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LeonaBio (LONA) Financials

LONA NASDAQ
FY2025 annual
Revenue Not reported for FY2025
Net Income -$105.6M n/m YoY
EPS (Diluted) -$24.70 YoY not available
Operating Cash Flow -$45.7M n/m YoY
Market Cap $46.5M as of Oct 30, 2026
Price / Sales n/m no revenue reported
Price / Earnings n/m net loss, so no earnings multiple, FY2025
Price / Book 1.4x on $33.6M equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 30, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 14, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the LONA SEC filings page.

This page shows LeonaBio, Inc. (LONA) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 7 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings.

Rhea AI LONA FY2025

LeonaBio remains cash-consuming with no reported revenue, while 2025 financing coincided with a much more liability-heavy balance sheet.

In FY2024, the net loss of $96.9M closely matched operating cash outflow of $97.2M, but FY2025's $105.6M loss accompanied operating cash outflow of only $45.7M. That widening gap means reported earnings no longer track cash usage closely, pointing to noncash or working-capital effects rather than operating break-even.

With no revenue reported, expense and cash trends are more informative than margin analysis. Research and development fell 75.2% to $17.5M, while selling and administrative expense fell 36.1% to $16.7M; nevertheless, operating loss was $102.3M in FY2025 versus $100.9M in FY2024, so lower spending did not materially reduce the operating deficit.

The balance sheet became more dependent on liabilities: total liabilities rose 361.8% while equity fell 38.0%, leaving liabilities at 69.8% of assets. The current ratio declined from 4.2x to 1.9x, while the company recorded $82.5M of financing cash inflow; the supplied liquidity measure equates reported cash and investments with 23.2 months of the latest annual operating outflow.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Financial health score not available

LeonaBio, Inc. does not currently provide enough eligible data for a peer-relative financial health score, so none is published. The signals and metrics below are current.

Piotroski F-Score Partial
3/6

LeonaBio, Inc. passes 3 of 6 computable financial strength tests (3 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass.

Earnings Quality No Cash Backing
N/A

LeonaBio, Inc. reported a net loss of $105.6M while operations used $45.7M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

EBITDA
-$19.3M
YoYn/m
QoQn/m

LeonaBio, Inc.'s EBITDA was -$19.3M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

Net Income
-$19.0M
YoYn/m
QoQn/m

LeonaBio, Inc. reported a net loss of $19.0M in Q2 2026. The change from the same quarter a year earlier is not meaningful, because that figure was zero or negative. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

EPS (Diluted)
-$0.80
QoQn/m

LeonaBio, Inc. earned -$0.80 per diluted share (EPS) in Q2 2026. The change from the prior quarter is not meaningful, because that quarter’s figure was zero or negative.

Revenue

Not reported for Q2 2026.

Cash & Balance Sheet

Cash & Debt
$32.3M
YoY+62.5%
QoQ-1.6%
5Y CAGR-24.5%

LeonaBio, Inc. held $32.3M in cash as of Q2 2026; no long-term debt figure is on record for that period.

Shares Outstanding
9M
QoQ+0.3%

LeonaBio, Inc. had 9M shares outstanding in Q2 2026. Against the prior quarter it is up 0.3%.

Free Cash Flow

Not reported for Q2 2026.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Return on Equity
-56.6%
YoY-34.8pp
QoQ+10.3pp

LeonaBio, Inc.'s quarterly ROE was -56.6% in Q2 2026: one quarter's net income over shareholder equity, not annualized. This is down 34.8 percentage points from the same quarter a year earlier. Against the prior quarter it is up 10.3 percentage points.

Gross Margin

Not reported for Q2 2026.

Operating Margin

Not reported for Q2 2026.

Net Margin

Not reported for Q2 2026.

Capital Allocation

R&D Spending
$12.7M
YoY+247.0%
QoQ+12.8%

LeonaBio, Inc. invested $12.7M in research and development in Q2 2026. This represents an increase of 247.0% from the same quarter a year earlier. Against the prior quarter it is up 12.8%.

Share Buybacks

Not reported for Q2 2026.

Capital Expenditures

Not reported for Q2 2026.

