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Century Therapeutics Announces Two Upcoming Presentations at the EULAR 2025 Congress

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Century Therapeutics (NASDAQ: IPSC) announced two upcoming presentations at the EULAR 2025 Congress in Barcelona, Spain, from June 11-14, 2025. The presentations will showcase data from the company's preclinical cell therapy pipeline and investigational programs for autoimmune diseases and cancer.

The first presentation will focus on CNTY-101, an iPSC-derived allogeneic CD19 targeting CAR-NK product, demonstrating its potential for B cell depletion in autoimmune diseases. The second presentation will highlight the generation of various iPSC-derived cell therapies, including CAR-NK, γδ CAR-T, and αβ CAR-T cells, for treating B cell-mediated autoimmune diseases. Both presentations are scheduled for June 12, 2025.

Century Therapeutics (NASDAQ: IPSC) ha annunciato due presentazioni in programma al Congresso EULAR 2025 che si terrà a Barcellona, Spagna, dall'11 al 14 giugno 2025. Le presentazioni mostreranno dati relativi alla pipeline preclinica di terapie cellulari dell'azienda e ai programmi di ricerca per malattie autoimmuni e cancro.

La prima presentazione si concentrerà su CNTY-101, un prodotto allogenico CAR-NK derivato da iPSC che mira al CD19, evidenziando il suo potenziale nella deplezione delle cellule B nelle malattie autoimmuni. La seconda presentazione metterà in luce la generazione di diverse terapie cellulari derivate da iPSC, inclusi CAR-NK, γδ CAR-T e αβ CAR-T, per il trattamento di malattie autoimmuni mediate da cellule B. Entrambe le presentazioni sono previste per il 12 giugno 2025.

Century Therapeutics (NASDAQ: IPSC) anunció dos presentaciones próximas en el Congreso EULAR 2025 que se celebrará en Barcelona, España, del 11 al 14 de junio de 2025. Las presentaciones mostrarán datos de la cartera preclínica de terapias celulares de la compañía y de sus programas de investigación para enfermedades autoinmunes y cáncer.

La primera presentación se centrará en CNTY-101, un producto CAR-NK alogénico derivado de iPSC que apunta a CD19, demostrando su potencial para la eliminación de células B en enfermedades autoinmunes. La segunda presentación destacará la generación de diversas terapias celulares derivadas de iPSC, incluyendo CAR-NK, γδ CAR-T y αβ CAR-T, para tratar enfermedades autoinmunes mediadas por células B. Ambas presentaciones están programadas para el 12 de junio de 2025.

Century Therapeutics (NASDAQ: IPSC)는 2025년 6월 11일부터 14일까지 스페인 바르셀로나에서 열리는 EULAR 2025 학회에서 두 건의 발표를 예정했다고 발표했습니다. 이번 발표에서는 회사의 전임상 세포 치료 파이프라인과 자가면역 질환 및 암에 대한 연구 프로그램 데이터를 선보일 예정입니다.

첫 번째 발표는 iPSC 유래 동종 CD19 표적 CAR-NK 제품인 CNTY-101에 초점을 맞추어 자가면역 질환에서 B 세포 제거 가능성을 보여줍니다. 두 번째 발표에서는 CAR-NK, γδ CAR-T, αβ CAR-T 세포 등 다양한 iPSC 유래 세포 치료제 생성에 대해 다루며, B 세포 매개 자가면역 질환 치료를 목표로 합니다. 두 발표 모두 2025년 6월 12일에 예정되어 있습니다.

Century Therapeutics (NASDAQ : IPSC) a annoncé deux présentations à venir lors du Congrès EULAR 2025 à Barcelone, en Espagne, du 11 au 14 juin 2025. Ces présentations mettront en avant des données issues de la pipeline préclinique de thérapies cellulaires de l'entreprise ainsi que de ses programmes d'investigation pour les maladies auto-immunes et le cancer.

