Annexon CFO sells 5,565 shares for tax withholding

Annexon, Inc. Executive Vice President and Chief Financial Officer Jennifer Lew reported an open-market sale of 5,565 shares of common stock at a weighted average price of $5.42 per share.

Rhea-AI Filing Summary

Annexon, Inc. Executive Vice President and Chief Financial Officer Jennifer Lew reported an open-market sale of 5,565 shares of common stock at a weighted average price of $5.42 per share. The shares were sold on March 2, 2026 to cover tax withholding obligations tied to vesting restricted stock units. After this tax-related sale, she held 170,700 shares of Annexon common stock directly.

Insider Trade Summary

Net Seller: 5,565 shares

Net Sell 1 txn

Insider Lew Jennifer

Role EVP & CHIEF FINANCIAL OFFICER

Sold 5,565 shs ($30K)

Type	Security	Shares	Price	Value
Sale	Common Stock	5,565	$5.42	$30K

Holdings After Transaction: Common Stock — 170,700 shares (Direct)

Footnotes (2)

1. F1. The shares were sold to cover tax withholding obligations in connection with the vesting of restricted stock units ("RSUs").
2. F2. This transaction was executed in multiple trades in prices ranging from $5.34 to $5.57, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

FAQ

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What insider transaction did Annexon (ANNX) CFO Jennifer Lew report?

Annexon CFO Jennifer Lew reported selling 5,565 shares of common stock in an open-market transaction. The sale related to tax withholding from vesting restricted stock units and left her with 170,700 directly held shares afterward.

Was the Annexon (ANNX) insider sale by Jennifer Lew a discretionary trade?

The filing states the 5,565 Annexon shares were sold to cover tax withholding obligations from vesting restricted stock units. That language indicates the sale was primarily tax-driven, rather than a purely discretionary portfolio decision or broad reduction in ownership.

At what price did Annexon (ANNX) CFO Jennifer Lew sell her shares?

Jennifer Lew’s 5,565 Annexon shares were sold at a weighted average price of $5.42 per share. The trades occurred in multiple executions between $5.34 and $5.57, with full trade-by-trade details available upon request as noted in the filing.

How many Annexon (ANNX) shares does CFO Jennifer Lew own after the reported sale?

Following the tax-related sale, Jennifer Lew directly owns 170,700 shares of Annexon common stock. This post-transaction balance reflects her remaining direct holdings after selling 5,565 shares to satisfy withholding on vesting restricted stock units.

What is the purpose of the Annexon (ANNX) insider sale disclosed in this Form 4?

The Form 4 explains that the 5,565 Annexon shares were sold to cover tax withholding obligations associated with vesting restricted stock units. Such transactions are common when equity awards vest and generate taxable income for the executive.

When did the Annexon (ANNX) insider transaction by Jennifer Lew take place?

The Annexon insider transaction occurred on March 2, 2026, according to the Form 4. On that date, CFO Jennifer Lew executed multiple trades that together sold 5,565 shares at a weighted average price of $5.42 per share.

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Accepted by SEC EDGAR 03/04/2026 - 04:30 PM EST Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Lew Jennifer

(Last) (First) (Middle)

C/O ANNEXON, INC

1400 SIERRA POINT PKWY, BLDG C, STE 200

(Street)

BRISBANE CA 94005

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Annexon, Inc. [ ANNX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	EVP & CHIEF FINANCIAL OFFICER

3. Date of Earliest Transaction (Month/Day/Year)
03/02/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	03/02/2026		S(1)		5,565	D	$5.42(2)	170,700	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The shares were sold to cover tax withholding obligations in connection with the vesting of restricted stock units ("RSUs").

2. This transaction was executed in multiple trades in prices ranging from $5.34 to $5.57, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote.

	/s/ Jennifer Lew	03/04/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.