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Deerfield-linked director entity reports 3,444 Nuvalent (NUVL) RSUs and large holdings

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Flynn James E reported acquisition or exercise transactions in this Form 4 filing.

Nuvalent, Inc. reported an updated insider position for entities affiliated with Deerfield Management Company, L.P., highlighting a new equity award tied to board service. On June 16, 2026, 3,444 restricted stock units (RSUs) were granted to director Cameron Wheeler, which are held for the benefit and at the direction of Deerfield Management.

Each RSU represents one share of Nuvalent Class A common stock and vests in full on the earlier of June 16, 2027 or the company’s next annual stockholder meeting, subject to Wheeler’s continued service. The filing also lists indirect Class A common stock holdings through several Deerfield funds, including 8,299,225 shares through Deerfield Healthcare Innovations Fund, L.P., 650,000 shares through Deerfield Partners, L.P., and 10,292 shares through Deerfield Management Company, L.P. The reporting persons disclaim beneficial ownership except to the extent of any indirect pecuniary interest.

Positive

  • None.

Negative

  • None.
Insider Flynn James E, DEERFIELD MANAGEMENT COMPANY, L.P.
Role null | null
Type Security Shares Price Value
Grant/Award Class A Common Stock 3,444 $0.00 --
holding Class A Common Stock -- -- --
holding Class A Common Stock -- -- --
holding Class A Common Stock -- -- --
holding Class A Common Stock -- -- --
Holdings After Transaction: Class A Common Stock — 3,444 shares (Indirect, Through Deerfield Management Company, L.P.)
Footnotes (1)
  1. Cameron Wheeler, a partner in Deerfield Management Company, L.P. ("Deerfield Management"), serves as a director of the Issuer. The reported shares of Class A Common Stock are issuable under restricted stock units ("RSUs") granted to Dr. Wheeler, which are held for the benefit, and at the direction, of Deerfield Management. Each RSU represents the right to receive one share of the Issuer's Class A Common Stock. The RSUs vest in full on the earlier of June 16, 2027 or the date of the Issuer's next annual meeting of stockholders, subject to Mr. Wheeler's continued service to the Issuer through the applicable vesting date. This Form 4 is being filed by the undersigned as well as the entity listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt IV, L.P. is the general partner of Deerfield Private Design Fund IV, L.P. ("Fund IV"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Deerfield Partners and Fund IV, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt IV, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise. Represents shares underlying fully vested restricted stock units originally issued to Dr. Wheeler and Joseph Pearlberg (who formerly served as a director of the Issuer), which shares are held for the benefit, and at the direction, of Deerfield Management.
RSU grant 3,444 RSUs Granted June 16, 2026 to director, held for Deerfield Management
RSU vesting date June 16, 2027 RSUs vest on earlier of June 16, 2027 or next annual meeting
Deerfield Healthcare Innovations Fund holding 8,299,225 shares Indirect Class A common stock holding through Deerfield Healthcare Innovations Fund, L.P.
Deerfield Partners holding 650,000 shares Indirect Class A common stock holding through Deerfield Partners, L.P.
Deerfield Management holding 10,292 shares Indirect Class A common stock holding through Deerfield Management Company, L.P.
RSU grant price $0.0000 per share RSUs reported with zero purchase price as a grant/award acquisition
restricted stock units financial
"The reported shares of Class A Common Stock are issuable under restricted stock units ("RSUs") granted to Dr. Wheeler"
Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.
pecuniary interest financial
"each Reporting Person disclaims beneficial ownership ... except to the extent of his/its indirect pecuniary interest therein"
Section 16 regulatory
"For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership"
Section 16 is a U.S. securities law rule that governs the trading and disclosure obligations of company insiders — typically officers, directors and large shareholders — to promote transparency and deter unfair profit-taking. It requires insiders to publicly report their stock trades and allows companies or the issuer to reclaim quick, short-term profits from certain insider trades, like a scoreboard and a refund policy that help investors see and limit possible insider advantage.
director by deputization regulatory
"other: Director by Deputization"
indirect ownership financial
"nature_of_ownership: Through Deerfield Healthcare Innovations Fund, L.P."
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Flynn James E

(Last)(First)(Middle)
345 PARK AVENUE SOUTH, 12TH FLOOR

(Street)
NEW YORK NEW YORK 10010

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Nuvalent, Inc. [ NUVL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirectorX10% Owner
Officer (give title below)XOther (specify below)
Director by Deputization
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/16/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Class A Common Stock06/16/2026A3,444(1)A$03,444(1)IThrough Deerfield Management Company, L.P.(1)(2)(3)
Class A Common Stock10,292IThrough Deerfield Management Company, L.P.(2)(3)(4)
Class A Common Stock650,000IDeerfield Partners, L.P.(2)(3)
Class A Common Stock8,299,225IThrough Deerfield Private Design Fund IV, L.P.(2)(3)
Class A Common Stock8,299,225IThrough Deerfield Healthcare Innovations Fund, L.P.(2)(3)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
1. Name and Address of Reporting Person*
Flynn James E

(Last)(First)(Middle)
345 PARK AVENUE SOUTH, 12TH FLOOR

(Street)
NEW YORK NEW YORK 10010

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)XOther (specify below)
Director by Deputization
1. Name and Address of Reporting Person*
DEERFIELD MANAGEMENT COMPANY, L.P.

