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Harrow Reaffirms 2025 Full-Year Revenue Guidance of $270–$280 Million, Marking Another Year of Strong Growth

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Harrow (Nasdaq: HROW) reaffirmed full-year 2025 revenue guidance of $270–$280 million and announced operational expansions: doubling the VEVYE sales force by Memorial Day 2026, doubling the surgical sales force for TRIESENCE, and expanding IHEEZO into office-based procedures (estimated >2.5 million annual use cases).

The company is on track to file NDAs for MELT-300 and MELT-210 in H1 2027, launched the OneHarrow branding initiative, promoted Patrick W. Sullivan to Chief Commercial Officer, and ImprimisRx settled California regulatory matters with a ~$157,000 fine and exited California effective Feb 1, 2026.

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Positive

  • Reaffirmed 2025 revenue guidance of $270–$280 million
  • Plan to double VEVYE covered US territories from ~50 to 100 by Memorial Day 2026
  • MELT-300 NDA on track for submission in first half of 2027

Negative

  • ImprimisRx agreed to an administrative fine of approximately $157,000
  • ImprimisRx voluntarily exited the California market effective Feb 1, 2026

News Market Reaction – HROW

+9.67% 2.3x vol
10 alerts
+9.67% Session close to close
+9.6% Peak in 25 hr 53 min
$1.74B Market Cap
2.3x Rel. Volume

In the Feb 2 session, HROW gained 9.67%, reflecting a notable positive market reaction. Argus tracked a peak move of +9.6% during that session. Our momentum scanner triggered 10 alerts that day, indicating notable trading interest and price volatility. Trading volume was elevated at 2.3x the daily average, suggesting notable buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

The stock moved +9.7% in the session following this news. A strong positive reaction aligns with Har...
Analysis

The stock moved +9.7% in the session following this news. A strong positive reaction aligns with Harrow’s reaffirmed $270–$280 million 2025 revenue guidance and visible commercial expansion across VEVYE, IHEEZO, and TRIESENCE. Historical data show mostly modest moves around news, with occasional pullbacks on positive updates, so a large gain would stand out. Investors may watch execution on sales-force doubling, MELT-300 NDA timelines into H1 2027, and any impact from ImprimisRx’s California exit when assessing durability of such a move.

Key Figures

2025 revenue guidance: $270–$280 million Branded revenue goal: $230 million Office procedures market: 2.5 million +5 more
8 metrics
2025 revenue guidance $270–$280 million Reaffirmed full-year 2025 revenue guidance range
Branded revenue goal $230 million Target branded revenue in a single calendar quarter for PSUs
Office procedures market 2.5 million Estimated annual office-based ophthalmic procedures addressable for IHEEZO
Administrative fine $157,000 Approximate fine paid to California Board of Pharmacy in settlement
Adverse event rate 2 per 1,000,000 Approximate ADEs per 1,000,000 products dispensed by ImprimisRx
States served 49 states ImprimisRx markets served after voluntary exit from California
Covered VEVYE territories 50 to 100 Planned doubling of covered US territories by Memorial Day
MELT-300 NDA timing H1 2027 Company expectation to submit NDA for MELT-300

Historical Context

5 past events · Latest: Nov 24 (Neutral)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Nov 24 Investor conferences Neutral +0.2% Management scheduled fireside chats at two December 2025 investor conferences.
Nov 18 Acquisition closing Positive -1.4% Closed Melt Pharmaceuticals deal, adding MELT-210/300/400 pipeline assets.
Nov 10 Earnings report Positive +0.6% Reported strong Q3 2025 revenue growth and positive adjusted EBITDA.
Oct 27 Earnings notice Neutral -0.7% Announced timing and webcast details for upcoming Q3 2025 results.
Oct 06 Leadership changes Positive -7.2% ImprimisRx appointed new CEO and Head of Quality with strong track records.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news often produced modest price moves, though some positive strategic updates (acquisition, leadership changes) coincided with short-term pullbacks.

Recent Company History

Over the last few months, Harrow reported strong Q3 2025 financials, with revenue growth and profitability, announced and then closed the Melt Pharmaceuticals acquisition, and highlighted its participation in investor conferences. ImprimisRx leadership changes and governance filings also featured in recent disclosures. Price reactions were generally small, but the stock dropped notably on ImprimisRx leadership news. Today’s reaffirmed 2025 revenue guidance and commercial expansion updates continue the theme of growth execution and integration of the Melt pipeline.