LONA Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LONA quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'25FilingQ2'2510-QQ1'2510-QQ4'24FilingQ3'24Filing
R&D Expenses$12.7M+247.0%$11.3M+161.8%N/A$2.8M-84.2%$3.7M-83.5%$4.3M-79.7%N/A$17.9M-34.1%
SG&A Expenses$6.6M+81.2%$6.9M+31.5%N/A$4.0M-46.5%$3.6M-38.2%$5.2M-18.9%N/A$7.6M-3.4%
Operating Income-$19.5Mn/m-$17.2Mn/mN/A-$6.9Mn/m-$7.3Mn/m-$9.5Mn/mN/A-$29.6Mn/m
EBITDA-$19.3Mn/m-$17.0Mn/mN/A-$6.7Mn/m-$7.1Mn/m-$9.3Mn/mN/A-$29.4Mn/m
Net Income-$19.0Mn/m-$32.9Mn/mN/A-$6.6Mn/m-$7.0Mn/m-$9.1Mn/mN/A-$28.7Mn/m
EPS (Basic)-$0.80-$1.73-$18.90-$1.68-$1.78-$2.34-$0.39n/m-$7.46
EPS (Diluted)-$0.80-$1.73-$18.90-$1.68-$1.78-$2.34-$0.39n/m-$7.46
Diluted Shares (Avg)24M19MN/A4M4M4MN/A4M

Not reported in any period shown, so not listed: Revenue, Cost of Revenue, Gross Profit, Interest Expense, Income Tax.

LONA Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LONA quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'25FilingQ2'2510-QQ1'2510-QQ4'24FilingQ3'24Filing
Total Assets$56.9M+60.1%$71.6M+64.5%$92.2M+56.8%$30.0M-65.2%$35.5M-68.1%$43.5M-67.4%$58.8M-63.3%$86.2M-53.3%
Current Assets$54.8M+70.1%$69.2M+73.6%$89.5M+63.1%$27.0M-67.0%$32.2M-69.8%$39.9M-69.0%$54.8M-64.6%$82.0M-54.1%
Cash & Equivalents$32.3M+62.5%$32.8M+24.3%$69.3M+43.0%$20.9M-69.7%$19.9M-73.1%$26.4M-66.0%$48.4M-46.5%$68.9M-37.6%
Short-Term Investments$18.7M+88.7%$34.8M+240.0%$19.1M+571.7%$4.4Mn/m$9.9M-44.6%$10.2M-76.8%$2.8M-95.0%$0-100.0%
Long-Term Investments$0n/m$0n/m$0n/m$0n/m$0n/m$0n/m$0n/m$0n/m
Total Liabilities$23.3M+554.7%$22.3M+260.5%$64.4M+361.8%$3.2M-88.7%$3.6M-87.3%$6.2M-76.9%$13.9M-53.6%$28.7M-4.3%
Current Liabilities$7.8M+162.2%$6.7M+21.4%$47.5M+261.7%$2.8M-90.0%$3.0M-88.9%$5.5M-78.5%$13.1M-54.5%$27.8M-3.0%
Non-Current Liabilities$15.5M+2578.5%$15.6M+2160.6%$16.9M+1999.4%$460K-49.6%$578K-43.1%$691K-38.2%$803K-34.0%$912K-30.6%
Total Equity$33.6M+5.0%$49.3M+32.1%$27.8M-38.0%$26.8M-53.5%$32.0M-61.6%$37.3M-65.0%$44.8M-65.6%$57.6M-62.8%
Retained Earnings-$563.7Mn/m-$544.7Mn/m-$511.8Mn/m-$428.9Mn/m-$422.3Mn/m-$415.3Mn/m-$406.1Mn/m-$391.1Mn/m

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

LONA Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LONA quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'25FilingQ2'2510-QQ1'2510-QQ4'24FilingQ3'24Filing
Operating Cash Flow-$17.0Mn/m-$20.9Mn/m-$19.4Mn/m-$4.7Mn/m-$7.0Mn/m-$14.7Mn/m-$26.0Mn/m-$23.0Mn/m
Depreciation & Amortization$200K0.0%$231K-4.9%$243K0.0%$200K0.0%$200K0.0%$243K+0.4%$243K-0.8%$200K-18.0%
Stock-Based Compensation$3.2M+99.2%$662K-59.6%N/A$1.4M-52.0%$1.6M-50.2%$1.6M-38.9%N/A$2.9M+17.7%
Capital ExpendituresN/AN/AN/AN/AN/AN/A$0n/m$0-100.0%
Free Cash FlowN/AN/AN/AN/AN/AN/A-$26.0Mn/m-$23.0Mn/m
Investing Cash Flow$16.3M+3603.9%-$15.5Mn/m-$14.6Mn/m$5.7M-68.7%$441K-98.3%-$7.4M-156.4%-$2.8M-144.0%$18.0M-12.8%
Financing Cash FlowN/AN/A$82.4M+242361.8%$0-100.0%N/AN/A$34K-77.6%$12Kn/m

