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Entrada Therapeutics, Inc. Financials

TRDA
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Entrada Therapeutics, Inc. (TRDA) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 33 / 100
Financial Profile 33/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Entrada Therapeutics, Inc. has an operating margin of -621.1%, meaning the company retains $-621 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is down from 22.3% the prior year.

Growth
0

Entrada Therapeutics, Inc.'s revenue declined 87.9% year-over-year, from $210.8M to $25.4M. This contraction results in a growth score of 0/100.

Leverage
97

Entrada Therapeutics, Inc. carries a low D/E ratio of 0.23, meaning only $0.23 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 97/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
100

With a current ratio of 12.53, Entrada Therapeutics, Inc. holds $12.53 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 100/100.

Cash Flow
0

While Entrada Therapeutics, Inc. generated -$128.5M in operating cash flow, capex of $1.0M consumed most of it, leaving -$129.6M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Entrada Therapeutics, Inc. generates a -47.0% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is down from 15.3% the prior year.

Piotroski F-Score Weak
2/9

Entrada Therapeutics, Inc. passes 2 of 9 financial strength tests. 1 of 4 profitability signals pass, 1 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality Low Quality
0.89x

For every $1 of reported earnings, Entrada Therapeutics, Inc. generates $0.89 in operating cash flow (-$128.5M OCF vs -$143.8M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Key Financial Metrics

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Earnings & Revenue

Revenue
$25.4M
YoY-87.9%

Entrada Therapeutics, Inc. generated $25.4M in revenue in fiscal year 2025. This represents a decrease of 87.9% from the prior year.

EBITDA
-$153.8M
YoY-402.9%

Entrada Therapeutics, Inc.'s EBITDA was -$153.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 402.9% from the prior year.

Net Income
-$143.8M
YoY-319.0%

Entrada Therapeutics, Inc. reported -$143.8M in net income in fiscal year 2025. This represents a decrease of 319.0% from the prior year.

EPS (Diluted)
$-3.47
YoY-306.5%

Entrada Therapeutics, Inc. earned $-3.47 per diluted share (EPS) in fiscal year 2025. This represents a decrease of 306.5% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$129.6M
YoY-189.7%

Entrada Therapeutics, Inc. generated -$129.6M in free cash flow in fiscal year 2025, representing cash available after capex. This represents a decrease of 189.7% from the prior year.

Cash & Debt
$90.4M
YoY-10.7%
5Y CAGR+18.3%

Entrada Therapeutics, Inc. held $90.4M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
38M
YoY+1.9%

Entrada Therapeutics, Inc. had 38M shares outstanding in fiscal year 2025. This represents an increase of 1.9% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
-621.1%
YoY-643.4pp

Entrada Therapeutics, Inc.'s operating margin was -621.1% in fiscal year 2025, reflecting core business profitability. This is down 643.4 percentage points from the prior year.

Net Margin
-565.5%
YoY-596.6pp

Entrada Therapeutics, Inc.'s net profit margin was -565.5% in fiscal year 2025, showing the share of revenue converted to profit. This is down 596.6 percentage points from the prior year.

Return on Equity
-47.0%
YoY-62.3pp

Entrada Therapeutics, Inc.'s ROE was -47.0% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 62.3 percentage points from the prior year.

Capital Allocation

R&D Spending
$142.3M
YoY+13.5%
5Y CAGR+46.5%

Entrada Therapeutics, Inc. invested $142.3M in research and development in fiscal year 2025. This represents an increase of 13.5% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$1.0M
YoY-67.0%
5Y CAGR-14.8%

Entrada Therapeutics, Inc. invested $1.0M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 67.0% from the prior year.

TRDA Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $1.3M-19.5% $1.6M-17.2% $1.9M-90.5% $20.6M-45.0% $37.4M+91.1% $19.6M-79.3% $94.7M+60.2% $59.1M
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $34.0M-11.5% $38.4M+1.3% $37.9M+18.1% $32.1M-4.0% $33.4M+6.9% $31.3M-2.4% $32.0M+12.0% $28.6M
SG&A Expenses $9.6M-7.3% $10.3M-5.7% $10.9M+6.3% $10.3M+4.2% $9.9M-1.1% $10.0M+8.0% $9.2M-1.7% $9.4M
Operating Income -$42.2M+10.3% -$47.1M-0.4% -$46.8M-115.0% -$21.8M-271.4% -$5.9M+72.9% -$21.7M-140.5% $53.4M+153.0% $21.1M
Interest Expense N/A N/A N/A N/A N/A N/A N/A N/A
Income Tax $92K-85.9% $654K+267.4% $178K $0+100.0% -$1.9M-0.5% -$1.9M-167.4% $2.8M+50.6% $1.8M
Net Income -$39.2M+11.3% -$44.1M-2.4% -$43.1M-148.4% -$17.3M-1634.0% $1.1M+108.1% -$14.0M-125.5% $55.0M+134.2% $23.5M
EPS (Diluted) N/A $-1.06-1.9% $-1.04-147.6% $-0.42 N/A $-0.35-122.6% $1.55+127.9% $0.68