La première présentation portera sur CNTY-101, un produit CAR-NK allogénique dérivé de cellules iPSC ciblant le CD19, démontrant son potentiel pour la déplétion des cellules B dans les maladies auto-immunes. La seconde présentera la génération de diverses thérapies cellulaires dérivées de iPSC, incluant CAR-NK, γδ CAR-T et αβ CAR-T, destinées au traitement des maladies auto-immunes à médiation par les cellules B. Les deux présentations sont prévues pour le 12 juin 2025.

Century Therapeutics (NASDAQ: IPSC) kündigte zwei bevorstehende Präsentationen auf dem EULAR 2025 Kongress in Barcelona, Spanien, vom 11. bis 14. Juni 2025 an. Die Präsentationen werden Daten aus der präklinischen Zelltherapie-Pipeline des Unternehmens sowie aus Forschungsprogrammen zu Autoimmunerkrankungen und Krebs vorstellen.

Die erste Präsentation konzentriert sich auf CNTY-101, ein iPSC-abgeleitetes allogenes CD19-gerichtetes CAR-NK-Produkt, das sein Potenzial zur B-Zell-Depletion bei Autoimmunerkrankungen demonstriert. Die zweite Präsentation hebt die Herstellung verschiedener iPSC-abgeleiteter Zelltherapien hervor, darunter CAR-NK, γδ CAR-T und αβ CAR-T-Zellen, zur Behandlung B-Zell-vermittelter Autoimmunerkrankungen. Beide Präsentationen sind für den 12. Juni 2025 geplant.

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PHILADELPHIA, May 28, 2025 (GLOBE NEWSWIRE) -- Century Therapeutics, Inc. (‘Century’, NASDAQ: IPSC), an innovative biotechnology company developing induced pluripotent stem cell (iPSC)-derived cell therapies in autoimmune disease and cancer, today announced two presentations at the upcoming European Alliance of Associations for Rheumatology (EULAR) 2025 Congress, which is being held from June 11-14, 2025, at Fira de Barcelona in Barcelona, Spain. The presentations will highlight data supporting the company’s emerging preclinical cell therapy pipeline and investigational programs for autoimmune diseases and cancer.

Details of the presentations are as follows:

Abstract Number: 1380
Title: CNTY-101, an iPSC-Derived Allogeneic CD19 Targeting CAR-NK Product, Exhibits Robust B Cell Depletion and Has Broad Potential for Development in B Cell-Driven Autoimmune Diseases
Presentation Type: Poster Tour
Session Date/Time: Thursday, June 12, 2025, 9:30 a.m. – 9:36 a.m. CEST
Presenter: Hongxia Zhang, Ph.D., Director of Translational Development at Century Therapeutics

Abstract Number: 2099
Title: Generation of iPSC-Derived CAR-NK, γδ CAR-T, and αβ CAR-T Cells with Potent Activity for Treatment of B cell-mediated Autoimmune Diseases
Presentation Type: Poster Tour
Session Date/Time: Thursday, June 12, 2025, 9:42 a.m. – 9:48 a.m. CEST
Presenter: Jonathan Kurtz, Ph.D., Director of Molecular Immunology at Century Therapeutics

Additional information, including the accepted abstracts, can be accessed on the EULAR 2025 Congress website. Presentation materials will be made available in the Science section under Scientific Resources of the company’s website following the event.

About Century Therapeutics
Century Therapeutics (NASDAQ: IPSC) is a clinical-stage biotechnology company leveraging its expertise in cellular reprogramming, genetic engineering, and manufacturing to develop cell therapies with the potential to provide meaningful advantages over existing cell therapies. Century’s genetically engineered, iPSC-derived cell therapy pipeline includes programs designed to address autoimmune diseases and cancers. Century believes its commitment to developing off-the-shelf cell therapies will expand patient access and provide an opportunity to advance the course of autoimmune disease and cancer care. For more information on Century Therapeutics, please visit www.centurytx.com and connect with us on LinkedIn.

