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Exagen Inc. Reports First Quarter 2026 Results

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Exagen (Nasdaq:XGN) reported record Q1 2026 revenue of $17.3 million, up 12% year over year, with gross margin of 59.0% and AVISE CTD test volume up 10%.

Trailing-twelve-month AVISE CTD ASP rose 6% to $444. Net loss was $4.0 million and adjusted EBITDA loss improved to $2.2 million. Cash and equivalents were about $22 million. Full-year 2026 revenue guidance remains $70–$73 million.

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AI-generated analysis. Not financial advice.

Positive

  • Record Q1 2026 revenue of $17.3 million, up 12% year over year
  • AVISE CTD test volume grew 10% versus Q1 2025
  • Trailing-twelve-month AVISE CTD ASP increased 6% to $444
  • Adjusted EBITDA loss improved to $2.2 million from $2.5 million
  • Cash and equivalents increased to about $22 million from $11.2 million
  • Full-year 2026 revenue guidance maintained at $70–$73 million

Negative

  • Q1 2026 operating loss widened slightly to $3.4 million
  • Q1 2026 net loss increased to $4.0 million
  • Operating expenses rose to $13.6 million from $12.5 million

Market Reaction – XGN

+4.41% $3.08 4.9x vol
15m delay 20 alerts
+4.41% Since News
+14.7% Peak in 7 min
$3.08 Last Price
$2.82 $3.10 Day Range
+$3M Valuation Impact
$71.22M Market Cap
4.9x Rel. Volume

Following this news, XGN has gained 4.41%, reflecting a moderate positive market reaction. Argus tracked a peak move of +14.7% during the session. Our momentum scanner has triggered 20 alerts so far, indicating elevated trading interest and price volatility. The stock is currently trading at $3.08. This price movement has added approximately $3M to the company's valuation. Trading volume is very high at 4.9x the average, suggesting strong buying interest.

Data tracked by StockTitan Argus (15 min delayed). Upgrade to Gold for real-time data.

Key Figures

Q1 2026 revenue: $17.3M Gross margin: 59.0% Operating loss: $3,414K +5 more
8 metrics
Q1 2026 revenue $17.3M Three months ended March 31, 2026; record total revenue, up 12% YoY
Gross margin 59.0% Q1 2026 gross margin vs 58.9% in Q1 2025
Operating loss $3,414K Q1 2026 operating loss (vs $3,365K in Q1 2025)
Net loss $3,967K Q1 2026 net loss (vs $3,752K in Q1 2025)
Adjusted EBITDA loss $2,160K Q1 2026 adjusted EBITDA loss, 14% improvement vs Q1 2025
AVISE CTD ASP $444 Trailing-twelve-month ASP, up $25 per test (+6%) vs Q1 2025
AVISE CTD volume growth 10% Q1 2026 test volume increase vs first quarter 2025
Cash & cash equivalents $21,513K Cash and cash equivalents at March 31, 2026

Market Reality Check

Price: $2.95 Vol: Volume 211,077 is roughly...
normal vol
$2.95 Last Close
Volume Volume 211,077 is roughly in line with the 20-day average of 215,471 (relative volume 0.98). normal
Technical Shares traded below the 200-day MA of 6.77, reflecting a longer-term downtrend ahead of these results.

Peers on Argus

XGN was up 0.34% pre-news context while momentum peers were mixed: PRE up 3.16% ...
1 Up 1 Down

XGN was up 0.34% pre-news context while momentum peers were mixed: PRE up 3.16% and PSNL down 3.18%. Broader diagnostics peers in the affinity list also showed both gains and losses, pointing to company-specific rather than sector-driven moves.

Previous Earnings Reports

5 past events · Latest: Jan 11 (Positive)
Same Type Pattern 5 events
Date Event Sentiment Move Catalyst
Jan 11 Prelim 2025 results Positive -6.2% Preliminary 2025 revenue, volume, ASP and cash all up versus 2024.
Nov 04 Q3 2025 earnings Positive -9.0% Strong Q3 2025 revenue growth, higher ASP and reduced EBITDA loss.
Jul 29 Q2 2025 earnings Positive +14.3% Record Q2 2025 revenue, higher CTD volume and improved gross margin.
May 05 Q1 2025 earnings Positive +3.8% Record Q1 2025 revenue, rising ASP and new credit facility support.
Mar 11 FY 2024 earnings Positive +18.3% Record 2024 revenue with higher gross margin and reduced net loss.
Pattern Detected

Earnings releases have often been positive on fundamentals, with three past reports seeing aligned price gains and two showing selloffs despite strong growth metrics.

