XOMA Royalty Reports 2025 Financial Results and Highlights Recent Business Achievements
Rhea-AI Summary
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Negative
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News Market Reaction – XOMA
On the day this news was published, XOMA gained 1.30%, reflecting a mild positive market reaction. Argus tracked a peak move of +6.4% during that session. Our momentum scanner triggered 7 alerts that day, indicating moderate trading interest and price volatility. This price movement added approximately $5M to the company's valuation, bringing the market cap to $373M at that time.
Data tracked by StockTitan Argus on the day of publication.
Key Figures
Market Reality Check
Peers on Argus
Sector peers showed mixed, mostly modest moves, with only ARCT appearing on the momentum scanner, moving up about 3.13%. No evidence of a coordinated biotech-wide move tied to this earnings release.
Previous Earnings Reports
| Date | Event | Sentiment | Move | Catalyst |
|---|---|---|---|---|
| Nov 12 | Q3 2025 earnings | Positive | -2.5% | Strong Q3 income, cash receipts, and portfolio acquisitions highlighted. |
| Aug 13 | Q2 2025 earnings | Positive | +8.5% | Higher royalties, net income growth, acquisitions, and solid cash balance. |
| May 13 | Q1 2025 earnings | Positive | +10.9% | Sharp income increase, strong cash receipts, and positive net income. |
| Mar 17 | FY 2024 results | Neutral | +0.8% | Portfolio expansion and higher receipts but full-year net loss from credit losses. |
| Nov 07 | Q3 2024 earnings | Negative | -7.0% | Net loss driven by non-cash impairment despite royalty growth and cash strength. |
Earnings releases have generally been viewed positively, with most prior reports leading to aligned price moves, though one notable divergence occurred on a strong Q3 2025 update.
Over the past five earnings-related announcements (Nov 2024–Nov 2025), XOMA Royalty has consistently highlighted growing royalty receipts, expanding acquisition activity, and a strengthening cash position. Several quarters, such as Q1 and Q2 2025, showed solid net income and rising receipts, while 2024 results reflected losses tied to non‑cash items. Today’s full-year 2025 report, with higher income and positive net earnings, continues this trajectory of portfolio expansion and monetization of commercial assets.
Historical Comparison
In the last five earnings updates, XOMA’s average 1-day move was about 2.14%. Today’s 1.47% gain is directionally consistent but somewhat more muted than typical reactions.
Earnings releases over 2024–2025 show a shift from losses driven by non-cash items toward sustained positive income and growing royalty receipts, with portfolio acquisitions and partner late-stage trials steadily adding potential future revenue streams.
Market Pulse Summary
This announcement details substantial growth in 2025 cash receipts, higher income and net earnings, and continued expansion of XOMA’s royalty portfolio through acquisitions and partner progress. Investors may focus on the balance between rising G&A and litigation costs versus growing royalty and milestone streams, as well as key 2026 clinical and regulatory milestones. Monitoring partner trial outcomes, commercialization of OJEMDA and MIPLYFFA, and future deployment of the company’s $133.7 million cash position will be important.
Key Terms
new drug application regulatory
marketing authorization application regulatory
committee for medicinal products for human use regulatory
european medicines agency regulatory
phase 3 medical
breakthrough therapy designation regulatory
six-minute walk distance medical
p = 0.0320 medical
AI-generated analysis. Not financial advice.
Portfolio receipts: • Achieved over
Business development: Added 22 assets to portfolio, including five programs in Phase 2 or Phase 3 development
Stock buyback program: Repurchased and retired 648,048 shares for an aggregate of
Company acquisitions: Completed seven acquisitions, accumulating
Key 2026 pipeline events: • Phase 2b data from volixibat in PSC in Q2 and Phase 3 data from ersodetug in tumor HI in 2H • Potential for EMA decisions on OJEMDA™ and MIPLYFFA™ marketing authorization applications • Regulatory updates related to ersodetug in congenital HI and seralutinib in PAH
Webcast at 8:00 am Eastern Time today
EMERYVILLE, Calif., March 18, 2026 (GLOBE NEWSWIRE) -- XOMA Royalty Corporation (NASDAQ: XOMA), the biotech royalty aggregator, reported its 2025 fourth quarter and full year financial results and highlighted recent actions that have the potential to deliver additional shareholder value.
