STOCK TITAN

BeOne Medicines (ONC) CEO sells 64,628 ADS after exercising options

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

BeOne Medicines Ltd. director and CEO John Oyler exercised options to acquire 64,628 American Depositary Shares (ADS), representing 840,164 Ordinary Shares, at $119.96 per ADS, and then sold 64,628 ADS in multiple open-market transactions at weighted-average prices, with execution prices ranging from $304.96 to $315.18 per ADS, pursuant to a Rule 10b5-1 trading plan adopted on March 10, 2026. Following these transactions, he directly holds 5,445,917 Ordinary Shares, and the filing also lists substantial indirect holdings in various trusts and Oyler Investment LLC, for which beneficial ownership is disclaimed, as well as 9,545,000 Ordinary Shares held for his benefit in a Roth IRA.

Positive

  • None.

Negative

  • None.
Insider OYLER JOHN
Role Chief Executive Officer
Sold 64,628 shs ($20.16M)
Type Security Shares Price Value
Exercise Share Option (Right to Buy) 840,164 $0.00 --
Exercise American Depositary Shares 64,628 $119.96 $7.75M
Sale American Depositary Shares 1,440 $305.1985 $439K
Sale American Depositary Shares 597 $306.9642 $183K
Sale American Depositary Shares 680 $309.0541 $210K
Sale American Depositary Shares 4,833 $310.3694 $1.50M
Sale American Depositary Shares 5,543 $311.423 $1.73M
Sale American Depositary Shares 35,829 $312.1748 $11.18M
Sale American Depositary Shares 14,915 $313.1879 $4.67M
Sale American Depositary Shares 740 $314.3198 $233K
Sale American Depositary Shares 51 $315.0624 $16K
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
holding Ordinary Shares -- -- --
Holdings After Transaction: Share Option (Right to Buy) — 441,870 shares (Direct); American Depositary Shares — 64,628 shares (Direct); Ordinary Shares — 5,445,917 shares (Direct); Ordinary Shares — 481,533 shares (Indirect, See Footnote)
Footnotes (1)
  1. These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership. These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. These securities are held by Oyler Investment LLC, of which 99% of the the limited liability company interests are owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership. These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account. These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's child, for which the Reporting Person disclaims beneficial ownership. Each American Depositary Share represents 13 Ordinary Shares. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.96 to $305.605, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.61 to $307.59, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $308.77 to $309.37, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $309.78 to $310.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $310.78 to $311.77, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $311.78 to $312.77, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $312.78 to $313.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.83 to $314.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $314.88 to $315.18, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price. The number of securities underlying each option and the exercise price therefore are represented in ordinary shares. These securities vest over a four-year period as follows: 25% on June 5, 2020, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.
ADS sold 64,628 American Depositary Shares Total ADS sold by John Oyler on 2026-07-17 across multiple transactions
Options exercised (Ordinary Shares) 840,164 Ordinary Shares Shares underlying options exercised and converted into 64,628 ADS
ADS exercise price $119.9600 per ADS Price per ADS for the non-derivative acquisition related to the option exercise
Option exercise price $9.2300 per Ordinary Share Exercise price of Share Options (represented in Ordinary Shares)
Direct Ordinary Shares held 5,445,917 Ordinary Shares Direct BeOne Medicines holdings reported for John Oyler after transactions
Roth IRA holdings 9,545,000 Ordinary Shares Ordinary Shares held for Oyler’s benefit in a Roth IRA PENSCO trust account
Unexercised Share Options 441,870 options Share Options remaining outstanding after partial exercise, expiring June 4, 2029
American Depositary Share financial
"Each American Depositary Share represents 13 Ordinary Shares."
An American Depositary Share (ADS) is a U.S.-listed certificate that represents a specified number of shares in a foreign company, held by a custodian bank; it works like a receipt that allows U.S. investors to buy and trade foreign equity on American exchanges without dealing with another country’s markets. Investors care because ADSs make foreign stocks easier to access, improve liquidity and settlement in dollars, and can affect dividend payments, voting rights and regulatory oversight compared with buying the underlying foreign shares directly.
Rule 10b5-1 trading plan regulatory
"The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person..."
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
grantor retained annuity trust financial
"These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee..."
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
weighted average price financial
"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions..."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
Share Option (Right to Buy) financial
"Share Option (Right to Buy) ... underlying security title Ordinary Shares"

AI-generated analysis. How Rhea-AI works. Not financial advice.

