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Exicure to Settle GPCR Therapeutics Clinical Milestone Payment Through Equity Issuance

Exicure (Nasdaq:XCUR) plans to issue 172,058 shares of common stock to GPCR Therapeutics during August 2026 to settle a $1.0 million clinical milestone obligation under their License and Collaboration Agreement.

(Positive)
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Exicure (Nasdaq:XCUR) plans to issue 172,058 shares of common stock to GPCR Therapeutics during August 2026 to settle a $1.0 million clinical milestone obligation under their License and Collaboration Agreement. The payment obligation arose from completion of the Phase 2 clinical trial of Burixafor (GPC-100) and formal submission of the Clinical Study Report to the U.S. Food and Drug Administration on January 16, 2026.

The shares are expected to be issued at a deemed value of $5.81 per share, based on applicable Nasdaq trading data, for an aggregate deemed value of approximately $1.0 million. Exicure submitted a Listing of Additional Shares Notification to Nasdaq on July 31, 2026 and delivered issuance instructions to its transfer agent. The issuance is expected to be completed in August 2026, subject to customary Nasdaq and transfer agent review. Exicure’s CEO said the equity settlement is intended to preserve cash and maintain financial flexibility.

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Positive

  • $1.0 million milestone settled via equity, preserving cash resources
  • Planned issuance of 172,058 shares fixes equity consideration and valuation
  • Phase 2 trial of Burixafor (GPC-100) completed with CSR submitted on Jan 16, 2026

Negative

  • Issuance of 172,058 new shares adds to share count and dilutes existing holders
  • Equity-settled $1.0 million milestone reflects additional non-operating cost obligation
Argus Aug 3 session 3 alerts
-1.25% close to close 0.0x rel. volume Open Argus
Details

News Market Reaction – XCUR

$9.75M Market Cap

In the Aug 3 session, XCUR declined 1.25%, reflecting a mild negative market reaction. Our momentum scanner triggered 3 alerts that day, indicating moderate trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

Exicure's recent record included 0.05% after co-development news and -6.61% after a delayed filing, ...
Analysis

Exicure's recent record included 0.05% after co-development news and -6.61% after a delayed filing, showing mixed precedents. The stock-issuance settlement should be weighed against moderate short positioning; watch completion and Nasdaq processing.

Key Figures

Shares to be issued: 172,058 shares Milestone payment: $1.0 million Trial phase: Phase 2 +3 more
Shares to be issued
172,058 shares
Settlement of clinical milestone payment
Milestone payment
$1.0 million
Obligation under the License and Collaboration Agreement
Trial phase
Phase 2
Burixafor clinical trial
Clinical Study Report submission
January 16, 2026
Formal submission to the U.S. Food and Drug Administration
Deemed issue value
$5.81 per share
Based on applicable Nasdaq trading data
Aggregate deemed value
$1.0 million
Equity issuance settlement

Historical Context

5 past events · Latest: Jun 30
5 events
  1. Jun 30

    Board changes

    24h Move
    -5.5%

    Board expanded and committee memberships changed following a director resignation.

  2. Jun 10

    Nasdaq notice

    24h Move
    +2.2%

    Nasdaq cited noncompliance with the minimum stockholders’ equity requirement.

  3. Jun 01

    Delinquency notice

    24h Move
    -6.6%

    Nasdaq issued a delinquency notice after the delayed quarterly filing.

  4. Apr 22

    Co-development agreement

    24h Move
    +0.1%

    Adbiotech agreed to explore combination therapies using Burixafor.

  5. Mar 25

    Full-year results

    24h Move
    +0.0%

    Cash declined and management cited insufficient liquidity for the next twelve months.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

clinical study report, phase 2 clinical trial, transfer agent
3 terms
clinical study report regulatory
"including the formal submission of the Clinical Study Report to the U.S. Food and Drug Administration"
A clinical study report is a detailed, written account of a medical trial that explains how the study was run, what happened to participants, and the full results on safety and effectiveness. Think of it as the study’s final report card and instruction manual combined: regulators and investors use it to judge whether a drug or device works, what risks it carries, and whether it can move toward approval or commercialization — factors that directly affect a company’s value and prospects.
phase 2 clinical trial medical
"The milestone payment was triggered by the completion of the Phase 2 clinical trial"
A phase 2 clinical trial is a research study that tests a new medical treatment or drug to see if it is effective and safe for a specific condition. It involves a larger group of people than earlier trials and helps determine whether the treatment should move forward to more extensive testing. For investors, successful phase 2 results can signal potential for future approval and commercial success, while setbacks may indicate challenges ahead.
transfer agent financial
"delivered the applicable treasury issuance instructions to its transfer agent"
A transfer agent is a financial service that keeps the official record of who owns a company's shares, handles the buying and selling of those shares on paper or electronically, and issues or cancels stock certificates. Think of it as the company’s records keeper and mailroom combined—investors rely on it to make sure dividends, shareholder mailings, ownership changes, and proxy voting are processed accurately and securely, which protects ownership rights and helps prevent errors or fraud.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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WILMINGTON, Del., Aug. 03, 2026 (GLOBE NEWSWIRE) -- Exicure, Inc. (Nasdaq: XCUR) (“Exicure” or the “Company”) today announced that it expects to issue 172,058 shares of its common stock to GPCR Therapeutics, Inc. (“GPCR Therapeutics”) during August 2026 in settlement of a $1.0 million clinical milestone payment obligation under the parties’ License and Collaboration Agreement.