(Last)(First)(Middle)
345 PARK AVENUE SOUTH, 12TH FLOOR

(Street)
NEW YORK NEW YORK 10010

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)XOther (specify below)
Director by Deputization
Explanation of Responses:
1. Cameron Wheeler, a partner in Deerfield Management Company, L.P. ("Deerfield Management"), serves as a director of the Issuer. The reported shares of Class A Common Stock are issuable under restricted stock units ("RSUs") granted to Dr. Wheeler, which are held for the benefit, and at the direction, of Deerfield Management. Each RSU represents the right to receive one share of the Issuer's Class A Common Stock. The RSUs vest in full on the earlier of June 16, 2027 or the date of the Issuer's next annual meeting of stockholders, subject to Mr. Wheeler's continued service to the Issuer through the applicable vesting date.
2. This Form 4 is being filed by the undersigned as well as the entity listed on the Joint Filer Information Statement attached as an exhibit hereto (the "Reporting Persons"). Deerfield Mgmt, L.P. is the general partner of Deerfield Partners, L.P. ("Deerfield Partners"). Deerfield Mgmt IV, L.P. is the general partner of Deerfield Private Design Fund IV, L.P. ("Fund IV"). Deerfield Mgmt HIF, L.P. is the general partner of Deerfield Healthcare Innovations Fund, L.P. (collectively with Deerfield Partners and Fund IV, the "Funds"). Deerfield Management Company, L.P. is the investment manager of the Funds. James E. Flynn is the sole member of the general partner of each of Deerfield Mgmt, L.P., Deerfield Mgmt IV, L.P., Deerfield Mgmt HIF, L.P. and Deerfield Management Company, L.P.
3. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each Reporting Person disclaims beneficial ownership of any such securities, except to the extent of his/its indirect pecuniary interest therein, if any, and this report shall not be deemed an admission that such Reporting Person is the beneficial owner of such securities for purposes of Section 16 or otherwise.
4. Represents shares underlying fully vested restricted stock units originally issued to Dr. Wheeler and Joseph Pearlberg (who formerly served as a director of the Issuer), which shares are held for the benefit, and at the direction, of Deerfield Management.
Remarks:
Cameron Wheeler, a partner in Deerfield Management, serves as a director of the Issuer. Jonathan Isler, Attorney-in-Fact: Power of Attorney, which is hereby incorporated by reference to Exhibit 24 to a Form 3 with regard to BiomX Inc. filed with the Securities and Exchange Commission on March 19, 2024 by Deerfield Private Design Fund V, L.P., Deerfield Healthcare Innovations Fund II, L.P., Deerfield Mgmt V, L.P., Deerfield Mgmt HIF II, L.P., Deerfield Management Company, L.P. and James E. Flynn.
/s/ Jonathan Isler, Attorney-in-Fact06/18/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transaction did Nuvalent (NUVL) report in this Form 4?

Nuvalent reported a grant of 3,444 restricted stock units linked to director Cameron Wheeler, held for the benefit of Deerfield Management. The award represents Class A common stock and is reported as an indirect acquisition, not an open‑market purchase or sale.

Who effectively benefits from the new Nuvalent (NUVL) RSU grant?

The 3,444 RSUs were granted to director Cameron Wheeler but are held for the benefit, and at the direction, of Deerfield Management Company, L.P. The reporting persons disclaim beneficial ownership beyond any indirect pecuniary interest described in the filing’s footnotes.

When do the 3,444 Nuvalent (NUVL) RSUs vest for the Deerfield-affiliated director?

The 3,444 restricted stock units vest in full on the earlier of June 16, 2027 or Nuvalent’s next annual stockholder meeting. Vesting is conditioned on Cameron Wheeler’s continued service to Nuvalent through the applicable vesting date, according to the filing.

How many Nuvalent (NUVL) shares are held through Deerfield Healthcare Innovations Fund?

The filing shows 8,299,225 shares of Nuvalent Class A common stock held indirectly through Deerfield Healthcare Innovations Fund, L.P. This is one of several Deerfield-related entities listed, each reported as indirect ownership with Section 16 beneficial ownership disclaimers.