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Iteos Therapeutics, Inc. Financials

ITOS
Source SEC Filings (10-K/10-Q) Updated Jun 30, 2025 Currency USD FYE December

This page shows Iteos Therapeutics, Inc. (ITOS) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 60 / 100
Financial Profile 60/100

Based on FY2024 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Iteos Therapeutics, Inc. has an operating margin of -455.8%, meaning the company retains $-456 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is up from -1199.7% the prior year.

Growth
100

Iteos Therapeutics, Inc.'s revenue surged 177.9% year-over-year to $35.0M, reflecting rapid business expansion. This strong growth earns a score of 100/100.

Leverage
100

Iteos Therapeutics, Inc. carries a low D/E ratio of 0.16, meaning only $0.16 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 100/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
100

With a current ratio of 12.62, Iteos Therapeutics, Inc. holds $12.62 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.

Cash Flow
0

While Iteos Therapeutics, Inc. generated -$98.2M in operating cash flow, capex of $1.6M consumed most of it, leaving -$99.8M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Piotroski F-Score Weak
2/9

Iteos Therapeutics, Inc. passes 2 of 9 financial strength tests. 1 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality Low Quality
0.73x

For every $1 of reported earnings, Iteos Therapeutics, Inc. generates $0.73 in operating cash flow (-$98.2M OCF vs -$134.4M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Key Financial Metrics

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Revenue
$35.0M
YoY+177.9%

Iteos Therapeutics, Inc. generated $35.0M in revenue in fiscal year 2024. This represents an increase of 177.9% from the prior year.

EBITDA
-$158.3M
YoY-5.4%

Iteos Therapeutics, Inc.'s EBITDA was -$158.3M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 5.4% from the prior year.

Free Cash Flow
-$99.8M
YoY+6.5%

Iteos Therapeutics, Inc. generated -$99.8M in free cash flow in fiscal year 2024, representing cash available after capex. This represents an increase of 6.5% from the prior year.

Net Income
-$134.4M
YoY-19.3%

Iteos Therapeutics, Inc. reported -$134.4M in net income in fiscal year 2024. This represents a decrease of 19.3% from the prior year.

EPS (Diluted)
$-3.32
YoY-5.4%

Iteos Therapeutics, Inc. earned $-3.32 per diluted share (EPS) in fiscal year 2024. This represents a decrease of 5.4% from the prior year.

Cash & Debt
$142.1M
YoY-43.4%
5Y CAGR+48.2%

Iteos Therapeutics, Inc. held $142.1M in cash against $0 in long-term debt as of fiscal year 2024.

Dividends Per Share
N/A
Shares Outstanding
37M
YoY+1.9%

Iteos Therapeutics, Inc. had 37M shares outstanding in fiscal year 2024. This represents an increase of 1.9% from the prior year.

Gross Margin
N/A
Operating Margin
-455.8%
YoY+743.9pp

Iteos Therapeutics, Inc.'s operating margin was -455.8% in fiscal year 2024, reflecting core business profitability. This is up 743.9 percentage points from the prior year.

Net Margin
-384.0%
YoY+510.3pp

Iteos Therapeutics, Inc.'s net profit margin was -384.0% in fiscal year 2024, showing the share of revenue converted to profit. This is up 510.3 percentage points from the prior year.

Return on Equity
N/A
R&D Spending
$145.4M
YoY+28.4%
5Y CAGR+49.9%

Iteos Therapeutics, Inc. invested $145.4M in research and development in fiscal year 2024. This represents an increase of 28.4% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$1.6M
YoY-44.9%
5Y CAGR+17.8%

Iteos Therapeutics, Inc. invested $1.6M in capex in fiscal year 2024, funding long-term assets and infrastructure. This represents a decrease of 44.9% from the prior year.

