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Ensysce Biosciences, Inc. (ENSC) Financials

ENSC
FY2025 annual
Revenue $5.1M -2.8% YoY
Net Income -$10.2M -27.4% YoY
EPS (Diluted) -$3.98 YoY not available
Free Cash Flow -$7.9M YoY not available
Market Cap $9.5M as of Sep 14, 2026
Price / Sales 2.1x on $4.5M revenue, trailing 12 months to June 30, 2026
Price / Earnings n/m net loss, so no earnings multiple, trailing 12 months to June 30, 2026
Price / Book n/m negative shareholder equity, so no book multiple, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Sep 14, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 13, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the ENSC SEC filings page.

Ensysce Biosciences, Inc. (ENSC) reported $5.1M in revenue for fiscal year 2025, down 2.8% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 8 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ENSC FY2025

Development-funded business: revenue is small relative to R&D, while external financing supports recurring cash consumption.

In FY2025, R&D spending exceeded revenue: $10.4M versus $5.1M, making product development the larger economic activity than reported sales. Revenue then slipped while R&D expanded, so the operating loss reflects a development-heavy cost structure rather than commercial scale absorbing those costs.

The 2025 net loss was -$10.2M and operating cash flow was -$7.8M, a relatively close pairing indicating that accounting losses are translating into cash outflows. Free cash flow was -$7.9M despite only $124K of capital expenditures, making ongoing operations—not asset building—the principal cash demand.

Equity moved from negative to positive, but the current ratio fell from 2.4x to 1.6x; improved net worth therefore did not mean steadily looser short-term finances. Reported liquidity equaled 6.6 months of annual outflow, while financing cash flow supplied $8.7M, describing a business funded externally while it continues development spending.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 59 / 100
Financial Health Score 59/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Ensysce Biosciences, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
23

Ensysce Biosciences, Inc. held $4.3M in cash, cash equivalents and investments at the end of fiscal year 2025, and its operations used $7.8M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and Ensysce Biosciences, Inc. scores 23/100 among other emerging companies.

Dilution
44

Ensysce Biosciences, Inc. had 9M shares outstanding at the end of fiscal year 2025. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and Ensysce Biosciences, Inc. scores 44/100 among other emerging companies.

R&D Intensity
89

Ensysce Biosciences, Inc. spent $10.4M on research and development in fiscal year 2025, which was 67.8% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and Ensysce Biosciences, Inc. scores 89/100 among other emerging companies.

Revenue Progress
79

Ensysce Biosciences, Inc. reported revenue of $5.1M in fiscal year 2025, against $5.2M in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and Ensysce Biosciences, Inc. scores 79/100 among other emerging companies.

Burn Trend
60

Ensysce Biosciences, Inc.'s operations used $7.8M of cash in fiscal year 2025, against $7.5M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and Ensysce Biosciences, Inc. scores 60/100 among other emerging companies.

Balance Sheet
57

Ensysce Biosciences, Inc.'s cash, cash equivalents and investments came to $4.3M at the end of fiscal year 2025, against $4.6M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and Ensysce Biosciences, Inc. scores 57/100 among other emerging companies.

Altman Z-Score Distress
-28.43

Ensysce Biosciences, Inc. scores -28.43, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($9.5M) relative to total liabilities ($4.6M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
2/7

Ensysce Biosciences, Inc. passes 2 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

Ensysce Biosciences, Inc. reported a net loss of $10.2M while operations used $7.8M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Interest Coverage At Risk
N/A

Ensysce Biosciences, Inc. reported an operating loss of $10.2M against $6K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.

Key Financial Metrics

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Earnings & Revenue

Revenue
$1.2M
YoY-15.1%
QoQ+21.2%
5Y CAGR+21.2%

Ensysce Biosciences, Inc. generated $1.2M in revenue in Q2 2026. This represents a decrease of 15.1% from the same quarter a year earlier. Against the prior quarter it is up 21.2%.

EBITDA
-$2.6M
YoY-46.8%
QoQ+27.7%

Ensysce Biosciences, Inc.'s EBITDA was -$2.6M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 46.8% from the same quarter a year earlier. Against the prior quarter it is up 27.7%.

Net Income
-$2.6M
YoY-48.3%
QoQ+27.7%

Ensysce Biosciences, Inc. reported -$2.6M in net income in Q2 2026. This represents a decrease of 48.3% from the same quarter a year earlier. Against the prior quarter it is up 27.7%.

EPS (Diluted)
-$0.20

Ensysce Biosciences, Inc. earned -$0.20 per diluted share (EPS) in Q2 2026.

Cash & Balance Sheet

Cash & Debt
$677K
YoY-69.4%
QoQ-9.2%
5Y CAGR-39.0%

Ensysce Biosciences, Inc. held $677K in cash as of Q2 2026; long-term debt is not reported for that period.

Shares Outstanding
19M
5Y CAGR-4.3%

Ensysce Biosciences, Inc. had 19M shares outstanding in Q2 2026.

