Opaleye trims Harrow stake as entities sell 198K shares (HROW)

Rhea-AI Filing Summary

Opaleye Management Inc., a 10% owner of HARROW, INC., reported open-market sales of Harrow common stock through affiliated entities on March 3 and 4, 2026.

Opaleye, L.P. sold 59,000 and 134,000 shares at weighted average prices of $39.1524 and $39.6721, while a separately managed account sold 1,309 and 4,263 shares at the same respective weighted average prices. In total, 198,572 shares were sold in multiple transactions within disclosed price ranges.

Insider Trade Summary

Net Seller: 198,572 shares ($7,846,426)

Net Sell 4 txns

Insider Opaleye Management Inc.

Role 10% Owner

Sold 198,572 shs ($7.85M)

Type	Security	Shares	Price	Value
Sale	Common Stock, par value $0.001 per share	134,000	$39.6721	$5.32M
Sale	Common Stock, par value $0.001 per share	4,263	$39.6721	$169K
Sale	Common Stock, par value $0.001 per share	59,000	$39.1524	$2.31M
Sale	Common Stock, par value $0.001 per share	1,309	$39.1524	$51K

Holdings After Transaction: Common Stock, par value $0.001 per share — 3,622,000 shares (Indirect, By Opaleye, L.P.)

Footnotes (1)

1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Opaleye Management Inc.

(Last) (First) (Middle)

ONE BOSTON PLACE, 26TH FLOOR

(Street)

BOSTON MA 02108

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
HARROW, INC. [ HROW ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
03/03/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, par value $0.001 per share	03/03/2026		S		59,000	D	$39.1524(3)	3,756,000	I	By Opaleye, L.P.(1)(5)
Common Stock, par value $0.001 per share	03/03/2026		S		1,309	D	$39.1524(3)	63,691	I	By Managed Account(2)(5)
Common Stock, par value $0.001 per share	03/04/2026		S		134,000	D	$39.6721(4)	3,622,000	I	By Opaleye, L.P.(1)(5)
Common Stock, par value $0.001 per share	03/04/2026		S		4,263	D	$39.6721(4)	59,428	I	By Managed Account(2)(5)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

3. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $38.50 to $40.66. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.

4. The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $39.12 to $40.50. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price within the range.

5. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

	Opaleye Management Inc., By: /s/ James Silverman, President	03/05/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider activity did Opaleye report for HARROW, INC. (HROW)?

Opaleye reported open-market sales of 198,572 Harrow common shares on March 3 and 4, 2026. The sales were executed through Opaleye, L.P. and a separately managed account, as disclosed in the Form 4 filing.

At what prices were the Harrow (HROW) shares sold by Opaleye entities?

The reported weighted average prices were $39.1524 and $39.6721 per share. Footnotes explain these were weighted averages for multiple trades executed in price ranges between $38.50 and $40.66 on the transaction dates.

How many Harrow (HROW) shares did Opaleye, L.P. sell versus the managed account?

Opaleye, L.P. sold 59,000 shares on March 3 and 134,000 shares on March 4. A separately managed account sold 1,309 shares on March 3 and 4,263 shares on March 4, all reported as open-market sales.

What were Opaleye’s Harrow (HROW) share holdings after these transactions?

After the reported sales, Opaleye, L.P. held 3,756,000 Harrow shares as of March 3 and 3,622,000 shares as of March 4. The managed account held 63,691 shares as of March 3 and 59,428 shares as of March 4.

How does Opaleye describe its beneficial ownership of Harrow (HROW) shares?

The filing states Opaleye Management Inc. may be deemed to beneficially own shares held by Opaleye, L.P. and a managed account. It disclaims beneficial ownership except to the extent of its pecuniary interest, consistent with Section 16 reporting language.

Were the Harrow (HROW) insider sales executed in single trades or multiple trades?

Footnotes explain the reported prices are weighted averages for multiple trades. Shares were sold in numerous transactions within specified price ranges, and detailed trade-level information is available upon request to regulators, the issuer, or its security holders.