Empery Asset Management, LP and Ryan M. Lane report beneficial ownership of Annovis Bio, Inc. common stock. They report control over 2,401,476 shares of common stock, representing 5.64% of the class, based on 42,541,868 shares outstanding as of May 19, 2026.
The reporting persons hold no sole voting or dispositive power, but have shared voting and shared dispositive power over the 2,401,476 shares through funds managed by Empery Asset Management. Both Empery and Mr. Lane state that their beneficial ownership is only "deemed" and each disclaims beneficial ownership of shares held by the other reporting person.
Positive
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Key Figures
Beneficially owned shares:2,401,476 sharesPercent of class:5.64%Shares outstanding:42,541,868 shares+2 more
5 metrics
Beneficially owned shares2,401,476 sharesShares of Annovis Bio common stock deemed beneficially owned by the reporting persons
Percent of class5.64%Portion of Annovis Bio common stock represented by 2,401,476 shares
Shares outstanding42,541,868 sharesAnnovis Bio common stock outstanding as of May 19, 2026
Shared voting power2,401,476 sharesShares over which the reporting persons have shared power to vote
Shared dispositive power2,401,476 sharesShares over which the reporting persons have shared power to dispose
"may be deemed to be the beneficial owner of all of the shares"
A beneficial owner is the person who ultimately owns or controls a financial asset or property, even if their name isn't directly on official documents. Think of it like someone who secretly holds the keys to a safe deposit box—others may appear to have access, but the true owner is the one who benefits from what's inside. Identifying beneficial owners helps ensure transparency and prevent illegal activities like money laundering or fraud.
shared voting powerfinancial
"Shared Voting Power 2,401,476.00"
Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.
shared dispositive powerfinancial
"Shared Dispositive Power 2,401,476.00"
investment managerfinancial
"serves as the investment manager to each of the Empery Funds"
percent of classfinancial
"Percent of class: 5.64%"
Percent of class is the portion of a specific category of securities—such as a company’s common shares, preferred shares, or a bond series—that takes part in or approves a corporate action (vote, consent, tender, etc.). Investors watch this number because it reveals how much support or opposition exists within that particular shareholder group; like counting how many members of a club back a proposal, it can determine whether a plan passes or how influence is distributed.
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
How much of Annovis Bio, Inc. (ANVS) does Empery Asset Management report owning?
Empery Asset Management and Ryan M. Lane report beneficial ownership of 2,401,476 shares of Annovis Bio common stock. This represents 5.64% of the company’s outstanding common stock, based on 42,541,868 shares outstanding as of May 19, 2026.
Who are the reporting persons on this Schedule 13G for Annovis Bio (ANVS)?
The reporting persons are Empery Asset Management, LP and Ryan M. Lane. Empery acts as investment manager to the funds holding the shares, and Mr. Lane is the managing member of the entity that ultimately controls the general partner of Empery.
What voting power does Empery have over Annovis Bio (ANVS) shares?
The reporting persons have shared voting power over 2,401,476 shares of Annovis Bio common stock and no sole voting power. Voting authority is exercised through funds for which Empery Asset Management serves as investment manager.
What dispositive power is reported over Annovis Bio (ANVS) shares?
The filing reports shared dispositive power over 2,401,476 shares of Annovis Bio common stock and no sole dispositive power. This means decisions to sell or otherwise dispose of these shares are controlled on a shared basis through the Empery-managed funds.
How was the 5.64% ownership of Annovis Bio (ANVS) calculated?
The 5.64% figure is calculated using 2,401,476 shares deemed beneficially owned divided by an aggregate of 42,541,868 Annovis Bio common shares outstanding as of May 19, 2026, as reported in a company prospectus supplement filed on May 20, 2026.
Does Ryan M. Lane personally claim full beneficial ownership of Annovis Bio (ANVS) shares?
No. Although Mr. Lane may be deemed a beneficial owner through his role over Empery’s general partner, the filing states that each reporting person disclaims beneficial ownership of shares owned by the other reporting person and by the funds.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
Annovis Bio, Inc.
(Name of Issuer)
Common Stock, $0.0001 par value per share
(Title of Class of Securities)
03615A108
(CUSIP Number)
06/30/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
03615A108
1
Names of Reporting Persons
Empery Asset Management, LP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,401,476.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,401,476.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,401,476.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.64 %
12
Type of Reporting Person (See Instructions)
IA, PN
SCHEDULE 13G
CUSIP Number(s):
03615A108
1
Names of Reporting Persons
Ryan M. Lane
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,401,476.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,401,476.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,401,476.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.64 %
12
Type of Reporting Person (See Instructions)
HC, IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Annovis Bio, Inc.
(b)
Address of issuer's principal executive offices:
101 Lindenwood Drive, Suite 225, Malvern, PA 19355
Item 2.
(a)
Name of person filing:
This statement is filed by the entities and persons listed below, who are collectively referred to herein as "Reporting Persons," with respect to Common Stock, $0.0001 par value per share (the "Common Stock") of Annovis Bio, Inc., a Delaware corporation (the "Company"):
(i) Empery Asset Management, LP (the "Investment Manager"), with respect to the Common Stock held by funds to which the Investment Manager serves as investment manager (the "Empery Funds"); and
(ii) Mr. Ryan M. Lane ("Mr. Lane"), with respect to the Common Stock held by the Empery Funds.
The Investment Manager serves as the investment manager to each of the Empery Funds. Mr. Lane (the "Reporting Individual") is the managing member of a limited liability company that is the managing member of Empery AM GP, LLC (the "General Partner"), the general partner of the Investment Manager.
(b)
Address or principal business office or, if none, residence:
The address of the business office of each of the Reporting Persons is:
1 Rockefeller Plaza, Suite 1205
New York, New York 10020
(c)
Citizenship:
Citizenship is set forth in Row 4 of the cover page for each Reporting Person hereto and is incorporated herein by reference for each such Reporting Person.
(d)
Title of class of securities:
Common Stock, $0.0001 par value per share
(e)
CUSIP Number(s):
03615A108
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
The percentage set forth in this Schedule 13G is calculated based upon an aggregate of 42,541,868 shares of Common Stock outstanding as of May 19, 2026, as reported in the Company's Prospectus Supplement filed with the Securities and Exchange Commission pursuant to Rule 424(b)(5) on May 20, 2026.
The Investment Manager, which serves as the investment manager to the Empery Funds, may be deemed to be the beneficial owner of all of the shares of Common Stock held by the Empery Funds. The Reporting Individual, as the managing member of a limited liability company that is the managing member of the General Partner of the Investment Manager with the power to exercise investment discretion, may be deemed to be the beneficial owner of all of the shares of Common Stock held by the Empery Funds. The foregoing should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of the shares of Common Stock owned by another Reporting Person. Each of the Empery Funds and the Reporting Individual hereby disclaims any beneficial ownership of any such Common Stock.
(b)
Percent of class:
5.64%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
(ii) Shared power to vote or to direct the vote:
The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
(iii) Sole power to dispose or to direct the disposition of:
The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
(iv) Shared power to dispose or to direct the disposition of:
The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
See Item 2(a) above.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
