STOCK TITAN

Sol-Gel Technologies (NASDAQ: SLGL) holder adds 1,695 shares

Filing Impact
(Moderate)
Filing Sentiment
(Positive)
Form Type
4

Rhea-AI Filing Summary

Opaleye Management Inc., a ten percent owner of Sol-Gel Technologies Ltd., reported net insider buying. Through Opaleye, L.P., it purchased 775 ordinary shares on July 13 and 920 shares on July 14, 2026, in open‑market transactions at weighted‑average prices of $73.89 and $73.43 per share, executed in multiple trades within disclosed ranges of $73.34–$73.50 and $73.75–$73.95. Following these trades, Opaleye, L.P. holds 493,936 shares, and a separately managed account overseen by Opaleye Management holds 15,000 shares. Opaleye Management disclaims beneficial ownership beyond its pecuniary interest.

Positive

  • None.

Negative

  • None.
Insider Opaleye Management Inc.
Role 10% Owner
Bought 1,695 shs ($125K)
Type Security Shares Price Value
Purchase Ordinary Shares, par value NIS 1.00 per share 920 $73.4304 $68K
Purchase Ordinary Shares, par value NIS 1.00 per share 775 $73.8873 $57K
holding Ordinary Shares, par value NIS 1.00 per share -- -- --
Holdings After Transaction: Ordinary Shares, par value NIS 1.00 per share — 493,936 shares (Indirect, By Opaleye, L.P.)
Footnotes (1)
  1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $73.75-$73.95 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $73.34-$73.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Total shares purchased 1,695 shares Ordinary shares bought in open-market transactions on July 13–14, 2026
July 13, 2026 purchase price $73.8873 per share Weighted-average price for 775 ordinary shares bought on July 13, 2026
July 14, 2026 purchase price $73.4304 per share Weighted-average price for 920 ordinary shares bought on July 14, 2026
Fund holdings after trades 493,936 shares Ordinary shares held indirectly via Opaleye, L.P. following July 14, 2026 purchase
Managed account holdings 15,000 shares Ordinary shares held indirectly in a separately managed account as of July 13, 2026
beneficially own regulatory
"may be deemed to beneficially own the securities owned directly by the Fund"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
separately managed account financial
"Securities owned by a separately managed account (the "Managed Account")."
A separately managed account (SMA) is a personalized investment portfolio owned by a single investor and run by a professional manager who buys and sells securities on that investor’s behalf. It matters to investors because an SMA offers tailored asset selection, tax handling, and transparency—like hiring a personal chef who prepares meals to your dietary needs rather than sharing a set menu—so you can align holdings with your goals and see exactly what you own.
weighted average price financial
"The price reported in column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
pecuniary interest regulatory
"disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest"
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FAQ

What insider buying did Opaleye Management report for Sol-Gel Technologies (SLGL)?

Opaleye Management reported buying a total of 1,695 ordinary shares of Sol-Gel Technologies in open-market transactions, split between 775 shares on July 13 and 920 shares on July 14, 2026, at weighted-average prices in the low $70s.

At what prices were the recent SLGL shares purchased by Opaleye Management?

The reported purchases were made at weighted-average prices of $73.8873 per share for 775 shares and $73.4304 per share for 920 shares. Footnotes note these were executed in multiple trades within ranges of $73.34–$73.50 and $73.75–$73.95.

How many Sol-Gel Technologies (SLGL) shares does Opaleye, L.P. hold after these trades?

After the July 14, 2026 purchase, Opaleye, L.P. is reported as holding 493,936 Sol-Gel Technologies ordinary shares. These shares are owned directly by the fund, with Opaleye Management potentially deemed to beneficially own them as investment manager.

What additional SLGL holdings are reported in Opaleye Management’s managed account?

A separately managed account overseen by Opaleye Management is reported as holding 15,000 Sol-Gel Technologies ordinary shares. Opaleye Management, as portfolio manager of this managed account, may be deemed to beneficially own the securities held in that account.

Are Opaleye Management’s SLGL transactions direct or indirect holdings?

All reported Sol-Gel Technologies positions are indirect holdings. Shares are held by Opaleye, L.P. and a separately managed account. Opaleye Management disclaims beneficial ownership of these shares except to the extent of its pecuniary interest in the positions.

Were the SLGL purchases by Opaleye Management open-market transactions?

Yes. The two reportable trades for Sol-Gel Technologies are coded as “P”, described as open-market or private purchase transactions. Footnotes clarify the reported prices are weighted averages for multiple executions within specified price ranges.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Opaleye Management Inc.

(Last)(First)(Middle)
ONE BOSTON PLACE, 26TH FLOOR

(Street)
BOSTON MASSACHUSETTS 02108

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Sol-Gel Technologies Ltd. [ SLGL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
07/13/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares, par value NIS 1.00 per share07/13/2026P775A$73.8873(3)493,016IBy Opaleye, L.P.(1)(5)
Ordinary Shares, par value NIS 1.00 per share07/14/2026P920A$73.4304(4)493,936IBy Opaleye, L.P.(1)(5)
Ordinary Shares, par value NIS 1.00 per share15,000IBy Managed Account(2)(5)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
3. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $73.75-$73.95 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
4. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $73.34-$73.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
5. Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Opaleye Management, Inc., By: /s/ James Silverman, President07/15/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)