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New Survey Shows Management of Blood Clots is Inconsistent, Even for Patients with the Same Risk Profile

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Penumbra (NYSE:PEN) and several leading medical organizations announced findings from a comprehensive survey on venous thromboembolism (VTE) care management through their 'Get Out the Clot' campaign. The survey of nearly 270 healthcare professionals revealed significant inconsistencies in blood clot treatment protocols.

Key findings show that only 56% of interventional physicians believe their protocols provide clear direction for pulmonary embolism (PE) risk management, while just 39% feel protocols are clear for deep vein thrombosis (DVT) treatment. Notably, 73% of interventional physicians want expanded use of thrombectomy and computer-assisted vacuum thrombectomy (CAVT) at their hospitals for PE patients, citing benefits like reduced ICU stays (57%) and improved hemodynamics (55%).

The survey also highlighted that more than half of institutions lack formal response teams, and only 35% of physicians report treatment decisions are made by specialty consensus, indicating significant room for improvement in collaborative care approaches.

Penumbra (NYSE:PEN) e diverse importanti organizzazioni mediche hanno presentato i risultati di un ampio sondaggio sulla gestione della tromboembolia venosa (VTE) nell'ambito della loro 'Get Out the Clot' campaign. Il sondaggio, condotto su quasi 270 operatori sanitari, ha messo in luce notevoli incoerenze nei protocolli di trattamento dei coaguli di sangue.

I principali risultati mostrano che solo il 56% dei medici interventisti ritiene che i protocolli forniscano indicazioni chiare per la gestione del rischio di embolia polmonare (PE), mentre appena il 39% li considera chiari per il trattamento della trombosi venosa profonda (DVT). È significativo che il 73% dei medici interventisti desideri un uso più esteso della trombectomia e della trombectomia con aspirazione assistita da computer (CAVT) nei loro ospedali per i pazienti con PE, citando vantaggi come la riduzione delle degenze in terapia intensiva (57%) e il miglioramento dell'emodinamica (55%).

Il sondaggio ha inoltre evidenziato che più della metà delle strutture non dispone di team di risposta formali e che solo il 35% dei medici riferisce che le decisioni terapeutiche vengono prese per consenso tra le specialità, indicando ampi margini di miglioramento negli approcci di cura collaborativa.

Penumbra (NYSE:PEN) y varias organizaciones médicas líderes dieron a conocer los resultados de una encuesta exhaustiva sobre la gestión del tromboembolismo venoso (VTE) dentro de su 'Get Out the Clot' campaign. La encuesta a casi 270 profesionales de la salud reveló inconsistencias significativas en los protocolos de tratamiento de los coágulos sanguíneos.

Los hallazgos principales muestran que solo el 56% de los médicos intervencionistas considera que sus protocolos ofrecen indicaciones claras para la gestión del riesgo de embolia pulmonar (PE), mientras que apenas el 39% cree que los protocolos son claros para el tratamiento de la trombosis venosa profunda (DVT). Cabe destacar que el 73% de los médicos intervencionistas desea ampliar el uso de la trombectomía y la trombectomía asistida por vacío asistido por ordenador (CAVT) en sus hospitales para pacientes con PE, citando beneficios como la reducción de estancias en la UCI (57%) y la mejora de la hemodinámica (55%).

La encuesta también subrayó que más de la mitad de las instituciones carecen de equipos de respuesta formales y que solo el 35% de los médicos informa que las decisiones de tratamiento se toman por consenso entre especialidades, lo que indica un margen considerable de mejora en los enfoques de atención colaborativa.

Penumbra (NYSE:PEN)와 여러 주요 의학 단체들이 'Get Out the Clot' campaign을 통해 정맥 혈전 색전증(VTE) 치료 관리에 대한 종합 설문조사 결과를 발표했습니다. 거의 270명의 의료 전문가를 대상으로 한 이 설문조사에서는 혈전 치료 프로토콜에 상당한 불일치가 있는 것으로 나타났습니다.

주요 결과에 따르면 중재 의사의 56%만이 자신의 프로토콜이 폐색전증(PE) 위험 관리를 위한 명확한 지침을 제공한다고 생각하며, 심부정맥혈전증(DVT) 치료에 대해 명확하다고 느끼는 비율은 겨우 39%였습니다. 특히 중재 의사의 73%는 PE 환자에 대해 병원에서 혈전제거술 및 컴퓨터 보조 진공 혈전제거술(CAVT)의 사용을 확대하기를 원했으며, 중환자실 입원 기간 단축(57%) 및 혈역학 개선(55%) 등의 이점을 언급했습니다.

