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Zai Lab Limited Financials

ZLAB
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Zai Lab Limited (ZLAB) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 11 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 32 / 100
Financial Profile 32/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
0

Zai Lab Limited has an operating margin of -49.9%, meaning the company retains $-50 of operating profit per $100 of revenue. This below-average margin results in a low score of 0/100, suggesting thin profitability after operating expenses. This is up from -70.7% the prior year.

Growth
59

Zai Lab Limited's revenue surged 15.3% year-over-year to $460.2M, reflecting rapid business expansion. This strong growth earns a score of 59/100.

Leverage
89

Zai Lab Limited carries a low D/E ratio of 0.64, meaning only $0.64 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 89/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
46

Zai Lab Limited's current ratio of 2.45 indicates adequate short-term liquidity, earning a score of 46/100. The company can meet its near-term obligations, though with limited headroom.

Cash Flow
0

While Zai Lab Limited generated -$150.8M in operating cash flow, capex of $8.1M consumed most of it, leaving -$158.9M in free cash flow. This results in a low score of 0/100, reflecting heavy capital investment rather than weak cash generation.

Returns
0

Zai Lab Limited generates a -24.5% ROE, indicating limited profit relative to shareholders' investment. This results in a returns score of 0/100. This is up from -30.6% the prior year.

Piotroski F-Score Weak
3/9

Zai Lab Limited passes 3 of 9 financial strength tests. 2 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), 1 of 2 efficiency signals pass.

Earnings Quality Low Quality
0.86x

For every $1 of reported earnings, Zai Lab Limited generates $0.86 in operating cash flow (-$150.8M OCF vs -$175.5M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Interest Coverage At Risk
-44.0x

Zai Lab Limited earns $-44.0 in operating income for every $1 of interest expense (-$229.4M vs $5.2M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$460.2M
YoY+15.3%
5Y CAGR+56.5%

Zai Lab Limited generated $460.2M in revenue in fiscal year 2025. This represents an increase of 15.3% from the prior year.

EBITDA
-$214.4M
YoY+20.7%

Zai Lab Limited's EBITDA was -$214.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 20.7% from the prior year.

Net Income
-$175.5M
YoY+31.7%

Zai Lab Limited reported -$175.5M in net income in fiscal year 2025. This represents an increase of 31.7% from the prior year.

EPS (Diluted)
$-0.16
YoY+38.5%

Zai Lab Limited earned $-0.16 per diluted share (EPS) in fiscal year 2025. This represents an increase of 38.5% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$158.9M
YoY+27.9%

Zai Lab Limited generated -$158.9M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 27.9% from the prior year.

Cash & Debt
$679.6M
YoY+51.1%
5Y CAGR+9.0%
10Y CAGR+48.4%

Zai Lab Limited held $679.6M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
1.11B
YoY+2.7%

Zai Lab Limited had 1.11B shares outstanding in fiscal year 2025. This represents an increase of 2.7% from the prior year.

Margins & Returns

Gross Margin
58.6%
YoY-4.5pp
5Y CAGR-7.2pp

Zai Lab Limited's gross margin was 58.6% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is down 4.5 percentage points from the prior year.

Operating Margin
-49.9%
YoY+20.8pp
5Y CAGR+566.6pp

Zai Lab Limited's operating margin was -49.9% in fiscal year 2025, reflecting core business profitability. This is up 20.8 percentage points from the prior year.

Net Margin
-38.1%
YoY+26.3pp
5Y CAGR+511.1pp

Zai Lab Limited's net profit margin was -38.1% in fiscal year 2025, showing the share of revenue converted to profit. This is up 26.3 percentage points from the prior year.

Return on Equity
-24.5%
YoY+6.0pp
5Y CAGR-1.5pp

Zai Lab Limited's ROE was -24.5% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 6.0 percentage points from the prior year.

Capital Allocation

R&D Spending
$220.9M
YoY-5.8%
5Y CAGR-0.2%
10Y CAGR+32.2%

Zai Lab Limited invested $220.9M in research and development in fiscal year 2025. This represents a decrease of 5.8% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$8.1M
YoY+43.2%
5Y CAGR-4.4%
10Y CAGR+27.1%

Zai Lab Limited invested $8.1M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 43.2% from the prior year.

