[SCHEDULE 13G/A] CryoPort, Inc. SEC Filing

Rhea-AI Filing Summary

Alger Associates, Inc. filed an amendment to Schedule 13G reporting beneficial ownership of 2,358,940 shares of CryoPort, Inc. common stock, representing 4.7% of the outstanding class. The filing states Alger Associates has sole voting and sole dispositive power over these shares and that the securities are held in the ordinary course of business, not for the purpose of changing or influencing control. The filing identifies Fred Alger Management, LLC and Alger Group Holdings as related entities that manage accounts holding the securities.

Positive

• Transparent disclosure of beneficial ownership and related-affiliate structure
• Sole voting and dispositive power over 2,358,940 shares provides clear voting accountability

Negative

• Stake is below 5%, limiting likelihood of material influence on corporate control

Insights

Securities Analyst

TL;DR: Disclosure shows a 4.7% stake with full voting and dispositive authority, indicating a meaningful passive position below the 5% reporting concern.

Alger Associates reports ownership of 2,358,940 shares and affirms ordinary-course holdings rather than an activist intent. The sole voting and dispositive power means the firm can make voting decisions, but at 4.7% the stake remains below the 5% mark that often triggers additional investor scrutiny or strategic expectations. This appears to be a portfolio position managed via affiliated investment vehicles.

Corporate Governance Expert

TL;DR: The filing documents control over votes for a sub-5% position, so governance impact is limited but vote aggregation could matter in close matters.

While Alger Associates asserts sole voting power over 2,358,940 shares, the sub-5% ownership level constrains material influence on corporate control. The certification that holdings are not intended to change control reduces concerns about an imminent proxy campaign. Related-entity disclosures clarify fund and adviser structure, improving transparency for governance assessments.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 3)

Cryoport, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

229050307

(CUSIP Number)

06/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 229050307

1

Names of Reporting Persons

Alger Associates, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

NEW YORK

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 2,358,940.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 2,358,940.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,358,940.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

4.7 %

12

Type of Reporting Person (See Instructions)

HC

Comment for Type of Reporting Person: The securities reported herein are beneficially owned by one or more open-end investment companies or other managed accounts that are investment management clients of Fred Alger Management, LLC ("FAM"), a registered investment adviser. FAM is a 100% owned subsidiary of Alger Group Holdings, LLC ("AGH"), a holding company. AGH is a 100% owned subsidiary of Alger Associates, Inc., a holding company.

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Cryoport, Inc.
(b)	Address of issuer's principal executive offices: 112 Westwood Place, Suite 350, Brentwood, TN 37027
Item 2.
(a)	Name of person filing: Alger Associates, Inc.
(b)	Address or principal business office or, if none, residence: 100 Pearl Street, 27th Floor, New York, NY 10004
(c)	Citizenship: New York
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 229050307
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 2,358,940
(b)	Percent of class: 4.7 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 2,358,940
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 2,358,940
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Ownership of 5 percent or less of a class
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See Exhibit A.
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Alger Associates, Inc.

Signature:	/s/ Hal Liebes
Name/Title:	Hal Liebes / Secretary
Date:	08/14/2025

FAQ

How many CryoPort (CYRX) shares does Alger Associates report owning?

Alger Associates reports beneficial ownership of 2,358,940 shares.

What percentage of CYRX does this ownership represent?

The filing states the position represents 4.7% of the class.

Does Alger Associates have voting control over these shares?

Yes, the filer reports sole voting power and sole dispositive power over the 2,358,940 shares.

Is this filing indicating an attempt to take control of CryoPort?

No; the certification states the securities are held in the ordinary course of business and not acquired to change or influence control.

Who are the related entities mentioned in the filing?

The filing references investment management clients of Fred Alger Management, LLC and holding companies Alger Group Holdings and Alger Associates, Inc.