TRDA Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $377.4M-8.6% $412.9M-8.0% $448.8M-7.7% $486.5M-7.6% $526.3M-5.1% $554.6M-4.7% $582.0M+13.9% $510.8M
Current Assets $306.3M-9.5% $338.3M-8.4% $369.1M-8.4% $403.2M-8.4% $440.0M-5.4% $465.3M-4.9% $489.5M+18.2% $414.2M
Cash & Equivalents $90.4M-3.1% $93.3M+28.7% $72.5M+6.8% $67.8M-33.0% $101.2M+29.7% $78.0M-57.9% $185.3M+170.7% $68.4M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $71.2M-1.3% $72.2M+4.2% $69.3M+0.1% $69.2M-29.1% $97.6M-26.1% $132.1M-13.1% $152.0M-37.0% $241.5M
Current Liabilities $24.5M+1.8% $24.0M+21.3% $19.8M+7.4% $18.4M-53.3% $39.5M-44.1% $70.6M-17.7% $85.8M-50.7% $173.9M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $306.1M-10.2% $340.7M-10.2% $379.5M-9.0% $417.3M-2.7% $428.7M+1.5% $422.4M-1.7% $429.9M+59.6% $269.4M
Retained Earnings -$273.1M-16.7% -$233.9M-23.3% -$189.8M-29.4% -$146.7M-13.4% -$129.3M+0.9% -$130.5M-12.1% -$116.4M+32.1% -$171.5M

TRDA Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$32.2M-13.7% -$28.3M+4.0% -$29.5M+23.4% -$38.5M-21.8% -$31.6M-30.2% -$24.3M-160.9% $39.8M+256.1% -$25.5M
Capital Expenditures -$207K-21.1% -$171K-162.2% $275K-76.0% $1.1M+80.2% $635K-0.6% $639K-38.9% $1.0M+24.8% $838K
Free Cash Flow -$32.4M-13.8% -$28.5M+4.3% -$29.8M+24.9% -$39.7M-23.0% -$32.2M-29.5% -$24.9M-164.2% $38.8M+247.2% -$26.4M
Investing Cash Flow $29.1M-40.7% $49.1M+45.3% $33.8M+606.6% $4.8M-91.0% $53.4M+164.4% -$82.9M-240.1% -$24.4M-193.3% $26.1M
Financing Cash Flow $192K+2300.0% $8K-97.6% $337K-3.7% $350K-75.0% $1.4M+12845.5% -$11K-100.0% $101.4M+49107.3% $206K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

TRDA Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin -3249.3%-334.1pp -2915.2%-512.7pp -2402.5%-2296.5pp -106.0%-90.3pp -15.7%+95.0pp -110.7%-167.1pp 56.4%+20.7pp 35.7%
Net Margin -3014.9%-280.5pp -2734.4%-524.0pp -2210.4%-2126.0pp -84.4%-87.4pp 3.0%+74.7pp -71.7%-129.8pp 58.1%+18.4pp 39.7%
Return on Equity -12.8%+0.2pp -13.0%-1.6pp -11.4%-7.2pp -4.2%-4.4pp 0.3%+3.6pp -3.3%-16.1pp 12.8%+4.1pp 8.7%
Return on Assets -10.4%+0.3pp -10.7%-1.1pp -9.6%-6.0pp -3.6%-3.8pp 0.2%+2.7pp -2.5%-12.0pp 9.5%+4.9pp 4.6%
Current Ratio 12.53-1.6 14.08-4.6 18.64-3.2 21.88+10.7 11.15+4.6 6.59+0.9 5.70+3.3 2.38
Debt-to-Equity 0.23+0.0 0.21+0.0 0.18+0.0 0.17-0.1 0.23-0.1 0.31-0.0 0.35-0.5 0.90
FCF Margin -2495.0%-730.2pp -1764.8%-238.4pp -1526.4%-1333.5pp -192.9%-106.7pp -86.2%+41.0pp -127.3%-168.2pp 41.0%+85.5pp -44.6%

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Frequently Asked Questions

Entrada Therapeutics, Inc. (TRDA) reported $25.4M in total revenue for fiscal year 2025. This represents a -87.9% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Entrada Therapeutics, Inc. (TRDA) revenue declined by 87.9% year-over-year, from $210.8M to $25.4M in fiscal year 2025.

No, Entrada Therapeutics, Inc. (TRDA) reported a net income of -$143.8M in fiscal year 2025, with a net profit margin of -565.5%.

Entrada Therapeutics, Inc. (TRDA) reported diluted earnings per share of $-3.47 for fiscal year 2025. This represents a -306.5% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Entrada Therapeutics, Inc. (TRDA) had EBITDA of -$153.8M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Entrada Therapeutics, Inc. (TRDA) had an operating margin of -621.1% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Entrada Therapeutics, Inc. (TRDA) had a net profit margin of -565.5% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Entrada Therapeutics, Inc. (TRDA) has a return on equity of -47.0% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Entrada Therapeutics, Inc. (TRDA) generated -$129.6M in free cash flow during fiscal year 2025. This represents a -189.7% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Entrada Therapeutics, Inc. (TRDA) generated -$128.5M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Entrada Therapeutics, Inc. (TRDA) had $377.4M in total assets as of fiscal year 2025, including both current and long-term assets.

Entrada Therapeutics, Inc. (TRDA) invested $1.0M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Entrada Therapeutics, Inc. (TRDA) invested $142.3M in research and development during fiscal year 2025.

Entrada Therapeutics, Inc. (TRDA) had 38M shares outstanding as of fiscal year 2025.

Entrada Therapeutics, Inc. (TRDA) had a current ratio of 12.53 as of fiscal year 2025, which is generally considered healthy.

Entrada Therapeutics, Inc. (TRDA) had a debt-to-equity ratio of 0.23 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Entrada Therapeutics, Inc. (TRDA) had a return on assets of -38.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Entrada Therapeutics, Inc. (TRDA) had $90.4M in cash against an annual operating cash burn of $128.5M. This gives an estimated cash runway of approximately 8 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Entrada Therapeutics, Inc. (TRDA) has a Piotroski F-Score of 2 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Entrada Therapeutics, Inc. (TRDA) has an earnings quality ratio of 0.89x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Entrada Therapeutics, Inc. (TRDA) scores 33 out of 100 on our Financial Profile, indicating weak overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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