Recent Company History

Over the past year, Exagen has repeatedly reported record or strong results, with revenue climbing from $55.6M in full-year 2024 to $66.6M in 2025 and a trailing ASP rising into the $441 range. Prior earnings in Q1–Q3 2025 highlighted growing AVISE CTD volume, margin expansion, and improving adjusted EBITDA. The current Q1 2026 update, with record quarterly revenue and higher ASP, extends this trajectory and ties back to earlier guidance for 2026 revenue of $70M–$73M.

Historical Comparison

+4.3% avg move · Across five prior earnings-related releases, XGN moved an average of 4.26%. Today’s pre-context move...
earnings
+4.3%
Average Historical Move earnings

Across five prior earnings-related releases, XGN moved an average of 4.26%. Today’s pre-context move of 0.34% was modest versus typical earnings volatility.

Earnings updates show a progression of rising revenue and AVISE CTD ASP from 2024 through 2025, with guidance pointing to further topline growth into 2026.

Regulatory & Risk Context

Active S-3 Shelf · $8.5 million
Shelf Active
Active S-3 Shelf Registration 2025-06-20
$8.5 million registered capacity

An effective Form S-3 shelf dated 2025-06-20 registers up to 1,150,000 warrant shares for resale, tied to a $75 million Perceptive term loan. The company receives no proceeds from resales, only potential cash on warrant exercise, so investors face both potential dilution and high-cost leverage through 2030.

Market Pulse Summary

This announcement reports record Q1 2026 revenue of $17.3M, improved AVISE CTD metrics, and continue...
Analysis

This announcement reports record Q1 2026 revenue of $17.3M, improved AVISE CTD metrics, and continued guidance for $70M–$73M in 2026 revenue, while losses and adjusted EBITDA remain negative. Historically, earnings releases have produced mixed stock reactions despite growth. Investors may watch how revenue growth, ASP expansion, and cash of $21.5M balance against ongoing losses and the overhang from 1,150,000 registered warrant shares tied to a $75M term loan.

Key Terms

adjusted EBITDA, non-GAAP financial measure, warrant liability
3 terms
adjusted EBITDA financial
"Delivered an adjusted EBITDA loss of $2.2 million, an improvement of 14%..."
Adjusted EBITDA is a way companies measure how much money they make from their core operations, like running a business, by removing certain costs or income that aren’t part of regular business activities. It helps investors see how well a company is doing without distractions from unusual expenses or gains, making it easier to compare companies or track performance over time.
non-GAAP financial measure financial
"adjusted EBITDA, which is not calculated in accordance with GAAP and is a non-GAAP financial measure."
A non-GAAP financial measure is a way companies present their financial results that excludes certain expenses or income to show how they believe their core business is performing. It matters because it can give a clearer picture of how the company is really doing, but it can also be used to make results look better than they actually are.
warrant liability financial
"change in fair value of warrant liability, and certain other non‑cash..."
Warrant liability is the financial obligation a company records when it grants warrants—special options giving the holder the right to buy company shares at a set price in the future. It matters to investors because changes in this liability can affect a company's reported earnings and overall financial health, similar to how a pending contract can influence a company's future value.

AI-generated analysis. Not financial advice.

Delivers record total revenue and AVISE(R) CTD average selling price

CARLSBAD, Calif., May 11, 2026 (GLOBE NEWSWIRE) -- Exagen Inc. (Nasdaq: XGN), a leading provider of autoimmune testing solutions, today reported financial results for the quarter ended March 31, 2026, and recent corporate updates.