설문은 또한 절반 이상의 기관이 공식 대응 팀을 갖추지 못했고, 치료 결정이 전문과 간 합의로 이루어진다고 보고한 의사는 단지 35%에 불과하다는 점을 강조해 협력적 치료 접근 방식에서 개선 여지가 큼을 나타냈습니다.

Penumbra (NYSE:PEN) et plusieurs organisations médicales de premier plan ont annoncé les résultats d'une enquête approfondie sur la prise en charge de la thromboembolie veineuse (VTE) dans le cadre de leur 'Get Out the Clot' campaign. L'enquête menée auprès de près de 270 professionnels de santé a révélé des incohérences marquées dans les protocoles de traitement des caillots sanguins.

Les constatations clés montrent que seulement 56 % des médecins interventionnels estiment que leurs protocoles fournissent des directives claires pour la gestion du risque d'embolie pulmonaire (PE), tandis que seulement 39 % jugent les protocoles clairs pour le traitement de la thrombose veineuse profonde (DVT). Fait notable, 73 % des médecins interventionnels souhaitent étendre l'utilisation de la thrombectomie et de la thrombectomie assistée par aspiration informatisée (CAVT) dans leurs hôpitaux pour les patients atteints de PE, citant des avantages tels que la réduction des séjours en soins intensifs (57 %) et l'amélioration de l'hémodynamique (55 %).

L'enquête a également souligné que plus de la moitié des établissements ne disposent pas d'équipes de réponse formelles et que seulement 35 % des médecins déclarent que les décisions de traitement sont prises par consensus entre spécialités, ce qui indique une marge importante d'amélioration des approches de soins collaboratifs.

Penumbra (NYSE:PEN) und mehrere führende medizinische Organisationen haben Ergebnisse einer umfassenden Umfrage zur Versorgung bei venöser Thromboembolie (VTE) im Rahmen ihrer 'Get Out the Clot' campaign vorgestellt. Die Befragung von fast 270 Gesundheitsfachkräften zeigte bedeutende Uneinheitlichkeiten in den Behandlungsprotokollen für Blutgerinnsel.

Zentrale Ergebnisse zeigen, dass nur 56% der interventionellen Ärzte der Ansicht sind, ihre Protokolle gäben klare Vorgaben zur Risikosteuerung bei Lungenembolie (PE), während lediglich 39% die Protokolle für die Behandlung tiefer Venenthrombosen (DVT) als klar erachten. Bemerkenswert ist, dass 73% der interventionellen Ärzte eine stärkere Nutzung von Thrombektomie und computerassistierter Vakuum-Thrombektomie (CAVT) an ihren Kliniken für PE-Patienten befürworten und Vorteile wie verkürzte Intensivaufenthalte (57%) und verbesserte Hämodynamik (55%) anführen.

Die Umfrage hob außerdem hervor, dass in mehr als der Hälfte der Einrichtungen formale Notfallteams fehlen und dass nur 35% der Ärzte berichten, dass Therapieentscheidungen konsensual über Fachdisziplinen getroffen werden — ein deutliches Indiz für Verbesserungsbedarf bei kooperativen Behandlungsansätzen.

Positive
  • 73% of interventional physicians support expanded use of advanced treatments like thrombectomy and CAVT
  • Strong collaboration between leading medical organizations in addressing VTE care gaps
  • Survey identifies clear opportunities for care standardization and improvement
Negative
  • Only 56% of physicians report clear protocols for PE risk management
  • Just 39% have clear protocols for DVT treatment
  • More than 50% of institutions lack formal response teams
  • Only 35% of treatment decisions are made by specialty consensus

Survey Conducted by the Get Out the Clot Campaign, an Initiative Focused on Identifying and Closing Gaps in Patient Care for Blood Clots

ALAMEDA, Calif., Sept. 9, 2025 /PRNewswire/ -- The American Venous Forum (AVF), International Society on Thrombosis and Haemostasis (ISTH), National Blood Clot Alliance (NBCA), Penumbra (NYSE: PEN), The PERT Consortium® and Society for Vascular Medicine (SVM), which have come together to form the Get Out the Clot campaign, today announced findings from a new survey assessing the current state of venous thromboembolism (VTE) care, also known as blood clots in the body. Get Out the Clot is a collaborative educational initiative to help identify gaps in patient care related to blood clot conditions, including standardizing care and expanding access to the latest innovations to improve patient outcomes.