Key Terms

new drug application, nda, pharmacokinetic, pk, +4 more
8 terms
new drug application regulatory
"toward filing a new drug application for MELT-300 and MELT-210."
A new drug application is a formal request submitted to government regulators seeking approval to market a new medicine. It is like a detailed proposal that shows the drug has been tested for safety and effectiveness. For investors, receiving approval signals that the drug may soon become available for sale, potentially leading to revenue growth and impacting the company's value.
nda regulatory
"All ancillary studies required to support a New Drug Application (NDA) submission"
An NDA, or nondisclosure agreement, is a legal contract that keeps certain information private between parties. It’s like a promise not to share sensitive details, helping protect business ideas, strategies, or data from being leaked or used without permission. For investors, NDAs help ensure that confidential information remains secure, enabling trust and open communication during business discussions.
pharmacokinetic medical
"including one non-clinical animal study and three pharmacokinetic (PK) studies"
Pharmacokinetic describes how a drug moves through and leaves the body — how it is absorbed, spread to tissues, broken down and excreted — like tracking a package from pickup to delivery and disposal. For investors, these properties determine effective dose, safety risks, how often a medicine must be taken, and how reliably it works, which in turn influence clinical trial success, regulatory approval chances, production complexity and a drug’s commercial value.
pk medical
"including one non-clinical animal study and three pharmacokinetic (PK) studies"
Pharmacokinetics (PK) describes how a drug moves through the body—how quickly it is absorbed, how it spreads to tissues, how the body breaks it down, and how it is eliminated. For investors, PK data help predict whether a medicine can reach effective levels without causing harm, how often it must be dosed, and whether drug interactions or patient differences could affect commercial success; think of it as the drug’s travel and timing profile inside the body.
adverse event medical
"maintains an extraordinary adverse event (ADE) record of approximately two ADEs"
An adverse event is any unwanted or harmful medical occurrence experienced by a person during a clinical trial or after using a product, whether or not it is caused by the treatment. Investors watch these reports because they can signal safety problems that delay approvals, trigger additional testing, reduce sales, or harm a company’s reputation — similar to how a series of car breakdowns can cut value and future sales for an automaker.
intravitreal medical
"including non-retina intravitreal and subconjunctival injections, YAG/laser"
An intravitreal treatment is one given by injecting medicine directly into the gel-like center of the eye, delivering drugs straight to the site of retinal disease rather than through pills or eye drops. Investors care because this delivery method affects development costs, regulatory review, clinical risk, manufacturing and distribution complexity, and reimbursement — all factors that influence a therapy’s commercial potential.
subconjunctival medical
"including non-retina intravitreal and subconjunctival injections, YAG/laser"
Subconjunctival describes something located just beneath the conjunctiva, the thin clear membrane that covers the white of the eye and the inner eyelid. For investors, it most often matters as a route for delivering drugs or injections directly to the eye — like slipping medicine under a protective film — which can increase local effect and reduce systemic exposure but also carries specific safety, dosing and regulatory considerations that affect clinical results and approval pathways.
vitrectomy medical
"from visualization during vitrectomy to treating inflammation related to"
Vitrectomy is a surgical procedure that removes the eye’s clear, gel-like substance (the vitreous) to treat problems such as bleeding, retinal tears, or detached tissue. Think of it like removing and replacing a cloudy windowpane or the fluid inside a camera to restore a clear picture. Investors care because the procedure drives demand for surgical instruments, implants, drugs and hospital services and its prevalence, cost and reimbursement shape revenue and regulatory risk for medical device and healthcare companies.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Doubling of VEVYE® Sales Force is On Track, Expansion of IHEEZO® Commercial Footprint to 
the Office-Based Setting Underway, and Doubling TRIESENCE® Commercial Footprint
in the Surgical-Based Setting is Proceeding

OneHarrow Initiative is Launched to Unify Branding under Harrow

Patrick W. Sullivan Promoted to Serve as Harrow’s Chief Commercial Officer

MELT-300 and MELT-210 Programs on Track for New Drug Application Filings

Harrow’s ImprimisRx Settles Pending Regulatory Matters with the California Board of Pharmacy

NASHVILLE, Tenn., Feb. 02, 2026 (GLOBE NEWSWIRE) -- Harrow (Nasdaq: HROW), a leading provider of ophthalmic disease management solutions in North America, today reaffirmed its full-year 2025 revenue guidance of between $270-280 million, and highlighted continued execution across its commercial and development programs. The Company announced it is on track to double the VEVYE sales force by Memorial Day, expand IHEEZO in the office-based setting, and double its surgical-based sales force supporting TRIESENCE, while making progress toward filing a new drug application for MELT-300 and MELT-210. Harrow’s ImprimisRx division reached a settlement for all pending matters with regulatory authorities in California.