  Three Months Ended March 31,
   2026
  2025
Unaudited. In thousands, except ASP data.  
Revenue $17,306  $15,498 
Gross margin  59.0%  58.9%
Operating expenses $13,619  $12,488 
Operating loss $(3,414) $(3,365)
Net loss $(3,967) $(3,752)
Adjusted EBITDA $(2,160) $(2,508)
Trailing-twelve-month average selling price (ASP) $444  $419 
Cash and cash equivalents $21,513  $11,194 
         

First Quarter 2026 Highlights:

  • Achieved record total revenue of $17.3 million, an increase of 12% compared to first quarter 2025.
  • Grew AVISE CTD test volume 10% compared to first quarter 2025.
  • Expanded AVISE CTD trailing-twelve-month ASP to $444 per test, an increase of $25 per test, or 6% compared to first quarter 2025.
  • Delivered an adjusted EBITDA loss of $2.2 million, an improvement of 14% compared to first quarter 2025.
  • Ended the quarter with approximately $22 million in cash and cash equivalents, ahead of expectations and consistent with long-standing strategy to hold claims in the first quarter.

“First quarter results establish a solid start to 2026, reflecting our team’s disciplined execution and effective revenue cycle management,” said John Aballi, President and CEO. “Exagen is uniquely committed to providing clarity for autoimmune patients and confidence for clinicians. We have built a foundation to expand our reach and advance innovation in a market with significant unmet need.”

2026 Guidance 

The Company continues to expect full-year 2026 revenue of $70 million to $73 million.

Conference Call

A conference call to review first quarter financial results is scheduled for today, May 11, 2026, at 8:30 a.m. ET (5:30 a.m. PT). Interested parties may access the conference call by dialing (877) 407-0890 (U.S.), or +1 (201) 389-0918 (international). Additionally, a link to a live webcast of the call will be available in the Investor Relations section of Exagen's website at investors.exagen.com. Participants are asked to join a few minutes prior to the call to register for the event.

A replay of the conference call will be available until May 25, 2026. Interested parties may access the replay by dialing (877) 660-6853 (U.S.) or +1 (201) 612-7415 (international) using passcode 13759736. A link to the replay of the webcast will also be available in the Investor Relations section of Exagen's website.

Use of Non-GAAP Financial Measures (UNAUDITED)

In addition to the financial results prepared in accordance with generally accepted accounting principles in the United States (GAAP), this press release contains the metric adjusted EBITDA, which is not calculated in accordance with GAAP and is a non-GAAP financial measure. Adjusted EBITDA is defined as net loss adjusted for interest income (expense), income tax expense (benefit), depreciation and amortization expense, stock‑based compensation expense, change in fair value of warrant liability, and certain other non‑cash, unusual or non‑recurring items, including, for example, losses on extinguishment of debt and changes in the fair value of warrant liabilities; we do not exclude normal, recurring, cash operating expenses from this measure. Such items could have a significant impact on the calculation of GAAP net loss.

Exagen uses adjusted EBITDA internally because the company believes these metrics provide useful supplemental information in assessing its operating performance reported in accordance with GAAP. Exagen believes adjusted EBITDA may enhance an evaluation of the operating performance because it excludes the impact of prior decisions made about capital investment, financing, investing and certain expenses the company believes are not indicative of the ongoing performance. However, this non-GAAP financial measure may be different from non-GAAP financial measures used by other companies, even when the same or similarly titled terms are used to identify such measures, limiting their usefulness for comparative purposes.

This non-GAAP financial measure is not meant to be considered in isolation or used as a substitute for net loss reported in accordance with GAAP, should be considered in conjunction with the financial information presented in accordance with GAAP, has no standardized meaning prescribed by GAAP, is unaudited, and is not prepared under any comprehensive set of accounting rules or principles. In addition, from time to time in the future, there may be other items that Exagen may exclude for purposes of these non-GAAP financial measures, and the company may in the future cease to exclude items that it has historically excluded for purposes of these non-GAAP financial measures. Likewise, Exagen may determine to modify the nature of adjustments to arrive at these non-GAAP financial measures. Because of the non-standardized definitions of non-GAAP financial measures, the non-GAAP financial measure as used by the company in this press release and the accompanying reconciliation table have limits in their usefulness to investors and may be calculated differently from, and therefore may not be directly comparable to, similarly titled measures used by other companies. Accordingly, investors should not place undue reliance on non-GAAP financial measures.

A reconciliation of net loss to non-GAAP adjusted EBITDA is provided in the financial schedules that are part of this press release.

