Milestone Pharmaceuticals Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Rhea-AI Summary
Milestone Pharmaceuticals (Nasdaq: MIST) granted a total of 419,000 stock options as inducement awards to two new employees under its 2021 Inducement Plan.
The options were granted on February 2, 2026 with an exercise price of $1.96 per share (equal to the closing price). The awards vest over four years: 25% at the one-year anniversary, then monthly over 36 months, and are subject to continuous service and Plan terms. The grants were made pursuant to Nasdaq Listing Rule 5635(c)(4) and the Plan is reserved for inducement hires or rehires following non-employment.
Positive
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Negative
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News Market Reaction
On the day this news was published, MIST gained 0.51%, reflecting a mild positive market reaction.
Data tracked by StockTitan Argus on the day of publication.
Key Figures
Market Reality Check
Peers on Argus
While MIST was up 2.62%, key biotech peers were mixed to positive: ACOG +3.56%, GLSI +9%, KYTX +4.91%, and CYBN +0.12%, with VTYX flat. The move appears driven more by company-specific factors than a broad sector rotation.
Historical Context
| Date | Event | Sentiment | Move | Catalyst |
|---|---|---|---|---|
| Jan 26 | U.S. launch | Positive | -2.0% | Announced U.S. commercial availability of CARDAMYST nasal spray for PSVT. |
| Jan 06 | EMA filing | Positive | +1.5% | EMA accepted MAA for etripamil nasal spray for PSVT treatment in Europe. |
| Dec 17 | Device partner news | Positive | -3.3% | Aptar highlighted its Bidose system as delivery device for CARDAMYST. |
| Dec 12 | FDA approval | Positive | -18.3% | FDA approved CARDAMYST nasal spray as first self-administered PSVT treatment. |
| Dec 02 | Inducement grants | Neutral | -1.5% | Granted 30,000 stock options to new hires under inducement plan. |
Recent value-creating regulatory milestones for MIST, including FDA approval and U.S. launch of CARDAMYST, often saw muted or negative next-day price reactions, indicating a tendency for the stock to underreact or sell off on good news.
Over the past few months, Milestone progressed etripamil from FDA approval to U.S. commercial availability of CARDAMYST and EMA acceptance of a MAA in Europe, targeting patient populations over 2 million. Despite these milestones, price reactions to the Dec 12, 2025 FDA approval (-18.31%) and subsequent launch news (-2.02%) were negative. A prior inducement grant on Dec 2, 2025 also saw a small decline (-1.49%), suggesting today’s similar HR action fits an established pattern of limited trading impact.
Market Pulse Summary
This announcement details 419,000 stock options granted under Milestone’s 2021 Inducement Plan at an exercise price of $1.96, vesting over four years, as hiring-related incentives. It follows a series of transformative milestones, including FDA approval and U.S. launch of CARDAMYST and EMA acceptance of an etripamil MAA. Investors may watch how ongoing equity grants interact with existing insider awards and the company’s commercialization progress from its current $162.7M market valuation.
Key Terms
nasdaq listing rule 5635(c)(4) regulatory
inducement plan financial
exercise price financial
vesting commencement date financial
AI-generated analysis. Not financial advice.
MONTREAL and CHARLOTTE, N.C., Feb. 03, 2026 (GLOBE NEWSWIRE) -- Milestone Pharmaceuticals Inc. (Nasdaq: MIST) (the “Company” or “Milestone”), today announced that the Company granted equity awards, in the form of a total of 419,000 options (the “Options”) to purchase the Company’s common shares, pursuant to the Company’s 2021 Inducement Plan (the “Plan”), previously approved by the Company’s Compensation Committee and the Board of Directors, as a material inducement to the hiring of two new employees.
The Options have a grant date of February 2, 2026, and an exercise price of
The Option awards are subject to the award holder’s continuous service through each vesting date and to the terms and conditions of the Plan and its standard forms of grant agreements thereunder.
The foregoing equity award was granted as an inducement material to the employees entering into employment with Milestone, in accordance with Nasdaq Listing Rule 5635(c)(4). The Plan is used exclusively for the grant of equity awards to individuals who were not previously employees of Milestone, or following a bona fide period of non-employment, as an inducement material to such individuals’ entering into employment with Milestone, pursuant to Nasdaq Listing Rule 5635(c)(4).
About Milestone Pharmaceuticals
Milestone Pharmaceuticals Inc. (Nasdaq: MIST) is a biopharmaceutical company developing and commercializing innovative cardiovascular medicines to benefit people living with certain heart conditions. Milestone’s lead product is CARDAMYST™ (etripamil) nasal spray, a novel calcium channel blocker, which is FDA approved for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm in adults. Etripamil is also in development for the treatment of symptomatic episodic attacks associated with AFib-RVR.
Contact:
Kevin Gardner kgardner@lifesciadvisors.com