Time-of-flight (TOF) mass spectrometry is an analytical instrument that identifies and measures molecules by turning them into charged particles, sending them down a flight path, and timing how long each particle takes to arrive — like timing runners to tell who's heavier or lighter. For investors, TOF instruments matter because they enable faster, more precise testing in drug development, diagnostics, quality control and materials research, which can drive product value, regulatory approval and recurring revenue streams.
vocus™ tof-mstechnical
vocus™ tof-ms is a type of scientific instrument that quickly identifies and measures tiny molecules in air or gas samples by separating them based on weight and detecting them in real time. For investors, it matters because sales and adoption of such instruments signal demand for environmental monitoring, industrial emissions control, and research services, and can create recurring revenue from consumables, service contracts, and data products—similar to how printers drive ink sales.
microwave-induced plasma (mip)-toftechnical
Microwave-induced plasma time-of-flight (MIP-TOF) is an analytical instrument that uses a microwave-generated plasma to turn a sample into charged particles, then measures how long those particles take to travel a set distance to identify and quantify the elements present. For investors, it matters because the technique delivers fast, sensitive, and low-preparation testing for trace metals and elements—critical for quality control, environmental monitoring, and materials development in industries like semiconductors and recycling.
focused ion beam (fib)-toftechnical
A focused ion beam (FIB)-TOF instrument combines a microscopic ion “scalpel” that slices or scans tiny areas with a detector that measures the speed of ejected particles to identify their chemical makeup. Think of it as cutting away and chemically fingerprinting successive thin layers of a material to build a detailed 3D map of composition and structure. For investors, FIB-TOF reveals defects, contamination, or material design problems that can affect product quality, manufacturing yield, regulatory risk and the pace of development.
scanning electron microscopestechnical
A scanning electron microscope is a laboratory instrument that scans a sample with a focused beam of electrons to produce very high-resolution images of surface shapes, tiny structures and material composition that ordinary microscopes cannot show. Investors care because these machines are essential in developing and quality-checking advanced products — from chips to batteries and medical devices — acting like an extremely powerful magnifying glass that helps reveal hidden defects or performance clues that can affect yields, costs and product timelines.
dart-tof-mstechnical
DART-TOF-MS is an analytical technique that quickly identifies and measures the chemicals in a sample by ionizing molecules in open air (DART) and then separating them by how fast they travel in a detector (TOF-MS). For investors, it matters because it speeds up drug discovery, quality control and contamination testing—like using a fast scanner at an airport to sort and flag suspect items—so companies can bring products to market faster and meet safety and regulatory standards.
gc-tof-mstechnical
GC-TOF-MS is a laboratory instrument that first separates complex mixtures into individual chemicals (like sorting letters by address) and then measures the weight of each component very quickly to identify what they are. Investors care because this testing method is used for product development, quality control and regulatory compliance; reliable, fast chemical analysis can reduce risk, speed time to market and affect costs and approval timelines.
metabolomicsmedical
Study of the small molecules and chemical patterns produced by cells, tissues or body fluids, often described as the body’s short-term chemical “fingerprint.” It matters to investors because these fingerprints can reveal how a drug or treatment is working, identify disease markers, guide patient selection, or shorten development time—similar to using a snapshot to judge whether a machine is running efficiently and needs adjustment.
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TOFWERK is a profitable innovator in compact, ultra-fast time-of-flight (TOF) mass spectrometry for real-time air and semiconductor cleanroom monitoring, food, flavors & fragrances markets, and FIB-TOF accessories for electron microscopes
The ultra-sensitive Vocus™ TOF-MS is customizable for real-time air and cleanroom monitoring applications
Microwave-induced plasma (MIP)-TOF systems with atto-to-femtogram detection limits for real-time quantification of trace elements and metals
Proprietary flow tube-based VUV CI sources for positive and negative trace organics, inorganics and PFAS contaminants
Focused Ion Beam (FIB)-TOF accessories for scanning electron microscopes
THUN, Switzerland--(BUSINESS WIRE)--
Bruker Corporation (Nasdaq: BRKR) today announced the acquisition of an additional 60% ownership stake in TOFWERK AG, a Switzerland-based innovator in ultra-fast time-of-flight (TOF) mass spectrometry technology for small molecule applied markets, consolidating Bruker’s ownership to 100%. The transaction adds ultra-fast TOF-MS technology for small-molecule markets, including atmospheric chemistry research, air quality monitoring, exposomics, foods, flavors & fragrances testing, and semiconductor cleanroom monitoring.
TOFWERK Headquarters in Thun, Switzerland
Founded in 2002 and headquartered in Thun, Switzerland, TOFWERK has built a strong reputation for small-footprint, ruggedized, high-speed, high-performance TOF mass spectrometers, including the development of high-efficiency, multi-reflector TOF technology. With >1,000 instruments worldwide, TOFWERK has grown profitably to 130 employees, with 2025 revenues of ~$40 million. TOFWERK will continue as a distinct brand within Bruker, preserving its Swiss engineering heritage, R&D excellence, OEM partnerships, and customer-centric culture.
“TOFWERK’s pioneering TOF technology and deep applications expertise perfectly complement our product offerings in small-molecule MS applied market segments and novel applications,” said Juergen Srega, Bruker CALID Group President.
“This is the natural next chapter for TOFWERK,” said Dr. Marc Gonin, co-founder of TOFWERK. “By joining Bruker, we gain the scale to amplify our impact in key markets of semiconductors and air quality monitoring, while we develop unique solutions like the novel DART-TOF-MS system for high-throughput, chromatography-free applications.”
Other products in the TOFWERK portfolio include the unique field-deployable MIP-TOF for trace element and metals analysis in air, customizable FIB-TOF OEM accessories for electron microscopy, an automated, high-throughput solution for aromatics in food or packaging, and the ecTOF™ system for EI and CI measurements in the same run for GC-TOF-MS metabolomics applications.
Financial terms of the transaction were not disclosed.
About Bruker Corporation – Leader of the Post-Genomic Era
Bruker is enabling scientists and engineers to make breakthrough post-genomic discoveries and develop new applications that improve the quality of human life. Bruker’s high performance scientific instruments and high value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity, and customer success in post-genomic life science molecular and cell biology research, in specialty diagnostics, in applied and biopharma applications, in microscopy and nanoanalysis, as well as in industrial and cleantech research, and next-gen semiconductor metrology in support of AI. Bruker offers differentiated, high-value life science and diagnostics systems and solutions in preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology, functional structural and condensate biology, as well as in clinical microbiology and molecular diagnostics. For more information, please visit www.bruker.com.
