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Sana Biotechnology Announces Invited Oral Presentation at the 85th Annual American Diabetes Association Scientific Sessions

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Sana Biotechnology (NASDAQ: SANA) will present updated six-month clinical results for UP421, their hypoimmune-modified primary islet cell therapy for type 1 diabetes, at the 85th Annual American Diabetes Association Scientific Sessions. The presentation, scheduled for June 23, 2025, in Chicago, will highlight data from a first-in-human study where UP421, an allogeneic primary islet cell therapy using Sana's hypoimmune (HIP) technology, was transplanted into a patient without requiring immunosuppression. The presentation will be part of a joint symposium between the American Diabetes Association (ADA) and International Pancreas & Islet Transplant Association (IPITA) focused on immune protection for cell replacement therapy.
Sana Biotechnology (NASDAQ: SANA) presenterà i risultati clinici aggiornati a sei mesi di UP421, la loro terapia con cellule insulari primarie modificate ipoimmuni per il diabete di tipo 1, durante la 85ª Sessione Scientifica Annuale dell'American Diabetes Association. La presentazione, prevista per il 23 giugno 2025 a Chicago, metterà in evidenza i dati di uno studio first-in-human in cui UP421, una terapia con cellule insulari primarie allogeniche che utilizza la tecnologia ipoimmune (HIP) di Sana, è stata trapiantata in un paziente senza necessità di immunosoppressione. L'intervento farà parte di un simposio congiunto tra l'American Diabetes Association (ADA) e l'International Pancreas & Islet Transplant Association (IPITA) incentrato sulla protezione immunitaria per la terapia di sostituzione cellulare.
Sana Biotechnology (NASDAQ: SANA) presentará resultados clínicos actualizados a seis meses de UP421, su terapia con células de islote primarias modificadas hipoinmunes para la diabetes tipo 1, en la 85ª Sesión Científica Anual de la American Diabetes Association. La presentación, programada para el 23 de junio de 2025 en Chicago, destacará datos de un estudio first-in-human donde UP421, una terapia con células de islote primarias alogénicas que utiliza la tecnología hipoinmune (HIP) de Sana, fue trasplantada en un paciente sin requerir inmunosupresión. La presentación formará parte de un simposio conjunto entre la American Diabetes Association (ADA) y la International Pancreas & Islet Transplant Association (IPITA) centrado en la protección inmune para la terapia de reemplazo celular.
Sana Biotechnology (NASDAQ: SANA)는 제85회 미국 당뇨병 학회 연례 과학 세션에서 제1형 당뇨병 치료를 위한 저면역성 변형 1차 이자세포 치료제 UP421의 6개월 임상 결과 업데이트를 발표할 예정입니다. 2025년 6월 23일 시카고에서 예정된 발표에서는 Sana의 저면역(HIP) 기술을 적용한 동종 1차 이자세포 치료제 UP421이 면역억제제 없이 환자에게 이식된 최초 인간 대상 연구 데이터를 중점적으로 다룰 예정입니다. 이 발표는 미국 당뇨병 학회(ADA)와 국제 이자 및 이자세포 이식 학회(IPITA)가 공동 주최하는 세포 대체 치료를 위한 면역 보호에 관한 심포지엄의 일부로 진행됩니다.
Sana Biotechnology (NASDAQ : SANA) présentera les résultats cliniques actualisés à six mois pour UP421, leur thérapie cellulaire primaire hypoimmune modifiée pour le diabète de type 1, lors des 85èmes Sessions Scientifiques Annuelles de l'American Diabetes Association. La présentation, prévue le 23 juin 2025 à Chicago, mettra en lumière les données d'une étude first-in-human où UP421, une thérapie cellulaire primaire allogénique utilisant la technologie hypoimmune (HIP) de Sana, a été transplantée chez un patient sans nécessiter d'immunosuppression. Cette présentation fera partie d'un symposium conjoint entre l'American Diabetes Association (ADA) et l'International Pancreas & Islet Transplant Association (IPITA) axé sur la protection immunitaire pour la thérapie de remplacement cellulaire.
Sana Biotechnology (NASDAQ: SANA) wird auf der 85. Jahrestagung der American Diabetes Association aktualisierte sechsmonatige klinische Ergebnisse für UP421 vorstellen, ihre hypoimmunmodifizierte primäre Inselzelltherapie für Typ-1-Diabetes. Die Präsentation, geplant für den 23. Juni 2025 in Chicago, wird Daten aus einer First-in-Human-Studie hervorheben, bei der UP421, eine allogene primäre Inselzelltherapie unter Verwendung der hypoimmunen (HIP) Technologie von Sana, einem Patienten ohne Immunsuppression transplantiert wurde. Die Präsentation ist Teil eines gemeinsamen Symposiums der American Diabetes Association (ADA) und der International Pancreas & Islet Transplant Association (IPITA), das sich auf den Immunschutz für Zellersatztherapien konzentriert.
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Presentation to highlight updated six-month clinical results of a hypoimmune-modified primary pancreatic islet cell therapy for patients with type 1 diabetes