Mark L. Baum, Chief Executive Officer of Harrow, stated, “Our team delivered another year of strong growth in 2025, supported by positive demand trends across our key revenue-driving products, as well as meaningful progress with other parts of our portfolio, all of which we look forward to discussing further in early March when we release our full year 2025 financial results. As we begin what we believe will be another record-setting year of growth, after many years operating under two separate commercial organizations (ImprimisRx and Harrow), the OneHarrow initiative will provide greater focus, tighter alignment, and a unified effort, driving disciplined and coordinated execution across a single organization. In addition, we have initiated hiring to double the sales force supporting VEVYE and the surgical sales force supporting TRIESENCE, both driven by growing momentum and customer interest in these cornerstone products in our portfolio. We are also excited to expand IHEEZO’s focus to a targeted, separately reimbursed office-based procedures market, which we estimate exceeds 2.5i million procedures annually. This expansion of IHEEZO establishes it as a foundational tool to improve everyday ophthalmic care and vastly increases the addressable market our team is covering.”

Baum added, “I also want to congratulate Pat Sullivan on his promotion to Chief Commercial Officer. Over the past 5 months, he has stepped in and has improved the structure and focus of our commercial organization, while maintaining a strong commitment to our principles of access and affordability, and Harrow’s core spirit of entrepreneurship, creativity, and outside-the-box thinking. I especially appreciate that Pat enthusiastically agreed to his new equity incentives as performance stock units that vest upon achieving our company-wide revenue goal of $230 million in branded revenue in a calendar quarter. In this regard, he is 100% aligned with what we are working toward and committed to delivering for our stockholders.”

VEVYE Sales Force Expansion

Driven by recent coverage wins with the largest pharmacy benefit manager of commercial lives in the US, which took effect on January 1, 2026, along with expected stabilization of net pricing, and additional new coverage opportunities, Harrow has begun recruiting efforts to double the number of covered US territories from approximately 50 to 100 by Memorial Day. This investment in labor is expected to fuel continued market-share expansion for VEVYE in 2026 and beyond.

IHEEZO Commercial Expansion

At the recent Hawaiian Eye & Retina Meeting, Harrow began expanding its IHEEZO commercial focus beyond retina practices to the office-based setting, by targeting, more broadly, the growing market for office-based ophthalmic procedures. Harrow estimates this to exceed 2.5 million annual use cases. The Company expects this initiative to accelerate demand for IHEEZO and drive new adoption across anesthesia-dependent, reimbursed procedures, including non-retina intravitreal and subconjunctival injections, YAG/laser and glaucoma laser procedures, foreign body removals, and selected ocular surface and eyelid procedures.

TRIESENCE Sales Force Expansion

In the coming months, Harrow intends to double the size of its surgical sales force supporting TRIESENCE. This investment is based on consistently positive clinical feedback from surgeons and improving demand metrics, including a sustained increase in interest in adopting and reordering TRIESENCE as a preferred injectable anti-inflammatory for various on-label use cases in the office and surgical suite, from visualization during vitrectomy to treating inflammation related to surgical interventions.

OneHarrow Initiative

Harrow has launched OneHarrow, a company-wide commitment to operate under a single brand, with a shared mission to expand patient access, improve affordability, and deliver better clinical outcomes with Harrow’s comprehensive portfolio of disease management solutions. As part of OneHarrow, all Harrow products, including its compounded formulations, will be marketed and sold through under the Harrow brand by a unified organization that is more aligned, more efficient, and better positioned to serve providers and patients.

Patrick W. Sullivan is Promoted to Serve as Chief Commercial Officer

Harrow is pleased to announce the promotion of Patrick W. Sullivan to serve as its Chief Commercial Officer. As part of Mr. Sullivan’s charge, he will continue his work to strengthen Harrow’s commercial foundation and focus our team on the achievement our 2027 financial goal as the Company continues to evolve into a national position as a broad-based provider of ophthalmic disease management solutions. Mr. Sullivan joined Harrow as its Head of Commercial in August 2025, bringing over 25 years of commercial leadership experience. Before joining the Company, Mr. Sullivan was Vice President of Marketing, Neurology Portfolio at Corium Therapeutics, where he led U.S. commercialization and launches in ADHD and dementia. Previously, he served as Global Commercial Head and Executive Director at AstraZeneca, directing the launch of Evrenzo® (roxadustat), a first-in-class anemia therapy. Earlier in his career, he held leadership roles at Shire, Adolor, Novartis, and Bayer. Mr. Sullivan holds a B.S. in Business Administration from Widener University.

MELT-300 Update

Following the close of Harrow’s acquisition of Melt Pharmaceuticals, Harrow has completed the operational integration of Melt’s programs into its organization. All ancillary studies required to support a New Drug Application (NDA) submission for MELT-300, including one non-clinical animal study and three pharmacokinetic (PK) studies, have now been initiated. Harrow remains on track to submit the NDA for MELT-300 in the first half of 2027.