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FAQ

What insider transactions did BeOne Medicines (ONC) CEO John Oyler report on July 17, 2026?

John Oyler reported exercising options into 64,628 American Depositary Shares and then selling the same 64,628 ADS in multiple open-market transactions. All reported sales were made under a pre-arranged Rule 10b5-1 trading plan adopted on March 10, 2026.

At what prices did John Oyler sell BeOne Medicines (ONC) American Depositary Shares?

The ADS sales were reported at weighted-average prices, with execution prices ranging from $304.96 to $315.18 per ADS. Each sale block’s price is disclosed as a weighted average, with detailed per-trade pricing available from the company or the SEC upon request.

What BeOne Medicines (ONC) shareholdings does John Oyler have after these transactions?

After the reported trades, John Oyler directly holds 5,445,917 Ordinary Shares. The filing also shows 9,545,000 Ordinary Shares held for his benefit in a Roth IRA and additional large positions in several trusts and an LLC, for which he disclaims beneficial ownership.

What options did John Oyler exercise in this BeOne Medicines (ONC) Form 4 filing?

Oyler exercised 840,164 Share Options into 840,164 Ordinary Shares (64,628 ADS) at an exercise price of $9.23 per Ordinary Share. After this partial exercise, 441,870 Share Options remain outstanding, expiring on June 4, 2029.

Was John Oyler’s BeOne Medicines (ONC) ADS selling activity discretionary or under a plan?

The ADS sales were conducted under a Rule 10b5-1 trading plan adopted by John Oyler on March 10, 2026. Such plans pre-schedule trades, so the timing of these transactions is governed by the plan’s terms rather than day-to-day trading decisions.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
OYLER JOHN

(Last)(First)(Middle)
C/O BEONE MEDICINES I GMBH
AESCHENGRABEN 27, 21ST FLOOR

(Street)
BASEL4051

(City)(State)(Zip)

SWITZERLAND

(Country)
2. Issuer Name and Ticker or Trading Symbol
BeOne Medicines Ltd. [ ONC ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Chief Executive Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
07/17/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares5,445,917D
Ordinary Shares481,533ISee Footnote(1)
Ordinary Shares7,699,158ISee Footnote(2)
Ordinary Shares28,204,115ISee Footnote(3)
Ordinary Shares9,545,000ISee Footnote(4)
Ordinary Shares102,188ISee Footnote(5)
American Depositary Shares(6)07/17/2026M64,628A$119.9664,628D
American Depositary Shares(6)07/17/2026S(7)1,440D$305.1985(8)63,188D
American Depositary Shares(6)07/17/2026S(7)597D$306.9642(9)62,591D
American Depositary Shares(6)07/17/2026S(7)680D$309.0541(10)61,911D
American Depositary Shares(6)07/17/2026S(7)4,833D$310.3694(11)57,078D
American Depositary Shares(6)07/17/2026S(7)5,543D$311.423(12)51,535D
American Depositary Shares(6)07/17/2026S(7)35,829D$312.1748(13)15,706D
American Depositary Shares(6)07/17/2026S(7)14,915D$313.1879(14)791D
American Depositary Shares(6)07/17/2026S(7)740D$314.3198(15)51D
American Depositary Shares(6)07/17/2026S(7)51D$315.0624(16)0D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Share Option (Right to Buy)$9.23(17)07/17/2026M840,164 (18)06/04/2029Ordinary Shares840,164$0441,870D
Explanation of Responses:
1. These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.
2. These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
3. These securities are held by Oyler Investment LLC, of which 99% of the the limited liability company interests are owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
4. These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.
5. These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's child, for which the Reporting Person disclaims beneficial ownership.
6. Each American Depositary Share represents 13 Ordinary Shares.
7. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.
8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.96 to $305.605, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.61 to $307.59, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $308.77 to $309.37, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $309.78 to $310.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $310.78 to $311.77, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $311.78 to $312.77, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
14. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $312.78 to $313.76, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
15. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.83 to $314.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
16. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $314.88 to $315.18, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
17. The number of securities underlying each option and the exercise price therefore are represented in ordinary shares.
18. These securities vest over a four-year period as follows: 25% on June 5, 2020, and the remaining in 36 successive equal monthly installments, subject to continued service. Unvested shares are subject to accelerated vesting upon a change in control or certain termination events.
Remarks:
/s/ Frank Collazo, as Attorney-in-Fact07/17/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)