Eton Pharmaceuticals Reports Fourth Quarter and Full Year 2025 Financial Results
Rhea-AI Summary
Eton Pharmaceuticals (NASDAQ: ETON) reported strong fourth quarter and full-year 2025 results with Q4 product sales of $21.3 million (up 83% year‑over‑year) and full‑year revenue of $80 million, more than double 2024. The company launched DESMODA, acquired U.S. rights to HEMANGEOL, and ended 2025 with $25.9 million cash. Management expects 2026 revenue to exceed $110 million with an Adjusted EBITDA margin above 30%.
Positive
- Product sales +83% year-over-year to $21.3M
- Full‑year revenue reached $80M, >2x 2024
- DESMODA FDA approval and commercial launch (Mar 9, 2026)
- Acquired U.S. rights to HEMANGEOL, accretive to 2026
- 2026 guidance: revenue >$110M with >30% Adjusted EBITDA
Negative
- Cash and cash equivalents of $25.9M at Dec 31, 2025
- General & Administrative expense rose to $8.9M from $6.7M
- R&D expense increased to $1.8M from $(0.9)M prior year
Key Figures
Market Reality Check
Peers on Argus
ETON is slightly up (0.53%) while momentum-screened peers like ESPR and CGC are also up modestly, but sector data flag this as stock-specific rather than a coordinated sector move.
Previous Earnings Reports
| Date | Event | Sentiment | Move | Catalyst |
|---|---|---|---|---|
| Nov 06 | Q3 2025 earnings | Positive | -11.7% | Reported 129% sales growth and positive EBITDA but shares fell post-release. |
| Aug 07 | Q2 2025 earnings | Positive | +12.3% | Strong Q2 growth and KHINDIVI launch drove a double-digit price gain. |
| May 13 | Q1 2025 earnings | Positive | +0.3% | Robust revenue growth and cash generation met with a modest positive move. |
| Mar 18 | Q4 2024 earnings | Positive | -4.0% | Record Q4 2024 revenue and milestones but shares traded lower afterward. |
| Nov 12 | Q3 2024 earnings | Positive | +15.6% | First positive GAAP net income from product sales drove a strong rally. |
Earnings releases have generally been positive fundamentally, but market reactions have been mixed, with 3 aligned and 2 divergent moves in recent comparable events.
Over the last five earnings cycles, ETON has reported rapid product sales growth and recurring positive non-GAAP profitability metrics. Prior quarters highlighted accelerating revenue, expanding product portfolio, and advancing NDAs, yet price reactions ranged from double-digit gains to notable selloffs. Against that backdrop, this Q4/FY 2025 report continues the pattern of strong growth and profitability, while guidance for 2026 revenue and margins extends the narrative of scaling the rare-disease franchise.
Historical Comparison
Across 5 prior earnings releases, ETON’s average move was about 2.5%. Today’s 0.53% pre-call gain sits well within the typical range for this catalyst.
Earnings updates over 2024–2025 show progression from initial profitability milestones to sustained revenue growth and expanding rare-disease portfolio, with this Q4/FY 2025 report adding higher sales, EBITDA, and forward guidance.
Market Pulse Summary
This announcement highlights substantial growth, with Q4 2025 product sales of $21.3 million (83% year-over-year) and full-year revenue of $80 million. It also introduces 2026 guidance for revenue above $110 million and at least a 30% Adjusted EBITDA margin. Investors may track uptake of DESMODA and HEMANGEOL, progress on label expansions and clinical studies, and how operating expenses evolve relative to the company’s expanding rare-disease portfolio.
Key Terms
adjusted ebitda financial
orphan drug regulatory
bioequivalence study medical
positron emission tomography (pet) medical
orphan drug designation regulatory
nda regulatory
AI-generated analysis. Not financial advice.
