-21.4%$36.6M-55.0%$81.3M+19.4%$68.1M+103.1%$33.5M+106.9%$16.2M+0.8%$16.1M
SG&A Expenses$7.1M-2.7%$7.3M-16.1%$8.7M-27.0%$11.9M-17.8%$14.4M+40.0%$10.3M+200.0%$3.4M+24.3%$2.8M
Operating Income-$21.4M+40.4%-$36.0M-51.6%-$23.7M+71.7%-$83.9M-16.0%-$72.4M-67.7%-$43.2M-125.1%-$19.2M-10.6%-$17.3M
Interest Expense$463K-45.6%$852K-23.1%$1.1M+59.8%$693K+90.6%$364K+79.9%$202K+46.4%$138K+51.6%$91K
Income Tax-$298K-1596.9%-$18K-101.0%$1.7M+268.5%$459K-73.0%$1.7MN/AN/AN/A
Net Income-$17.6M+47.3%-$33.4M-76.4%-$18.9M+76.3%-$80.0M-9.3%-$73.2M-72.6%-$42.4M-158.0%-$16.4M-7.6%-$15.3M
EPS (Diluted)-$0.30+49.2%-$0.59-68.6%-$0.35-$0.31-$1.46-$2.67-$1.10-17.0%-$0.94

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

ADAG Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ADAG annual balance sheet
MetricFY25FY24FY23FY22FY21FY20FY19FY18
Total Assets$78.3M-12.3%$89.3M-22.9%$115.7M-24.1%$152.4M-19.6%$189.5M+124.9%$84.3M-20.4%$105.9MN/A
Current Assets$77.4M-11.9%$87.8M-22.6%$113.4M-24.0%$149.3M-19.7%$186.0M+135.1%$79.1M-23.9%$103.9MN/A
Cash & Equivalents$74.5M-12.5%$85.2M-22.5%$109.9M-23.5%$143.8M-17.6%$174.4M+132.1%$75.2M-18.8%$92.5M+476.2%$16.1M
Accounts ReceivableN/AN/AN/AN/A$3.0MN/A$480KN/A
Total Liabilities$42.9M+10.8%$38.7M-14.2%$45.2M-34.8%$69.3M+110.3%$33.0M-81.0%$173.7M+6.6%$162.9MN/A
Current Liabilities$25.2M-34.1%$38.2M+21.4%$31.5M-42.9%$55.1M+84.7%$29.8M+84.7%$16.1M+124.8%$7.2MN/A
Long-Term Debt$1.1M+172.7%$417K-96.9%$13.5M-4.3%$14.1M+372.8%$3.0M+0.9%$3.0M+95.6%$1.5MN/A
Total Equity$35.3M-30.0%$50.5M-28.4%$70.6M-15.1%$83.1M-46.9%$156.6M+275.1%-$89.4M-56.8%-$57.0M-39.0%-$41.0M
Retained Earnings-$328.8M-5.7%-$311.2M-12.0%-$277.8M-7.3%-$258.8M-44.7%-$178.8M-69.3%-$105.7M-67.0%-$63.3MN/A

Not reported in any period shown, so not listed: Inventory, Goodwill.

ADAG Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ADAG annual cash flow statement
MetricFY25FY24FY23FY22FY21FY20FY19FY18
Operating Cash Flow-$15.7M+47.3%-$29.7M-4.4%-$28.5M+41.5%-$48.6M-12.0%-$43.4M-52.2%-$28.5M-57.2%-$18.2M-27.3%-$14.3M
Capital Expenditures$17K-49.2%$34K-60.5%$85K-87.7%$691K-72.5%$2.5M+168.4%$935K+516.0%$152K-70.5%$515K
Free Cash Flow-$15.7M+47.3%-$29.7M-4.2%-$28.5M+42.1%-$49.3M-7.4%-$45.9M-55.9%-$29.5M-61.0%-$18.3M-23.9%-$14.8M
Investing Cash Flow$477K-57.0%$1.1M+1535.1%-$77K+88.7%-$686K+72.7%-$2.5M-135.5%$7.1M-71.5%$24.9M+184.2%-$29.5M
Financing Cash Flow$4.4M+17.9%$3.8M+170.2%-$5.4M-130.1%$17.8M-87.7%$145.4M+3174.3%$4.4M-93.6%$69.7M+36.5%$51.1M
Share BuybacksN/AN/AN/A$4.0M+68.4%$2.4MN/AN/AN/A

Not reported in any period shown, so not listed: Dividends Paid.