ITOS Income Statement

Metric Q2'25 Q2'24 Q3'24 Q1'24 Q4'23 Q3'23 Q2'23 Q1'23
Revenue $0 $0 $0 $0 $0 $0 $0-100.0% $12.6M
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $57.3M+52.6% $37.5M+2.3% $36.7M+6.2% $34.5M+23.9% $27.9M-9.0% $30.6M+5.0% $29.2M+14.0% $25.6M
SG&A Expenses $10.2M-13.8% $11.8M-2.5% $12.1M-4.7% $12.7M+2.5% $12.4M-2.0% $12.6M-5.9% $13.4M+12.6% $11.9M
Operating Income -$83.8M-69.9% -$49.3M-1.1% -$48.8M-3.3% -$47.2M-17.3% -$40.3M+7.0% -$43.3M-1.5% -$42.6M-71.0% -$24.9M
Interest Expense N/A N/A N/A N/A N/A N/A N/A N/A
Income Tax $1.7M-77.3% $7.4M+227.9% $2.2M+1.3% $2.2M-6.3% $2.4M+300.0% -$1.2M-195.9% $1.2M+2.8% $1.2M
Net Income -$78.7M-80.1% -$43.7M+3.6% -$45.4M-18.7% -$38.2M-25.1% -$30.6M+5.2% -$32.2M+6.0% -$34.3M-120.6% -$15.6M
EPS (Diluted) $-1.81-77.5% $-1.02+2.9% $-1.05+1.9% $-1.07-25.9% $-0.85+5.6% $-0.90+6.2% $-0.96-118.2% $-0.44

ITOS Balance Sheet

Metric Q2'25 Q2'24 Q3'24 Q1'24 Q4'23 Q3'23 Q2'23 Q1'23
Total Assets $623.1M-9.3% $687.0M-5.0% $723.1M+14.8% $629.8M-5.7% $667.6M-1.5% $677.6M-3.7% $703.7M-3.4% $728.3M
Current Assets $529.0M+3.8% $509.5M-6.5% $544.9M+13.4% $480.4M-12.8% $550.7M-11.1% $619.1M+0.7% $614.5M-0.1% $615.4M
Cash & Equivalents $207.8M+46.2% $142.1M+14.9% $123.7M-15.6% $146.6M-41.6% $251.2M+23.0% $204.1M-5.6% $216.2M-4.1% $225.4M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $129.3M+33.7% $96.7M+5.8% $91.4M+3.2% $88.6M-4.1% $92.4M+16.3% $79.4M-1.0% $80.2M+5.4% $76.1M
Current Liabilities $70.3M+74.1% $40.4M+9.6% $36.8M+3.5% $35.6M-11.1% $40.0M+41.8% $28.2M-6.0% $30.0M+13.9% $26.4M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $493.8M-16.3% $590.3M-6.6% $631.7M+16.7% $541.2M-5.9% $575.2M-3.9% $598.3M-4.1% $623.5M-4.4% $652.3M
Retained Earnings -$123.1M-1158.8% -$9.8M-128.8% $33.9M+139.3% -$86.4M-169.3% $124.6M-19.7% $155.2M-17.2% $187.4M-15.5% $221.7M

ITOS Cash Flow Statement

Metric Q2'25 Q2'24 Q3'24 Q1'24 Q4'23 Q3'23 Q2'23 Q1'23
Operating Cash Flow -$42.4M-872.2% $5.5M+114.7% -$37.4M-15.3% -$32.4M-135.4% -$13.8M+59.4% -$33.9M-14.7% -$29.5M-11.3% -$26.6M
Capital Expenditures $283K+86.2% $152K+61.7% $94K-90.1% $945K-32.3% $1.4M+85.9% $751K+7.3% $700K+488.2% $119K
Free Cash Flow -$42.7M-899.4% $5.3M+114.3% -$37.4M-12.3% -$33.3M-119.9% -$15.2M+56.2% -$34.6M-14.5% -$30.2M-13.4% -$26.7M
Investing Cash Flow $87.0M+538.6% $13.6M+114.9% -$91.5M-31.5% -$69.6M-213.1% $61.6M+171.3% $22.7M+12.9% $20.1M+163.4% -$31.7M
Financing Cash Flow $4.5M+1476.5% $285K+164.5% -$442K-2109.1% $22K-92.8% $307K+2970.0% $10K-95.4% $218K-62.3% $578K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

ITOS Financial Ratios

Metric Q2'25 Q2'24 Q3'24 Q1'24 Q4'23 Q3'23 Q2'23 Q1'23
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin N/A -40.5% N/A N/A N/A N/A N/A -197.9%
Net Margin N/A -20.4% N/A N/A N/A N/A N/A -123.5%
Return on Equity N/A N/A N/A N/A N/A N/A N/A N/A
Return on Assets -12.6%-6.3pp -6.4%-0.1pp -6.3%-0.2pp -6.1%-1.5pp -4.6%+0.2pp -4.8%+0.1pp -4.9%-2.7pp -2.1%
Current Ratio 7.53-5.1 12.62-2.2 14.80+1.3 13.51-0.3 13.76-8.2 21.94+1.5 20.47-2.9 23.35
Debt-to-Equity 0.26+0.1 0.16+0.0 0.14-0.0 0.160.0 0.16+0.0 0.130.0 0.13+0.0 0.12
FCF Margin N/A -98.2% N/A N/A N/A N/A N/A -211.8%

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Frequently Asked Questions

What is Iteos Therapeutics, Inc.'s annual revenue?