- Q4 2025 product sales of
$21.3 million , representing83% growth over Q4 2024 - Q4 2025 basic GAAP EPS of
$0.06 , fully diluted GAAP EPS of$0.05 , basic non-GAAP EPS of$0.21 , fully diluted non-GAAP EPS of$0.19 , and Adjusted EBITDA of$6.2 million - Launched DESMODA™, the first and only FDA-approved desmopressin oral solution
- Licensed U.S. rights to Orphan Drug HEMANGEOL®; expected to be accretive to 2026 earnings
- Company expects full year 2026 revenue to exceed
$110 million with an Adjusted EBITDA margin of over30% - Management to hold conference call today at 4:30pm ET
DEER PARK, Ill., March 19, 2026 (GLOBE NEWSWIRE) -- Eton Pharmaceuticals, Inc (“Eton” or “the Company”) (Nasdaq: ETON), an innovative pharmaceutical company focused on developing and commercializing treatments for rare diseases, today reported financial results for the quarter ended December 31, 2025.
“It was another phenomenal quarter for Eton with meaningful contributions from key products across our portfolio including INCRELEX, ALKINDI SPRINKLE, KHINDIVI, and GALZIN. The strong fourth quarter helped us cap off a transformational 2025. During the year we launched three major products, INCRELEX, GALZIN, and KHINDIVI, and delivered
“The recent FDA approval of DESMODA and the acquisition of HEMANGEOL have further accelerated our 2026 growth trajectory. DESMODA’s approval was highly anticipated by the endocrinology community, and the product received a very strong reception in its first week of launch. Our commercial team is fired up and fully mobilized, executing on the launch plan. Our entire team is also hard at work on the integration of HEMANGEOL and eager for our scheduled May 1st relaunch. Both of these products will be key growth contributors in 2026 and beyond. In addition, this year is poised to be our most active year yet on the clinical front, with key studies initiating or already initiated for the INCRELEX label expansion, the KHINDIVI reformulation, ET-700, and AMGLIDIA.”
“We are poised for another year of record financial results in 2026. For the full year, we expect to see revenue exceed
Fourth Quarter and Recent Business Highlights
Commercial launch of DESMODA. Eton launched DESMODA on March 9th, leveraging its existing team of pediatric endocrinology rare disease specialists. The product has received a strong reception from the patient and healthcare professional community, and numerous patients have already started on treatment. DESMODA is expected to significantly contribute to the Company’s long-term growth, with potential peak sales of
Acquired U.S. rights to Orphan Drug HEMANGEOL. The acquisition establishes a third call point for Eton’s sales team, pediatric dermatology. Eton anticipates integrating the product into its rare disease commercial infrastructure and extending its best-in-class Eton Cares patient support program to all HEMANGEOL patients, which includes the
Advancement of INCRELEX label harmonization study. In December, the company held a Type C meeting with the FDA to discuss the clinical pathway required to expand the U.S. FDA definition of Severe Primary IGF-1 Deficiency (SPIGFD) to match the broader E.U. definition. The Company believes the meeting was positive, and as a result, Eton submitted the proposed final study protocol to the FDA in February. The Company expects FDA feedback on the protocol by the end of March. If cleared, Eton would proceed with study initiation, with the goal of dosing the first patient in the third quarter of 2026.
Continued strong GALZIN growth, now exceeding 300 active patients. GALZIN growth continued to trend ahead of forecast in the fourth quarter of 2025 and so far in the first quarter of 2026. The Company’s targeted investment in rare disease specialists and education has increased awareness, access, and adoption and, earlier this month, the Company eclipsed 300 active patients on therapy. Eton continues to see a large growth opportunity to expand the treated population through conversion of patients currently taking over-the-counter products that are not FDA approved for Wilson disease.
Planned ET-700 pilot study. ET-700, the Company’s extended-release formulation of zinc acetate, will be tested in a proof-of-concept positron emission tomography (PET) study that is expected to initiate in April. The study will compare ET-700 to GALZIN and a placebo. If successful, the study would support the initiation of a dose ranging and pivotal study in early 2027.
Initiation of bioequivalence study to support KHINDIVI label expansion. The Company has initiated the bioequivalence study required to support submission of Eton’s revised KHINDIVI formulation designed to expand the product’s approved indication beyond its current restriction of children ages five and older. The study has been initiated, with the first patient dosed last week. The Company expects to receive preliminary top-line results late in the second quarter and receive the final study report needed for submission of the supplement in the third quarter of 2026. The Company anticipates a 10-month review for the submission, leading to a potential mid-2027 approval.