“We continue to search for innovative ways to drive enhanced optionality in the XOMA portfolio, with the addition of 22 assets and two platform technologies over the past year,” stated Owen Hughes, Chief Executive Officer of XOMA Royalty. “With multiple commercial assets delivering growing royalty receipts, we achieved positive cash flow from operations and were able to return
Portfolio Updates
| Day One |
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| Zevra Therapeutics |
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| Rezolute |
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| Gossamer Bio & Chiesi |
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| Volixibat |
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Business Development Activity
| Takeda Strategic Royalty Share Transaction |
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| Company Acquisitions |
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Fourth Quarter and Full-Year 2025 Financial Results
In the fourth quarter of 2025, XOMA Royalty received
Income and Revenue: Income and revenues for the three months ended December 31, 2025 and 2024, were
General and Administrative (G&A) Expenses: G&A expenses for the three months ended December 31, 2025 and 2024, were
G&A expenses for the year ended December 31, 2025, also include an increase of approximately
XOMA Royalty’s G&A expenses for the three months ended December 31, 2025 and 2024, included non-cash stock-based compensation expenses of
Interest Expense: Interest expense for the three months ended December 31, 2025 and 2024, was
Net Income (Loss): XOMA Royalty reported net income of
Cash Position: On December 31, 2025, XOMA Royalty had cash and cash equivalents of
Webcast
The Company will host a webcast on March 18, 2026, at 8:00 am Eastern Time to discuss the results and provide a business update. The webcast will be accessible on the “News & Events” page in the Investors section of XOMA Royalty’s website (https://investors.xoma.com/news-events). A replay of the webcast will be available for 30 days following the live event.
About XOMA Royalty Corporation
XOMA Royalty is a biotechnology royalty aggregator playing a distinctive role in helping biotech companies achieve their goal of improving human health. XOMA Royalty acquires the potential future economics associated with pre-commercial and commercial therapeutic candidates that have been licensed to pharmaceutical or biotechnology companies. When XOMA Royalty acquires the future economics, the seller receives non-dilutive, non-recourse funding they can use to advance their internal drug candidate(s) or for general corporate purposes. The Company has an extensive and growing portfolio of assets (asset defined as the right to receive potential future economics associated with the advancement of an underlying therapeutic candidate). For more information about the Company and its portfolio, please visit www.xoma.com or follow XOMA Royalty Corporation on LinkedIn.
Forward-Looking Statements/Explanatory Notes
Certain statements contained in this press release are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, including statements regarding the timing and amount of potential commercial payments to XOMA Royalty, expectations around future royalty cash flows covering XOMA Royalty’s core operating expenses (the inflection point) and other developments related to VABYSMO® (faricimab-svoa), OJEMDA™ (tovorafenib), MIPLYFFA™ (arimoclomol), XACIATO™ (clindamycin phosphate) vaginal gel
EXPLANATORY NOTE: Any references to “portfolio” in this press release refer strictly to milestone and/or royalty rights associated with a basket of drug products in development. Any references to “assets” in this press release refer strictly to milestone and/or royalty rights associated with individual drug products in development.
As of the date of this press release, the commercial assets in XOMA Royalty’s milestone and royalty portfolio are VABYSMO® (faricimab-svoa), OJEMDA™ (tovorafenib), MIPLYFFA™ (arimoclomol), XACIATO™ (clindamycin phosphate) vaginal gel
| XOMA ROYALTY CORPORATION | |||||||||||||||
| CONSOLIDATED STATEMENTS OF OPERATIONS | |||||||||||||||
| (in thousands, except per share amounts) | |||||||||||||||
| Three Months Ended December 31, | Year Ended December 31, | ||||||||||||||
