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NRx Pharmaceuticals (NASDAQ:NRXP) and HOPE Therapeutics to Present at NobleCon21 - Noble Capital Markets’ Twenty First Annual Emerging Growth Equity Conference

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NRx Pharmaceuticals (NASDAQ: NRXP) announced that Founder, Chairman, and CEO Jonathan Javitt, M.D., M.P.H. will present at NobleCon21 (Noble Capital Markets’ 21st Annual Emerging Growth Equity Conference) on Wednesday, December 3, 2025 at 4:30 PM ET in Boca Raton, FL.

The presentation will update the company’s expanded focus and progress across investigational drugs, medical devices, and interventional psychiatric therapies for suicidal depression, PTSD, and related conditions. The company noted it has begun generating clinical revenue and advanced drug development since NobleCon 2024.

Interested parties can register using discount code NRXPNOBLECON. A high-definition webcast will be posted the following day and archived for 90 days on the company site and on NobleCon and Channelchek.

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Positive

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Negative

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News Market Reaction

-2.45%
7 alerts
-2.45% News Effect
+10.8% Peak in 3 hr 17 min
-$2M Valuation Impact
$67M Market Cap
1.2x Rel. Volume

On the day this news was published, NRXP declined 2.45%, reflecting a moderate negative market reaction. Argus tracked a peak move of +10.8% during that session. Our momentum scanner triggered 7 alerts that day, indicating moderate trading interest and price volatility. This price movement removed approximately $2M from the company's valuation, bringing the market cap to $67M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Presentation time: 4:30 PM EST Webcast archive period: 90 days
2 metrics
Presentation time 4:30 PM EST NobleCon21 session on Wednesday, December 3
Webcast archive period 90 days Conference presentation webcast available on multiple sites

Market Reality Check

Price: $1.73 Vol: Volume 406,343 is slightl...
normal vol
$1.73 Last Close
Volume Volume 406,343 is slightly below the 20-day average of 467,798 ahead of the conference update. normal
Technical Shares at $2.20 are trading below the 200-day MA of $2.64, indicating a weaker longer-term trend into the event.

Peers on Argus

Biotech peers show mixed moves: VANI -6.08%, SLGL -3.86%, MGX -2.25%, while IMMX...

Biotech peers show mixed moves: VANI -6.08%, SLGL -3.86%, MGX -2.25%, while IMMX +8.21%. With NRXP down 5.96% and no broad peer momentum flagged, trading appears more stock-specific than sector-driven.

Historical Context

5 past events · Latest: Dec 03 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Dec 03 Pipeline expansion Positive +6.2% NRX-101 IND amended to add TMS augmentation indication with supportive data.
Dec 02 Regulatory milestone Positive -5.0% FDA receipt of KETAFREE ANDA with GDUFA goal date assigned.
Dec 02 Corporate update call Neutral -5.0% Announcement of conference call to review clinical, regulatory, operational items.
Dec 01 Conference appearance Positive -2.5% NobleCon21 presentation highlighting expanded focus and new clinical revenue.
Nov 17 Earnings and update Negative -15.3% Q3 2025 loss, limited cash, but initial revenue and pipeline/regulatory progress.
Pattern Detected

Recent news often triggers sharp moves, with mixed alignment: regulatory and earnings items saw both strong selloffs and rallies.

Recent Company History

Over the past months, NRx issued multiple updates spanning earnings, regulatory milestones, and corporate communications. Q3 2025 results showed a $4.0 million operating loss and initial revenue of about $240,000, alongside limited cash resources. Regulatory progress included KETAFREE™ ANDA steps and expanded NRX‑101 indications. Communication events such as conference appearances and update calls sometimes coincided with notable price swings, framing today’s NobleCon21 presentation as part of an ongoing effort to highlight the broader pipeline and new clinical revenue streams.

Regulatory & Risk Context

Active S-3 Shelf · $150 million
Shelf Active
Active S-3 Shelf Registration 2025-06-20
$150 million registered capacity

An effective Form S-3 shelf filed on June 20, 2025 would allow NRx to issue up to $150 million of various securities, providing flexibility to raise capital as needed but also creating potential dilution and leverage considerations for existing shareholders.

