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A New Generation of Antidepressant Drug Precision Treatment Based on Revolutionary AI Technology is Born

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The9 (NCTY) investee WM Therapeutics Co., achieves breakthroughs in antidepressant drug precision treatment using GenAI technology. The new clinical trial results show significant progress in identifying effective subtypes for depression treatment, offering hope to patients worldwide.
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The announcement from WM Therapeutics regarding the clinical trial progress of a new generation antidepressant treatment can be a significant driver for The9 Limited's stock value. Investors tend to respond positively to advancements in clinical research, particularly in areas with high unmet medical needs such as depression. The reported statistical significance with a p-value of 0.004 indicates a high probability that the observed effects are not due to chance, which enhances the credibility of the trial results. This development could lead to a surge in investor confidence and potentially increase share prices in the short run. However, the impact on long-term value will depend on the drug's efficacy in broader clinical trials, regulatory approvals and market acceptance.

From a financial perspective, commercialization of the drug could lead to new revenue streams for The9 Limited, provided that WM Therapeutics can navigate the stringent regulation process. The cost of bringing a new drug to market is substantial and the financial backing from The9 could be important in supporting WM Therapeutics through this phase. The global antidepressant market is competitive, with several established players, so pricing strategy and marketing will be key factors in determining the financial impact of this new treatment.

WM Therapeutics' use of GenAI multi-dimensional omics technology represents a significant advancement in the field of personalized medicine for depression. The lack of progress over the past decade in antidepressant drug development has been a major concern within the medical community. This new approach, tailoring treatment to individual patients based on omics biomarkers, could revolutionize how depression is treated and lead to better patient outcomes. Biomarkers are objective measures that can indicate the presence or severity of a disease and their integration into treatment protocols can improve the precision of therapies.

The clinical trial's p-value suggests that the new treatment could be a substantial improvement over existing treatments, assuming the results can be replicated in larger populations. However, it should be noted that clinical trials often go through several phases and the results presented are from early-stage research. The data must be interpreted with caution until peer-reviewed and validated in larger, diverse populations.

SHANGHAI, April 15, 2024 /PRNewswire/ -- The9 Limited (Nasdaq: NCTY) ("The9"), an established Internet company, today announced that its investee WM Therapeutics Co., Ltd. (未名脑脑) ("WM Therapeutics") has achieved revolutionary breakthroughs in the proprietarily developed research and development of antidepressant drug precision treatment. WM Therapeutics' GenAI multi-dimensional omics drug clinical research technology has made significant progress in new clinical trial, bringing new hope to depression patients.

WM Therapeutics, a world-leading precision brain disease medical company based on GenAI and multi-dimensional omics biomarker technology, today announced its latest clinical trial results. This breakthrough research has made significant progress in depression drug research using multi-dimensional and multi-omics AI digital biomarkers. In a recently completed clinical trial, the platform successfully identified effective subtype in drug treatment of depression with a p-value of 0.004, which is significant in statistics. This indicated a profound understanding of depression patients and an innovation in future treatment options.

Over the past decade, there has been little progress in drug development for depression, leaving tens of thousands of patients suffering from this disease. WM Therapeutics' new technology not only indicated the birth of a new generation of precision antidepressant treatments, but also marked a major improvement over current treatments.

"This achievement not only demonstrates the capabilities of our powerful GenAI platform, but also brings new hope to patients with depression around the world. We are committed to extend the boundaries of science and technology to help patients suffering from the disease with scientific innovation," said Ms. Yan Gao, Founder and CEO of WM Therapeutics. Currently, the number of patients with depression worldwide is estimated to be approximately 3.8% of the population. This means approximately 280 million people worldwide are affected by depression. 5% of adults have depression problem. With the announcement of this result, WM Therapeutics hopes to accelerate the commercialization process of its antidepressant drug precision treatment and provide more effective treatment options for the global market.

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About Therapeutics Co., Ltd. (未名脑脑)

WM Therapeutics is a world-leading GenAI precision treatment company for brain diseases. It is developed based on AI multidimensional omics data analysis technology, GenAI and digital human technology, AI large language model driven drug discovery technology and brain-computer interface original research technology. The central nervous system (CNS) disease multi-dimensional multi-omics marker MDMMTM (Multi-dimensional Marker) algorithm platform builds brain disease digital targets and digital pathology based on a high-value, multi-dimensional omics database of millions of precise cohort studies of brain diseases (Digital PathologyTM) model, and personalized brain disease digital twins based on individual characteristics to achieve clinical precision diagnosis and treatment of central nervous system diseases (Precision CNS). Multidimensional and multi-omics markers include: Functional Biomarker IIPETM, Biological Marker IECETM, Cognitive & Behavior Biomarker PSNETM.

Core products include: GenAI large language model brain disease screening platform, AI precision diagnostic equipment, personalized neuromodulation treatment equipment, GenAI large language model digital human personalized psychological consultant and AI drug clinical research platform. Currently, in response to the huge unmet clinical needs, the pipeline under development covers depression, anxiety, Alzheimer's disease, bipolar disorder, autism, attention deficit and hyperactivity disorder, sleep disorders, pain, etc. and are at different clinical stages. Also, established partnerships have been made with world-renowned pharmaceutical companies and insurance companies.

About The9 Limited 

The9 Limited (The9) is an Internet company listed on Nasdaq in 2004. The9 aims to become a global diversified high-tech Internet company, and is engaged in blockchain business including the operation of cryptocurrency mining. The9 is also stepping into AI application business in different industries.

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SOURCE The9 Limited

FAQ

What technology did WM Therapeutics use for the breakthrough in antidepressant drug precision treatment?

WM Therapeutics used GenAI multi-dimensional omics drug clinical research technology for the breakthrough.

What was the p-value in the recently completed clinical trial for depression treatment?

The p-value in the clinical trial was 0.004, indicating significant statistical progress.

How many people worldwide are estimated to be affected by depression?

Approximately 280 million people worldwide are affected by depression, representing 3.8% of the population.

What is the goal of WM Therapeutics after the breakthrough in antidepressant drug precision treatment?

WM Therapeutics aims to accelerate the commercialization process of its treatment and provide more effective options for the global market.

The9 Limited American Depository Shares representing three class A ordinary shares

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The9 Ltd. is a Shanghai-based online game operator which had the exclusive licence to operate and distribute World of Warcraft in China, a licence it secured after successfully aiding Webzen Games with the distribution of Mu Online in China.