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Renovaro Launches AI-Based Neurotoxin Countermeasure Initiative Addressing Emerging National Security Needs

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Renovaro Inc. (NASDAQ:RENB) has announced the launch of an AI-based zebrafish screening platform through its subsidiary BioSymetrics, designed to identify medical countermeasures for neurotoxic chemical agents. The platform, integrated into Renovaro's Defense Countermeasures Program, represents the company's strategic entry into biotechnology and biodefense.

The company's platform features advanced data preprocessing and in vivo toxicity testing, capable of screening over 1,000 compounds per week. This development is supported by a newly announced patent for "Methods, Systems, and Frameworks for Unbiased Data in Drug Discovery Predictions," strengthening Renovaro's intellectual property portfolio.

The platform captures behavioral, cardiovascular, and muscular responses to neuroactive chemicals, enabling machine learning-driven compound triage and mechanism of action prediction. This technology serves both commercial CNS drug discovery and defense applications, particularly focusing on countermeasures against weaponized substances like Sarin.

Renovaro Inc. (NASDAQ:RENB) ha annunciato il lancio di una piattaforma di screening basata su intelligenza artificiale per zebrafish, tramite la sua controllata BioSymetrics, progettata per identificare contromisure mediche contro agenti chimici neurotossici. Questa piattaforma, integrata nel Programma di Contromisure per la Difesa di Renovaro, segna l'ingresso strategico dell'azienda nel settore della biotecnologia e della biodefesa.

La piattaforma dell'azienda offre avanzate tecniche di preprocessamento dei dati e test di tossicità in vivo, con la capacità di analizzare oltre 1.000 composti a settimana. Questo progresso è supportato da un brevetto recentemente annunciato intitolato "Metodi, Sistemi e Strutture per Dati Non Distorti nelle Previsioni di Scoperta di Farmaci", che rafforza il portafoglio di proprietà intellettuale di Renovaro.

La piattaforma rileva risposte comportamentali, cardiovascolari e muscolari a sostanze neuroattive, permettendo il triage dei composti e la previsione dei meccanismi d'azione tramite apprendimento automatico. Questa tecnologia è utile sia per la scoperta commerciale di farmaci per il sistema nervoso centrale che per applicazioni difensive, con particolare attenzione alle contromisure contro sostanze armate come il Sarin.

Renovaro Inc. (NASDAQ:RENB) ha anunciado el lanzamiento de una plataforma de cribado basada en IA para peces cebra a través de su subsidiaria BioSymetrics, diseñada para identificar contramedidas médicas contra agentes químicos neurotóxicos. La plataforma, integrada en el Programa de Contramedidas de Defensa de Renovaro, representa la entrada estratégica de la compañía en biotecnología y biodefensa.

La plataforma de la empresa cuenta con avanzado preprocesamiento de datos y pruebas de toxicidad in vivo, capaz de analizar más de 1,000 compuestos por semana. Este avance está respaldado por una patente recién anunciada titulada "Métodos, Sistemas y Marcos para Datos Imparciales en Predicciones de Descubrimiento de Medicamentos", fortaleciendo la cartera de propiedad intelectual de Renovaro.

La plataforma captura respuestas conductuales, cardiovasculares y musculares a químicos neuroactivos, permitiendo la clasificación de compuestos y la predicción del mecanismo de acción mediante aprendizaje automático. Esta tecnología sirve tanto para el descubrimiento comercial de fármacos para el SNC como para aplicaciones defensivas, enfocándose especialmente en contramedidas contra sustancias armadas como el Sarín.

Renovaro Inc. (NASDAQ:RENB)는 자회사 BioSymetrics를 통해 AI 기반 제브라피쉬 스크리닝 플랫폼을 출시했다고 발표했습니다. 이 플랫폼은 신경독성 화학 물질에 대한 의료 대응책을 식별하기 위해 설계되었으며, Renovaro의 국방 대응 프로그램에 통합되어 바이오테크놀로지 및 생물방어 분야로의 전략적 진입을 의미합니다.

이 회사의 플랫폼은 고급 데이터 전처리 및 생체 내 독성 테스트 기능을 갖추고 있어 주당 1,000개 이상의 화합물을 선별할 수 있습니다. 이 개발은 "약물 발견 예측에서 편향 없는 데이터에 대한 방법, 시스템 및 프레임워크"라는 새로운 특허 출원으로 지원되어 Renovaro의 지적 재산권 포트폴리오를 강화합니다.

