LeonaBio: PXV II receives warrants for 2.35M shares

Rhea-AI Filing Summary

LeonaBio, Inc.'s amended ownership disclosure reports that PXV II received Sermonix Pre-Funded Warrants exercisable for 2,352,932 common shares on October 26, 2026, pursuant to a previously disclosed distribution of securities to owners of Sermonix common stock. The warrants are not exercisable to the extent exercise would result in beneficial ownership above 19.99% of LeonaBio's outstanding common stock.

The cover pages list Perceptive Advisors LLC and Joseph Edelman as each beneficially owning 1,889,403 shares (19.99%); Perceptive Life Sciences Master Fund, Ltd. as beneficially owning 1,559,647 shares (16.5%); and PXV II as beneficially owning 359,837 shares (3.8%).

Key Figures

Shares underlying Sermonix Pre-Funded Warrants: 2,352,932 shares Beneficial ownership exercise limit: 19.99% Beneficial ownership reported by Perceptive Advisors LLC and Joseph Edelman: 1,889,403 shares each; 19.99% +2 more

5 metrics

Shares underlying Sermonix Pre-Funded Warrants 2,352,932 shares Received by PXV II on October 26, 2026

Beneficial ownership exercise limit 19.99% Warrants are not exercisable to the extent exercise would exceed this level of LeonaBio common stock ownership

Beneficial ownership reported by Perceptive Advisors LLC and Joseph Edelman 1,889,403 shares each; 19.99% Amounts stated on the reporting persons' cover pages

Beneficial ownership reported by Perceptive Life Sciences Master Fund, Ltd. 1,559,647 shares; 16.5% Amount stated on the reporting person's cover page

Beneficial ownership reported by PXV II 359,837 shares; 3.8% Amount stated on the reporting person's cover page

Key Terms

Sermonix Pre-Funded Warrants, beneficial ownership, Shared Voting Power, Shared Dispositive Power

4 terms

Sermonix Pre-Funded Warrants financial

"received Sermonix Pre-Funded Warrants exercisable for 2,352,932 shares"

beneficial ownership financial

"would result in beneficial ownership in excess of 19.99%"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

Shared Voting Power financial

"Shared Voting Power 1,889,403.00"

Shared voting power occurs when two or more parties jointly have the right to vote or decide how a block of company shares is cast, like co-owners who must agree before moving a piece of furniture. Investors care because who controls voting rights affects board elections, major corporate decisions and takeover outcomes, and shared control can alter regulatory disclosures and the practical influence any holder has over a company’s direction and value.

Shared Dispositive Power financial

"Shared Dispositive Power 1,889,403.00"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many LONA shares are the Sermonix Pre-Funded Warrants exercisable for?

PXV II received warrants exercisable for 2,352,932 LeonaBio common shares on October 26, 2026. The warrants were received pursuant to a previously disclosed distribution of securities to owners of Sermonix common stock.

What beneficial ownership amounts did the LONA reporting persons disclose?

Perceptive Advisors LLC and Joseph Edelman each reported beneficial ownership of 1,889,403 shares (19.99%). Perceptive Life Sciences Master Fund, Ltd. reported 1,559,647 shares (16.5%), and PXV II reported 359,837 shares (3.8%).

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 10/26/2026 - 04:00 PM EDT Accepted by SEC EDGAR 10/26/2026 - 04:00 PM EDT Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 9)

LeonaBio, Inc.

(Name of Issuer)

Common Stock, $0.0001 par value

(Title of Class of Securities)

04746L203

(CUSIP Number)

Alexander Rakitin
Perceptive Advisors LLC, 51 Astor Place, 10th Floor
New York, NY, 10003
(646) 205-5345

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

10/26/2026

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

schemaVersion:

SCHEDULE 13D

CUSIP Number(s): 04746L203

1

Name of reporting person

Perceptive Advisors LLC

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,889,403.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,889,403.00

11

Aggregate amount beneficially owned by each reporting person

1,889,403.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

19.99 %

14

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13D

CUSIP Number(s): 04746L203

1

Name of reporting person

Joseph Edelman

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

AF

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,889,403.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,889,403.00

11

Aggregate amount beneficially owned by each reporting person

1,889,403.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

19.99 %

14

Type of Reporting Person (See Instructions)

IN

SCHEDULE 13D

CUSIP Number(s): 04746L203

1

Name of reporting person

Perceptive Life Sciences Master Fund, Ltd.

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

WC

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

CAYMAN ISLANDS

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 1,559,647.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 1,559,647.00

11

Aggregate amount beneficially owned by each reporting person

1,559,647.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

16.5 %

14

Type of Reporting Person (See Instructions)

CO

SCHEDULE 13D

CUSIP Number(s): 04746L203

1

Name of reporting person

Perceptive Xontogeny Venture Fund II, LP

2

Check the appropriate box if a member of a Group (See Instructions)

(a)
(b)

3

SEC use only

4

Source of funds (See Instructions)

WC

5

Check if disclosure of legal proceedings is required pursuant to Items 2(d) or 2(e)

6

Citizenship or place of organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

7	Sole Voting Power 0.00
8	Shared Voting Power 359,837.00
9	Sole Dispositive Power 0.00
10	Shared Dispositive Power 359,837.00

11

Aggregate amount beneficially owned by each reporting person

359,837.00

12

Check if the aggregate amount in Row (11) excludes certain shares (See Instructions)

13

Percent of class represented by amount in Row (11)

3.8 %

14

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13D

Item 1.	Security and Issuer
(a)	Title of Class of Securities: Common Stock, $0.0001 par value
(b)	Name of Issuer: LeonaBio, Inc.
(c)	Address of Issuer's Principal Executive Offices: 18706 North Creek Parkway, Suite 104, Bothell, WASHINGTON , 98011.
Item 5.	Interest in Securities of the Issuer
(a)	Item 5 of the Schedule 13D is amended and supplemented as follows:
(c)	On October 26, 2026, PXV II received Sermonix Pre-Funded Warrants exercisable for 2,352,932 shares of Common Stock pursuant to the previously disclosed distribution of securities to owners of Sermonix's common stock. The Sermonix Pre-Funded Warrants are not exercisable to the extent that such exercise would result in beneficial ownership in excess of 19.99% of the outstanding shares of Common Stock of the Issuer.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Perceptive Advisors LLC

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Member
Date:	10/26/2026

Joseph Edelman

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman
Date:	10/26/2026

Perceptive Life Sciences Master Fund, Ltd.

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Member
Date:	10/26/2026

Perceptive Xontogeny Venture Fund II, LP

Signature:	/s/ Joseph Edelman
Name/Title:	Joseph Edelman, Managing Partner
Date:	10/26/2026