| 2025 | 2024 | 2025 | 2024 | ||||||||||||
| Income and revenues: | |||||||||||||||
| Income from purchased receivables under the EIR method | $ | 7,706 | $ | 5,081 | $ | 26,745 | $ | 15,066 | |||||||
| Income from purchased receivables under the cost recovery method | 4,619 | 1,291 | 13,744 | 3,201 | |||||||||||
| Revenue from contracts with customers | 1,100 | 600 | 10,350 | 6,650 | |||||||||||
| Revenue recognized under units-of-revenue method | 332 | 1,742 | 1,310 | 3,570 | |||||||||||
| Total income and revenues | 13,757 | 8,714 | 52,149 | 28,487 | |||||||||||
| Operating expenses: | |||||||||||||||
| Research and development | 281 | 864 | 1,712 | 2,875 | |||||||||||
| General and administrative | 10,410 | 6,993 | 36,092 | 34,478 | |||||||||||
| Credit losses on purchased receivables | — | 7,904 | — | 30,904 | |||||||||||
| Amortization of intangible assets | 884 | 206 | 2,961 | 206 | |||||||||||
| Total operating expenses | 11,575 | 15,967 | 40,765 | 68,463 | |||||||||||
| Income (loss) from operations | 2,182 | (7,253 | ) | 11,384 | (39,976 | ) | |||||||||
| Other income (expense), net: | |||||||||||||||
| Gains on acquisitions | 3,220 | — | 21,224 | 19,316 | |||||||||||
| Change in fair value of embedded derivative related to RPA | — | — | — | 8,100 | |||||||||||
| Interest expense | (3,027 | ) | (3,394 | ) | (13,031 | ) | (13,840 | ) | |||||||
| Other income, net | 3,782 | 1,021 | 12,238 | 6,921 | |||||||||||
| Net income (loss) before tax | 6,157 | (9,626 | ) | 31,815 | (19,479 | ) | |||||||||
| Income tax (expense) benefit | (54 | ) | 5,658 | (103 | ) | 5,658 | |||||||||
| Net income (loss) | $ | 6,103 | $ | (3,968 | ) | $ | 31,712 | $ | (13,821 | ) | |||||
| Net income (loss) available to (attributable to) common stockholders, basic | $ | 3,319 | $ | (5,336 | ) | $ | 18,516 | $ | (19,293 | ) | |||||
| Basic net income (loss) per share available to (attributable to) common stockholders | $ | 0.27 | $ | (0.45 | ) | $ | 1.53 | $ | (1.65 | ) | |||||
| Weighted average shares used in computing basic net income (loss) per share available to (attributable to) common stockholders | 12,208 | 11,868 | 12,081 | 11,701 | |||||||||||
| Net income (loss) available to (attributable to) common stockholders, diluted | $ | 4,679 | $ | (5,336 | ) | $ | 26,184 | $ | (19,293 | ) | |||||
| Diluted net income (loss) per share available to (attributable to) common stockholders | $ | 0.26 | $ | (0.45 | ) | $ | 1.46 | $ | (1.65 | ) | |||||
| Weighted average shares used in computing diluted net income (loss) per share available to (attributable to) common stockholders | 18,095 | 11,868 | 17,982 | 11,701 | |||||||||||
| XOMA ROYALTY CORPORATION | |||||||
| CONSOLIDATED BALANCE SHEETS | |||||||
| (in thousands, except share and per share amounts) | |||||||
| December 31, | December 31, | ||||||
| 2025 | 2024 | ||||||
| ASSETS | |||||||
| Current assets: | |||||||
| Cash and cash equivalents | $ | 82,908 | $ | 101,654 | |||
| Short-term restricted cash | 5,441 | 1,330 | |||||
| Investment in equity securities | 382 | 3,529 | |||||
| Trade and other receivables, net | 4,896 | 1,839 | |||||
| Short-term royalty and commercial payment receivables under the EIR method | 22,780 | 14,763 | |||||
| Short-term royalty and commercial payment receivables under the cost recovery method | - | 413 | |||||
| Prepaid expenses and other current assets | 852 | 2,076 | |||||
| Total current assets | 117,259 | 125,604 | |||||
| Long-term restricted cash | 45,361 | 3,432 | |||||
| Property and equipment, net | 21 | 32 | |||||
| Operating lease right-of-use assets | 256 | 319 | |||||
| Long-term royalty and commercial payment receivables under the EIR method | 4,433 | 4,970 | |||||
| Long-term royalty and commercial payment receivables under the cost recovery method | 55,888 | 55,936 | |||||
| Exarafenib milestone asset | 3,600 | 3,214 | |||||
| Investment in warrants | 697 | — | |||||
| Intangible assets, net | 44,756 | 25,909 | |||||
| Other assets - long term | 427 | 1,861 | |||||
| Total assets | $ | 272,698 | $ | 221,277 | |||
| LIABILITIES AND STOCKHOLDERS’ EQUITY | |||||||
| Current liabilities: | |||||||
| Accounts payable | $ | 2,208 | $ | 1,053 | |||
| Accrued and other liabilities | 9,885 | 5,752 | |||||