Iteos Therapeutics, Inc. (ITOS) reported $35.0M in total revenue for fiscal year 2024. This represents a 177.9% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Iteos Therapeutics, Inc.'s revenue growing?

Iteos Therapeutics, Inc. (ITOS) revenue grew by 177.9% year-over-year, from $12.6M to $35.0M in fiscal year 2024.

Is Iteos Therapeutics, Inc. profitable?

No, Iteos Therapeutics, Inc. (ITOS) reported a net income of -$134.4M in fiscal year 2024, with a net profit margin of -384.0%.

What is Iteos Therapeutics, Inc.'s earnings per share (EPS)?

Iteos Therapeutics, Inc. (ITOS) reported diluted earnings per share of $-3.32 for fiscal year 2024. This represents a -5.4% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

What is Iteos Therapeutics, Inc.'s EBITDA?

Iteos Therapeutics, Inc. (ITOS) had EBITDA of -$158.3M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization.

What is Iteos Therapeutics, Inc.'s operating margin?

Iteos Therapeutics, Inc. (ITOS) had an operating margin of -455.8% in fiscal year 2024, reflecting the profitability of core business operations before interest and taxes.

What is Iteos Therapeutics, Inc.'s net profit margin?

Iteos Therapeutics, Inc. (ITOS) had a net profit margin of -384.0% in fiscal year 2024, representing the share of revenue converted into profit after all expenses.

What is Iteos Therapeutics, Inc.'s free cash flow?

Iteos Therapeutics, Inc. (ITOS) generated -$99.8M in free cash flow during fiscal year 2024. This represents a 6.5% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

What is Iteos Therapeutics, Inc.'s operating cash flow?

Iteos Therapeutics, Inc. (ITOS) generated -$98.2M in operating cash flow during fiscal year 2024, representing cash generated from core business activities.

What are Iteos Therapeutics, Inc.'s total assets?

Iteos Therapeutics, Inc. (ITOS) had $687.0M in total assets as of fiscal year 2024, including both current and long-term assets.

What are Iteos Therapeutics, Inc.'s capital expenditures?

Iteos Therapeutics, Inc. (ITOS) invested $1.6M in capital expenditures during fiscal year 2024, funding long-term assets and infrastructure.

How much does Iteos Therapeutics, Inc. spend on research and development?

Iteos Therapeutics, Inc. (ITOS) invested $145.4M in research and development during fiscal year 2024.

How many shares does Iteos Therapeutics, Inc. have outstanding?

Iteos Therapeutics, Inc. (ITOS) had 37M shares outstanding as of fiscal year 2024.

What is Iteos Therapeutics, Inc.'s current ratio?

Iteos Therapeutics, Inc. (ITOS) had a current ratio of 12.62 as of fiscal year 2024, which is generally considered healthy.

What is Iteos Therapeutics, Inc.'s debt-to-equity ratio?

Iteos Therapeutics, Inc. (ITOS) had a debt-to-equity ratio of 0.16 as of fiscal year 2024, measuring the company's financial leverage by comparing total debt to shareholder equity.

What is Iteos Therapeutics, Inc.'s return on assets (ROA)?

Iteos Therapeutics, Inc. (ITOS) had a return on assets of -19.6% for fiscal year 2024, measuring how efficiently the company uses its assets to generate profit.

What is Iteos Therapeutics, Inc.'s cash runway?

Based on fiscal year 2024 data, Iteos Therapeutics, Inc. (ITOS) had $142.1M in cash against an annual operating cash burn of $98.2M. This gives an estimated cash runway of approximately 17 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

What is Iteos Therapeutics, Inc.'s Piotroski F-Score?

Iteos Therapeutics, Inc. (ITOS) has a Piotroski F-Score of 2 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Are Iteos Therapeutics, Inc.'s earnings high quality?

Iteos Therapeutics, Inc. (ITOS) has an earnings quality ratio of 0.73x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

How financially healthy is Iteos Therapeutics, Inc.?

Iteos Therapeutics, Inc. (ITOS) scores 60 out of 100 on our Financial Profile, indicating moderate overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.