ADAG Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

ADAG annual financial ratios
MetricFY25FY24FY23FY22FY21FY20FY19FY18
Operating Margin-279.5%-34835.4%-131.0%-903.1%-711.2%-6156.5%-3993.7%-1147.1%
Net Margin-229.6%-32386.5%-104.6%-860.6%-719.2%-6048.9%-3423.4%-1010.2%
Return on Equity-49.8%+16.3pp-66.2%-39.3pp-26.9%+69.4pp-96.3%-49.5pp-46.7%N/AN/AN/A
Return on Assets-22.5%+14.9pp-37.4%-21.1pp-16.4%+36.1pp-52.5%-13.9pp-38.6%+11.7pp-50.3%-34.8pp-15.5%N/A
Current Ratio3.07+0.8x2.30-1.3x3.61+0.9x2.71-3.5x6.24+1.3x4.90-9.6x14.47N/A
Debt-to-Equity0.030.0x0.01-0.2x0.190.0x0.17+0.2x0.02N/AN/AN/A
FCF Margin-204.3%-28811.5%-157.6%-530.6%-451.3%-4203.8%-3813.6%-978.0%

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Adagene Inc.'s annual revenue?

Adagene Inc. (ADAG) reported $7.7M in total revenue for fiscal year 2025. This represents a 7332.8% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Adagene Inc.'s revenue growing?

Adagene Inc. (ADAG) revenue grew by 7332.8% year-over-year, from $103K to $7.7M in fiscal year 2025.

Is Adagene Inc. profitable?

No, Adagene Inc. (ADAG) reported a net income of -$17.6M in fiscal year 2025.

Adagene Inc. (ADAG) reported diluted earnings per share of -$0.30 for fiscal year 2025. This represents a 49.2% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Adagene Inc. (ADAG) had EBITDA of -$21.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Adagene Inc. (ADAG) had $74.5M in cash and equivalents against $1.1M in long-term debt.

Adagene Inc. (ADAG) has a return on equity of -49.8% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Adagene Inc. (ADAG) recorded an outflow of $15.7M in free cash flow during fiscal year 2025. This represents a 47.3% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Adagene Inc. (ADAG) recorded an outflow of $15.7M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Adagene Inc. (ADAG) had $78.3M in total assets as of fiscal year 2025, including both current and long-term assets.

Adagene Inc. (ADAG) invested $17K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Adagene Inc. (ADAG) invested $22.0M in research and development during fiscal year 2025.

Adagene Inc. (ADAG) had 59M shares outstanding as of fiscal year 2025.

Adagene Inc. (ADAG) had a current ratio of 3.07 as of fiscal year 2025, which is generally considered healthy.

Adagene Inc. (ADAG) had a debt-to-equity ratio of 0.03 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Adagene Inc. (ADAG) had a return on assets of -22.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2025, Adagene Inc. (ADAG) held $74.5M in cash, cash equivalents and investments, and reported an operating cash outflow of $15.7M over that year. Dividing the one by the other, the reported balance equals about 57 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Adagene Inc. (ADAG) has an Altman Z-Score of -2.27, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Adagene Inc. (ADAG) has a Piotroski F-Score of 4 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Adagene Inc. (ADAG) reported a net loss of $17.6M while operations used $15.7M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Adagene Inc. (ADAG) reported an operating loss of $21.4M against $463K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Adagene Inc. (ADAG) scores 68 out of 100 on our Financial Health Score, indicating strong standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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