SOPHiA GENETICS Announces Two Million Patient Cases Analyzed, Marking a New Milestone for Data-Driven Medicine at NVIDIA GTC

Rhea-AI Summary

SOPHiA GENETICS (Nasdaq: SOPH) has achieved a significant milestone by analyzing over two million patient genomic profiles through its AI-powered SOPHiA DDM™ Platform. This achievement, announced at NVIDIA GTC, represents a doubling of analyzed profiles since 2022.

The platform currently serves 800 healthcare institutions across 72 countries, processing thousands of oncology and rare disease cases daily. SOPHiA DDM™'s AI capabilities are uniquely shaped by real-world data, enabling faster and more accurate treatment decisions.

Healthcare professionals worldwide have reported significant benefits from the platform:

• CHU Lyon, France reports faster and more efficient analysis of hereditary cardiac pathologies
• Karkinos Healthcare in India has expanded advanced cancer diagnostics to underserved communities
• Fondazione Policlinico Universitario Gemelli in Italy utilizes the platform for various genetic analyses
• UCSF Clinical Cancer Genomics Lab successfully identifies complex genetic rearrangements in cancer cases

Positive

• Doubled analyzed genomic profiles from 1M to 2M in less than 3 years, showing rapid growth
• Large-scale adoption across 800 healthcare institutions in 72 countries
• Platform processes thousands of cases daily, indicating strong utilization
• Real-world data implementation enhances AI capabilities and accuracy

Negative

• None.

Insights

AI Healthcare & Genomics Analyst

SOPHiA GENETICS has reached a significant operational milestone with two million patient genomic profiles analyzed on its SOPHiA DDM™ Platform, doubling its previous milestone announced in 2022. This acceleration in adoption across 800 healthcare institutions in 72 countries demonstrates growing market penetration and platform trust in the competitive AI healthcare analytics space.

The scale of data now feeding SOPHiA's AI models represents a meaningful competitive advantage. In AI-driven healthcare, dataset size and diversity directly correlate with model accuracy and clinical utility. With thousands of new oncology and rare disease cases analyzed daily, SOPHiA's algorithms benefit from continuous real-world training—creating a virtuous cycle where more usage leads to better performance, potentially driving further adoption.

While the announcement lacks financial metrics, SOPHiA's platform expansion suggests positive underlying business momentum. The company's global footprint across diverse healthcare systems indicates strong product-market fit and minimal geographic concentration risk. Customer testimonials from major institutions in France, India, Italy, and the United States highlight broad application across both developed and emerging healthcare markets.

For investors, this milestone represents validation of SOPHiA's platform strategy and execution capability in the growing precision medicine market. However, the company still faces the challenge of translating growing usage into corresponding revenue growth and eventual profitability—metrics not addressed in this announcement.

BOSTON, MA and ROLLE, Switzerland, March 18, 2025 /PRNewswire/ -- SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and leader in data-driven medicine, has reached a historic milestone: more than two million patients genomic profiles analyzed on the AI-powered analytics Platform SOPHiA DDM™. This achievement solidifies SOPHiA GENETICS as the gold-standard provider of actionable insights for patient care, applying AI capabilities shaped by an unmatched dataset of diverse, real-world patient data.

"When we announced one million profiles analyzed in 2022, it was a landmark moment in the evolution of data-driven medicine," said Jurgi Camblong, PhD., Chief Executive Officer and Co-founder of SOPHiA GENETICS. "Less than three years later, we have doubled that number, an acceleration that reflects both the trust our partners place in our Platform and the increasing role of AI in transforming healthcare."

With 800 healthcare institutions across 72 countries regularly contributing their data and expertise to SOPHiA DDM™, the Platform has become one of the most comprehensive sources of real-world intelligence in precision medicine. SOPHiA DDM^™ analyzes thousands of new oncology and rare disease cases daily, continuously refining and improving its AI capabilities. Unlike AI models trained in controlled environments, SOPHiA GENETICS's technology is uniquely shaped by real-world data, ensuring its insights are deeply rooted in clinical reality. Now informed by over two million patient cases, the Platform empowers providers to see what others cannot, leading to faster and more accurate treatment decisions.

"At SOPHiA GENETICS, our vision was to create a Platform that could harness genetic data to benefit patients worldwide. Reaching two million genomic profiles is a historic milestone, strengthening a Platform that now integrates hundreds of millions of data points across multiple health dimensions, driving even greater impact for precision medicine," commented Pierre Hutter, PhD., Co-founder and former CSO of SOPHiA GENETICS.

"When we founded SOPHiA GENETICS, our vision was to leverage data to make precision medicine accessible worldwide," added Lars Steinmetz, PhD., current Chair of the Department of Genetics at Stanford University and Co-founder of SOPHiA GENETICS. "From the beginning, we knew that scale and diversity of data would be essential to making AI truly impactful in healthcare. Today, the Platform reflects an unprecedented range of profiles, ensuring that AI-driven insights are not just powerful, but also inclusive and globally relevant."