About Exagen

Exagen Inc. (Nasdaq: XGN) is a leading provider of autoimmune diagnostics, committed to transforming care for patients with chronic and debilitating autoimmune conditions. Based in San Diego County, California, Exagen’s mission is to provide clarity in autoimmune disease decision-making and improve clinical outcomes through its innovative testing portfolio. The company’s flagship product, AVISE® CTD, enables clinicians to more effectively diagnose complex autoimmune conditions such as lupus, rheumatoid arthritis, and Sjögren’s disease earlier and with greater accuracy. Exagen’s CLIA-certified, CAP-accredited laboratory specializes in the testing of rheumatic diseases, delivering precise and timely results, supported by a suite of AVISE-branded tests for disease diagnosis, prognosis, and monitoring. With a focus on research, innovation, education, and patient-centered care, Exagen is dedicated to addressing the ongoing challenges of autoimmune disease management.

For more information, visit Exagen.com or follow Exagen on LinkedIn.

Forward Looking Statements

Exagen cautions you that statements contained in this press release regarding matters that are not historical facts are forward-looking statements. These statements are based on Exagen’s current beliefs and expectations. Such forward-looking statements include, but are not limited to, statements regarding: Exagen’s goals, strategies, positioning, and ambitions; evaluations and judgments regarding financial results and the potential implications of those results, potential future financial and business performance, including any improvements to adjusted EBITDA, ASP, net loss and potential profitability; the potential utility and effectiveness of Exagen’s services and testing solutions; the anticipated benefits of and adoption trajectory for Exagen's recently launched biomarkers; the impact of Exagen's revenue cycle management strategy on the timing of collections and cash burn; potential stockholder value and growth and full-year 2026 guidance. The inclusion of forward-looking statements should not be regarded as a representation by Exagen that any of its plans will be achieved. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in Exagen’s business, including, without limitation: delays in reimbursement and coverage decisions from Medicare and third-party payors and interactions with regulatory authorities, and delays in ongoing and planned clinical trials involving its tests; the potential effects of inflation and tariffs on Exagen’s margins; and changes in laws and regulations related to Exagen’s regulatory requirements. Exagen’s commercial success depends upon attaining and maintaining significant market acceptance of its testing products among rheumatologists, patients, third-party payors and others in the medical community; Exagen’s ability to successfully execute on its business strategies; and ability to obtain additional funding; third-party payors not providing coverage and adequate reimbursement for Exagen’s testing products, including Exagen’s ability to collect on funds due; Exagen’s ability to obtain and maintain intellectual property protection for its testing products; regulatory developments affecting Exagen’s business; and other risks described in Exagen’s prior press releases and Exagen’s filings with the Securities and Exchange Commission (SEC), including under the heading “Risk Factors” in Exagen’s Annual Report on Form 10-K for the year ended December 31, 2025, filed with the SEC on March 10, 2026, and any subsequent filings with the SEC. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and Exagen undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.

Investors:
Tina Jacobsen, CFA
Exagen Inc.
ir@exagen.com

Exagen Inc.
 
Unaudited Condensed Statements of Operations
(in thousands, except share and per share amounts)
 
  Three Months Ended March 31,
   2026  2025
   
Revenue $17,306  $15,498 
Cost of revenue  7,101   6,375 
Gross margin  10,205   9,123 
Operating expenses:    
Selling, general and administrative expenses  12,066   11,204 
Research and development expenses  1,553   1,284 
Total operating expenses  13,619   12,488 
Loss from operations  (3,414)  (3,365)
Interest expense  (1,267)  (545)
Change in fair value of warrant liability  882    
Other income (expense), net  (132)  158 
Loss before income taxes  (3,931)  (3,752)
Income tax benefit  (36)   
Net loss $(3,967) $(3,752)
Net loss per share, basic and diluted $(0.17) $(0.20)
Weighted-average number of shares used to compute net loss per share, basic and diluted  23,854,997   18,557,390 
         


Exagen Inc.
 
