Camp4 Therapeutics Corp received an amended Schedule 13G/A from investment entities affiliated with Vivo Opportunity, reporting significant passive ownership stakes in its common stock. Vivo Opportunity Fund Holdings, L.P. and its general partner Vivo Opportunity, LLC each beneficially own 3,856,991 shares, representing 7.4% of Camp4’s common stock based on 51,880,185 shares outstanding as of December 18, 2025. Vivo Opportunity Cayman Fund, L.P. and its general partner Vivo Opportunity Cayman, LLC each beneficially own 389,577 shares, or 0.8% of the same share base. The filing states that these securities are not held for the purpose of changing or influencing control of Camp4, but rather as passive investments.
Positive
None.
Negative
None.
Insights
Vivo entities report passive stakes totaling notable but minority ownership in Camp4.
The filing shows Vivo Opportunity Fund Holdings, L.P. and its general partner holding 3,856,991 Camp4 common shares, equal to 7.4% of the company, based on 51,880,185 shares outstanding as of December 18, 2025. A Cayman fund complex affiliated with Vivo reports an additional 389,577 shares, or 0.8%.
All entities report sole voting and dispositive power over their respective positions and certify that the holdings were not acquired to change or influence control. This places Vivo as a meaningful but clearly minority shareholder, with influence limited to what such ownership typically confers.
The certification of passive intent and the use of a Schedule 13G/A, rather than a control-oriented filing, frame this as an investment position disclosure. Future ownership updates in subsequent beneficial ownership filings will clarify whether Vivo’s percentage stake increases, decreases, or remains stable over time.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
Camp4 Therapeutics Corp
(Name of Issuer)
Common Stock, par value $0.0001 per share
(Title of Class of Securities)
13463J101
(CUSIP Number)
12/31/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
Vivo Opportunity Fund Holdings, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
3,856,991.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
3,856,991.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
3,856,991.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
7.4 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: The number represents shares of common stock, $0.0001 par value (the "Common Stock") of CAMP4 Therapeutics Corporation (the "Issuer") held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P.
The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the Securities and Exchange Commission ("SEC") pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432).
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
Vivo Opportunity, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
3,856,991.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
3,856,991.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
3,856,991.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
7.4 %
12
Type of Reporting Person (See Instructions)
OO
Comment for Type of Reporting Person: The number represents shares of Common Stock of the Issuer held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P.
The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the SEC pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432).
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
Vivo Opportunity Cayman Fund, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
389,577.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
389,577.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
389,577.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
0.8 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: The number represents shares of Common Stock of the Issuer held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P.
The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the SEC pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432).
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
Vivo Opportunity Cayman, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
389,577.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
389,577.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
389,577.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
0.8 %
12
Type of Reporting Person (See Instructions)
OO
Comment for Type of Reporting Person: The number represents shares of Common Stock of the Issuer held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P.
The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the SEC pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432).
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Camp4 Therapeutics Corp
(b)
Address of issuer's principal executive offices:
One Kendall Square Building 1400 West, 3rd Floor Cambridge, MA 02139
Item 2.
(a)
Name of person filing:
Vivo Opportunity Fund Holdings, L.P. and its General Partner Vivo Opportunity, LLC
Vivo Opportunity Cayman Fund, L.P. and its General Partner Vivo Opportunity Cayman, LLC
(b)
Address or principal business office or, if none, residence:
192 Lytton Avenue, Palo Alto, CA 94301
(c)
Citizenship:
Vivo Opportunity Fund Holdings, L.P. is a Delaware limited partnership.
Vivo Opportunity, LLC is a Delaware limited liability company.
Vivo Opportunity Cayman Fund, L.P. is a Cayman Islands limited partnership.
Vivo Opportunity Cayman, LLC is a Cayman Islands limited liability company.
(d)
Title of class of securities:
Common Stock, par value $0.0001 per share
(e)
CUSIP No.:
13463J101
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Vivo Opportunity, LLC beneficially owns 3,856,991 shares of Common Stock. The securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P.
