Ameriprise Financial (NYSE: AMP) discloses 7.1% ownership in Personalis (PSNL)

Rhea-AI Filing Summary

Ameriprise Financial, Inc. filed a Schedule 13G reporting a significant ownership stake in Personalis, Inc. common stock. As of 12/31/2025, Ameriprise reports beneficial ownership of 6,287,151 shares, representing 7.1% of Personalis’ outstanding common stock.

Ameriprise reports no sole voting or dispositive power, with all reported voting and dispositive power shared across these holdings. The firm states that the securities were acquired and are held in the ordinary course of business, not for the purpose of changing or influencing control of Personalis, and disclaims beneficial ownership of the shares reported.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

Personalis, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

71535D106

(CUSIP Number)

12/31/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 71535D106

1

Names of Reporting Persons

Ameriprise Financial, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 6,257,285.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 6,287,151.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

6,287,151.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

7.1 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Personalis, Inc.
(b)	Address of issuer's principal executive offices: 6600 Dumbarton Circle, Fremont, CA 94555
Item 2.
(a)	Name of person filing: Ameriprise Financial, Inc. ("AFI")
(b)	Address or principal business office or, if none, residence: 145 Ameriprise Financial Center, Minneapolis, MN 55474
(c)	Citizenship: Delaware
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 71535D106
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: Incorporated by reference to Items (5)-(9) and (11) of the cover page pertaining to the reporting person. AFI disclaims beneficial ownership of any shares reported on this Schedule.
(b)	Percent of class: The information required by Item 4(b) is set forth in Rows (5)-(9) and (11) of the cover page for the Reporting Person hereto and is incorporated herein by reference for the Reporting Person.
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for the Reporting Person hereto and is incorporated herein by reference for the Reporting Person.
	(ii) Shared power to vote or to direct the vote: The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for the Reporting Person hereto and is incorporated herein by reference for the Reporting Person.
	(iii) Sole power to dispose or to direct the disposition of: The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for the Reporting Person hereto and is incorporated herein by reference for the Reporting Person.
	(iv) Shared power to dispose or to direct the disposition of: The information required by Item 4(c) is set forth in Rows (5)-(9) and (11) of the cover page for the Reporting Person hereto and is incorporated herein by reference for the Reporting Person.
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Ameriprise Financial, Inc.

Signature:	/s/ Michael G. Clarke
Name/Title:	Michael G. Clarke, Senior Vice President, North America Head of Operations & Investor Services
Date:	02/17/2026

Comments accompanying signature: Contact Information Charles Chiesa VP Fund Treasurer Global Operations and Investor Services Telephone: 617-385-9593

FAQ

What stake does Ameriprise Financial report in Personalis, Inc. (PSNL)?

Ameriprise Financial reports beneficial ownership of 6,287,151 Personalis common shares, representing 7.1% of the class as of 12/31/2025. This reflects a sizable institutional position but is disclosed as ordinary-course investment activity rather than an effort to influence control.

Does Ameriprise Financial have voting control over its PSNL shares?

Ameriprise reports 0 shares with sole voting power and 6,257,285 shares with shared voting power. It also reports only shared dispositive power, indicating that authority over these Personalis shares is exercised jointly, not by Ameriprise alone.

Why did Ameriprise file a Schedule 13G for Personalis (PSNL)?

The Schedule 13G reflects that Ameriprise crossed the 5% ownership threshold in Personalis common stock. The filing states the shares were acquired and are held in the ordinary course of business, and not with the purpose or effect of changing or influencing control.

Does Ameriprise Financial seek to influence control of Personalis, Inc.?

No. Ameriprise certifies the Personalis shares were acquired and are held in the ordinary course of business, not to change or influence control of the issuer, and not in connection with any transaction having that purpose or effect, aside from limited proxy-nomination activities referenced.

Does Ameriprise Financial claim full beneficial ownership of its PSNL position?

Ameriprise expressly disclaims beneficial ownership of the Personalis shares reported on the Schedule 13G. The filing attributes the numerical ownership figures to Ameriprise for reporting purposes while clarifying that it disclaims beneficial ownership under applicable securities law definitions.

Who signed the Ameriprise Schedule 13G regarding Personalis (PSNL)?

The Schedule 13G was signed by Michael G. Clarke, Senior Vice President, North America Head of Operations & Investor Services, on 02/17/2026. The signature certifies that the information in the statement is true, complete, and correct to the best of his knowledge and belief.