Market Pulse Summary

This announcement highlights NRx’s NobleCon21 presentation, emphasizing its expanded focus across in...
Analysis

This announcement highlights NRx’s NobleCon21 presentation, emphasizing its expanded focus across investigational drugs, medical devices, and interventional psychiatric therapies for suicidal depression and PTSD. It also notes that the company has begun generating clinical revenue since NobleCon 2024. Investors may track how these themes connect to recent regulatory steps, financial reports, and future capital-raising under the $150 million shelf when evaluating ongoing execution.

Key Terms

interventional psychiatry, ptsd
2 terms
interventional psychiatry medical
"HOPE Therapeutics, an interventional psychiatry network owned by NRx"
Interventional psychiatry is a medical specialty that treats severe or treatment-resistant mental health conditions using targeted procedures and fast-acting therapies, such as controlled brain stimulation or brief infusion treatments, rather than only daily pills and talk therapy. For investors it matters because these procedures require specialized equipment, trained clinics, regulatory approvals and reimbursement pathways, creating distinct markets and revenue streams and affecting a company’s commercial and regulatory risk—think of it as precision tools opening new business lines in mental health care.
ptsd medical
"therapies for suicidal depression, PTSD, and related conditions"
PTSD, or post-traumatic stress disorder, is a mental health condition that can develop after experiencing or witnessing a traumatic event, leading to ongoing feelings of fear, anxiety, or distress. For investors, understanding PTSD is important because widespread psychological impacts can influence market behavior, cause sudden shifts in confidence, or affect economic stability during times of collective trauma or crisis.

AI-generated analysis. Not financial advice.

WILMINGTON, Del., Dec. 01, 2025 (GLOBE NEWSWIRE) -- NRx Pharmaceuticals, Inc. (Nasdaq: NRXP, the “Company”, “NRx”), a clinical-stage biopharmaceutical company and HOPE Therapeutics, an interventional psychiatry network owned by NRx, today announced that its Founder, Chairman, and Chief Executive Officer, Jonathan Javitt, M.D., M.P.H will present at NobleCon21 - Noble Capital Markets’ Twenty First Annual Emerging Growth Equity Conference at Florida Atlantic University, Executive Education Complex, in Boca Raton, FL.- on Wednesday, December 3rd at 4:30 PM EST.

The presentation will provide an update on the Company’s expanded focus following progress achieved over the past year across investigational drugs, medical devices, and interventional psychiatric therapies for suicidal depression, PTSD, and related conditions. As previously announced, the Company has begun generating clinical revenue and has made meaningful progress in drug development since its appearance at NobleCon 2024.

Interested investors and guests of the Company are welcome to attend at a discounted rate. Please register here using the discount code NRXPNOBLECON.

A high-definition video webcast of the presentation will be available the following day on the Company's website https://ir.nrxpharma.com/events, and as part of a complete catalog of presentations available at Noble Capital Markets’ Conference website: www.nobleconference.com and on Channelchek www.channelchek.com, the investor portal created by Noble. The webcast will be archived on the company's website, the NobleCon website, and on Channelchek.com for 90 days following the event. 

About NRx Pharmaceuticals, Inc.
NRx Pharmaceuticals, Inc. (www.nrxpharma.com), is a clinical-stage biopharmaceutical company focused on Neuroplastic Therapies for the treatment of central nervous system disorders, specifically suicidal depression, PTSD, anxiety, and Autism. The Company combines drug development with a best-in-class network of clinics (HOPE Therapeutics) offering medication management, Transcranial Magnetic Stimulation, and Hyperbaric Oxygen Therapy that combine to achieve rapid response and remission. NRx is developing NRX-100 (preservative-free intravenous ketamine) and NRX-101, (oral D-cycloserine/lurasidone). NRX-100 has been awarded Fast Track Designation for the treatment of Suicidal ideation in Depression, including Bipolar Depression. NRX-101 has been awarded Breakthrough Therapy Designation for the treatment of suicidal bipolar depression. NRx has filed an Abbreviated New Drug Application for its preservative-free ketamine formulation and is anticipating a July 2026 launch.

