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Karyopharm to Participate in Baird's Biotech Discovery Series

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Karyopharm (Nasdaq: KPTI) announced that its senior management team and Dr. Claire Harrison will participate in a virtual fireside chat as part of Baird's Biotech Discovery Series on Wednesday, December 10, 2025 at 12:00 p.m. ET.

Dr. Harrison is Professor of Myeloproliferative Neoplasms and Clinical Director at Guy's and St. Thomas' NHS Foundation Trust and is described as a leading international expert in myelofibrosis. A live webcast will be available under the company's Investor "Events & Presentations" page and will be posted for replay after the event.

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News Market Reaction – KPTI

+2.43% 2.1x vol
12 alerts
+2.43% Session close to close
+6.2% Peak in 4 hr 56 min
$111.09M Market Cap
2.1x Rel. Volume

In the Dec 8 session, KPTI gained 2.43%, reflecting a moderate positive market reaction. Argus tracked a peak move of +6.2% during that session. Our momentum scanner triggered 12 alerts that day, indicating notable trading interest and price volatility. Trading volume was elevated at 2.1x the daily average, suggesting notable buying interest.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement highlights Karyopharm’s participation in Baird’s Biotech Discovery Series, featuri...
Analysis

This announcement highlights Karyopharm’s participation in Baird’s Biotech Discovery Series, featuring a virtual fireside chat focused on myelofibrosis and related myeloproliferative neoplasms. It continues a pattern of conference visibility and investor communication rather than introducing new clinical or financial data. In light of prior disclosures around a $33.1M Q3 2025 net loss and going‑concern risks, investors may watch for how management frames trial progress, financing flexibility, and previously registered resales of up to 2,805,688 shares.

Key Figures

Event date: December 10, 2025 Event time: 12:00 p.m. ET
2 metrics
Event date December 10, 2025 Date of Baird Biotech Discovery Series virtual fireside chat
Event time 12:00 p.m. ET Scheduled start time for the virtual fireside chat

Historical Context

5 past events · Latest: Dec 01 (Neutral)
5 events
Date Event Sentiment 24h Move Catalyst
Dec 01 Inducement grants Neutral -6.8% Inducement stock options and RSUs granted to new hires under 2022 plan.
Dec 01 Conference participation Neutral +2.3% Management fireside chat at Piper Sandler healthcare conference with webcast replay.
Nov 03 Inducement RSU grant Neutral +4.7% Single-employee RSU inducement grant under Nasdaq Listing Rule 5635(c)(4).
Nov 03 Earnings and pipeline Neutral +4.7% Q3 2025 results and progress, including SENTRY Phase 3 myelofibrosis enrollment.
Oct 27 Earnings date notice Neutral +1.3% Announcement of Q3 2025 results date and related conference call details.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Recent Company History

Over the last few months, Karyopharm has reported Q3 2025 results with $44.0M revenue and highlighted completion of enrollment in the Phase 3 SENTRY myelofibrosis trial. The company also issued multiple inducement RSU and option grants and participated in investor conferences, with share-price reactions ranging from about -6.78% to +4.66%. Today’s Baird Biotech Discovery Series fireside chat fits into this pattern of ongoing investor-relations outreach rather than a discrete clinical or financial catalyst.

Key Terms

myeloproliferative neoplasms, myelofibrosis
2 terms
myeloproliferative neoplasms medical
"Dr. Harrison is Professor of Myeloproliferative Neoplasms, Clinical Director..."
Myeloproliferative neoplasms are a group of blood cancers caused by the bone marrow producing too many of one or more types of blood cells, which can crowd out normal cells and impair blood flow. Investors pay attention because these conditions create clear medical needs and predictable markets for diagnostics, therapies and follow-up care—similar to a failing factory that creates demand for repair services and replacement parts—affecting drug development, regulatory milestones and potential sales.
myelofibrosis medical
"...and a leading international expert in myelofibrosis."
A bone marrow disorder in which healthy, spongy marrow is gradually replaced by scar tissue, like a garden soil turned to concrete so seeds can’t grow. That replacement reduces production of red and white blood cells and platelets, causing anemia, fatigue, infections and an enlarged spleen. Investors care because the condition creates demand for therapies, clinical trials and regulatory decisions that can materially affect drug sales and company valuations.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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NEWTON, Mass., Dec. 8, 2025 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company's senior management team and Dr. Claire Harrison will participate in a virtual fireside chat as part of Baird's Biotech Discovery Series on Wednesday, December 10, 2025 at 12:00 p.m. ET. Dr. Harrison is Professor of Myeloproliferative Neoplasms, Clinical Director at Guy's and St. Thomas' NHS Foundation Trust and a leading international expert in myelofibrosis.

A live webcast of the event can be accessed under "Events & Presentations" in the Investor section of the Company's website, https://investors.karyopharm.com/events-presentations, and will be available for replay following the event.

About Karyopharm Therapeutics

Karyopharm Therapeutics Inc. (Nasdaq: KPTI) is a commercial-stage pharmaceutical company whose dedication to pioneering novel cancer therapies is fueled by a belief in the extraordinary strength and courage of patients with cancer. Since its founding, Karyopharm has been an industry leader in oral compounds that address nuclear export dysregulation, a fundamental mechanism of oncogenesis. Karyopharm's lead compound and first-in-class, oral exportin 1 (XPO1) inhibitor, XPOVIO® (selinexor), is approved in the U.S. and marketed by the Company in three oncology indications. It has also received regulatory approvals in various indications in 50 ex-U.S. territories and countries, including the European Union, the United Kingdom (as NEXPOVIO®) and China. Karyopharm has a focused pipeline targeting indications in multiple high unmet need cancers, including in multiple myeloma, endometrial cancer, myelofibrosis, and diffuse large B-cell lymphoma (DLBCL). For more information about our people, science and pipeline, please visit www.karyopharm.com, and follow us on LinkedIn and on X at @Karyopharm.

XPOVIO® and NEXPOVIO® are registered trademarks of Karyopharm Therapeutics Inc. Any other trademarks referred to in this release are the property of their respective owners.

(PRNewsfoto/Karyopharm Therapeutics Inc.)

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/karyopharm-to-participate-in-bairds-biotech-discovery-series-302634110.html

SOURCE Karyopharm Therapeutics Inc.

FAQ

When will Karyopharm (KPTI) present at Baird's Biotech Discovery Series?

Karyopharm will present on Wednesday, December 10, 2025 at 12:00 p.m. ET.

Who from Karyopharm will participate in the December 10, 2025 fireside chat (KPTI)?

The company's senior management team and Dr. Claire Harrison will participate in the virtual fireside chat.

How can investors watch the Karyopharm (KPTI) webcast on December 10, 2025?

Watch the live webcast via the Investor "Events & Presentations" page at https://investors.karyopharm.com/events-presentations.

Will the Karyopharm (KPTI) fireside chat be available after the live event?

Yes. The webcast will be available for replay following the event on the same investor events page.

What is Dr. Claire Harrison’s role mentioned for the Karyopharm (KPTI) presentation?

Dr. Harrison is listed as Professor of Myeloproliferative Neoplasms and Clinical Director at Guy's and St. Thomas' NHS Foundation Trust and a leading expert in myelofibrosis.