| Contingent consideration under RPAs, AAAs, and CPPAs | - | 3,000 | |||||
| Operating lease liabilities | 2,464 | 446 | |||||
| Unearned revenue recognized under units-of-revenue method | 1,268 | 1,361 | |||||
| Preferred stock dividend accrual | 1,424 | 1,368 | |||||
| Current portion of long-term debt | 12,526 | 11,394 | |||||
| Contingent value rights liabilities - current portion | 5,045 | - | |||||
| Total current liabilities | 34,820 | 24,374 | |||||
| Unearned revenue recognized under units-of-revenue method – long-term | 3,193 | 4,410 | |||||
| Exarafenib milestone contingent consideration | 3,600 | 3,214 | |||||
| Long-term operating lease liabilities | 20,114 | 483 | |||||
| Long-term debt | 96,451 | 106,875 | |||||
| Contingent value rights liabilities - long-term | 10,457 | - | |||||
| Deferred tax liability | 103 | - | |||||
| Total liabilities | 168,738 | 139,356 | |||||
| Convertible preferred stock, | 20,019 | 20,019 | |||||
| Stockholders’ equity: | |||||||
| 49 | 49 | ||||||
| — | — | ||||||
| Common stock, | 89 | 90 | |||||
| Additional paid-in capital | 1,305,200 | 1,298,747 | |||||
| Accumulated other comprehensive income | 53 | 73 | |||||
| Accumulated deficit | (1,221,450 | ) | (1,237,057 | ) | |||
| Total stockholders’ equity | 83,941 | 61,902 | |||||
| Total liabilities, convertible preferred stock and stockholders’ equity | $ | 272,698 | $ | 221,277 | |||
| XOMA ROYALTY CORPORATION | |||||||
| CONSOLIDATED STATEMENTS OF CASH FLOWS | |||||||
| (in thousands) | |||||||
| Year Ended December 31, | |||||||
| 2025 | 2024 | ||||||
| Cash flows from operating activities: | |||||||
| Net income (loss) | $ | 31,712 | $ | (13,821 | ) | ||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||||
| Income from purchased receivables under the EIR method | (5,925 | ) | (15,066 | ) | |||
| Stock-based compensation expense | 9,273 | 10,312 | |||||
| Gains on acquisitions | (21,224 | ) | (19,316 | ) | |||
| Credit losses on purchased receivables | — | 30,904 | |||||
| Gain on sale of equity securities | (3,663 | ) | — | ||||
| Income tax expense (benefit) | 103 | (5,658 | ) | ||||
| Common stock contribution to 401(k) | 141 | 118 | |||||
| Amortization of intangible assets | 2,961 | 206 | |||||
| Depreciation | 11 | 10 | |||||
| Accretion of long-term debt discount and debt issuance costs | 1,385 | 1,350 | |||||
| Non-cash lease expense | 64 | 60 | |||||
| Change in fair value of equity securities | (90 | ) | (131 | ) | |||
| Change in fair value of available-for-sale debt securities classified as cash equivalents | (20 | ) | 73 | ||||
| Change in fair value of derivatives | (93 | ) | — | ||||
| CVR liability working capital adjustment | (394 | ) | — | ||||
| Changes in assets and liabilities: | |||||||
| Trade and other receivables, net | (2,426 | ) | (835 | ) | |||
| Prepaid expenses and other assets | 3,839 | 302 | |||||
| Accounts payable and accrued liabilities | (10,597 | ) | 1,598 | ||||
| Operating lease liabilities | (876 | ) | (284 | ) | |||
| Unearned revenue recognized under units-of-revenue method | (1,310 | ) | (3,570 | ) | |||
| Net cash provided by (used in) operating activities | 2,871 | (13,748 | ) | ||||
| Cash flows from investing activities: | |||||||
| Net cash acquired in Kinnate acquisition | — | 18,926 | |||||
| Net cash acquired in Turnstone acquisition | 3,850 | — | |||||
| Net cash and restricted cash acquired in HilleVax acquisition | 46,384 | — | |||||
| Net cash, cash equivalents, and restricted cash acquired in LAVA acquisition | 15,263 | — | |||||
| Net cash and cash equivalents acquired in Mural acquisition | 4,464 | — | |||||
| Payments of consideration under RPAs, AAAs, and CPPAs | (8,000 | ) | (53,000 | ) | |||
| Receipts under RPAs, AAAs, and CPPAs | 3,300 | 29,248 | |||||
| Net payment for IP acquired under the Pulmokine Acquisition | — | (20,176 | ) | ||||
| Payment for BioInvent contract-based intangible asset | (20,725 | ) | — | ||||
| Payment of contingent consideration related to Kinnate IP asset | (550 | ) | — | ||||
| Purchase of property and equipment | — | (20 | ) | ||||
| Purchase of equity securities | (99 | ) | (3,237 | ) | |||
| Sale of equity securities | 6,999 | — | |||||
| Payment to issue short-term loan to Xeno | (5,877 | ) | — | ||||
| Receipt from short-term loan repayment by Xeno | 5,877 | — | |||||