"The 'Get Out the Clot' collaborative campaign unites the expertise and resources of leaders in the field of thrombosis and hemostasis to raise global awareness, foster innovation and ultimately improve outcomes for individuals affected by blood clot conditions," said ISTH President Pantep Angchaisuksiri, M.D.

The survey, which included nearly 270 healthcare professionals, both interventional physicians (those who perform minimally invasive procedures) and non-interventional physicians (those who manage and treat blood clots using non-invasive methods) caring for VTE patients, found that:

  • Only 56% of interventional physicians surveyed believe their protocols provide clear direction based on pulmonary embolism (PE) risk beyond medical management and approaches vary, even for patients with the same risk profile. Further, only 39% of interventional physicians surveyed believe that their protocols provide clear direction for deep vein thrombosis (DVT) treatment beyond medical management, and approaches vary across patient types.
  • Interventional physicians stated in the survey that they prefer newer treatment options such as mechanical thrombectomy, including computer assisted vacuum thrombectomy (CAVT), in combination with anticoagulation for 33% of their high risk and 37% of their intermediate-high risk PE patients. For intermediate-low and low-risk patients, most preferred anticoagulation alone. 
  • Nearly half of DVT patients are treated with anticoagulation alone. However, 71% of interventionalists surveyed state that they would like to see their hospital expand use of thrombectomy for DVT.

VTE affects up to 900,000 Americans annually, leading to approximately 100,000 deaths.[1] VTE encompasses deep vein thrombosis (DVT, where a clot forms in a deep vein) and pulmonary embolism (PE, which is a clot that blocks the arteries in the lungs). Unfortunately, there are significant gaps and discrepancies in caring for these thrombus conditions, such as with PE, where there are often delays in care (up to 26% of cases in one study) and misdiagnosis (up to 53% of patients in one study).[2],[3]

"The complexity of pulmonary embolism treatment cannot be overstated," said Herbert Aronow, M.D., MPH, Past President, Society for Vascular Medicine. "PE can be difficult to diagnose and, in many cases, if not treated quickly, can be life-threatening. Early identification is critical, and institutions must have a streamlined process to evaluate and treat patients."

Collaborating to Meet Patient Needs
Collaboration and communication among physicians are crucial in determining the most effective care paths for patients, especially in complex conditions like VTE.

"Blood clots are often complex and the symptoms easily overlooked by both patients and healthcare providers, as symptoms can mimic other non-life-threatening medical conditions," said Leslie Lake, volunteer president of the National Blood Clot Alliance. "These survey results provide a vital opportunity to highlight critical information and identify appropriate support across the healthcare system to improve care and outcomes."

More than half of physicians surveyed report that they do not have a formal response team (e.g., a pulmonary embolism response team (PERT), or a venous thromboembolism response team) at their institution. Formal response teams streamline care through a collaborative multidisciplinary approach by engaging experts with the knowledge of and access to a broad spectrum of resources and procedures, potentially improving patient outcomes.

Additionally, only 35% of physicians surveyed perceive the ultimate treatment decision is made by consensus among specialties, showcasing that collaboration amongst physicians continues to be limited.

"The gaps and discrepancies in VTE care demonstrate why it is critical that health systems across the U.S. standardize care through collaboration among medical specialties," said Rachel Rosovsky, M.D., MPH, Immediate Past President, The PERT Consortium.® "Studies have demonstrated that the formation of PERTs helps facilitate prompt diagnosis and the implementation of appropriate treatments in a judicious manner, leading to advancements in care, such as reducing the time to therapeutic anticoagulation – an essential aspect in PE care. Through PERTs and the adoption of efficient and effective practices, we can improve patient care and outcomes and ensure consistency of appropriate medical treatment across diverse patient populations."

The Next Phase of VTE Care
"Collaboration, innovation, and education will be the driving forces behind improving patient outcomes and providing consistent, high-quality care for all those affected by venous thromboembolism," said Mark D. Iafraiti, M.D., President Elect, the American Venous Forum. "By focusing on these priorities, we can create a more unified approach to VTE care, ensuring that patients receive timely, accurate diagnoses and the most effective care options available."