Hospitals and research institutions worldwide use the SOPHiA DDM™ Platform to generate insights on genomic data and provide world-class patient care:

"We have been using the SOPHiA DDM™ Platform for nearly 10 years. Thanks to SOPHiA DDM™, the analysis of patients with hereditary cardiac pathologies at the second-largest university hospital in France is now faster and more efficient than ever. The Platform's ease of use significantly enhances our ability to provide timely and accurate results. Thank you for empowering our institution to make an impact on countless lives among the two million genomic analyses," said Gilles Millat, University Lecturer, Hospital Practitioner, CHU Lyon, France.

"Huge congratulations to SOPHiA GENETICS for reaching the incredible milestone of two million genomic analyses! Working together, we've brought advanced cancer diagnostics to more patients across India, including those in underserved communities. With the SOPHiA DDM™ Platform, we've strengthened our ability to generate evidence and world-class research for faster and more accurate diagnosis, and we hope to expand it further in the coming years. The real impact data-driven medicine has on patients' lives makes us proud to be part of this journey to transform cancer care in India and beyond," added Dr. R.Venkataramanan, Founder, Karkinos Healthcare, India.

The technology enables more effective and accurate treatment selection for cancer patients, at-scale:

"SOPHiA DDM™ allows us to tackle a wide range of genetic analyses at Fondazione Policlinico Universitario Agostino Gemelli, from exome sequencing to hereditary cancer and HRD testing, without compromising accuracy or efficiency," explains Dr. Angelo Minucci, Head of Molecular and Genomic Diagnostics Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, Italy.

"With SOPHiA DDM™, we have been able to confidently identify genetic rearrangements that provide critical insights into the complexity of cancer," said Dr. Jessica Van Ziffle, Associate Professor, Department of Pathology & Associate Director, UCSF Clinical Cancer Genomics Lab, United States. She added, "One recent analysis allowed us to leverage SOPHiA GENETICS's advanced algorithm to detect a BRCA1 rearrangement—an ALU insertion—that could have otherwise easily been missed. The ability to detect these challenging variants with precision ensures we acquire the best possible knowledge for research, patients, and their families."

SOPHiA GENETICS will celebrate this milestone across its global offices and alongside its partners, acknowledging the contributions of a network of healthcare professionals and patients worldwide. The announcement coincides with the NVIDIA GTC AI Conference in California, where the company will showcase its latest breakthroughs in data-driven medicine.

For more information on SOPHiA GENETICS, visit SOPHiAGENETICS.COM, or connect on LinkedIn. 

About SOPHiA GENETICS  
SOPHiA GENETICS (Nasdaq: SOPH) is a cloud-native healthcare technology company on a mission to expand access to data-driven medicine by using AI to deliver world-class care to patients with cancer and rare disorders across the globe. It is the creator of the SOPHiA DDM™ Platform, which analyzes complex genomic and multimodal data and generates real-time, actionable insights for a broad global network of hospital, laboratory, and biopharma institutions.  For more information, visit SOPHiAGENETICS.COM and connect with us on LinkedIn. 

SOPHiA GENETICS products are for Research Use Only and not for use in diagnostic procedures unless specified otherwise. The information in this press release is about products that may or may not be available in different countries and, if applicable, may or may not have received approval or market clearance by a governmental regulatory body for different indications for use. Please contact support@sophiagenetics.com to obtain the appropriate product information for your country of residence. 

SOPHiA GENETICS Forward-Looking Statements: 
This press release contains statements that constitute forward-looking statements. All statements other than statements of historical facts contained in this press release, including statements regarding our future results of operations and financial position, business strategy, products, and technology, as well as plans and objectives of management for future operations, are forward-looking statements. Forward-looking statements are based on our management's beliefs and assumptions and on information currently available to our management. Such statements are subject to risks and uncertainties, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various factors, including those described in our filings with the U.S. Securities and Exchange Commission. No assurance can be given that such future results will be achieved. Such forward-looking statements contained in this press release speak only as of the date hereof. We expressly disclaim any obligation or undertaking to update these forward-looking statements contained in this press release to reflect any change in our expectations or any change in events, conditions, or circumstances on which such statements are based, unless required to do so by applicable law. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements. 

Media Contact:
wpp_sophiagenetics@gcihealth.com

View original content to download multimedia:https://www.prnewswire.com/news-releases/sophia-genetics-announces-two-million-patient-cases-analyzed-marking-a-new-milestone-for-data-driven-medicine-at-nvidia-gtc-302404491.html

SOURCE SOPHiA GENETICS

FAQ

How many patient genomic profiles has SOPHiA GENETICS (SOPH) analyzed as of March 2025?

SOPHiA GENETICS has analyzed over two million patient genomic profiles through its SOPHiA DDM™ Platform as of March 2025.

What is the global reach of SOPHiA GENETICS' DDM Platform in 2025?

The SOPHiA DDM™ Platform serves 800 healthcare institutions across 72 countries.

How long did it take SOPHiA GENETICS (SOPH) to double its analyzed profiles from 1 to 2 million?

It took less than three years, from 2022 to 2025, to double the number of analyzed profiles from one to two million.

What types of medical cases does SOPHiA GENETICS' platform analyze daily?

The platform analyzes thousands of oncology and rare disease cases daily.