ZLAB Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $127.6M+9.9% $116.1M+5.6% $110.0M+3.3% $106.5M-2.4% $109.1M+6.7% $102.3M+1.8% $100.5M+15.3% $87.1M
Cost of Revenue $62.3M+33.2% $46.8M+8.7% $43.0M+11.8% $38.5M-8.0% $41.8M+14.3% $36.6M+4.0% $35.1M+4.5% $33.6M
Gross Profit $65.3M-5.8% $69.3M+3.5% $67.0M-1.6% $68.0M+1.1% $67.3M+2.4% $65.7M+0.5% $65.4M+22.1% $53.5M
R&D Expenses $61.6M+28.6% $47.9M-5.3% $50.6M-16.7% $60.7M+16.2% $52.3M-20.8% $66.0M+7.1% $61.6M+12.8% $54.6M
SG&A Expenses $73.0M+4.2% $70.1M-1.3% $71.0M+12.0% $63.4M-23.2% $82.6M+22.9% $67.2M-15.7% $79.7M+15.2% $69.2M
Operating Income -$69.4M-42.2% -$48.8M+11.1% -$54.9M+2.5% -$56.3M+17.1% -$67.9M-0.1% -$67.9M+10.8% -$76.1M-8.2% -$70.3M
Interest Expense $1.4M-2.9% $1.4M+10.9% $1.3M+6.3% $1.2M+31.3% $904K+21.3% $745K+51.4% $492K+335.4% $113K
Income Tax -$2.9M $0 $0 $0 $0 $0 $0 $0
Net Income -$50.4M-40.2% -$36.0M+11.7% -$40.7M+15.9% -$48.4M+40.7% -$81.7M-96.0% -$41.7M+48.1% -$80.3M-50.1% -$53.5M
EPS (Diluted) N/A $-0.03+25.0% $-0.040.0% $-0.04 N/A $-0.04+50.0% $-0.08-60.0% $-0.05

ZLAB Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $1.2B+1.2% $1.2B-0.4% $1.2B-0.8% $1.2B-1.0% $1.2B+20.3% $985.3M-0.2% $987.4M-0.1% $988.4M
Current Assets $1.0B-1.3% $1.0B-0.1% $1.0B-0.7% $1.0B-0.8% $1.1B+22.1% $860.5M-1.1% $869.9M-2.1% $888.6M
Cash & Equivalents $679.6M-5.2% $717.2M-2.0% $732.2M-3.3% $757.3M+68.4% $449.7M-27.0% $616.1M-2.2% $630.0M-3.2% $650.8M
Inventory $74.7M+11.3% $67.1M+8.8% $61.7M+16.3% $53.1M+33.1% $39.9M+0.8% $39.5M-5.5% $41.8M+10.6% $37.9M
Accounts Receivable $106.1M+24.3% $85.4M-3.5% $88.5M+15.6% $76.6M-10.1% $85.2M+70.5% $50.0M-28.2% $69.6M+15.2% $60.4M
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $456.9M+14.5% $399.0M+7.2% $372.4M+2.7% $362.6M+5.1% $344.9M+8.6% $317.7M+12.2% $283.2M+25.2% $226.3M
Current Liabilities $416.2M+15.7% $359.8M+8.5% $331.5M+3.7% $319.8M+6.8% $299.4M+4.6% $286.3M+13.7% $251.7M+31.0% $192.1M
Long-Term Debt N/A N/A N/A N/A N/A N/A N/A N/A
Total Equity $715.5M-5.8% $759.9M-4.0% $791.7M-2.3% $810.8M-3.6% $840.9M+25.9% $667.7M-5.2% $704.2M-7.6% $762.2M
Retained Earnings -$2.6B-2.0% -$2.6B-1.4% -$2.5B-1.6% -$2.5B-2.0% -$2.5B-3.4% -$2.4B-1.8% -$2.3B-3.6% -$2.2B

ZLAB Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow -$26.0M+18.8% -$32.0M-3.3% -$31.0M+49.7% -$61.7M-10.6% -$55.8M-107.9% -$26.8M+36.4% -$42.2M+53.2% -$90.1M
Capital Expenditures $677K-77.5% $3.0M+4.2% $2.9M+88.1% $1.5M-41.0% $2.6M+93.7% $1.3M+81.1% $741K-23.9% $974K
Free Cash Flow -$26.7M+23.8% -$35.0M-3.4% -$33.9M+46.4% -$63.2M-8.3% -$58.4M-107.3% -$28.2M+34.4% -$42.9M+52.9% -$91.1M
Investing Cash Flow -$11.3M-179.0% -$4.0M-38.6% -$2.9M-100.9% $326.1M+193.8% -$347.8M-1063.6% -$29.9M-3432.5% -$846K-125.7% $3.3M
Financing Cash Flow -$430K-102.1% $20.8M+135.0% $8.8M-79.5% $43.1M-81.9% $237.8M+463.4% $42.2M+89.1% $22.3M-53.1% $47.5M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