2026 Financial Guidance
The Company expects 2026 revenues to exceed
Fourth Quarter Financial Results
Net Revenue: Net revenues for the fourth quarter of 2025 were
Gross Profit: Gross profit for the fourth quarter of 2025 was
Adjusted gross profit, which adjusts for the impact of acquired inventory step-up adjustments and intangible amortization, was
Research and Development (R&D) Expenses: R&D expenses for the fourth quarter of 2025 were
General and Administrative (G&A) Expenses: G&A expenses for the fourth quarter of 2025 were
Adjusted G&A expense, which removes share-based compensation, transaction-related costs, and other one-time expenses, was
The fourth quarter of 2025 included
Adjusted Earnings Before Interest, Taxes, Depreciation and Amortization (Adjusted EBITDA): Adjusted EBITDA for the fourth quarter of 2025 was
Net Income/Loss: Net income for the fourth quarter of 2025 was
On a non-GAAP basis, the Company reported net income of
For a reconciliation of GAAP net loss to Earnings Before Interest, Taxes, Depreciation and Amortization EBITDA (“EBITDA”), Adjusted EBITDA and Adjusted Non-GAAP basic and fully diluted earnings per share to the most directly comparable GAAP financial measure, please see the tables below.
Cash Position: As of December 31, 2025, the Company had cash and cash equivalents of
Conference Call and Webcast Information
As previously announced, Eton Pharmaceuticals will host its fourth quarter 2025 conference call as follows:
| Date: | March 19, 2026 |
| Time: | 4:30 p.m. ET (3:30 p.m. CT) |
| Participant Webcast Link: | Click Here |
| Participant Call Link: | Click Here |
In addition to taking live questions from participants on the conference call, management will be answering emailed questions from investors. Investors can email questions to: investorrelations@etonpharma.com.
The live webcast can be accessed on the Investors section of Eton’s website at https://ir.etonpharma.com/. An archived webcast will be available on Eton’s website approximately two hours after the completion of the event and for 30 days thereafter.
* Conference call participants should register to obtain their dial-in and passcode details. Please be sure to register using a valid email address.
About Eton Pharmaceuticals
Eton is an innovative pharmaceutical company focused on developing and commercializing treatments for rare diseases. The Company currently has ten commercial rare disease products: KHINDIVIM, INCRELEX®, ALKINDI SPRINKLE®, DESMODA™, GALZIN®, HEMANGEOL®, PKU GOLIKE®, Carglumic Acid, Betaine Anhydrous, and Nitisinone. The Company has four additional product candidates in late-stage development: Amglidia®, ET-700, ET-800 and ZENEO® hydrocortisone autoinjector. For more information, please visit our website at www.etonpharma.com.
Forward-Looking Statements
Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including statements associated with the expected ability of Eton to undertake certain activities and accomplish certain goals and objectives. These statements include but are not limited to statements regarding Eton’s business strategy, Eton’s plans to develop and commercialize its product candidates, the safety and efficacy of Eton’s product candidates, Eton’s plans and expected timing with respect to regulatory filings and approvals, and the size and growth potential of the markets for Eton’s product candidates. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as “believes,” “anticipates,” “plans,” “expects,” “intends,” “will,” “goal,” “potential” and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Eton’s current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation, risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. These and other risks concerning Eton’s development programs and financial position are described in additional detail in Eton’s filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Eton undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.
Non-GAAP Financial Measures
In addition to the Company’s results of operations determined in accordance with U.S. generally accepted accounting principles (GAAP), which are presented and discussed above, management also utilizes Adjusted EBITDA, an unaudited financial measure that is not calculated in accordance with GAAP, to evaluate the Company’s financial results and performance and to plan and forecast future periods. Adjusted EBITDA is considered a “non-GAAP” financial measure within the meaning of Regulation G promulgated by the SEC. Management believes that this non-GAAP financial measure reflects an additional way of viewing aspects of the Company’s operations that, when viewed with GAAP results, provides a more complete understanding of the Company’s results of operations and the factors and trends affecting its business. Management believes Adjusted EBITDA provides meaningful supplemental information regarding the Company’s performance because (i) it allows for greater transparency with respect to key metrics used by management in its financial and operational decision-making; (ii) it excludes the impact of non-cash or, when specified, non-recurring items that are not directly attributable to the Company’s core operating performance and that may obscure trends in the Company’s core operating performance; and (iii) it is used by institutional investors and the analyst community to help analyze the Company’s results. However, Adjusted EBITDA and any other non-GAAP financial measures should be considered as a supplement to, and not as a substitute for, or superior to, the corresponding measures calculated in accordance with GAAP. Further, non-GAAP financial measures used by the Company and the way they are calculated may differ from the non-GAAP financial measures or the calculations of the same non-GAAP financial measures used by other companies, including the Company’s competitors.