Vivo Opportunity Cayman, LLC beneficially owns 389,577 shares of Common Stock. The securities are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P.
(b)
Percent of class:
Vivo Opportunity Fund Holdings, L.P.: 7.4%
Vivo Opportunity, LLC: 7.4%
Vivo Opportunity Cayman Fund, L.P.: 0.8%
Vivo Opportunity Cayman, LLC.: 0.8%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
Vivo Opportunity Fund Holdings, L.P.: 3,856,991 shares
Vivo Opportunity, LLC: 3,856,991 shares
Vivo Opportunity Cayman Fund, L.P.: 389,577 shares
Vivo Opportunity Cayman, LLC: 389,577 shares
(ii) Shared power to vote or to direct the vote:
0
(iii) Sole power to dispose or to direct the disposition of:
Vivo Opportunity Fund Holdings, L.P.: 3,856,991 shares
Vivo Opportunity, LLC: 3,856,991 shares
Vivo Opportunity Cayman Fund, L.P.: 389,577 shares
Vivo Opportunity Cayman, LLC: 389,577 shares
(iv) Shared power to dispose or to direct the disposition of:
0
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Vivo Opportunity Fund Holdings, L.P.
Signature:
/s/ Kevin Dai
Name/Title:
Kevin Dai/Managing Member of Vivo Opportunity, LLC, General Partner
Date:
02/13/2026
Vivo Opportunity, LLC
Signature:
/s/ Kevin Dai
Name/Title:
Kevin Dai/Managing Member
Date:
02/13/2026
Vivo Opportunity Cayman Fund, L.P.
Signature:
/s/ Kevin Dai
Name/Title:
Kevin Dai/Managing Member of Vivo Opportunity Cayman, LLC, General Partner
How much of Camp4 Therapeutics Corp (CAMP) does Vivo Opportunity Fund Holdings own?
Vivo Opportunity Fund Holdings, L.P. beneficially owns 3,856,991 Camp4 shares, or 7.4% of the common stock. The percentage is calculated using 51,880,185 shares outstanding as of December 18, 2025, as disclosed in Camp4’s prospectus supplement.
What stake does Vivo Opportunity Cayman Fund, L.P. report in Camp4 Therapeutics Corp (CAMP)?
Vivo Opportunity Cayman Fund, L.P. reports beneficial ownership of 389,577 Camp4 common shares, representing 0.8% of the company. This percentage is also based on 51,880,185 shares outstanding as of December 18, 2025, from Camp4’s prospectus supplement.
Are the Vivo Opportunity entities passive investors in Camp4 Therapeutics Corp (CAMP)?
The Vivo entities certify they are passive investors in Camp4. The Schedule 13G/A states the securities were not acquired and are not held to change or influence control, but rather as investments without a control-related purpose or effect.
Who controls the Camp4 (CAMP) shares held by the Vivo Opportunity entities?
Vivo Opportunity and its Cayman affiliates report sole voting and dispositive power over their Camp4 shares. Each limited partnership’s general partner—Vivo Opportunity, LLC and Vivo Opportunity Cayman, LLC—exercises this authority over the shares held of record by the respective funds.
What share count did Vivo use to calculate its ownership percentage in Camp4 (CAMP)?
The ownership percentages are based on 51,880,185 Camp4 common shares outstanding. This figure comes from Camp4’s prospectus supplement filed December 18, 2025 under Rule 424(b)(5), which is part of the company’s Form S-3 registration statement.
Which entities are included in the Vivo Opportunity Schedule 13G/A for Camp4 (CAMP)?
The filing covers four reporting persons tied to Vivo Opportunity. These are Vivo Opportunity Fund Holdings, L.P., Vivo Opportunity, LLC, Vivo Opportunity Cayman Fund, L.P., and Vivo Opportunity Cayman, LLC, each reporting beneficial ownership stakes in Camp4 common stock.