CollPlant outlines $5M LightSolver computing deal

CollPlant Biotechnologies Ltd. (CLGN) furnished an updated corporate presentation highlighting its LightSolver acquisition and strategy to enter high-performance computing (HPC).

Rhea-AI Filing Summary

CollPlant Biotechnologies Ltd. (CLGN) furnished an updated corporate presentation highlighting its LightSolver acquisition and strategy to enter high-performance computing (HPC). The presentation positions LightSolver’s all-optical “Laser Processing Unit” (LPU) as a future computing platform targeting optimization and simulation workloads in large HPC markets.

The materials describe a transaction structure in which CollPlant provides a public-company platform and resources, including $5 million of funding to LightSolver at closing, plus closing shares and pre-funded warrants and additional warrant tranches tied to specified technology and commercial milestones. CollPlant states it continues to evaluate strategic alternatives for its existing biotech assets with the objective of maximizing shareholder value.

Filing Explained

LightSolver remains pre-commercial: paid programs are in process, while LPU commercial availability remains a 2028 target.

On September 17, 2026, CollPlant furnished an updated presentation about LightSolver. The filing's immediate effect is informational: it describes the acquired business and its commercialization path rather than announcing an additional transaction or completed commercial launch.

The presentation says technical validation is converting into commercial commitment, but lists paid pilots, paid NREs and technical proof-of-concept work as “in process,” while identifying commercial availability of the Laser Processing Unit as a 2028 target. The disclosed state is therefore progress toward commercialization, not commercialization completed.

The performance figures are based partly on emulation and projected future LPU performance, and the presentation says actual results may differ. Its roadmap also states that product specifications and commercial milestones may change.

The specific milestones to monitor are the planned LPU proof of concept in H1 2027, MVP in H2 2027, standard LPU in H1 2028, and the stated 2028 commercial-availability target.

Key Figures

Projected HPC market: $89 billion Serviceable available market for large-scale simulation: $53 billion Funding to LightSolver at closing: $5 million +5 more

8 metrics

Projected HPC market $89 billion Projected high-performance computing market by 2034

Serviceable available market for large-scale simulation $53 billion PDE-based large-scale simulation workloads, part of 2034 HPC market

Funding to LightSolver at closing $5 million Funding commitment from CollPlant to LightSolver to support execution

Variables per LPU core Up to 1,000,000 variables Stated capacity of LightSolver’s all-optical compute core

Projected speed vs GPU Up to 10,000x faster Performance projections for certain workloads compared with a GPU

Power consumption Less than 1 kW Stated power usage for LightSolver’s system

Boeing corrosion modeling speedup Up to 100x faster Projected performance improvement in a Boeing corrosion modeling program

Target commercial availability 2028 Target year for LPU commercial platform availability

Key Terms

high-performance computing, Laser Processing Unit, partial differential equations, paid pilot / NRE, +2 more

6 terms

high-performance computing technical

"Why LightSolver: A Large HPC Opportunity, Proven Technology and a Path to Scale"

A cluster of very powerful computers, special chips and fast networks designed to tackle huge, complex calculations far faster than a normal PC — like replacing a single delivery van with a synchronized fleet to move a city’s worth of packages. For investors, high-performance computing matters because it enables faster product development, more accurate simulations and data analysis, and new revenue streams for hardware, software and services, making firms that supply or use it potentially more competitive and scalable.

Laser Processing Unit technical

"LPU – Laser Processing Unit Using the physics of light itself as a new way to compute"

partial differential equations technical

"Solved partial differential equations (PDEs) Addressing fundamental workloads in engineering"

Partial differential equations are mathematical formulas that describe how a quantity changes across space and time—for example, how heat spreads through a material or how an asset’s price evolves with time and other factors. Investors care because these equations underpin models used to price complex derivatives, estimate risk, and simulate physical or biological systems that affect company value; think of them as detailed recipes that model how many moving parts interact and change.

paid pilot / NRE financial

"Technical Validation Is Converting into Commercial Commitment Benchmark / PoC Paid Pilot / NRE"

serviceable available market financial

"Large-Scale Simulation *PDE-based Workloads 2034 SAM* $53B"

The serviceable available market (SAM) is the portion of the total market that a company can realistically reach with its current products, sales channels and geographic reach. Think of a whole pizza as the overall market and the SAM as the slices you can actually access and sell — it tells investors the near-term revenue opportunity that’s achievable, helping compare potential returns between businesses or strategies.

all-optical compute core technical

"Closed-loop all-optical compute core We use interacting lasers"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does CollPlant Biotechnologies (CLGN) disclose in this Form 6-K?

