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  4. [Form 4] Enliven Therapeutics, Inc. Insider Trading Activity

Enliven Therapeutics (ELVN) CMO exercises 5,000 options and sells 5,000 shares

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Enliven Therapeutics, Inc. chief medical officer Helen Louise Collins reported a mix of option exercise and share sales in the company’s stock. On June 17, 2026, she exercised options for 5,000 shares of common stock at a strike price of $2.48 per share, then sold a total of 5,000 shares in three open-market transactions at weighted average prices of $42.8270, $43.8701 and $44.7430 per share. These trades were made under a pre-arranged Rule 10b5-1 trading plan adopted on October 19, 2025. Following the transactions, she holds 30,000 shares of common stock directly and 121,268 stock options.

Positive

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Negative

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Insider Collins Helen Louise
Role CHIEF MEDICAL OFFICER
Sold 5,000 shs ($219K)
Type Security Shares Price Value
Exercise Stock Option (right to buy) 5,000 $0.00 --
Exercise Common Stock 5,000 $2.48 $12K
Sale Common Stock 1,268 $42.827 $54K
Sale Common Stock 2,599 $43.8701 $114K
Sale Common Stock 1,133 $44.743 $51K
Holdings After Transaction: Stock Option (right to buy) — 121,268 shares (Direct, null); Common Stock — 30,000 shares (Direct, null)
Footnotes (1)
  1. The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on October 19, 2025. Certain of these securities are restricted stock units (RSUs). Each RSU represents a contingent right to receive one share of the Issuer's Common Stock. This transaction was executed in multiple trades at prices ranging from $42.295 to $43.2752. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $43.30 to $44.2925. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. This transaction was executed in multiple trades at prices ranging from $44.3005 to $44.95. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. These securities are RSUs. Each RSU represents a contingent right to receive one share of the Issuer's Common Stock. All of the shares subject to this option are fully vested and exercisable as of the date hereof.
Shares sold 5,000 shares Total common stock sold June 17, 2026
Sale prices $42.8270, $43.8701, $44.7430 per share Weighted average prices for three open-market sales
Options exercised 5,000 options Stock option exercise on June 17, 2026
Option strike price $2.48 per share Exercise price for 5,000 stock options
Shares held after 30,000 shares Common stock directly owned following transactions
Options held after 121,268 options Stock options outstanding and fully vested after exercise
Rule 10b5-1 trading plan regulatory
"were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
restricted stock units (RSUs) financial
"Certain of these securities are restricted stock units (RSUs). Each RSU represents a contingent right"
Restricted stock units (RSUs) are a type of company promise to give employees shares of stock in the future, usually after certain conditions like working for a set time. They are like a gift promised today that you receive later, which can become valuable if the company's stock price goes up. RSUs matter because they are a way companies reward employees and can be a significant part of compensation.
weighted average sale price financial
"The price reported above reflects the weighted average sale price."
Stock Option (right to buy) financial
"security_title": "Stock Option (right to buy)""
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Form 4 Insider Transactions: What Each Field Means →
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Collins Helen Louise
(Last)(First)(Middle)
C/O ENLIVEN THERAPEUTICS, INC.
205 PARK ROAD
(Street)
BURLINGAME CALIFORNIA 94010
(City)(State)(Zip)
UNITED STATES
(Country)		2. Issuer Name and Ticker or Trading Symbol
Enliven Therapeutics, Inc. [ ELVN ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
CHIEF MEDICAL OFFICER
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/17/2026		6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/17/2026M(1)5,000A$2.4830,000(2)D
Common Stock06/17/2026S(1)1,268D$42.827(3)28,732(2)D
Common Stock06/17/2026S(1)2,599D$43.8701(4)26,133(2)D
Common Stock06/17/2026S(1)1,133D$44.743(5)25,000(6)D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (right to buy)$2.4806/17/2026M(1)5,000 (7)06/17/2031Common Stock5,000$0121,268D
Explanation of Responses:
1. The option exercise and sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on October 19, 2025.
2. Certain of these securities are restricted stock units (RSUs). Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.
3. This transaction was executed in multiple trades at prices ranging from $42.295 to $43.2752. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
4. This transaction was executed in multiple trades at prices ranging from $43.30 to $44.2925. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
5. This transaction was executed in multiple trades at prices ranging from $44.3005 to $44.95. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price.
6. These securities are RSUs. Each RSU represents a contingent right to receive one share of the Issuer's Common Stock.
7. All of the shares subject to this option are fully vested and exercisable as of the date hereof.
/s/ Ben Hohl, by power of attorney06/22/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

Source: View Original Filing on SEC EDGAR

FAQ

What insider transactions did ELVN’s chief medical officer report?

Helen Louise Collins reported exercising 5,000 stock options at $2.48 and selling 5,000 Enliven Therapeutics common shares in three open-market trades at weighted average prices between $42.8270 and $44.7430, all on June 17, 2026, under a Rule 10b5-1 plan.

How many Enliven Therapeutics (ELVN) shares did the CMO sell?

Helen Louise Collins sold 5,000 shares of Enliven Therapeutics common stock. The sales occurred in three open-market transactions on June 17, 2026, at weighted average prices of $42.8270, $43.8701 and $44.7430 per share, as disclosed in the Form 4 filing.

At what price were the ELVN stock options exercised by the CMO?

The reported stock options were exercised at a strike price of $2.48 per share. This exercise covered 5,000 options, converting them into 5,000 shares of Enliven Therapeutics common stock before the subsequent open-market sales on June 17, 2026.

Were the ELVN insider trades made under a 10b5-1 trading plan?

Yes. The Form 4 states the option exercise and related sales were effected under a Rule 10b5-1 trading plan adopted by Helen Louise Collins on October 19, 2025, indicating the trades were pre-arranged rather than timed discretionarily.

How many Enliven Therapeutics shares does the CMO hold after these trades?

After the reported transactions, Helen Louise Collins holds 30,000 shares of Enliven Therapeutics common stock directly. She also holds 121,268 stock options, all of which are reported as fully vested and exercisable as of the transaction date.

What are RSUs mentioned in the Enliven Therapeutics Form 4 footnotes?

The filing notes that certain securities are restricted stock units, or RSUs. Each RSU represents a contingent right to receive one share of Enliven Therapeutics common stock, meaning the actual shares are delivered only when vesting or other specified conditions are satisfied.