Adjusted EBITDA
The Company defines Adjusted EBITDA as net loss, excluding the effects of stock-based compensation and expenses, interest, taxes, depreciation, amortization, investment loss, net, and, if any and when specified, other non-recurring income or expense items. Management believes that the most directly comparable GAAP financial measure to Adjusted EBITDA is net loss. Adjusted EBITDA has limitations and should not be considered as an alternative to gross profit or net loss as a measure of operating performance or to net cash provided by (used in) operating, investing, or financing activities as a measure of ability to meet cash needs.
Investor Relations:
Lisa M. Wilson, In-Site Communications, Inc.
T: 212-452-2793
E: lwilson@insitecony.com
| Eton Pharmaceuticals, Inc. Statements of Operations (In thousands, except per share amounts) | ||||||||||||||||
| For the three months ended | For the years ended | |||||||||||||||
| December 31, | December 31, | December 31, | December 31, | |||||||||||||
| 2025 | 2024 | 2025 | 2024 | |||||||||||||
| Revenues: | (Unaudited) | (Audited) | ||||||||||||||
| Licensing revenue | $ | — | $ | — | $ | 3,286 | $ | 500 | ||||||||
| Product sales and royalties, net | 21,281 | 11,647 | 76,664 | 38,511 | ||||||||||||
| Total net revenues | 21,281 | 11,647 | 79,950 | 39,011 | ||||||||||||
| Cost of sales: | ||||||||||||||||
| Licensing revenue | — | — | 825 | 270 | ||||||||||||
| Product sales and royalties | 8,181 | 5,171 | 36,385 | 15,330 | ||||||||||||
| Total cost of sales | 8,181 | 5,171 | 37,210 | 15,600 | ||||||||||||
| Gross profit | 13,100 | 6,476 | 42,740 | 23,411 | ||||||||||||
| Operating expenses: | ||||||||||||||||
| Research and development(1) | 1,780 | (871 | ) | 7,765 | 3,255 | |||||||||||
| General and administrative | 8,856 | 6,718 | 35,819 | 22,753 | ||||||||||||
| Total operating expenses | 10,636 | 5,847 | 43,584 | 26,008 | ||||||||||||
| Income (loss) from operations | 2,464 | 629 | (844 | ) | (2,597 | ) | ||||||||||
| Other expense: | ||||||||||||||||
| Interest and other expense, net | (1,050 | ) | (1,140 | ) | (3,714 | ) | (1,211 | ) | ||||||||
| Income (loss) before income tax expense | 1,414 | (511 | ) | (4,558 | ) | (3,808 | ) | |||||||||
| Income tax (benefit) expense | (69 | ) | 87 | 43 | 15 | |||||||||||
| Net (loss) income | $ | 1,483 | $ | (598 | ) | $ | (4,601 | ) | $ | (3,823 | ) | |||||
| Net income (loss) per share, basic and diluted | $ | 0.06 | $ | (0.02 | ) | $ | (0.17 | ) | $ | (0.15 | ) | |||||
| Weighted average number of common shares outstanding, basic and diluted | 26,937 | 26,135 | 26,908 | 25,895 | ||||||||||||
| Net income (loss) per share, diluted | $ | 0.05 | $ | (0.02 | ) | $ | (0.17 | ) | $ | (0.15 | ) | |||||
| Weighted average number of common shares outstanding, diluted | 31,243 | 26,135 | 26,908 | 25,895 | ||||||||||||
(1) During the three months ended December 31, 2024, we received
| Eton Pharmaceuticals, Inc. Balance Sheets (In thousands, except share and per share amounts) | ||||||||
| (Audited) | ||||||||
| December 31, 2025 | December 31, 2024 | |||||||
| Assets | ||||||||