ImprimisRx Settles Pending Regulatory Matters and Voluntarily Exits California

After serving California eyecare professionals and their patients for more than a decade, ImprimisRx entered into a settlement with the California Board of Pharmacy, agreed to an administrative fine of approximately $157,000, and voluntarily exited the California market effective February 1, 2026. While ImprimisRx maintains an extraordinary adverse event (ADE) record of approximately two ADEs for every 1,000,000 products dispensed, due to California’s increasingly unpredictable, costly, and punitive regulatory environment, and the associated state-specific compliance and professional services costs regularly incurred with lawyers, lobbyists, and consultants, ImprimisRx has determined that continued service to the state is no longer feasible or sustainable. ImprimisRx will now focus on optimizing its compounding operations and serving patients and providers in the 49 other states in which it is licensed. The decision to exit California is not financially material to Harrow, and the Company remains committed to working closely with eyecare professionals and patients to ensure continuity of care.

Harrow will continue to serve the California market with its portfolio of branded products.

About Harrow

Harrow, Inc. (Nasdaq: HROW) is a leading provider of ophthalmic disease management solutions in North America, offering a comprehensive portfolio of products that address conditions affecting both the front and back of the eye, such as dry eye disease, wet (or neovascular) age-related macular degeneration, cataracts, refractive errors, glaucoma and a range of other ocular surface conditions and retina diseases. Harrow was founded with a commitment to deliver safe, effective, accessible, and affordable medications that enhance patient compliance and improve clinical outcomes. For more information about Harrow, please visit harrow.com and connect with us on LinkedIn.

Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this release that are not historical facts may be considered “forward-looking statements.” This press release may include preliminary or unaudited financial results and estimates, which are subject to completion of customary year-end closing procedures and audit review; actual results may differ, potentially materially, from these preliminary results and estimates.   Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties, which may cause results to differ materially and adversely from the statements contained herein. Some of the potential risks and uncertainties that could cause actual results to differ from those predicted include, among others, risks related to: liquidity or results of operations; our ability to successfully implement our business plan, develop and commercialize our products, product candidates and proprietary formulations in a timely manner or at all, identify and acquire additional products, manage our pharmacy operations, service our debt, obtain financing necessary to operate our business, recruit and retain qualified personnel, manage any growth we may experience and successfully realize the benefits of our previous acquisitions and any other acquisitions and collaborative arrangements we may pursue; competition from pharmaceutical companies, outsourcing facilities and pharmacies; general economic and business conditions, including inflation and supply chain challenges; regulatory and legal risks, including litigation matters, and other uncertainties related to our pharmacy operations and the pharmacy and pharmaceutical business in general; physician interest in and market acceptance of our current and any future formulations and compounding pharmacies generally. These and additional risks and uncertainties are more fully described in Harrow’s filings with the Securities and Exchange Commission (SEC), including its Annual Report on Form 10-K for the year ended December 31, 2024, subsequent Quarterly Reports on Form 10-Q, and other filings with the SEC. Such documents may be read free of charge on the SEC’s website at sec.gov. Undue reliance should not be placed on forward-looking statements, which speak only as of the date they are made. Except as required by law, Harrow undertakes no obligation to update any forward-looking statements to reflect new information, events, or circumstances after the date they are made, or to reflect the occurrence of unanticipated events.

Contacts:
Mike Biega
Vice President of Investor Relations and Communications
mbiega@harrowinc.com
617-913-8890

i CMS Medicare Physician & Other Practitioners (CY2023)


FAQ

What does Harrow (HROW) reaffirm about its 2025 revenue guidance?

Harrow reaffirmed full-year 2025 revenue guidance of $270–$280 million. According to the company, this reflects continued demand for key products and underpins planned commercial investments in 2026.

When will Harrow double the VEVYE sales force and what does that mean for HROW?

Harrow plans to double VEVYE-covered US territories to ~100 by Memorial Day 2026. According to the company, this hiring is driven by recent coverage wins and aims to expand market share and stabilise net pricing.

What is the timeline for MELT-300 and MELT-210 NDA filings for HROW?

Harrow expects to submit the MELT-300 NDA in the first half of 2027. According to the company, required ancillary nonclinical and PK studies have been initiated to support the filing.

Why did Harrow’s ImprimisRx exit California and what was the cost impact for HROW?

ImprimisRx voluntarily exited California effective Feb 1, 2026 after settling regulatory matters with a ~$157,000 fine. According to the company, the exit is not financially material to Harrow and improves regulatory predictability.

What is OneHarrow and how could it affect Harrow’s commercial strategy (HROW)?

OneHarrow unifies branding and commercial operations under a single Harrow organization. According to the company, the initiative aims to improve alignment, efficiency, and coordinated go-to-market execution across its portfolio.