Free Cash Flow

Not reported for Q2 2026.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin

Not shown for Q2 2026: the reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Return on Equity

Not reported for Q2 2026.

Capital Allocation

R&D Spending
$2.5M
YoY+28.5%
QoQ-26.1%
5Y CAGR+39.8%

Ensysce Biosciences, Inc. invested $2.5M in research and development in Q2 2026. This represents an increase of 28.5% from the same quarter a year earlier. Against the prior quarter it is down 26.1%.

Share Buybacks

Not reported for Q2 2026.

Capital Expenditures

Not reported for Q2 2026.

ENSC Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ENSC quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Revenue$1.2M-15.1%$961K-27.2%$1.9M+44.4%$493K-85.6%$1.4M+654.4%$1.3M+331.7%$1.3M+153.1%$3.4M+685.3%
R&D Expenses$2.5M+28.5%$3.3M+77.5%$3.6M-5.0%$3.0M+74.8%$1.9M+103.1%$1.9M+142.1%$3.8M+70.3%$1.7M-11.7%
SG&A Expenses$1.3M+5.9%$1.2M-16.1%$1.1M-2.4%$1.3M+18.1%$1.2M+0.7%$1.4M+2.3%$1.1M-25.1%$1.1M-11.8%
Operating Income-$2.6M-47.2%-$3.6M-81.1%-$2.8M+22.2%-$3.7M-680.2%-$1.8M+10.5%-$2.0M-6.8%-$3.6M-13.3%$645K+123.8%
EBITDA-$2.6M-46.8%-$3.6M-80.7%-$2.8M+22.4%-$3.7M-680.2%-$1.8M+10.5%-$2.0M-6.8%-$3.6M$645K
Interest Expense$320$834-8.3%$2K+100.2%$3K-21.0%$0-100.0%$909-99.9%-$1.2M-460.6%$4K-46.9%
Net Income-$2.6M-48.3%-$3.6M-82.8%-$2.8M+22.3%-$3.7M-663.5%-$1.7M+11.9%-$1.9M+37.6%-$3.6M-1.7%$662K+124.6%
EPS (Basic)-$0.20+74.7%-$0.52+62.6%-$0.56+94.9%-$1.29-229.0%-$0.79+76.4%-$1.39+83.1%-$10.88+83.8%$1.00+214.9%
EPS (Diluted)-$0.20-$0.52-$0.56-$1.29-$0.79-$1.39-$10.88$1.00
Diluted Shares (Avg)13M7MN/A3M2M1MN/A659,361

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Income Tax.

ENSC Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ENSC quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$3.0M-46.9%$2.2M-53.0%$7.5M+33.1%$3.2M-66.1%$5.6M+99.4%$4.6M-9.1%$5.6M+106.7%$9.4M+191.6%
Current Assets$2.8M-46.1%$2.0M-54.4%$7.2M+35.6%$2.9M-67.8%$5.3M+114.7%$4.4M-6.3%$5.3M+133.5%$9.1M+229.6%
Cash & Equivalents$677K-69.4%$745K-75.6%$4.3M+23.1%$1.7M-59.7%$2.2M+112.0%$3.1M-10.3%$3.5M+211.7%$4.2M+183.6%
Short-Term Investments$0$0$0$0$0$0$0$0
Long-Term Investments$0$0$0$0$0$0$0$0
Total Liabilities$4.1M+61.8%$2.8M+50.0%$4.6M+106.0%$2.3M-17.8%$2.5M+91.0%$1.9M+14.4%$2.2M-34.0%$2.8M+36.1%
Current Liabilities$4.1M+61.9%$2.8M+61.1%$4.6M+106.9%$2.3M-17.7%$2.5M+92.3%$1.8M+7.6%$2.2M-33.8%$2.8M+38.0%
Non-Current Liabilities$0-100.0%$0-100.0%$0-100.0%$35-98.9%$1K-89.3%$130K+646.7%$10K-61.7%$3K-89.5%
Total Equity-$782K-123.1%-$340K-111.2%$3.2M-13.3%$1.2M-82.6%$3.4M+87.5%$3.0M-18.7%$3.7M+1248.6%$6.9M+365.2%
Retained Earnings-$145.8M-9.5%-$143.3M-9.0%-$139.7M-7.9%-$137.0M-8.7%-$133.2M-5.2%-$131.5M-5.5%-$129.5M-6.6%-$126.0M-6.7%

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

ENSC Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ENSC quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow-$2.0M+27.5%-$3.5M-105.0%-$1.5M-99.7%-$1.9M-82.9%-$2.7M-17.2%-$1.7M+49.9%-$764K+57.6%-$1.0M+54.9%
Depreciation & Amortization$7K$7K$7K$0$0$0$0$0
Stock-Based CompensationN/A$9K-46.2%N/AN/AN/A$16K-51.1%N/AN/A
Capital ExpendituresN/AN/A$0N/AN/AN/AN/AN/A
Free Cash FlowN/AN/A-$1.5MN/AN/AN/AN/AN/A
Investing Cash FlowN/AN/A$0N/AN/AN/AN/AN/A
Financing Cash Flow$1.9M+1.5%-$64K-105.1%$4.2M+3598.0%$1.5M-64.9%$1.9M+3742.5%$1.3M-77.9%$113K-92.3%$4.1M+4131.7%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