이 플랫폼은 신경 활성 화학 물질에 대한 행동, 심혈관 및 근육 반응을 포착하여 기계 학습을 통한 화합물 선별과 작용 기전 예측을 가능하게 합니다. 이 기술은 상업용 중추신경계 약물 발견과 국방 응용 모두에 활용되며, 특히 Sarin과 같은 무기화된 물질에 대한 대응책에 중점을 둡니다.

Renovaro Inc. (NASDAQ:RENB) a annoncé le lancement d'une plateforme de criblage basée sur l'IA utilisant le poisson zèbre, via sa filiale BioSymetrics, conçue pour identifier des contre-mesures médicales contre les agents chimiques neurotoxiques. Cette plateforme, intégrée au Programme de Contre-Mesures Défensives de Renovaro, marque l'entrée stratégique de l'entreprise dans la biotechnologie et la défense biologique.

La plateforme de la société propose un prétraitement avancé des données et des tests de toxicité in vivo, capable de cribler plus de 1 000 composés par semaine. Ce développement est soutenu par un brevet récemment annoncé intitulé « Méthodes, Systèmes et Cadres pour des Données Non Biaisées dans les Prédictions de Découverte de Médicaments », renforçant le portefeuille de propriété intellectuelle de Renovaro.

La plateforme capture les réponses comportementales, cardiovasculaires et musculaires aux produits chimiques neuroactifs, permettant une sélection des composés et une prédiction des mécanismes d'action basées sur l'apprentissage automatique. Cette technologie sert à la fois la découverte commerciale de médicaments pour le système nerveux central et les applications de défense, en se concentrant particulièrement sur les contre-mesures contre des substances militarisées comme le Sarin.

Renovaro Inc. (NASDAQ:RENB) hat die Einführung einer KI-basierten Zebrafisch-Screening-Plattform über seine Tochtergesellschaft BioSymetrics bekannt gegeben, die darauf ausgelegt ist, medizinische Gegenmaßnahmen gegen neurotoxische chemische Stoffe zu identifizieren. Die Plattform, die in Renovaros Verteidigungs-Gegenmaßnahmenprogramm integriert ist, stellt den strategischen Einstieg des Unternehmens in die Biotechnologie und Biodefense dar.

Die Plattform des Unternehmens verfügt über fortschrittliche Datenvorverarbeitung und In-vivo-Toxizitätstests und kann über 1.000 Verbindungen pro Woche screenen. Diese Entwicklung wird durch ein kürzlich angemeldetes Patent für „Methoden, Systeme und Rahmenwerke für unverzerrte Daten bei Arzneimittelentdeckungsprognosen“ unterstützt, was das geistige Eigentum von Renovaro stärkt.

Die Plattform erfasst Verhaltens-, Herz-Kreislauf- und Muskelreaktionen auf neuroaktive Chemikalien und ermöglicht eine durch maschinelles Lernen gesteuerte Auswahl von Verbindungen sowie die Vorhersage des Wirkmechanismus. Diese Technologie dient sowohl der kommerziellen Entdeckung von ZNS-Medikamenten als auch Verteidigungsanwendungen, mit besonderem Fokus auf Gegenmaßnahmen gegen bewaffnete Substanzen wie Sarin.

Positive
  • Launch of proprietary AI-based zebrafish screening platform for neurotoxin countermeasures
  • New patent strengthening intellectual property portfolio in AI-driven drug discovery
  • High-throughput capability to screen over 1,000 compounds weekly
  • Strategic entry into dual-use biotechnology and biodefense sectors
  • Platform adaptability for both pharmaceutical and national security applications
Negative
  • None.

Insights

Renovaro's expansion into biodefense with AI-zebrafish platform creates dual-market potential in pharma and defense, strengthened by new patent protection.

Renovaro has strategically expanded its AI capabilities from traditional life sciences into the national security domain with an AI-based zebrafish screening platform for neurotoxin countermeasures. This move represents a significant business pivot that could diversify the company's revenue streams across both pharmaceutical and defense sectors.

The platform's technical capabilities are impressive - processing over 1,000 compounds weekly through automated screening that captures multiple physiological responses to neurotoxins. This throughput substantially outpaces traditional models, potentially accelerating the identification of countermeasures against weaponized substances like Sarin.

The announcement coincides with a new patent for "Methods, Systems, and Frameworks for Unbiased Data in Drug Discovery Predictions," which strengthens Renovaro's intellectual property portfolio in machine learning for biomedical data integration. This IP protection is crucial for maintaining competitive advantage in the AI-driven drug discovery space.