CollPlant Biotechnologies furnishes an updated corporate presentation that focuses on the LightSolver acquisition, its optical-computing technology, transaction structure, market opportunity in high-performance computing, and CollPlant’s ongoing review of strategic alternatives for its existing biotech assets.

How much funding is CollPlant committing to LightSolver at closing?

CollPlant commits $5 million of funding to LightSolver at closing to support execution. This funding is part of a broader structure that also includes closing shares, pre-funded warrants, and additional warrant tranches tied to specified technology and commercial milestones.

What is the projected high-performance computing market mentioned for CLGN’s LightSolver strategy?

The presentation states that the projected high-performance computing (HPC) market is $89 billion by 2034. Within this, it cites a serviceable available market for large-scale simulation and PDE-based workloads of $53 billion, representing more than 60% of the HPC market.

What performance claims does LightSolver make about its Laser Processing Unit (LPU)?

LightSolver describes its all-optical core as handling up to 1 million variables per core with massively parallel optical interaction and few-nanosecond iterations, and notes projections of being up to 10,000x faster than a GPU for certain workloads, with power consumption under 1 kW.

When does CollPlant expect LightSolver’s LPU platform to be commercially available?

The roadmap in the presentation targets commercial availability of the LPU platform in 2028. It describes prior stages from physics validation in 2022 through scaling the optical core in 2023–2025 and new application classes in 2026, with productization and scaling milestones beyond 2028.

What does CollPlant say about its existing biotech assets in this presentation?

CollPlant states that it continues to evaluate strategic alternatives for its existing biotech assets with the objective of maximizing shareholder value, while LightSolver’s business and technology become the focus of the new corporate presentation.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 09/18/2026 - 08:31 AM Accepted by SEC EDGAR 09/18/2026 - 08:30 AM Learn about SEC filing dates

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

Form 6-K

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16 UNDER

THE SECURITIES EXCHANGE ACT OF 1934

For the month of September 2026

Commission File Number 001-38370

CollPlant Biotechnologies Ltd.

(Exact name of registrant as specified in its charter)

4 Oppenheimer St, Weizmann Science Park

Rehovot 7670104, Israel

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F ☒      Form 40-F ☐

On September 17, 2026, CollPlant Biotechnologies Ltd. has posted to its website an updated corporate presentation. A copy of the presentation is furnished with this Report of Foreign Private Issuer on Form 6-K as Exhibit 99.1 and is incorporated herein by reference.

Attached hereto and incorporated by reference herein are the following exhibits:

99.1 Corporate Presentation.

1

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	COLLPLANT BIOTECHNOLOGIES LTD.
Date: September 18, 2026	By:	/s/ Eran Rotem
		Name:	Eran Rotem
		Title:	Deputy CEO and Chief Financial Officer

2

Exhibit 99.1

1 CollPlant Hosts LightSolver Investor Webinar 17 September 2026

Forward Looking Statements 2 This presentation contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. CollPlant intends such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by words such as "anticipate," "believe," "expect," "intend," "may," "plan," "project," "seek," "should," "will," "estimate," "potential," and similar expressions or their negative forms. These statements include, among others, statements regarding the acquisition of LightSolver, the anticipated benefits and growth opportunities resulting from the transaction, LightSolver's technology and its development and commercialization, potential market opportunities and adoption, technological and commercial milestones, strategic collaborations, and the future business, operations, plans and prospects of CollPlant, LightSolver and the combined business. Forward-looking statements are based on management's current expectations, estimates, assumptions and assessments and are not guarantees of future performance. Actual results may differ materially from those expressed or implied by such statements as a result of various risks and uncertainties, including, among others, the ability to realize the anticipated benefits of the transaction; integration risks; LightSolver's ability to achieve technological and commercial milestones; the development, commercialization and market adoption of LightSolver's technology; competition and technological developments; intellectual property risks; the ability to establish and expand strategic and commercial relationships; the availability of capital; CollPlant's ability to maintain compliance with Nasdaq listing requirements; and general market, industry, economic and geopolitical conditions. Additional risks and uncertainties that could cause actual results to differ materially are described in CollPlant's filings with the U.S. Securities and Exchange Commission, including its most recent Annual Report on Form 20-F and subsequent Reports on Form 6-K. Investors are cautioned not to place undue reliance on forward-looking statements. Forward-looking statements speak only as of the date of this presentation. CollPlant undertakes no obligation to update or revise any forward-looking statements as a result of new information, future events or otherwise, except as required by applicable law.