ZLAB Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin 51.2%-8.5pp 59.7%-1.2pp 60.9%-3.0pp 63.9%+2.2pp 61.7%-2.5pp 64.2%-0.8pp 65.0%+3.6pp 61.4%
Operating Margin -54.4%-12.3pp -42.0%+7.9pp -49.9%+3.0pp -52.9%+9.4pp -62.3%+4.1pp -66.3%+9.3pp -75.7%+5.0pp -80.7%
Net Margin -39.5%-8.5pp -31.0%+6.0pp -37.0%+8.5pp -45.5%+29.4pp -74.9%-34.1pp -40.8%+39.1pp -79.9%-18.5pp -61.4%
Return on Equity -7.0%-2.3pp -4.7%+0.4pp -5.1%+0.8pp -6.0%+3.7pp -9.7%-3.5pp -6.2%+5.2pp -11.4%-4.4pp -7.0%
Return on Assets -4.3%-1.2pp -3.1%+0.4pp -3.5%+0.6pp -4.1%+2.8pp -6.9%-2.7pp -4.2%+3.9pp -8.1%-2.7pp -5.4%
Current Ratio 2.45-0.4 2.87-0.2 3.12-0.1 3.26-0.3 3.51+0.5 3.01-0.5 3.46-1.2 4.63
Debt-to-Equity 0.64+0.1 0.53+0.1 0.47+0.0 0.45+0.0 0.41-0.1 0.48+0.1 0.40+0.1 0.30
FCF Margin -20.9%+9.3pp -30.2%+0.6pp -30.8%+28.5pp -59.4%-5.9pp -53.5%-26.0pp -27.5%+15.2pp -42.7%+61.8pp -104.5%

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Frequently Asked Questions

Zai Lab Limited (ZLAB) reported $460.2M in total revenue for fiscal year 2025. This represents a 15.3% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Zai Lab Limited (ZLAB) revenue grew by 15.3% year-over-year, from $399.0M to $460.2M in fiscal year 2025.

No, Zai Lab Limited (ZLAB) reported a net income of -$175.5M in fiscal year 2025, with a net profit margin of -38.1%.

Zai Lab Limited (ZLAB) reported diluted earnings per share of $-0.16 for fiscal year 2025. This represents a 38.5% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Zai Lab Limited (ZLAB) had EBITDA of -$214.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Zai Lab Limited (ZLAB) had a gross margin of 58.6% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Zai Lab Limited (ZLAB) had an operating margin of -49.9% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Zai Lab Limited (ZLAB) had a net profit margin of -38.1% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Zai Lab Limited (ZLAB) has a return on equity of -24.5% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Zai Lab Limited (ZLAB) generated -$158.9M in free cash flow during fiscal year 2025. This represents a 27.9% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Zai Lab Limited (ZLAB) generated -$150.8M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Zai Lab Limited (ZLAB) had $1.2B in total assets as of fiscal year 2025, including both current and long-term assets.

Zai Lab Limited (ZLAB) invested $8.1M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Zai Lab Limited (ZLAB) invested $220.9M in research and development during fiscal year 2025.

Zai Lab Limited (ZLAB) had 1.11B shares outstanding as of fiscal year 2025.

Zai Lab Limited (ZLAB) had a current ratio of 2.45 as of fiscal year 2025, which is generally considered healthy.

Zai Lab Limited (ZLAB) had a debt-to-equity ratio of 0.64 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Zai Lab Limited (ZLAB) had a return on assets of -15.0% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Zai Lab Limited (ZLAB) had $679.6M in cash against an annual operating cash burn of $150.8M. This gives an estimated cash runway of approximately 54 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Zai Lab Limited (ZLAB) has a Piotroski F-Score of 3 out of 9, indicating weak financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Zai Lab Limited (ZLAB) has an earnings quality ratio of 0.86x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Zai Lab Limited (ZLAB) has an interest coverage ratio of -44.0x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Zai Lab Limited (ZLAB) scores 32 out of 100 on our Financial Profile, indicating weak overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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