STOCK TITAN

Gyre Therapeutics (GYRE) COO trades 11,000 shares, retains 700,000

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

GYRE THERAPEUTICS, INC. Chief Operating Officer Weiguo Ye reported a series of option exercises paired with open-market sales of common stock. On June 9, 10, and 18, he exercised stock options at $0.75 per share to acquire a total of 11,000 shares of common stock, then sold 11,000 shares in open-market transactions at prices reported around $6.15–$6.35 per share. A footnote states some sales were reported as a weighted average with individual trades between $6.20 and $6.30 per share. After these transactions, Ye directly holds 700,000 shares of Gyre Therapeutics common stock.

Positive

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Negative

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Insider Ye Weiguo
Role Chief Operating Officer
Sold 11,000 shs ($69K)
Type Security Shares Price Value
Exercise Stock Option (Right to Buy) 3,000 $0.00 --
Exercise Common Stock 3,000 $0.75 $2K
Sale Common Stock 3,000 $6.35 $19K
Exercise Stock Option (Right to Buy) 5,000 $0.00 --
Exercise Common Stock 5,000 $0.75 $4K
Sale Common Stock 5,000 $6.24 $31K
Exercise Stock Option (Right to Buy) 3,000 $0.00 --
Exercise Common Stock 3,000 $0.75 $2K
Sale Common Stock 3,000 $6.15 $18K
Holdings After Transaction: Stock Option (Right to Buy) — 827,701 shares (Direct, null); Common Stock — 703,000 shares (Direct, null)
Footnotes (1)
  1. The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $6.20 to $6.30. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price. These options are vested in full.
Shares sold 11,000 shares Total common stock sold in open-market transactions on June 9–18, 2026
Shares acquired via exercise 11,000 shares Common stock acquired by exercising stock options at $0.75 per share
Sale prices $6.15, $6.24, $6.35 per share Per-share prices for common stock sales on June 9, 10 and 18, 2026
Weighted average sale range $6.20–$6.30 per share Range of prices underlying weighted average sale disclosure in footnote
Option exercise price $0.75 per share Conversion or exercise price for stock options exercised into common stock
Shares held after transactions 700,000 shares Direct common stock ownership following June 2026 transactions
Option expiration October 31, 2030 Expiration date shown for the exercised stock options
open-market sale financial
"transaction_action": "open-market sale""
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
Stock Option (Right to Buy) financial
"security_title": "Stock Option (Right to Buy)""
derivative security financial
"transaction_code_description": "Exercise or conversion of derivative security""
A derivative security is a financial contract whose value comes from the price or performance of something else, such as a stock, bond, commodity, or market index. For investors it acts like an insurance policy or a wager: it can be used to protect against losses, lock in prices, or amplify gains and losses, so it can change a portfolio’s risk and potential return without owning the underlying asset directly.
weighted average sale price financial
"The price reported represents the weighted average sale price per share."
vested in full financial
"These options are vested in full."
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Ye Weiguo

(Last)(First)(Middle)
C/O GYRE THERAPEUTICS, INC.
12730 HIGH BLUFF DRIVE, SUITE 250

(Street)
SAN DIEGO CALIFORNIA 92130

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
GYRE THERAPEUTICS, INC. [ GYRE ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
Chief Operating Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/09/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/09/2026M3,000A$0.75703,000D
Common Stock06/09/2026S3,000D$6.15700,000D
Common Stock06/10/2026M5,000A$0.75705,000D
Common Stock06/10/2026S5,000D$6.24(1)700,000D
Common Stock06/18/2026M3,000A$0.75703,000D
Common Stock06/18/2026S3,000D$6.35700,000D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$0.7506/09/2026M3,000 (2)10/31/2030Common Stock3,000$0835,701D
Stock Option (Right to Buy)$0.7506/10/2026M5,000 (2)10/31/2030Common Stock5,000$0830,701D
Stock Option (Right to Buy)$0.7506/18/2026M3,000 (2)10/31/2030Common Stock3,000$0827,701D
Explanation of Responses:
1. The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $6.20 to $6.30. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.
2. These options are vested in full.
/s/ Weiguo Ye06/22/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did GYRE COO Weiguo Ye report?

Weiguo Ye reported exercising stock options to acquire 11,000 GYRE common shares at $0.75 each, then selling 11,000 shares in open-market trades at prices around $6.15–$6.35 per share, according to the Form 4 transactions dated June 9–18, 2026.

How many GYRE shares did the COO sell in the latest Form 4?

The COO sold a total of 11,000 GYRE common shares in open-market transactions. These sales occurred on June 9, 10, and 18, 2026 at reported prices near $6.15, $6.24, and $6.35 per share, as detailed in the Form 4 filing.

At what prices did GYRE COO Weiguo Ye sell common stock?

The Form 4 shows sales of GYRE common stock at per-share prices of $6.15, $6.24, and $6.35. A footnote adds that certain shares were sold at weighted average prices between $6.20 and $6.30, across multiple individual transactions.

What stock options did the GYRE COO exercise in this filing?

Weiguo Ye exercised options covering 11,000 shares of GYRE common stock with a conversion or exercise price of $0.75 per share. The derivative entries describe “Stock Option (Right to Buy)” securities and note that the options referenced are vested in full.

How many GYRE shares does the COO own after these transactions?

After the reported option exercises and stock sales, the Form 4 lists Weiguo Ye as directly holding 700,000 shares of GYRE common stock. This figure reflects his ownership following the June 2026 transactions disclosed in the filing’s non-derivative tables.

Were the GYRE insider stock sales reported as weighted average prices?

Yes. A footnote explains that one set of GYRE stock sales is reported using a weighted average sale price per share, with actual trade prices ranging from $6.20 to $6.30. The COO offers to provide full trade details upon request to specified parties.