| Net cash provided by (used in) investing activities | 50,886 | (28,259 | ) | ||||
| Cash flows from financing activities: | |||||||
| Proceeds from issuance of common stock | 323 | — | |||||
| Proceeds from issuance of preferred stock | 4,019 | — | |||||
| Payments of preferred and common stock issuance and financing costs | (672 | ) | — | ||||
| Principal payments – debt | (10,598 | ) | (6,902 | ) | |||
| Debt issuance costs and loan fees paid in connection with long-term debt | (80 | ) | (740 | ) | |||
| Payment of preferred stock dividends | (5,472 | ) | (5,472 | ) | |||
| Repurchases of common stock | (16,043 | ) | (13 | ) | |||
| Proceeds from exercise of options and other share-based compensation | 5,046 | 5,214 | |||||
| Taxes paid related to net share settlement of equity awards | (2,986 | ) | (3,214 | ) | |||
| Net cash used in financing activities | (26,463 | ) | (11,127 | ) | |||
| Net increase (decrease) in cash, cash equivalents, and restricted cash | 27,294 | (53,134 | ) | ||||
| Cash, cash equivalents, and restricted cash as of the beginning of the period | 106,416 | 159,550 | |||||
| Cash, cash equivalents, and restricted cash as of the end of the period | $ | 133,710 | $ | 106,416 | |||
| Supplemental Cash Flow Information: | |||||||
| Cash paid for interest | $ | 11,906 | $ | 9,985 | |||
| Cash paid for taxes | $ | 277 | $ | — | |||
| Non-cash investing and financing activities: | |||||||
| Accrual of contingent value rights liability in the Turnstone acquisition | $ | 1,110 | $ | — | |||
| Accrual of contingent value rights liability in the HilleVax acquisition | $ | 5,673 | $ | — | |||
| Accrual of contingent value rights liability in the LAVA acquisition | $ | 9,114 | $ | — | |||
| Right-of-use assets obtained in exchange for operating lease liabilities in the HilleVax acquisition | $ | 22,525 | $ | — | |||
| Relative fair value basis reduction of right-of-use assets in the HilleVax acquisition | $ | (22,525 | ) | $ | — | ||
| Transaction costs in connection with Mural acquisition included in accrued expenses | $ | 320 | $ | — | |||
| Excise tax accrual due to stock repurchases | $ | 68 | $ | — | |||
| Reclassification of equity classified awards to liabilities | $ | (739 | ) | $ | — | ||
| Reclassification of deferred issuance cost to equity | $ | 578 | $ | — | |||
| Preferred stock dividend accrual | $ | 1,424 | $ | 1,368 | |||
| Estimated fair value of the Exarafenib milestone asset | $ | — | $ | 2,922 | |||
| Estimated fair value of the Exarafenib milestone contingent consideration | $ | — | $ | (2,922 | ) | ||
| Right-of-use assets obtained in exchange for operating lease liabilities in the Kinnate acquisition | $ | — | $ | 824 | |||
| Relative fair value basis reduction of rights-of-use assets in the Kinnate acquisition | $ | — | $ | (824 | ) | ||
| Accrual of contingent consideration under the Affitech CPPA | $ | — | $ | 3,000 | |||
| Accrual of contingent consideration under the LadRx AAA | $ | — | $ | 1,000 | |||
| Investor contact: | Media contact: |
| Juliane Snowden | Kathy Vincent |
| XOMA Royalty Corporation | KV Consulting & Management |
| +1-646-438-9754 | kathy@kathyvincent.com |
| juliane.snowden@xoma.com |
1 This amount includes structuring agent fees associated with Repare Therapeutics and ESSA Pharmaceuticals.
2 https://ir.dayonebio.com/news-releases/news-release-details/day-one-reports-fourth-quarter-and-full-year-2025-financial
3 https://www.ipsen.com/press-release/ipsen-receives-positive-chmp-opinion-for-ojemda-for-the-treatment-as-monotherapy-of-children-with-relapsed-or-refractory-braf-altered-pediatric-low-grade-glioma-3246394/
4 https://ir.dayonebio.com/news-releases/news-release-details/servier-and-day-one-biopharmaceuticals-announce-acquisition
5 https://investors.zevra.com/news-releases/news-release-details/zevra-reports-fourth-quarter-and-full-year-2025-financial
6 https://ir.rezolutebio.com/news/detail/371/rezolute-reports-second-quarter-fiscal-2026-financial-results-and-provides-business-update
7 https://ir.gossamerbio.com/news-releases/news-release-details/gossamer-bio-announces-topline-results-phase-3-prosera-study
8 https://ir.mirumpharma.com/news/news-details/2026/Mirum-Pharmaceuticals-Reports-Fourth-Quarter-and-Year-End-2025-Results-and-Provides-Business-Update/default.aspx