Unaudited Condensed Balance Sheets
(in thousands, except share and per share amounts)
 
  March 31, 2026 December 31, 2025
     
Assets    
Current assets:    
Cash and cash equivalents $21,513  $32,220 
Accounts receivable, net  15,773   10,855 
Prepaid expenses and other current assets  6,297   5,818 
Total current assets  43,583   48,893 
Property and equipment, net  6,611   6,938 
Operating lease right-of-use assets  1,179   1,435 
Other assets  584   756 
Total assets $51,957  $58,022 
Liabilities and Stockholders' Equity    
Current liabilities:    
Accounts payable $4,159  $4,153 
Accrued and other current liabilities  4,772   6,327 
Deferred revenue  681   675 
Finance lease liabilities, current  1,113   1,135 
Operating lease liabilities, current  1,259   1,226 
Borrowings, current  580   643 
Total current liabilities  12,564   14,159 
Borrowings, non-current, net of discounts and debt issuance costs  22,291   22,264 
Finance lease liabilities, non-current  1,792   1,960 
Operating lease liabilities, non-current  111   438 
Warrant liability  767   1,752 
Total liabilities  37,525   40,573 
Commitments and contingencies (Note 5)    
Stockholders' equity:    
Preferred stock, $0.001 par value; 10,000,000 shares authorized, no shares issued or outstanding as of March 31, 2026 and December 31, 2025      
Common stock, $0.001 par value; 200,000,000 shares authorized as of March 31, 2026 and December 31, 2025; 24,088,057 and 22,911,575 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively  24   23 
Additional paid-in capital  332,657   331,708 
Accumulated deficit  (318,249)  (314,282)
Total stockholders' equity  14,432   17,449 
Total liabilities and stockholders' equity $51,957  $58,022 
         

Exagen Inc.

Reconciliation of Non-GAAP Financial Measures (UNAUDITED)

The table below presents the reconciliation of adjusted EBITDA, which is a non-GAAP financial measure. See "Use of Non-GAAP Financial Measures (UNAUDITED)" above for further information regarding Exagen's use of non-GAAP financial measures.

  Three Months Ended March 31,
   2026
 2025 
(in thousands)  
Adjusted EBITDA    
Net loss $(3,967) $(3,752)
Other (income) expense  132   (158)
Interest expense  1,267   545 
Change in fair value of warrant liability  (882)   
Income tax expense (benefit)  36    
Depreciation and amortization expense  599   440 
Stock-based compensation expense  655   417 
Adjusted EBITDA (Non-GAAP) $(2,160) $(2,508)



FAQ

How did Exagen (XGN) perform in Q1 2026?

Exagen reported record Q1 2026 revenue of $17.3 million, a 12% year-over-year increase. According to Exagen, AVISE CTD test volume grew 10%, gross margin reached 59.0%, and trailing-twelve-month AVISE CTD ASP rose 6% to $444 per test.

What were Exagen’s Q1 2026 losses and adjusted EBITDA results (XGN)?

Exagen posted a Q1 2026 net loss of $4.0 million and operating loss of $3.4 million. According to Exagen, non-GAAP adjusted EBITDA loss improved to $2.2 million, compared with a $2.5 million adjusted EBITDA loss in the first quarter of 2025.

What guidance did Exagen (XGN) give for full-year 2026 revenue?

Exagen continues to expect full-year 2026 revenue between $70 million and $73 million. According to Exagen, this guidance is unchanged and reflects ongoing growth in AVISE CTD testing and the company’s strategy to expand its autoimmune testing business.

How strong was Exagen’s cash position at the end of Q1 2026 (XGN)?

Exagen ended Q1 2026 with approximately $22 million in cash and cash equivalents. According to Exagen, this cash balance was ahead of expectations and aligns with its long-standing strategy to hold claims in the first quarter of the year.

How did AVISE CTD pricing and volume trend for Exagen in Q1 2026 (XGN)?

AVISE CTD test volume increased 10% year over year in Q1 2026, with ASP also rising. According to Exagen, trailing-twelve-month AVISE CTD average selling price reached $444 per test, up $25, or about 6%, compared to the prior-year period.

What is Exagen’s gross margin for Q1 2026 and how does it compare to 2025 (XGN)?

Exagen reported a Q1 2026 gross margin of 59.0%, slightly above 58.9% in Q1 2025. According to Exagen, this margin performance accompanied higher revenue and growth in AVISE CTD testing, supporting the company’s autoimmune diagnostics business model.