Trevi Therapeutics, Inc. filings document a Nasdaq-listed clinical-stage biopharmaceutical company developing Haduvio, oral nalbuphine ER, for chronic cough indications including IPF-related chronic cough, non-IPF interstitial lung disease, and refractory chronic cough. Its 8-K filings report financial results, clinical development updates, FDA meeting disclosures, and material events related to the Haduvio program.
The company’s SEC record also includes registration and offering materials for common stock financings, underwriting agreements, and proxy disclosures covering director elections, executive compensation, governance matters, and equity-based compensation. These filings describe Trevi’s capital structure, development-stage operating profile, and public-company governance.
Rubric Capital Management LP and David Rosen report beneficial ownership of 3,766,749 shares of Trevi Therapeutics, Inc. common stock, equal to 2.94% of the outstanding shares based on 128,230,134 shares as of October 31, 2025. They share voting and dispositive power over all reported shares and indicate that the position is held in the ordinary course of business. They state the holdings were not acquired and are not held to change or influence control of Trevi Therapeutics.
Trevi Therapeutics, Inc. received an updated Schedule 13D/A from New Enterprise Associates–affiliated funds and managers, correcting earlier disclosures after exercises of certain NEA 16 warrants and acquisition of the underlying common shares before Amendment No. 7.
As of February 13, 2026, the NEA funds report beneficial ownership of a combined 15,074,080 shares of Trevi common stock, representing 11.6% of the class, based on 130,081,986 shares including NEA 16 warrants. This includes 12,273,280 shares held by NEA 16 and 948,948 shares held by NEA 18 Venture Growth Equity, plus 1,851,852 shares underlying NEA 16 warrants. Individual manager Forest Baskett is deemed to beneficially own 14,125,132 shares, or 10.9%. The filing states the firm shares were acquired for investment purposes and notes no specific current plans for corporate changes, though the funds may buy or sell additional shares over time.
Trevi Therapeutics reported that investment manager FMR LLC, together with Abigail P. Johnson, has filed a Schedule 13G showing beneficial ownership of 6,500,009.33 shares of Trevi common stock, representing 5.1% of the class as of 12/31/2025.
FMR LLC has sole voting power over 6,485,775 shares and sole dispositive power over the full 6,500,009.33 shares, with no shared voting or dispositive power. The securities were acquired and are held in the ordinary course of business, and not with the purpose or effect of changing or influencing control of Trevi.
The Vanguard Group has filed a Schedule 13G reporting beneficial ownership of 6,434,655 shares of Trevi Therapeutics common stock, representing 5.01% of the class. Vanguard reports shared voting power over 833,386 shares and shared dispositive power over all 6,434,655 shares.
The holdings are described as being acquired and held in the ordinary course of business, not to change or influence control of Trevi. Vanguard notes an internal realignment effective January 12, 2026, after which certain subsidiaries are expected to report beneficial ownership on a disaggregated basis.
Trevi Therapeutics reported that its Chief Financial Officer, David C. Hastings, received a grant of stock options on January 8, 2026. The award covers 375,000 stock options to purchase common stock at an exercise price of $11.21 per share. According to the vesting schedule, 25% of the underlying 375,000 shares vest on January 8, 2027, with the remaining 75% vesting in equal monthly installments through January 8, 2030. After this grant, Hastings beneficially owns 375,000 derivative securities directly in the form of these options.
Trevi Therapeutics, Inc. executive David C. Hastings, the company’s Chief Financial Officer, filed an initial Form 3 ownership report as of 01/08/2026.
The filing indicates that he has no securities beneficially owned in Trevi Therapeutics, with both the non-derivative and derivative securities tables showing no holdings. A power of attorney (Exhibit 24.1) authorizes attorney-in-fact Christopher Galletta to sign the form on his behalf.
Trevi Therapeutics (TRVI) filed its Q3 2025 10‑Q, reporting a net loss of $11.8 million (basic and diluted $(0.08) per share) versus $13.2 million (($(0.13)) a year ago. Operating expenses were $13.9 million, comprised of $10.1 million in R&D and $3.8 million in G&A. Interest income contributed $2.1 million in the quarter.
For the nine months, net loss was $34.4 million. The balance sheet strengthened: cash and cash equivalents $56.9 million and marketable securities $138.1 million at September 30, 2025, supporting total current assets $198.3 million. Stockholders’ equity was $189.8 million and total liabilities were $9.6 million.
Year‑to‑date financing cash inflows were $120.7 million, including $108.2 million from a June 2025 underwritten offering and $10.8 million from warrant exercises. Shares outstanding were 128,215,113 at September 30, 2025; 128,230,134 were outstanding as of October 31, 2025.
Trevi Therapeutics (TRVI) announced financial results for the quarter ended September 30, 2025, and furnished a detailed press release as Exhibit 99.1. The disclosure under Item 2.02 is furnished, not filed, and is not subject to Section 18 liability or incorporated by reference unless specifically referenced.
Trevi Therapeutics, Inc. (TRVI) submitted a Form 144 notice indicating a proposed sale of 108,650 shares of common stock through Stifel Nicolaus & Company Inc with an aggregate market value of $1,032,175.00. The proposed approximate sale date is 10/07/2025, and the shares trade on Nasdaq. The filing shows these shares were acquired by an option exercise on 02/26/2023, originally representing 312,855 shares from that exercise.
The filer also reported equity sales totaling 341,505 shares in the prior three months, generating gross proceeds of approximately $2,863,024.00 across multiple dates from 08/27/2025 to 10/06/2025. The shares outstanding figure listed is 121,776,855, making the proposed sale roughly 0.09% of outstanding stock. The notice includes the standard representation that the seller is not aware of undisclosed material adverse information.
Trevi Therapeutics, Inc. submitted a Form 144 disclosing a proposed sale of 40,000 shares of common stock through Stifel Nicolaus & Company with an aggregate market value of $386,716, expected on 10/03/2025. The filing reports 121,776,855 shares outstanding. The securities being sold were originally acquired via an option exercise on 02/26/2023 totaling 312,855 shares with a reported payment date of 02/16/2023. The filer also disclosed recent open-market sales by Lisa Delfini totaling 312,855 shares during Aug–Sep 2025, including a 155,000-share sale on 09/09/2025 that generated $1,256,787.