| Current assets: | ||||||||
| Cash and cash equivalents | $ | 25,942 | $ | 14,936 | ||||
| Accounts receivable, net | 11,757 | 5,361 | ||||||
| Inventories, net | 15,419 | 15,232 | ||||||
| Prepaid expenses and other current assets | 7,463 | 5,492 | ||||||
| Total current assets | 60,581 | 41,021 | ||||||
| Property and equipment, net | 326 | 34 | ||||||
| Intangible assets, net | 30,878 | 34,881 | ||||||
| Operating lease right-of-use assets, net | 310 | 175 | ||||||
| Other long-term assets, net | 19 | 12 | ||||||
| Total assets | $ | 92,114 | $ | 76,123 | ||||
| Liabilities and stockholders’equity | ||||||||
| Current liabilities: | ||||||||
| Accounts payable | $ | 10,976 | $ | 4,167 | ||||
| Short-term debt, net of discount | 8,789 | — | ||||||
| Accrued Medicaid rebates | 9,317 | 6,866 | ||||||
| Accrued liabilities | 9,408 | 8,914 | ||||||
| Total current liabilities | 38,490 | 19,947 | ||||||
| Long-term debt, net of discount and including accrued fees | 21,769 | 29,811 | ||||||
| Operating lease liabilities, net of current portion | 460 | 107 | ||||||
| Other long-term liabilities | 5,241 | 1,830 | ||||||
| Total liabilities | 65,960 | 51,695 | ||||||
| Commitments and contingencies | ||||||||
| Stockholders’equity | ||||||||
| Common stock, | 27 | 27 | ||||||
| Additional paid-in capital | 138,621 | 132,294 | ||||||
| Accumulated deficit | (112,494 | ) | (107,893 | ) | ||||
| Total stockholders’equity | 26,154 | 24,428 | ||||||
| Total liabilities and stockholders’equity | $ | 92,114 | $ | 76,123 | ||||
| Eton Pharmaceuticals, Inc. Statements of Cash Flows (In thousands) (Audited) | ||||||||
| For the years ended | ||||||||
| December 31, 2025 | December 31, 2024 | |||||||
| Cash flows from (used in) operating activities | ||||||||
| Net loss | $ | (4,601 | ) | $ | (3,823 | ) | ||
| Adjustments to reconcile net loss to net cash from operating activities: | ||||||||
| Stock-based compensation | 5,512 | 3,165 | ||||||
| Depreciation and amortization | 4,044 | 1,146 | ||||||
| Inventory step-up | 5,094 | — | ||||||
| Excess and obsolete inventory reserve | 594 | 529 | ||||||
| Debt discount amortization | 696 | 1,109 | ||||||
| Non-cash lease expense | 44 | 70 | ||||||
| Changes in operating assets and liabilities, net of impact of business acquisition: | ||||||||
| Accounts receivable | (6,396 | ) | (3,118 | ) | ||||
| Inventories | (5,876 | ) | (1,839 | ) | ||||
| Prepaid expenses and other assets | (1,971 | ) | (3,349 | ) | ||||
| Accounts payable | 6,808 | 2,318 | ||||||
| Accrued Medicaid rebates | 2,451 | 3,239 | ||||||
| Accrued liabilities | 1,011 | 1,484 | ||||||
| Other non-current assets and liabilities | 3,114 | 38 | ||||||
| 10,524 | 969 | |||||||
| Cash flows from (used in) investing activities | ||||||||
| Purchases of property and equipment | (333 | ) | (26 | ) | ||||
| Acquisition of business | — | (30,000 | ) | |||||
| Purchase of product licensing rights | — | (9,988 | ) | |||||
| Net cash from (used in) investing activities | (333 | ) | (40,014 | ) | ||||
| Cash flows from (used in) financing activities | ||||||||
| Net proceeds from the issuance of long-term debt | — | 25,309 | ||||||