About HOPE Therapeutics, Inc.
HOPE Therapeutics, Inc. (www.hopetherapeutics.com), a subsidiary of NRx Pharmaceuticals, is a healthcare delivery company that is building a best-in-class network of interventional psychiatry clinics to offer ketamine and other neuroplastic medications, transcranial magnetics stimulation (TMS), Hyperbaric Oxygen Therapy, and other lifesaving therapies to patients with suicidal depression and related disorders, together with a digital therapeutic-enabled platform designed to augment and preserve the clinical benefit of NMDA-targeted drug therapy. HOPE is the first network in Florida to offer the AMPA One Day (ONE-D) treatment that combines TMS, physician-prescribed D-cycloserine, and lisdexamfetamine to achieve remission from treatment resistant depression.

About Noble Capital Markets, Inc.
Established in 1984, Noble Capital Markets (Noble) is an SEC / FINRA registered full-service broker-dealer offering investment/merchant banking and advisory services, with an award-winning research team, and a proprietary research distribution platform (Channelchek). Noble provides middle-market expertise to entrepreneurs, corporations, financial sponsors, and investors. In addition to its large scale in-person conference, NobleCon, Noble hosts multi-sector virtual conferences throughout the year. Over the more than 40 years, Noble has raised billions of dollars for companies and published more than 45,000 equity research reports. www.noblecapitalmarkets.com | www.nobleconference.com.

About Channelchek
Noble launched www.channelchek.com in 2018 – an investor community dedicated exclusively to emerging growth public companies and their industries. Channelchek is the first service to offer institutional-quality, FINRA-regulated research to the public, for FREE at every level without a subscription. With more than 7,000 public companies listed on the site, content includes advanced market data, equity research, videos & webcasts, and industry articles.

Notice Regarding Forward-Looking Statements
The information contained herein includes forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and Section 27A of the Securities Act of 1933, as amended. Forward-looking statements generally include statements that are predictive in nature and depend upon or refer to future events or conditions, and include words such as "may," "will," "should," "would," "expect," "plan," "believe," "intend," "look forward," and other similar expressions among others. These statements relate to future events or to the Company's future financial performance, and involve known and unknown risks, uncertainties and other factors that may cause the Company's actual results to be materially different from any future results, levels of activity, performance or achievements expressed or implied by these forward-looking statements. The Company has reported regulatory milestones as they have been achieved but has not predicted the outcome of any future regulatory determination. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. Any forward-looking statement reflects the Company's current views with respect to future events and is subject to these and other risks, including uncertainties and assumptions relating to the Company's operations, results of operations, growth strategy, and, among other things, liquidity. More detailed information about the Company and the risk factors that may affect the realization of forward-looking statements is set forth in the Company's most recent Annual Report on Form 10-K and other filings with the Securities and Exchange Commission. Investors and security holders are urged to read these documents free of charge on the SEC's website at http://www.sec.gov. Except as may be required by applicable law, the Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, whether as a result of new information, future events or otherwise.

For further information:
Matthew Duffy
Co-CEO, Hope Therapeutics, Inc.
Chief Business Officer, NRx Pharmaceuticals, Inc.
mduffy@nrxpharma.com

Brian Korb

Managing Partner, astr partners
(917) 653-5122
brian.korb@astrpartners.com
  



FAQ

When will NRx Pharmaceuticals (NRXP) present at NobleCon21?

NRx will present on Wednesday, December 3, 2025 at 4:30 PM ET at Florida Atlantic University in Boca Raton, FL.

Who from NRx (NRXP) is presenting at NobleCon21?

Founder, Chairman, and CEO Jonathan Javitt, M.D., M.P.H. will deliver the presentation.

What topics will NRx (NRXP) cover in its NobleCon21 presentation?

The presentation will update progress on investigational drugs, medical devices, and interventional psychiatric therapies for suicidal depression, PTSD, and related conditions.

How can investors register to attend the NRXP presentation at NobleCon21?

Investors can register with the discount code NRXPNOBLECON; interested guests were invited to register via the conference registration link.

Will there be a webcast of the NRXP NobleCon21 presentation and where will it be posted?

A high-definition webcast will be available the following day and archived for 90 days on the company website, NobleCon website, and Channelchek.

Has NRx (NRXP) reported any revenue or development progress ahead of NobleCon21?

The company said it has begun generating clinical revenue and made meaningful drug development progress since NobleCon 2024.
Nrx Pharmaceuticals Inc

NASDAQ:NRXP

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53.88M
26.86M
11.55%
25.47%
2.66%
Biotechnology
Pharmaceutical Preparations
Link
United States
WILMINGTON