Why LightSolver: A Large HPC Opportunity, Proven Technology and a Path to Scale 3 CollPlant provides the public -company platform and resources to support commercialization. Applications across major industries Aerospace & Defense · Engineering · Energy · Financial Services · National Labs ~$89B Projected HPC market by 2034 Real-world Customer Validation

Transaction Structure Aligns Ownership with Execution 4 Existing biotech assets CollPlant continues to evaluate strategic alternatives for its existing biotech assets, with the objective of maximizing shareholder value. AT CLOSING Closing shares + pre-funded warrants $5M funding to LightSolver to support execution MILESTONE 1 | MILESTONE 2 | MILESTONE 3 Warrant tranches tied to specified technology and commercial milestones Strategic Alignment Significant potential future ownership is tied to LightSolver's execution and milestone achievement

Computing with Light Dr. Ruti Ben-Shlomi, Co-Founder and CEO

SILICON 6 QUANTUM LIGHT

7 Quantum Nuclear Space We Need More Compute. But We Can't Keep Paying the Energy Bill.

8 What If We Compute With Light? • Closed-loop all-optical compute core • We use interacting lasers • Analog Physical based computer

9 Up to 1M variables / core Massively parallel optical interaction ~200 TB/sec equivalent memory bandwidth Persistent optical memory Few Nanoseconds per iteration Super-fast optical dynamics Up to 10,000x faster than a GPU Reduced data movement Rack size Room temperature < 1 KW Low power consumption Performance figures reflect measured results and projections based on LightSolver 's current systems, emulator, and scaling models. Actual performance may vary. LPU – Laser Processing Unit Using the physics of light itself as a new way to compute

10 A computational problem is translated into laser parameters: For illustrative purposes only. AI model results are preliminary and subject to ongoing development and validation. Inside the LPU: Computing with the Physics of Interacting Lasers

11 Parameters are encoded on laser parameters SLM Mirror Camera For illustrative purposes only. AI model results are preliminary and subject to ongoing development and validation. Inside the LPU: Computing with the Physics of Interacting Lasers

12 The lasers settle into physical equilibrium, the "steady-state" SLM Mirror Camera For illustrative purposes only. AI model results are preliminary and subject to ongoing development and validation. Inside the LPU: Computing with the Physics of Interacting Lasers

13 Camera takes a "snapshot" of the laser values Laser values translated back to digital solution For illustrative purposes only. AI model results are preliminary and subject to ongoing development and validation. Inside the LPU: Computing with the Physics of Interacting Lasers

The Path from Proof to Product 14 •Vision: compute with light •Built core team and optical platform 2020 Founded 2022 Physics is Working •First optical computing demonstrations •Solved optimization problems using only light •Validated the core physics 2023-2025 Scaling the Optical Core •Increased number of variables •Stronger optical core with higher connectivity •Expanded optimization problem types (e.g., SAT, partitioning, portfolio optimization) 2026 New Class of Applications •Solved linear systems (Ax = b) •Solved partial differential equations (PDEs) •Addressing fundamental workloads in engineering and scientific simulation 2028 LPU Commercial Platform •Scaling into the LPU platform •Increasing computational capacity •Expanding to new workloads, including AI •Commercial availability (target 2028)

LightSolver Addresses Some of the World's Largest Compute Markets 15 Large-Scale Simulation *PDE-based Workloads 2034 SAM* $53B >60% of HPC 2034 HPC Market $89B (1) (1) Hyperion Research, 2024 Aerospace & Defense Engineering Software Automotive Oil & Gas Optimization Logistics & Supply Chain Energy & Infrastructure Financial Services AI / Physical A Modeling the Physical World Robotics & Autonomy Drug Discovery & Materials