Forward-Looking Statements
This press release contains forward-looking statements within the meaning of, and made pursuant to the safe harbor provisions of, The Private Securities Litigation Reform Act of 1995. All statements contained in this press release, other than statements of historical facts or statements that relate to present facts or current conditions, including but not limited to, statements regarding our clinical development plans and timelines are forward-looking statements. These statements involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance, or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. In some cases, you can identify forward-looking statements by terms such as “may,” “might,” “will,” “should,” “expect,” “plan,” “aim,” “seek,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “forecast,” “potential” or “continue” or the negative of these terms or other similar expressions. The forward-looking statements in this press release are only predictions. We have based these forward-looking statements largely on our current expectations and projections about future events and financial trends that we believe may affect our business, financial condition, and results of operations. These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties and assumptions, some of which cannot be predicted or quantified and some of which are beyond our control, including, among others: our ability to successfully advance our current and future product candidates through development activities, preclinical studies, and clinical trials; our dependence on the success of our lead product candidate, CNTY-101; our ability to progress CNTY-101 through clinical development; our ability to meet development milestones on anticipated timelines; uncertainties inherent in the results of preliminary data, pre-clinical studies and earlier-stage clinical trials, which may not be predictive of final results or the results of later-stage clinical trials; our ability to obtain clearance of our future IND or CTA submissions and commence and complete clinical trials on expected timelines, or at all; our reliance on the maintenance of certain key collaborative relationships for the manufacturing and development of our product candidates; the timing, scope and likelihood of regulatory filings and approvals, including final regulatory approval of our product candidates; the impact of geopolitical issues, trade disputes and tariffs, banking instability and inflation on our business and operations, supply chain and labor force; the performance of third parties in connection with the development of our product candidates, including third parties conducting our clinical trials as well as third-party suppliers and manufacturers; our ability to successfully commercialize our product candidates and develop sales and marketing capabilities, if our product candidates are approved; our ability to recruit and maintain key members of management and our ability to maintain and successfully enforce adequate intellectual property protection. These and other risks and uncertainties are described more fully in the “Risk Factors” section of our most recent filings with the Securities and Exchange Commission and available at www.sec.gov. You should not rely on these forward-looking statements as predictions of future events. The events and circumstances reflected in our forward-looking statements may not be achieved or occur, and actual results could differ materially from those projected in the forward-looking statements. Moreover, we operate in a dynamic industry and economy. New risk factors and uncertainties may emerge from time to time, and it is not possible for management to predict all risk factors and uncertainties that we may face. Except as required by applicable law, we do not plan to publicly update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.

For More Information:

Century Therapeutics
Morgan Conn, Ph.D.
Chief Financial Officer
investor.relations@centurytx.com

JPA Health
Sarah McCabe
smccabe@jpa.com


FAQ

What will Century Therapeutics (IPSC) present at EULAR 2025?

Century Therapeutics will present two studies: one on CNTY-101, their iPSC-derived CAR-NK product for B cell depletion, and another on the generation of various iPSC-derived cell therapies for B cell-mediated autoimmune diseases.

When and where is Century Therapeutics (IPSC) presenting at EULAR 2025?

The presentations will take place on Thursday, June 12, 2025, between 9:30-9:48 a.m. CEST at the Fira de Barcelona in Barcelona, Spain.

What is CNTY-101 and what is its potential application?

CNTY-101 is an iPSC-derived allogeneic CD19 targeting CAR-NK product that shows robust B cell depletion potential and could be developed for treating B cell-driven autoimmune diseases.

What types of cell therapies is Century Therapeutics (IPSC) developing?

Century Therapeutics is developing iPSC-derived cell therapies including CAR-NK, γδ CAR-T, and αβ CAR-T cells for treating autoimmune diseases and cancer.
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