CRISPR Therapeutics director sells 14,514 shares
The sale price was a weighted average across multiple transactions, with reported prices ranging from $49.45 to $50.44 per share, inclusive.
Sentiment and the balance of points
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Form Type
4
Rhea-AI Filing Summary
CRISPR Therapeutics AG director Simeon George exercised an option for 30,000 Common Shares at an exercise price of $14.0000 per share on October 14, 2026, and sold 14,514 Common Shares that day at a weighted-average price of $49.6330 per share. The sales were effected pursuant to a Rule 10b5-1 trading plan adopted on December 12, 2025.
Indirect holdings listed were 69,687 Common Shares held by SR One Fund II Aggregator, 238,897 held by SR One Opportunities Fund I, and 1,730,179 held by AMZL. George disclaims beneficial ownership of portions held by those entities in which he has no pecuniary interest.
Insider Trade Summary 10b5-1
Exercise and sale activity reported; no spread calculated
Exercise and Sale
6 txns
Insider
George Simeon
Role
Director
Sold
14,514 shs ($720K)
Approx. gross sale proceeds
$720K
Approx. exercise cost
$420K
| Type | Security | Shares | Price | Value |
|---|---|---|---|---|
| Exercise | Stock Option (Right to Buy) F6 | 30,000 | $0.00 | $0.00 |
| Exercise | Common Shares | 30,000 | $14.00 | $420K |
| Sale | Common Shares F1, F2 | 14,514 | $49.633 | $720K |
| holding | Common Shares F3 | -- | -- | -- |
| holding | Common Shares F4 | -- | -- | -- |
| holding | Common Shares F5 | -- | -- | -- |
Holdings After Transaction:
Stock Option (Right to Buy) — 0 contracts (Direct);
Common Shares — 15,486 shares (Direct);
Common Shares — 69,687 shares (Indirect, See Note 3);
Common Shares — 238,897 shares (Indirect, See Note 4);
Common Shares — 1,730,179 shares (Indirect, See Note 5)
Footnotes (6)
- F1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 12, 2025.
- F2. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $49.45 to $50.44 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
- F3. The Reporting Person is the sole managing member of SR One Capital Management, LLC ("SR One Capital Management"), which is the sole general partner of SR One Capital Partners II, LP ("SR One Partners II"). SR One Partners II is the sole general partner of SR One Capital Fund II Aggregator, LP ("SR One Fund II Aggregator"), which is the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership, within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended ("Section 16"), or otherwise of such portion of the securities held by SR One Fund II Aggregator in which the Reporting Person has no pecuniary interest.
- F4. The Reporting Person is the sole managing member of SR One Capital Management, which is the sole general partner of SR One Capital Opportunities Partners I, LP ("SR One Opportunities Partners I"). SR One Opportunities Partners I is the sole general partner of SR One Capital Opportunities Fund I, LP ("SR One Opportunities Fund I"), which is the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership, within the meaning of Section 16 or otherwise of such portion of the securities held by SR One Opportunities Fund I in which the Reporting Person has no pecuniary interest.
- F5. The Reporting Person is the sole managing member of SR One Capital Management, which is the sole general partner of SR One Capital SMA Partners, LP ("SMA Partners"). SMA Partners is the sole general partner of AMZL, LP ("AMZL"), which is the direct beneficial owner of the securities. The Reporting Person disclaims beneficial ownership, within the meaning of Section 16 or otherwise of such portion of the securities held by AMZL in which the Reporting Person has no pecuniary interest.
- F6. This option was granted on October 18, 2016 with respect to 30,000 Common Shares with 100% of the shares vesting in 36 equal monthly installments beginning October 31, 2016.
Key Figures
Option exercise: 30,000 Common Shares
Exercise price: $14.0000 per share
Shares sold: 14,514 Common Shares
+4 more
7 metrics
Option exercise
30,000 Common Shares
October 14, 2026
Exercise price
$14.0000 per share
Option exercised October 14, 2026
Shares sold
14,514 Common Shares
October 14, 2026
Weighted-average sale price
$49.6330 per share
October 14, 2026
Entity-held shares
69,687 Common Shares
Held by SR One Fund II Aggregator; reported October 14, 2026
Entity-held shares
238,897 Common Shares
Held by SR One Opportunities Fund I; reported October 14, 2026
Entity-held shares
1,730,179 Common Shares
Held by AMZL; reported October 14, 2026
Key Terms
Rule 10b5-1 trading plan, weighted average price, beneficial ownership, pecuniary interest
4 terms
Rule 10b5-1 trading plan regulatory
"pursuant to a Rule 10b5-1 trading plan"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
weighted average price financial
"The reported price in Column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
beneficial ownership regulatory
"disclaims beneficial ownership"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
pecuniary interest regulatory
"in which the Reporting Person has no pecuniary interest"
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