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Predictive Oncology Completes Sale of Skyline Medical Assets to DeRoyal Industries

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Predictive Oncology (NASDAQ: POAI) has completed the sale of its Skyline Medical subsidiary's assets to DeRoyal Industries, a global medical products manufacturer. The transaction involves the STREAMWAY® System, an FDA-cleared direct-to-drain wall suction waste fluid management technology.

The sale aligns with POAI's strategic focus on AI-driven drug discovery and comes ahead of its planned merger with Renovaro Biosciences. The company had implemented a restructuring plan for Skyline Medical in late 2023, successfully returning the unit to profitability by the end of 2024.

DeRoyal Industries will integrate the STREAMWAY® System into its product portfolio under its own brand, maintaining service continuity for existing customers while expanding market reach. The system provides healthcare professionals with an automated solution for managing potentially hazardous fluids during medical procedures, designed to reduce manual handling and eliminate spillage risks.

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Positive

  • Successfully restructured and returned Skyline Medical to profitability by end of 2024
  • Strategic divestment allows focus on core AI-driven drug discovery business
  • Asset sale to established market leader DeRoyal Industries enhances product distribution potential

Negative

  • Reduction in business diversification with the sale of revenue-generating subsidiary

News Market Reaction – POAI

-2.65%
-2.65% Session move

In the trading session that priced this news, POAI declined 2.65%, reflecting a moderate negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

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Deal positions STREAMWAY® Systems with an established market leader to drive accelerating growth

Transaction allows Predictive Oncology to be highly focused on its core AI-driven drug discovery capabilities and integrate seamlessly with Renovaro Biosciences

PITTSBURGH, March 20, 2025 (GLOBE NEWSWIRE) -- Predictive Oncology Inc. (NASDAQ: POAI), a leader in AI-driven drug discovery, announced today that it has completed the sale of assets related to its wholly owned subsidiary, Skyline Medical Inc., to DeRoyal Industries, Inc., a global manufacturer and supplier of medical products.

As previously disclosed, Skyline Medical’s business operated outside the core focus of Predictive Oncology, which is the use of artificial intelligence and machine learning to expedite early drug discovery and enable drug development for the benefit of cancer patients. This transaction was consummated in anticipation of Predictive Oncology’s previously announced merger with Renovaro Biosciences.

Headquartered in Eagan, Minnesota, Skyline Medical markets and sells the FDA-cleared STREAMWAY® System, a direct-to-drain wall suction waste fluid management technology that provides healthcare professionals with an automated, secure, and reliable method for managing potentially hazardous fluids, such as those generated during surgeries or other medical procedures. The system is designed to reduce manual handling, eliminate fluid spillage risks, and streamline waste management operations within medical settings.

“In late 2023, we implemented a restructuring plan with Skyline Medical to dramatically improve its operating metrics and return the business unit to profitability,” stated Josh Blacher, Chief Financial Officer of Predictive Oncology. “Having largely achieved this goal by the end of 2024, we then looked to consummate a synergistic business combination with an industry leader that would enable Skyline Medical to reach its full potential. That is exactly what this transaction with DeRoyal represents.”

"We are excited to integrate this innovative wall suction waste fluid management system into our product offerings," said Chris Schulze, Chief Sales Officer of DeRoyal Industries. "This acquisition strengthens our position as a leader in healthcare waste management solutions, enabling us to better serve our customers with advanced, environmentally friendly technologies. The Streamway® product line aligns with DeRoyal’s commitment to improving the safety, efficiency, and sustainability of healthcare facilities, while also supporting their efforts to meet regulatory compliance standards."

As part of the acquisition, DeRoyal Industries will offer the Streamway® wall suction waste fluid management product line under the DeRoyal brand. This transition will ensure seamless continuity for Skyline Medical’s existing customers while expanding the product's reach to new healthcare facilities looking to enhance their fluid waste management systems. The transaction was accounted for as an asset sale and all necessary approvals have been previously obtained.

About Predictive Oncology
Predictive Oncology is on the cutting edge of the rapidly growing use of artificial intelligence and machine learning to expedite early drug discovery and enable drug development for the benefit of cancer patients worldwide. The company’s scientifically validated AI platform, PEDAL, is able to predict with 92% accuracy if a tumor sample will respond to a certain drug compound, allowing for a more informed selection of drug/tumor type combinations for subsequent in-vitro testing. Together with the company’s vast biobank of more than 150,000 assay-capable heterogenous human tumor samples, Predictive Oncology offers its academic and industry partners one of the industry’s broadest AI-based drug discovery solutions, further complimented by its wholly owned CLIA laboratory facility. Predictive Oncology is headquartered in Pittsburgh, PA.

About DeRoyal Industries
DeRoyal Industries, Inc. is a leading manufacturer and supplier of innovative healthcare products and services. For over 50 years, DeRoyal has been dedicated to providing high-quality solutions that improve patient outcomes, enhance the efficiency of healthcare providers, and support the success of healthcare facilities worldwide. The company offers a wide range of products including surgical, wound care, infection prevention, and waste management solutions.

Investor Relations Contact:
Michael Moyer
LifeSci Advisors, LLC
mmoyer@lifesciadvisors.com

Forward-Looking Statements:
Certain matters discussed in this release contain forward-looking statements. These forward-looking statements reflect our current expectations and projections about future events and are subject to substantial risks, uncertainties and assumptions about our operations and the investments we make. All statements, other than statements of historical facts, included in this press release regarding our strategy, future operations, future financial position, future revenue and financial performance, projected costs, prospects, changes in management, plans and objectives of management are forward-looking statements. The words “anticipate,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “would,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Our actual future performance may materially differ from that contemplated by the forward-looking statements as a result of a variety of factors including, among other things, factors discussed under the heading “Risk Factors” in our filings with the SEC. Except as expressly required by law, the company disclaims any intent or obligation to update these forward-looking statements.


FAQ

What assets did Predictive Oncology (POAI) sell to DeRoyal Industries?

POAI sold its Skyline Medical subsidiary's assets, including the FDA-cleared STREAMWAY® System, a direct-to-drain wall suction waste fluid management technology.

How did POAI's restructuring of Skyline Medical in 2023 perform?

The restructuring plan implemented in late 2023 successfully achieved its goal, returning Skyline Medical to profitability by the end of 2024.

What will happen to existing Skyline Medical customers after the DeRoyal acquisition?

DeRoyal Industries will continue offering the Streamway® product line under their brand, ensuring seamless service continuity for existing customers.

How does the Skyline Medical sale align with POAI's business strategy?

The sale allows POAI to focus on its core AI-driven drug discovery capabilities and integrate with Renovaro Biosciences in their planned merger.