The milestone payment was triggered by the completion of the Phase 2 clinical trial of Burixafor (GPC-100), including the formal submission of the Clinical Study Report to the U.S. Food and Drug Administration on January 16, 2026.

The shares are expected to be issued at a deemed value of $5.81 per share, based on applicable Nasdaq trading data, representing an aggregate deemed value of approximately $1.0 million.

On July 31, 2026, the Company submitted a Listing of Additional Shares Notification to The Nasdaq Stock Market in connection with the equity issuance. The Company also completed and delivered the applicable treasury issuance instructions to its transfer agent, Equiniti Trust Company, LLC.

The Company expects the issuance to be completed during August 2026, subject to the completion of customary Nasdaq and transfer agent review and processing procedures. Exicure intends to provide an additional update following completion of the issuance.

“Settling this milestone payment through the issuance of common stock will allow Exicure to preserve cash and maintain financial flexibility as we continue to pursue our operational and strategic priorities,” said Jung Soo Kim, Chief Executive Officer of Exicure.

About Exicure, Inc.

Exicure, Inc. (Nasdaq: XCUR) has historically been an early-stage biotechnology company focused on developing nucleic acid therapies targeting ribonucleic acid against validated targets. Following its restructuring and suspension of clinical and development activities, the Company is exploring strategic alternatives to maximize stockholder value. In January 2025, it acquired a clinical-stage biotechnology company developing therapeutics for hematologic diseases. The Company’s lead program is being evaluated for its ability to improve stem cell mobilization in multiple myeloma, sickle cell disease, and in support of cell and gene therapy.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of applicable federal securities laws, including statements regarding the anticipated issuance of shares to GPCR Therapeutics, the expected timing and completion of the issuance, the settlement of the Company’s milestone payment obligation, and the Company’s strategic direction. Forward-looking statements are based on management’s current expectations and assumptions and are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. The Company undertakes no obligation to update any forward-looking statements except as required by applicable law.

Media Contact

Exicure, Inc.
pr@exicuretx.com


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What did Exicure (NASDAQ:XCUR) announce on August 3, 2026 regarding GPCR Therapeutics?

Exicure announced plans to issue 172,058 shares of common stock to GPCR Therapeutics to settle a $1.0 million clinical milestone. According to Exicure, this stems from a milestone under their License and Collaboration Agreement tied to Burixafor (GPC-100).

How many Exicure (XCUR) shares will be issued to GPCR Therapeutics and at what value?

Exicure expects to issue 172,058 shares of common stock to GPCR Therapeutics at a deemed value of $5.81 per share. According to Exicure, this represents an aggregate deemed value of approximately $1.0 million based on applicable Nasdaq trading data.

What triggered the $1.0 million clinical milestone payment in Exicure’s agreement with GPCR Therapeutics?

The milestone was triggered by completion of the Phase 2 trial of Burixafor (GPC-100) and submission of the Clinical Study Report to the FDA on January 16, 2026. According to Exicure, this event activated the $1.0 million payment obligation.

When is Exicure (XCUR) expected to complete the equity issuance to GPCR Therapeutics?

Exicure expects to complete the share issuance during August 2026, subject to customary Nasdaq and transfer agent review and processing. According to Exicure, a Listing of Additional Shares Notification was submitted to Nasdaq on July 31, 2026.

Why is Exicure settling the GPCR Therapeutics milestone payment in stock instead of cash?

Exicure is settling the $1.0 million milestone through common stock issuance to preserve cash and maintain financial flexibility. According to Exicure, this approach supports its ongoing operational and strategic priorities while meeting its obligation to GPCR Therapeutics.

What is the role of the Burixafor (GPC-100) Phase 2 trial in Exicure’s share issuance?

Completion of the Phase 2 Burixafor (GPC-100) trial and FDA Clinical Study Report submission on January 16, 2026 triggered the milestone payment. According to Exicure, this clinical milestone is being satisfied via issuance of 172,058 XCUR shares to GPCR Therapeutics.

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