Welcome to our dedicated page for Trevi Therapeutics SEC filings (Ticker: TRVI), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
Trevi Therapeutics, Inc. filings document a Nasdaq-listed clinical-stage biopharmaceutical company developing Haduvio, oral nalbuphine ER, for chronic cough indications including IPF-related chronic cough, non-IPF interstitial lung disease, and refractory chronic cough. Its 8-K filings report financial results, clinical development updates, FDA meeting disclosures, and material events related to the Haduvio program.
The company’s SEC record also includes registration and offering materials for common stock financings, underwriting agreements, and proxy disclosures covering director elections, executive compensation, governance matters, and equity-based compensation. These filings describe Trevi’s capital structure, development-stage operating profile, and public-company governance.
Cassella James V reported acquisition or exercise transactions in this Form 4 filing.
Trevi Therapeutics, Inc. reported that Chief Development Officer James V. Cassella received a grant of stock options covering 215,000 shares of common stock on February 19, 2026. The options were granted at a price of $0.0000 per share as a compensation award.
The 215,000 underlying shares are scheduled to vest in equal monthly installments through February 19, 2030, and vesting depends on Cassella’s continued service with the company. Following this award, he holds stock options for 215,000 shares directly.
Trevi Therapeutics, Inc. reported that company officer Christopher Galletta received a grant of stock options covering 35,000 shares of common stock. The award was made on February 19, 2026 as a compensation-related acquisition, not an open-market purchase.
The 35,000 underlying shares are scheduled to vest in equal monthly installments through February 19, 2030, conditioned on Galletta’s continued service with the company. This filing simply records the new equity award and Galletta’s resulting direct ownership of these options.
Trevi Therapeutics, Inc. reported that its Chief Scientific Officer, Thomas Sciascia, received a grant of stock options covering 85,000 shares of common stock. The options were awarded at an exercise price of $0.00 per share, reflecting a compensatory grant rather than an open-market purchase. According to the filing, these 85,000 underlying shares are scheduled to vest in equal monthly installments through February 19, 2030, and the vesting is conditioned on his continued service with the company.
Trevi Therapeutics, Inc. reported that President and CEO Jennifer L. Good received a grant of stock options covering 675,000 shares of common stock. The award was granted on February 19, 2026 at no cost on grant and represents a compensation-related acquisition, not an open-market purchase.
The 675,000 underlying shares are scheduled to vest in equal monthly installments through February 19, 2030, so long as she continues her service with the company. This structure ties the potential ownership benefit to her ongoing tenure over the multi-year vesting period.
Simon Farrell reported acquisition or exercise transactions in this Form 4 filing.
Trevi Therapeutics Chief Commercial Officer Simon Farrell received a grant of stock options covering 160,000 shares of common stock. The award was made on February 19, 2026 as an equity incentive.
The 160,000 underlying shares are scheduled to vest in equal monthly installments through February 19, 2030, conditioned on Farrell’s continued service with the company.
Rubric Capital Management LP and David Rosen report beneficial ownership of 3,766,749 shares of Trevi Therapeutics, Inc. common stock, equal to 2.94% of the outstanding shares based on 128,230,134 shares as of October 31, 2025. They share voting and dispositive power over all reported shares and indicate that the position is held in the ordinary course of business. They state the holdings were not acquired and are not held to change or influence control of Trevi Therapeutics.
Trevi Therapeutics, Inc. received an updated Schedule 13D/A from New Enterprise Associates–affiliated funds and managers, correcting earlier disclosures after exercises of certain NEA 16 warrants and acquisition of the underlying common shares before Amendment No. 7.
As of February 13, 2026, the NEA funds report beneficial ownership of a combined 15,074,080 shares of Trevi common stock, representing 11.6% of the class, based on 130,081,986 shares including NEA 16 warrants. This includes 12,273,280 shares held by NEA 16 and 948,948 shares held by NEA 18 Venture Growth Equity, plus 1,851,852 shares underlying NEA 16 warrants. Individual manager Forest Baskett is deemed to beneficially own 14,125,132 shares, or 10.9%. The filing states the firm shares were acquired for investment purposes and notes no specific current plans for corporate changes, though the funds may buy or sell additional shares over time.
Trevi Therapeutics reported that investment manager FMR LLC, together with Abigail P. Johnson, has filed a Schedule 13G showing beneficial ownership of 6,500,009.33 shares of Trevi common stock, representing 5.1% of the class as of 12/31/2025.
FMR LLC has sole voting power over 6,485,775 shares and sole dispositive power over the full 6,500,009.33 shares, with no shared voting or dispositive power. The securities were acquired and are held in the ordinary course of business, and not with the purpose or effect of changing or influencing control of Trevi.
The Vanguard Group has filed a Schedule 13G reporting beneficial ownership of 6,434,655 shares of Trevi Therapeutics common stock, representing 5.01% of the class. Vanguard reports shared voting power over 833,386 shares and shared dispositive power over all 6,434,655 shares.
The holdings are described as being acquired and held in the ordinary course of business, not to change or influence control of Trevi. Vanguard notes an internal realignment effective January 12, 2026, after which certain subsidiaries are expected to report beneficial ownership on a disaggregated basis.
Trevi Therapeutics reported that its Chief Financial Officer, David C. Hastings, received a grant of stock options on January 8, 2026. The award covers 375,000 stock options to purchase common stock at an exercise price of $11.21 per share. According to the vesting schedule, 25% of the underlying 375,000 shares vest on January 8, 2027, with the remaining 75% vesting in equal monthly installments through January 8, 2030. After this grant, Hastings beneficially owns 375,000 derivative securities directly in the form of these options.