ENSC Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ENSC quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Margin-221.3%-370.7%-147.8%-758.7%-127.6%-149.1%-274.3%18.9%
Net Margin-220.8%-370.1%-147.0%-756.3%-126.4%-147.4%-273.4%19.4%
Return on EquityN/AN/A-86.1%+10.0pp-309.9%-319.5pp-51.1%+57.7pp-63.8%+19.3pp-96.1%9.6%+190.8pp
Return on Assets-86.9%-55.8pp-164.1%-121.9pp-37.1%+26.5pp-117.3%-124.3pp-31.1%+39.3pp-42.2%+19.2pp-63.7%+65.7pp7.0%+90.6pp
Current Ratio0.70-1.4x0.71-1.8x1.59-0.8x1.27-2.0x2.10+0.2x2.50-0.4x2.42+1.7x3.24+1.9x
Debt-to-EquityN/AN/A1.42+0.8x1.92+1.5x0.740.0x0.62+0.2x0.600.41-1.0x
Asset Turnover0.39+0.1x0.44+0.2x0.250.0x0.16-0.2x0.25+0.2x0.29+0.2x0.230.0x0.36+0.2x
FCF MarginN/AN/A-81.1%N/AN/AN/AN/AN/A

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Ensysce Biosciences, Inc. ENSC FY2025 $5.1M -$10.2M N/A $9.5M 59/100
Artelo Biosciences, Inc. ARTL FY2025 N/A -$12.9M N/A $3.0M
Silo Pharma, Inc. SILO FY2025 $72K -$4.2M N/A $3.7M
Polyrizon Ltd. PLRZ FY2025 N/A -$3.3M N/A $26.2M
TITAN PHARMACEUTICAL INC TTNP FY2024 N/A -$4.7M N/A $6.1M

Frequently Asked Questions

What is Ensysce Biosciences, Inc.'s annual revenue?

Ensysce Biosciences, Inc. (ENSC) reported $5.1M in total revenue for fiscal year 2025. This represents a -2.8% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Ensysce Biosciences, Inc.'s revenue growing?

Ensysce Biosciences, Inc. (ENSC) revenue declined by 2.8% year-over-year, from $5.2M to $5.1M in fiscal year 2025.

Is Ensysce Biosciences, Inc. profitable?

No, Ensysce Biosciences, Inc. (ENSC) reported a net income of -$10.2M in fiscal year 2025.

Ensysce Biosciences, Inc. (ENSC) reported diluted earnings per share of -$3.98 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Ensysce Biosciences, Inc. (ENSC) had EBITDA of -$10.2M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Ensysce Biosciences, Inc. (ENSC) has a return on equity of -316.7% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Ensysce Biosciences, Inc. (ENSC) recorded an outflow of $7.9M in free cash flow during fiscal year 2025. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Ensysce Biosciences, Inc. (ENSC) recorded an outflow of $7.8M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

Ensysce Biosciences, Inc. (ENSC) had $7.5M in total assets as of fiscal year 2025, including both current and long-term assets.

Ensysce Biosciences, Inc. (ENSC) invested $124K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Ensysce Biosciences, Inc. (ENSC) invested $10.4M in research and development during fiscal year 2025.

Ensysce Biosciences, Inc. (ENSC) had 9M shares outstanding as of fiscal year 2025.

Ensysce Biosciences, Inc. (ENSC) had a current ratio of 1.59 as of fiscal year 2025, which is generally considered healthy.

Ensysce Biosciences, Inc. (ENSC) had a debt-to-equity ratio of 1.42 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Ensysce Biosciences, Inc. (ENSC) had a return on assets of -136.5% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Ensysce Biosciences, Inc. (ENSC) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (trailing 12 months to June 30, 2026). The market capitalization is $9.5M as of Sep 14, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Ensysce Biosciences, Inc. (ENSC) trades at 2.1x sales, its market capitalization divided by revenue of $4.5M revenue, trailing 12 months to June 30, 2026. The market capitalization is $9.5M as of Sep 14, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, Ensysce Biosciences, Inc. (ENSC) held $4.3M in cash, cash equivalents and investments, and reported an operating cash outflow of $7.8M over that year. Dividing the one by the other, the reported balance equals about 7 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Ensysce Biosciences, Inc. (ENSC) has an Altman Z-Score of -28.43, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Ensysce Biosciences, Inc. (ENSC) has a Piotroski F-Score of 2 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Ensysce Biosciences, Inc. (ENSC) reported a net loss of $10.2M while operations used $7.8M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Ensysce Biosciences, Inc. (ENSC) reported an operating loss of $10.2M against $6K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Ensysce Biosciences, Inc. (ENSC) scores 59 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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