Nearly three-quarters (73%) of interventional physicians want to see expanded use of thrombectomy and CAVT at their hospitals for PE patients. These physicians believe the benefits of newer procedures, such as mechanical thrombectomy and CAVT, can improve patient outcomes, including minimizing ICU stays (57%) and rapidly improving hemodynamics (55%).

To achieve their goal of expanding use of thrombectomy in PE, the physicians surveyed believe their hospital would benefit from having more providers trained in these techniques.

"This survey sheds light on critical aspects of the current state of VTE care and the many opportunities to better align management protocols across the U.S. to work towards improving patient care," said James F. Benenati, M.D., FSIR, chief medical officer at Penumbra, the world's leading thrombectomy company. "At Penumbra, our focus is to continue to advance VTE care with technologies like CAVT, which has shown meaningful benefits on patient outcomes and the overall health systems."

To learn more about the survey and to help raise awareness of VTE symptoms and care options, visit www.GetOutTheClot.com.

About the Survey
The Get Out the Clot Survey was an online, quantitative opinion survey conducted by the American Venous Forum, International Society on Thrombosis and Haemostasis, National Blood Clot Alliance, Penumbra, The PERT Consortium® and the Society for Vascular Medicine. The survey was fielded between October and November 2024 and included responses from 269 healthcare professionals (HCPs; 143 of whom were interventionalist physicians and 126 of whom were non-interventionalist physicians) treating patients with venous thromboembolism (VTE) including both pulmonary embolism (PE) and deep vein thrombosis (DVT).

About Get Out the Clot
Get Out the Clot is a collaborative educational initiative uniting experts in venous thromboembolism (VTE) care to help identify gaps in patient care related to blood clot conditions, including standardizing care and expanding access to the latest innovations to improve patient outcomes. The campaign is led by the American Venous Forum, the International Society on Thrombosis and Haemostasis, National Blood Clot Alliance, Penumbra, The PERT Consortium®, and the Society for Vascular Medicine. The organizations involved with Get Out the Clot believe it is critical that health systems across the United States establish a standard of care for thrombotic conditions to help patients get diagnosed promptly and receive the most appropriate care. For more information about Get Out the Clot, visit GetOutTheClot.com.

About the American Venous Forum (AVF)
We are a diverse, dynamic, global organization committed to improving the care of those with venous and lymphatic disease. Our multi-specialty, multi-disciplinary membership of physicians, researchers and advanced practice providers embrace core values of integrity, inclusion, and scientific excellence in research. Those values drive us to provide increasingly quality care and seek ongoing improvement every day. www.venousforum.org  

About the International Society on Thrombosis and Haemostasis (ISTH)
Founded in 1969, the ISTH is the leading international medical and scientific professional organization dedicated to advancing the understanding, prevention, diagnosis and treatment of conditions related to thrombosis and hemostasis. The ISTH professional membership community includes more than 7,000 clinicians, researchers and educators from more than 120 countries working together to advance science and improve clinical care around the world. Among its highly-regarded activities and initiatives are education and standardization programs, research activities, meetings and congresses, clinical and laboratory practice guidance and guidelines, peer-reviewed publications, expert committees and World Thrombosis Day on 13 October. Learn more at www.isth.org.

About National Blood Clot Alliance 
Founded in 2003, the National Blood Clot Alliance (NBCA) is the premier not-for-profit organization in the United States dedicated to advancing the prevention, early diagnosis, and successful treatment of life-threatening venous blood clots. NBCA brings together patients, caregivers, healthcare professionals, and advocates to raise awareness and improve the quality of care for those affected by blood clots. With a focus on education, advocacy, and patient support, NBCA's initiatives include patient-centered research collaborations, public awareness campaigns, peer support networks, and comprehensive VTE education. Learn more at www.stoptheclot.org.

About Penumbra 
Penumbra, Inc., the world's leading thrombectomy company, is focused on developing the most innovative technologies for challenging medical conditions such as ischemic stroke, venous thromboembolism such as pulmonary embolism, and acute limb ischemia. Its broad portfolio, which includes computer assisted vacuum thrombectomy (CAVT), centers on removing blood clots from head-to-toe with speed, safety and simplicity. By pioneering these innovations, Penumbra supports healthcare providers, hospitals and clinics in more than 100 countries, working to improve patient outcomes and quality of life. For more information, visit www.penumbrainc.com and connect on InstagramLinkedIn and X.