The dual-market strategy is particularly noteworthy. By positioning their technology for both pharmaceutical applications and defense contracts, Renovaro creates multiple commercialization pathways. Defense contracts typically offer stable, long-term revenue potential with less regulatory hurdles than pharmaceutical development, potentially providing steady cash flow while the company pursues longer-term drug discovery opportunities.

For investors, this represents a strategic de-risking - creating multiple shots on goal across distinct markets with different funding mechanisms, regulatory pathways, and commercialization timelines. The defense biotech sector also typically commands premium valuations due to national security implications and government contract potential.

LOS ANGELES, CALIFORNIA / ACCESS Newswire / June 30, 2025 / Renovaro Inc.'s (NASDAQ:RENB) wholly owned subsidiary BioSymetrics has unveiled a proprietary AI-based zebrafish screening platform designed to rapidly identify medical countermeasures for neurotoxic chemical agents, including weaponized substances like Sarin. The platform has been integrated into Renovaro's Defense Countermeasures Program, marking a strategic entry into the dual-use biotechnology and biodefense sector. Renovaro's platform is anchored by advanced data preprocessing coupled with in vivo toxicity testing, creating a robust, end-to-end discovery pipeline bolstered by their recently announced patent, "Methods, Systems, and Frameworks for Unbiased Data in Drug Discovery Predictions". This IP milestone expands the company's foundational portfolio, further protecting its machine learning infrastructure for multi-modal biomedical data integration and predictive analytics-core to its scalable drug discovery and diagnostics business.

"This is a defining moment for Renovaro as we extend the value of our AI platform from traditional life sciences into national security," said David Weinstein, CEO of Renovaro. "With a growing patent estate and entry into the defense market, we are unlocking new revenue channels and expanding the commercial potential of our core technologies."

Value Drivers:

  • Strengthened IP Portfolio: New patent adds to Renovaro's protected methods for real-time, reproducible analytics across distributed computing environments.

  • Defense Market Entry: Renovaro's AI-zebrafish platform enables high-throughput, physiologically relevant screening for CNS-active neurotoxins.

  • Commercial Expansion: Platform is highly adaptable to pharma applications, rare diseases, and clinical trial acceleration.

  • Differentiated AI Platform: Combines proprietary model optimization, advanced feature selection, and biological automation.

  • New Revenue Opportunities: Supports partnerships, licensing, and government grants/contracts in both biomedical and national security domains.

The AI-based platform which uses an inexpensive zebrafish-based model for validation of neurotoxicity predictions, delivers rapid, automated screening of over 1,000 compounds per week, significantly outpacing traditional animal models. It captures behavioural, cardiovascular, and muscular responses to neuroactive chemicals, enabling ML-driven compound triage and mechanism of action prediction. This capability is vital for both commercial CNS drug discovery and defense applications involving neurotoxic exposure.

"Investors increasingly seek companies with platforms that are both scientifically robust and commercially scalable," said Weinstein. "Our ability to serve large markets in biopharma and national security - each with deep funding pools and urgent unmet needs - creates a unique, de-risked growth trajectory."

About Renovaro Inc.

Renovaro Inc. (NASDAQ: RENB) is building category-defining AI-driven platforms for precision medicine, diagnostics, and biodefense. Its proprietary technologies transform complex biomedical data into predictive insights, enabling faster discovery, greater accuracy, and strategic partnerships across the life sciences and government sectors.

Investor Relations Contact:

Your Name: Nathen Fuentes
Title CFO
investors@renovaro.com
Company Website: www.renovarogroup.com

SOURCE: Renovaro Biosciences



View the original press release on ACCESS Newswire

FAQ

What is Renovaro's new AI-based platform designed to do?

Renovaro's AI-based zebrafish screening platform is designed to rapidly identify medical countermeasures for neurotoxic chemical agents, including weaponized substances like Sarin.

How many compounds can Renovaro's (RENB) new screening platform process weekly?

The platform can perform automated screening of over 1,000 compounds per week, significantly faster than traditional animal models.

What is the significance of Renovaro's new patent for their business?

The patent protects Renovaro's methods for real-time, reproducible analytics across distributed computing environments, expanding their foundational portfolio in machine learning infrastructure for biomedical data integration.

How does Renovaro's zebrafish screening platform work?

The platform captures behavioral, cardiovascular, and muscular responses to neuroactive chemicals, using machine learning for compound triage and mechanism of action prediction.

What markets will Renovaro's (RENB) new platform serve?

The platform will serve both the biopharma market for CNS drug discovery and the national security sector for defense applications involving neurotoxic exposure.
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