| Repayment of long-term debt | — | (1,155 | ) | |||||
| Common stock issued in private placement offering | — | 7,000 | ||||||
| Proceeds from stock option exercises | 598 | 1,191 | ||||||
| Employee stock purchase plan | 217 | 248 | ||||||
| Net cash from (used in) financing activities | 815 | 32,593 | ||||||
| Change in cash and cash equivalents | 11,006 | (6,452 | ) | |||||
| Cash and cash equivalents at beginning of period | 14,936 | 21,388 | ||||||
| Cash and cash equivalents at end of period | $ | 25,942 | $ | 14,936 | ||||
| Supplemental disclosures of cash flow information | ||||||||
| Cash paid for interest | $ | 3,325 | $ | 665 | ||||
| Cash paid for income taxes | $ | 118 | $ | 82 | ||||
| Eton Pharmaceuticals, Inc. Adjusted non-GAAP EBITDA Calculation and US GAAP to Non-GAAP Reconciliation (in thousands, except per share amounts) (Unaudited) | ||||||||||||||||
| For the three months ended | For the years ended | |||||||||||||||
| December 31, | December 31, | December 31, | December 31, | |||||||||||||
| 2025 | 2024 | 2025 | 2024 | |||||||||||||
| GAAP net income (loss) | $ | 1,483 | $ | (598 | ) | $ | (4,601 | ) | $ | (3,823 | ) | |||||
| Depreciation | 17 | 12 | 41 | 50 | ||||||||||||
| Intangible amortization expense | 1,000 | 343 | 4,003 | 1,096 | ||||||||||||
| Interest expense (including debt discount amortization and non-cash interest expenses) | 1,208 | 1,333 | 4,781 | 2,005 | ||||||||||||
| Income tax expense (benefit) | (69 | ) | 87 | 43 | 15 | |||||||||||
| EBITDA | $ | 3,639 | $ | 1,177 | $ | 4,267 | $ | (657 | ) | |||||||
| Other non-GAAP adjustments: | ||||||||||||||||
| Inventory step-up expense(1) | 1,421 | — | 5,094 | — | ||||||||||||
| Stock-based compensation(2) | 1,124 | 782 | 5,512 | 3,165 | ||||||||||||
| Severance expense(3) | — | — | 335 | — | ||||||||||||
| Acquisition/divestiture-related costs(4) | 7 | 140 | 581 | 415 | ||||||||||||
| Total of Other non-GAAP adjustments | 2,552 | 922 | 11,522 | 3,580 | ||||||||||||
| Adjusted EBITDA | $ | 6,191 | $ | 2,099 | $ | 15,789 | $ | 2,923 | ||||||||
| GAAP income (loss) before income tax | $ | 1,414 | $ | (511 | ) | $ | (4,558 | ) | $ | (3,808 | ) | |||||
| Non-GAAP adjustments: | ||||||||||||||||
| Depreciation(5) | 17 | 12 | 41 | 50 | ||||||||||||
| Intangible amortization expense(6) | 1,000 | 343 | 4,003 | 1,096 | ||||||||||||
| Inventory step-up expense(1) | 1,421 | - | 5,094 | - | ||||||||||||
| Share-based compensation(2) | 1,124 | 782 | 5,512 | 3,165 | ||||||||||||
| Severance expense(3) | — | — | 335 | — | ||||||||||||
| Acquisition/divestiture-related costs(4) | 7 | 140 | 581 | 415 | ||||||||||||
| Total pre-tax non-GAAP adjustments | 3,569 | 1,277 | 15,566 | 4,726 | ||||||||||||
| Income tax effect of pre-tax non-GAAP adjustments(7) | (372 | ) | 94 | 235 | 49 | |||||||||||
| Total non-GAAP adjustments | 3,941 | 1,183 | 15,331 | 4,677 | ||||||||||||
| Non-GAAP Net Income | $ | 5,355 | $ | 672 | $ | 10,773 | $ | 869 | ||||||||
| Weighted average number of common shares outstanding, basic | 26,937 | 26,135 | 26,908 | 25,895 | ||||||||||||