About The PERT Consortium® 
The purpose of The PERT Consortium®  is to serve the general public by undertaking activities to advance the status of PE care and promote research in the treatment of pulmonary embolism. Specifically, the Consortium's purpose is to:

Promote the adoption of the PERT model in healthcare institutions across the United States to ensure the prompt diagnosis and treatment of pulmonary embolism.

Expand the current body of scientific literature on the diagnosis and treatment of pulmonary embolism through the funding of scientific endeavors.

Educate the general public and healthcare professionals regarding pulmonary embolism diagnosis, treatment, and care.

By focusing solely on the entity of pulmonary embolism – its etiology, pathophysiology, prevention, management approach, outcomes of specific treatments, and follow-up pathways – it is the intention of the Consortium to increase awareness of treatment options available to patients with PE, to reduce its incidence worldwide, to improve health outcomes, and to positively influence the impact of this terrible disease.

About the Society for Vascular Medicine
The Society for Vascular Medicine is a professional organization that aims to improve the integration of vascular biological advances into medical practice and to maintain high standards of clinical vascular medicine. The Society is distinguished by its emphasis on clinical approaches to vascular disorders. Optimal vascular care is best accomplished by the collegial interaction of a community of vascular professionals, including individuals with expertise in vascular medicine, vascular surgery, interventional radiology, vascular nursing, vascular technology, and other disciplines. The Society recognizes the importance of individuals with diverse backgrounds in achieving ideal standards of research and clinical practice. The Society encourages these individuals to join the Society and to help accomplish its clinical and scientific mission.

Contact




Jennifer Heth

Parinaz Farzin

Penumbra, Inc.

Merryman Communications

jheth@penumbrainc.com

parinaz@merrymancommunications.com

510-995-9791

310.600.6746

1 Centers for Disease Control and Prevention. (2023, June). Impact of Blood Clots on the United States Infographic. National Center on Birth Defects and Developmental Disabilities (NCBDDD). https://www.cdc.gov/blood-clots/toolkit/impact-of-blood-clots.html?CDC_AAref_Val=https://www.cdc.gov/ncbddd/dvt/infographic-impact.html. Accessed July 9, 2024.
Chun Shing Kwok, Chun Wai Wong, Saul Lovatt, Phyo K Myint, Yoon K Loke, Misdiagnosis of pulmonary embolism and missed pulmonary embolism: A systematic review of the literature, Health Sciences Review, Volume 3, 2022, 100022, ISSN 2772-6320, https://doi.org/10.1016/j.hsr.2022.100022.
(https://www.sciencedirect.com/science/article/pii/S2772632022000113)
3 Hendriksen JM;Koster-van Ree M;Morgenstern MJ;Oudega R;Schutgens RE;Moons KG;Geersing GJ; (2017, March). Clinical characteristics associated with diagnostic delay of pulmonary embolism in primary care: A retrospective observational study. BMJ open. https://pubmed.ncbi.nlm.nih.gov/28279993/

 

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SOURCE Get Out the Clot

FAQ

What are the key findings of Penumbra's (PEN) Get Out the Clot campaign survey in 2025?

The survey revealed that only 56% of interventional physicians have clear PE protocols, 39% have clear DVT protocols, and 73% want expanded use of thrombectomy and CAVT treatments. More than half of institutions lack formal response teams.

How many healthcare professionals participated in Penumbra's VTE care survey?

The survey included nearly 270 healthcare professionals, including both interventional and non-interventional physicians who care for VTE patients.

What percentage of interventional physicians want expanded use of thrombectomy at Penumbra (PEN)?

73% of interventional physicians want to see expanded use of thrombectomy and CAVT at their hospitals for PE patients, citing benefits like reduced ICU stays and improved hemodynamics.

What are the current challenges in VTE treatment according to Penumbra's survey?

Key challenges include inconsistent treatment protocols, lack of formal response teams in over 50% of institutions, limited consensus-based decision making (35%), and varying approaches even for patients with similar risk profiles.

How many Americans are affected by VTE annually according to the study?

VTE affects up to 900,000 Americans annually, resulting in approximately 100,000 deaths.
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