SEATTLE, June 09, 2025 (GLOBE NEWSWIRE) -- Sana Biotechnology, Inc. (NASDAQ: SANA), a company focused on changing the possible for patients through engineered cells, today announced an upcoming podium presentation highlighting ongoing clinical data from the investigator-sponsored, first-in-human study transplanting UP421, an allogeneic primary islet cell therapy engineered with Sana’s hypoimmune (HIP) technology, into a patient with type 1 diabetes without the use of any immunosuppression. The presentation will be held during a joint American Diabetes Association (ADA)/International Pancreas & Islet Transplant Association (IPITA) symposium at the 85th Annual ADA Scientific Sessions taking place June 20-23, 2025 in Chicago, IL.

Presentation details:

Symposium Title: Joint ADA/IPITA Symposium: Outpacing the Immune System—Sprinting Towards Immune Protection for Cell Replacement Therapy
Presentation Title: Hypoimmune Pancreatic Islet Transplantation in Adult Subjects with Type 1 Diabetes
Presentation Date: Monday, June 23, 2025
Presentation Time: 9:00 – 9:20 a.m. CT
Location: W192 A-C
   

About Sana

Sana Biotechnology, Inc. is focused on creating and delivering engineered cells as medicines for patients. We share a vision of repairing and controlling genes, replacing missing or damaged cells, and making our therapies broadly available to patients. We are a passionate group of people working together to create an enduring company that changes how the world treats disease. Sana has operations in Seattle, WA, Cambridge, MA, South San Francisco, CA and Bothell, WA.

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements about Sana Biotechnology, Inc. (the “Company,” “we,” “us,” or “our”) within the meaning of the federal securities laws, including those related to the company’s vision and expectations regarding participation in and the presentation at the 85th Annual American Diabetes Association Scientific Sessions, including the content of such presentation. All statements other than statements of historical facts contained in this press release, including, among others, statements regarding the Company’s strategy, expectations, cash runway and future financial condition, future operations, and prospects, are forward-looking statements. In some cases, you can identify forward-looking statements by terminology such as “aim,” “anticipate,” “assume,” “believe,” “contemplate,” “continue,” “could,” “design,” “due,” “estimate,” “expect,” “goal,” “intend,” “may,” “objective,” “plan,” “positioned,” “potential,” “predict,” “seek,” “should,” “target,” “will,” “would,” and other similar expressions that are predictions of or indicate future events and future trends, or the negative of these terms or other comparable terminology. The Company has based these forward-looking statements largely on its current expectations, estimates, forecasts and projections about future events and financial trends that it believes may affect its financial condition, results of operations, business strategy and financial needs. In light of the significant uncertainties in these forward-looking statements, you should not rely upon forward-looking statements as predictions of future events. These statements are subject to risks and uncertainties that could cause the actual results to vary materially, including, among others, the risks inherent in drug development such as those associated with the initiation, cost, timing, progress and results of the Company’s current and future research and development programs, preclinical and clinical trials, as well as economic, market, and social disruptions. For a detailed discussion of the risk factors that could affect the Company’s actual results, please refer to the risk factors identified in the Company’s Securities and Exchange Commission reports, including but not limited to its Quarterly Report on Form 10-Q dated May 8, 2025. Except as required by law, the Company undertakes no obligation to update publicly any forward-looking statements for any reason.

Investor Relations & Media:
Nicole Keith
investor.relations@sana.com
media@sana.com


FAQ

What will Sana Biotechnology present at the 2025 ADA Scientific Sessions?

Sana Biotechnology will present updated six-month clinical results of UP421, their hypoimmune-modified primary islet cell therapy for type 1 diabetes patients, during a joint ADA/IPITA symposium on June 23, 2025.

What is unique about Sana Biotechnology's UP421 treatment for type 1 diabetes?

UP421 is an allogeneic primary islet cell therapy engineered with Sana's hypoimmune (HIP) technology that can be transplanted without requiring immunosuppression.

When and where will SANA present their diabetes treatment results?

The presentation will take place on Monday, June 23, 2025, from 9:00-9:20 a.m. CT at the 85th Annual ADA Scientific Sessions in Chicago, IL, in location W192 A-C.

What is the focus of the ADA/IPITA symposium where SANA will present?

The symposium is titled 'Outpacing the Immune System—Sprinting Towards Immune Protection for Cell Replacement Therapy' and focuses on immune protection strategies for cell replacement therapy.
Sana Biotechnology, Inc.

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