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

LONA Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

LONA quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'25FilingQ2'2510-QQ1'2510-QQ4'24FilingQ3'24Filing
Return on Equity-56.6%-34.8pp-66.8%-42.3ppN/A-24.7%+25.2pp-21.8%+10.4pp-24.5%+0.2ppN/A-49.9%-28.6pp
Return on Assets-33.4%-13.8pp-46.0%-25.0ppN/A-22.0%+11.3pp-19.6%+4.5pp-21.0%-1.3ppN/A-33.3%-15.5pp
Current Ratio7.01-3.8x10.38+3.1x1.88-2.3x9.70+6.7x10.81+6.8x7.26+2.2x4.18-1.2x2.95-3.3x
Liabilities-to-Equity0.69+0.6x0.45+0.3x2.32+2.0x0.12-0.4x0.11-0.2x0.17-0.1x0.31+0.1x0.50+0.3x

Not reported in any period shown, so not listed: Gross Margin, Operating Margin, Net Margin, Debt-to-Equity, Asset Turnover, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it. Market cap is stated at each company's latest close.

Company Fiscal year Revenue Net income Net margin Market cap Health score
LeonaBio, Inc. LONA FY2025 N/A -$105.6M N/A $46.5M —
Biomea Fusion, Inc. BMEA FY2025 N/A -$61.8M N/A $46.4M —
Kalaris Therapeutics, Inc. KLRS FY2025 N/A -$43.4M N/A $48.3M —
Annovis Bio, Inc. ANVS FY2025 $0 -$28.9M N/A $48.2M —
ImageneBio, Inc. IMA FY2025 $800K -$45.3M N/A $46.5M —
Werewolf Therapeutics, Inc. HOWL FY2025 N/A -$60.8M N/A $47.9M —

Frequently Asked Questions

Is LeonaBio, Inc. profitable?

No, LeonaBio, Inc. (LONA) reported a net loss of $105.6M in fiscal year 2025.

What is LeonaBio, Inc.'s earnings per share (EPS)?

LeonaBio, Inc. (LONA) reported diluted earnings per share of -$24.70 for fiscal year 2025. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

What is LeonaBio, Inc.'s EBITDA?

LeonaBio, Inc. (LONA) had EBITDA of -$101.3M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

LeonaBio, Inc. (LONA) has a return on equity of -380.0% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

LeonaBio, Inc. (LONA) recorded an outflow of $45.7M in operating cash flow during fiscal year 2025, representing cash used by core business activities.

LeonaBio, Inc. (LONA) had $92.2M in total assets as of fiscal year 2025, including both current and long-term assets.

LeonaBio, Inc. (LONA) invested $17.5M in research and development during fiscal year 2025.

LeonaBio, Inc. (LONA) had 9M shares outstanding as of fiscal year 2025.

LeonaBio, Inc. (LONA) had a current ratio of 1.88 as of fiscal year 2025, which is generally considered healthy.

LeonaBio, Inc. (LONA) had a liabilities-to-equity ratio of 2.32 as of fiscal year 2025, which is total liabilities divided by total shareholder equity. Total liabilities counts every obligation on the balance sheet (payables, deposits, insurance reserves and deferred taxes as well as borrowings), so this ratio usually runs well above debt-to-equity. No debt-to-equity ratio is shown for fiscal year 2025, because the filing data we hold for that year carries no long-term debt figure.

LeonaBio, Inc. (LONA) had a return on assets of -114.6% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

LeonaBio, Inc. (LONA) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $46.5M as of Oct 30, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

LeonaBio, Inc. (LONA) has no price-to-sales ratio at the moment: no revenue reported. The market capitalization is $46.5M as of Oct 30, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

At the end of fiscal year 2025, LeonaBio, Inc. (LONA) held $88.3M in cash, cash equivalents and investments, and reported an operating cash outflow of $45.7M over that year. Dividing the one by the other, the reported balance equals about 23 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

LeonaBio, Inc. (LONA) has a Piotroski F-Score of 3 out of 6 computable signals; 3 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

LeonaBio, Inc. (LONA) reported a net loss of $105.6M while operations used $45.7M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

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