| Weighted average number of common shares outstanding, diluted | 31,243 | 29,320 | 31,046 | 27,458 | ||||||||||||
| GAAP income (loss) per share - Basic | $ | 0.06 | $ | (0.02 | ) | $ | (0.17 | ) | $ | (0.15 | ) | |||||
| Non-GAAP adjustments | 0.15 | 0.05 | 0.57 | 0.18 | ||||||||||||
| Non-GAAP earnings per share - Basic | $ | 0.21 | $ | 0.03 | $ | 0.40 | $ | 0.03 | ||||||||
| GAAP income (loss) per share - Basic | $ | 0.06 | $ | (0.02 | ) | $ | (0.17 | ) | $ | (0.15 | ) | |||||
| Non-GAAP adjustments | 0.13 | 0.04 | 0.49 | 0.17 | ||||||||||||
| Non-GAAP earnings per share - Diluted | $ | 0.19 | $ | 0.02 | $ | 0.32 | $ | 0.02 | ||||||||
| Eton Pharmaceuticals, Inc. Fourth Quarter 2025 GAAP to Non-GAAP Net Income (Loss) Reconciliation (in thousands) (Unaudited) | ||||||||||||||||||||||
| Fourth Quarter 2025 | GAAP | Depreciation and Intangible Amortization | Inventory Step-Up Expense | Stock Based Compensation | Severance Expense | Acquisition/ Divestiture Related Costs | Non-GAAP | |||||||||||||||
| Cost of sales | $ | 8,181 | (1,000 | ) | (1,421 | ) | - | - | - | $ | 5,760 | |||||||||||
| Research and development | 1,780 | - | - | (62 | ) | - | - | 1,718 | ||||||||||||||
| General and administrative | 8,856 | (17 | ) | - | (1,062 | ) | - | (7 | ) | 7,770 | ||||||||||||
| Interest and other expense, net | (1,050 | ) | - | - | - | - | - | (1,050 | ) | |||||||||||||
| Fourth Quarter 2024 | ||||||||||||||||||||||
| Cost of sales | $ | 5,171 | (343 | ) | - | - | - | - | $ | 4,828 | ||||||||||||
| Research and development | (871 | ) | - | - | (31 | ) | - | - | (902 | ) | ||||||||||||
| General and administrative | 6,718 | (12 | ) | - | (751 | ) | - | (140 | ) | 5,815 | ||||||||||||
| Interest and other expense, net | (1,140 | ) | - | - | - | - | - | (1,140 | ) | |||||||||||||
| Eton Pharmaceuticals, Inc. Full Year 2025 GAAP to Non-GAAP Net Income (Loss) Reconciliation (in thousands) (Unaudited) | |||||||||||||||||||||||
| Year Ended December 31, 2025 | |||||||||||||||||||||||
| Cost of sales | $ | 37,210 | (4,003 | ) | (5,094 | ) | - | - | - | $ | 28,113 | ||||||||||||
| Research and development | 7,765 | - | - | (182 | ) | - | - | 7,583 | |||||||||||||||
| General and administrative | 35,819 | (41 | ) | - | (5,330 | ) | (335 | ) | (581 | ) | 29,532 | ||||||||||||
| Interest and other expense, net | (3,714 | ) | - | - | - | - | - | (3,714 | ) | ||||||||||||||
| Year Ended December 31, 2024 | |||||||||||||||||||||||
| Cost of sales | $ | 15,600 | (1,096 | ) | - | - | - | - | $ | 14,504 | |||||||||||||
| Research and development | 3,255 | - | - | (276 | ) | - | - | 2,979 | |||||||||||||||
| General and administrative | 22,753 | (50 | ) | - | (2,889 | ) | - | (415 | ) | 19,399 | |||||||||||||
| Interest and other expense, net | (1,211 | ) | - | - | - | - | - | (1,211 | ) | ||||||||||||||
FAQ
What were ETON (NASDAQ: ETON) product sales in Q4 2025?
What earnings and Adjusted EBITDA did ETON report for Q4 2025?
How significant is the DESMODA launch for ETON after FDA approval?
What did ETON announce about acquiring HEMANGEOL U.S. rights and timing?
What guidance did ETON give for full‑year 2026 revenue and margins?
