STOCK TITAN

Rhythm Pharmaceuticals (RYTM) EVP exercises 56,601 options and sells 75,834 shares

(Very High)
(Very Negative)
Form Type
4

Rhea-AI Filing Summary

Rhythm Pharmaceuticals EVP Jennifer Kayden Lee reported multiple transactions in company equity on August 13, 2026. She exercised stock options covering 56,601 shares of common stock at exercise prices of $24.29 and $6.80 per share, receiving the corresponding common shares. She then sold 75,834 shares of common stock at a price of $117.3818 per share. All exercises and sales were effected pursuant to a Rule 10b5-1 trading plan adopted on May 14, 2026.

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Insights

Analyzing...

Insider Lee Jennifer Kayden
Role EVP, Head of North America
Sold 75,834 shs ($8.90M)
Approx. gross sale proceeds $8.90M
Approx. exercise cost $997K
Type Security Shares Price Value
Exercise Stock Options (Right to Buy) F1, F2 35,000 $0.00 $0.00
Exercise Stock Options (Right to Buy) F1, F3 21,601 $0.00 $0.00
Exercise Common Stock F1 35,000 $24.29 $850K
Exercise Common Stock F1 21,601 $6.80 $147K
Sale Common Stock F1 75,834 $117.3818 $8.90M
Holdings After Transaction: Stock Options (Right to Buy) — 36,283 shares (Direct); Common Stock — 0 shares (Direct)
Footnotes (3)
  1. F1. The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.
  2. F2. The stock options were granted on November 9, 2020. 25% of the shares subject to the option vested and become exercisable on November 9, 2021 and the remaining 75% of the shares subject to the option vested and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.
  3. F3. The stock options were granted on February 9, 2022. The options vested and became exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.
Shares sold 75,834 shares Common stock sale on August 13, 2026
Sale price per share $117.3818 Price for 75,834 common shares sold
Options exercised 56,601 shares Total underlying common shares from option exercises
Option exercise price 1 $24.29 Exercise price for 35,000 options granted November 9, 2020
Option exercise price 2 $6.80 Exercise price for 21,601 options granted February 9, 2022
10b5-1 plan adoption date May 14, 2026 Date reporting person adopted Rule 10b5-1 trading plan
Option expiration 1 November 9, 2030 Expiration date for 2020 stock option grant
Option expiration 2 February 8, 2032 Expiration date for 2022 stock option grant
Rule 10b5-1 trading plan regulatory
"The exercises and sales ... were effected pursuant to a Rule 10b5-1 trading plan"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
Stock Options (Right to Buy) financial
"security_title: Stock Options (Right to Buy) with underlying common stock"
Exercise or conversion of derivative security financial
"transaction_code_description: Exercise or conversion of derivative security"
Common Stock financial
"underlying_security_title: Common Stock for exercised options"
Common stock represents ownership shares in a company, giving investors a stake in its success and a say in important decisions through voting rights. It is the most common type of stock traded on markets and can provide income through dividends, as well as potential for value growth. For investors, holding common stock means sharing in the company’s profits and risks.
expiration date financial
"expiration_date: 2030-11-09 and 2032-02-08 for option grants"
The expiration date is the deadline after which a financial contract, such as an option or a futures agreement, is no longer valid or can be exercised. It matters to investors because it determines the timeframe during which they can take action or benefit from the contract, similar to how a coupon or a food item has a limited period of usefulness. Once the expiration date passes, the contract loses its value or ability to be used.

FAQ

What did Rhythm Pharmaceuticals (RYTM) executive Jennifer Kayden Lee report in this Form 4?

Jennifer Kayden Lee reported option exercises for 56,601 shares and the sale of 75,834 common shares of Rhythm Pharmaceuticals stock, with all transactions executed under a previously adopted Rule 10b5-1 trading plan.

How many Rhythm Pharmaceuticals (RYTM) shares did the EVP sell and at what price?

The EVP sold 75,834 shares of Rhythm Pharmaceuticals common stock at a price of $117.3818 per share. The sale occurred on August 13, 2026, and was carried out under a Rule 10b5-1 trading plan.

How many Rhythm Pharmaceuticals (RYTM) options did the EVP exercise and at which strike prices?

She exercised stock options covering 56,601 shares of Rhythm Pharmaceuticals common stock, with exercise prices of $24.29 and $6.80 per share, converting these options into common stock before the reported sale transaction.

Were the reported Rhythm Pharmaceuticals (RYTM) transactions made under a Rule 10b5-1 plan?

Yes, the filing states that all exercises and sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 14, 2026, indicating a pre-arranged trading program.

What is the role of the reporting person at Rhythm Pharmaceuticals (RYTM)?

The reporting person, Jennifer Kayden Lee, serves as EVP, Head of North America at Rhythm Pharmaceuticals. The reported transactions involve her directly held options and common stock in the company.

What are the vesting details of the Rhythm Pharmaceuticals (RYTM) options exercised?

One option grant from November 9, 2020 vested 25% on November 9, 2021, with the remainder vesting quarterly thereafter; another grant from February 9, 2022 vested in 16 equal quarterly installments after grant.

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Learn about SEC filing dates
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Lee Jennifer Kayden

(Last)(First)(Middle)
C/O RHYTHM PHARMACEUTICALS, INC.
222 BERKELEY STREET, 12TH FLOOR

(Street)
BOSTON MASSACHUSETTS 02116

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
RHYTHM PHARMACEUTICALS, INC. [ RYTM ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
EVP, Head of North America
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/13/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/13/2026M(1)35,000A$24.2954,233D
Common Stock08/13/2026M(1)21,601A$6.875,834D
Common Stock08/13/2026S(1)75,834D$117.38180D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Options (Right to Buy)$24.2908/13/2026M(1)35,000 (2)11/09/2030Common Stock35,000$036,283D
Stock Options (Right to Buy)$6.808/13/2026M(1)21,601 (3)02/08/2032Common Stock21,601$00D
Explanation of Responses:
1. The exercises and sales reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 14, 2026.
2. The stock options were granted on November 9, 2020. 25% of the shares subject to the option vested and become exercisable on November 9, 2021 and the remaining 75% of the shares subject to the option vested and become exercisable in 12 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer thereafter.
3. The stock options were granted on February 9, 2022. The options vested and became exercisable in 16 substantially equal installments upon the Reporting Person's completion of each three full months of successive service to the Issuer following the grant date.
/s/ Stephen Vander Stoep, attorney-in-fact for Jennifer Kayden Lee08/14/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)