Technical Validation Is Converting into Commercial Commitment 16 Benchmark / PoC Paid Pilot / NRE Engineering Simulation Leader →up to 50% more accurate mechanical modeling Top-10 Aerospace Company → 60x faster material design Top-25 Defense Company → 10x faster image processing Top-10 Global Bank → 10% more accurate modeling *European Supercomputing Center →up to 10,000x faster linear systems State Owned Defense Company →200x faster decision making Energy Services → 100x faster for Oil & Gas Subsurface Imaging State-owned Defense Company U.S. National Lab European Supercomputing Center U.S. Supercomputing Lab In Process Performance results are based on emulation and projected LPU performance evaluated as part of POC studies and may differ from performance on future commercial systems. *Results based on joint LightSolver -HLRS research published in the ACM Digital Library

Boeing: From POC to a Multi-Year Engineering Program 17 Customer problem: Computationally intensive corrosion modeling Running on LPU platform Performance results are based on emulation and projected LPU performance evaluated as part of POC studies and may differ from performance on future commercial systems. Results: Up to 100x faster Why it Matters: lower fuel consumption Broader Impact: • Better material selection • Lower maintenance burden • Lighter structures lower emissions

Customer Validation and Product Readiness Unlock Scale 18 Product Roadmap Customer Progress H1 27 H2 27 H1 28 H2 28 2029 2030 LPU POC 100K Variables Standard LPU 1M Variables HPC orchestration Enterprise LPU clustering; mass production Simulation tools integration Public cloud partnerships Paid NREs; technical PoCs with labs & industry Roadmap reflects current targets and expectations. Timelines, specifications and commercial milestones are subject to change. Product-ready system Production scaling LPU MVP 100K Variables

19 A Different Compute Paradigm Designed for Real-World Deployment Dimension GPU Quantum Hybrid Photonic LightSolver LPU Compute architecture Electronic massively parallel Quantum + classical control Optical + electronic Closed all-optical loop Target workloads AI / parallel HPC Simulation / optimization AI / matrix operations Simulation / optimization/ * Operating environment Room temperature Specialized; often cryogenic Room temperature Room temperature Maturity Mature Early- stage Emerging Pre-commercial; 2028 target Comparison reflects LightSolver 's assessment based on publicly available information as of September 2026. Technology characteristics, target workloads and maturity vary by implementation and may evolve over time. *AI capabilities are under development.

20 A Full-Stack Technology That Is Difficult to Replicate Proprietary architecture • System know-how • Application expertise Proprietary All-optical architecture Closed-loop computation with interacting lasers Optical System & control know-how Precision control and orchestration Software & algorithms Compiler, PDE and optimization libraries Application & integration know-how Mapping real-world problems onto the LPU Proprietary IP includes patent-pending technologies, software, algorithms, trade secrets and accumulated know-how.

Deep Scientific Leadership. Broader Management Platform. 21 Named a Sample Vendor in Photonic Computing Dr. Ruti Ben Shlomi Co-Founder & CEO PhD in Physics, Weizmann Institute of Science, Intel Eran Rotem Deputy CEO & CFO CollPlant CFO (Nasdaq), Tefron, CFO (NYSE,TASE) Healthcare Tech., CFO (Nasdaq) & Gamida, E&Y Amir Oz COO GE Healthcare, SanDisk Dr. Chene Tradonsky Co-Founder & Chief Scientist PhD in Physics, Weizmann Institute of Science Bar Abelis VP Legal CollPlant (Nasdaq) Goldfarb Gross Seligman

The Investment Case: A New Computing Moving Toward Commercial Scale 22 HPC Megatrend Exposure Next-generation computing that addresses silicon's power and thermal limits. Customer-Validated Tech Active, paid programs with Tier-1 aerospace and defense leaders, including Boeing. Massive Target Workloads Optimization and simulation bottlenecks across a ~$89B+ HPC market. Elite Execution & Leadership Weizmann physicists paired with seasoned Nasdaq executives. Significant Value-Creation Milestones Ahead Productization, customer conversion and commercial scale still lie ahead.

23 Investors@LightSolver.com

Filing Exhibits & Attachments

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• EX-99.1 CORPORATE PRESENTATION 24.4 KB