STOCK TITAN

Xenetic Biosciences (NASDAQ: XBIO) Q2 2026 loss $0.9M, cash $6.5M

(Moderate)
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Xenetic Biosciences, Inc. reported financial results for the quarter ended June 30, 2026 and highlighted progress on its proprietary DNase immuno-oncology platform. Royalty revenue for the quarter was approximately $0.7 million, up about 12% from approximately $0.6 million in the prior-year period, contributing to approximately $1.5 million in royalty revenue during the first six months of 2026.

Research and development expenses decreased to approximately $0.6 million, while general and administrative expenses rose to approximately $1.1 million, largely due to higher legal costs tied to an ongoing strategic review process. Net loss for the quarter was approximately $0.9 million. The company ended the second quarter with approximately $6.5 million in cash and cash equivalents, compared to approximately $7.9 million as of December 31, 2025, and continues to advance its DNase platform through preclinical, translational and collaborative research efforts.

Positive

  • None.

Negative

  • None.

Filing Explained

The filing says the Board’s strategic review remains unresolved: it may decide not to pursue a strategic alternative, and no completed transaction or resulting change for common holders is disclosed.

Item 2.02 Results of Operations and Financial Condition Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Royalty revenue Q2 2026 approximately $0.7 million Royalty revenue for the three months ended June 30, 2026; increased about 12% from approximately $0.6 million in the prior-year period
Royalty revenue H1 2026 approximately $1.5 million Royalty revenue received during the first six months of 2026
Research and development expenses Q2 2026 approximately $0.6 million R&D expenses for the three months ended June 30, 2026; decreased about 16% from approximately $0.7 million in the comparable prior-year period
General and administrative expenses Q2 2026 approximately $1.1 million G&A expenses for the three months ended June 30, 2026; increased about 64% from approximately $0.7 million in the comparable quarter of 2025
Net loss Q2 2026 approximately $0.9 million Net loss for the quarter ended June 30, 2026; compared to approximately $0.7 million for the same period in 2025
Cash and cash equivalents June 30, 2026 approximately $6.5 million Cash and cash equivalents at the end of the second quarter of 2026; compared to approximately $7.9 million as of December 31, 2025
neutrophil extracellular traps (NETs) medical
"by targeting neutrophil extracellular traps (NETs), an increasingly recognized driver of tumor"
Neutrophil extracellular traps (NETs) are web-like strands of DNA and proteins expelled by white blood cells to trap and neutralize germs; imagine a sticky spider web that captures invaders. They matter to investors because excessive or persistent NET formation is linked to inflammation, organ damage, and disease progression, making NETs both potential biomarkers and drug targets—so therapies or tests that modify NETs can affect clinical outcomes and commercial value.
CAR T-cell therapy medical
"study evaluating systemic recombinant human DNase I in combination with anti-CD19 CAR T-cell therapy"
Car T-cell therapy is a medical treatment that uses a patient’s own immune cells, modified in a lab to better recognize and attack cancer cells. It is considered a breakthrough because it offers potentially long-lasting effects for certain types of cancer. For investors, its development and approval can signal advances in healthcare innovation and potential growth opportunities in the biotech sector.
translational data medical
"Ongoing generation of translational data designed to support future clinical development"
investigator-initiated exploratory study medical
"approval ... to conduct an investigator-initiated exploratory study evaluating systemic recombinant"
royalty revenue financial
"Received approximately $1.5 million in royalty revenue during the first six months of 2026"
Royalty revenue is money a company earns when it lets others use its intangible assets—such as patents, trademarks, copyrights, or natural resources—and receives payments tied to sales, production, or a fixed fee. Investors watch royalty revenue because it can provide steady, high-margin income with low ongoing costs, much like a landlord collecting rent: dependable cashflow that depends on the licensee’s success and the terms of the agreement.
Royalty revenue approximately $0.7 million increased approximately 12% from approximately $0.6 million in the comparable prior-year period
Research and development expenses approximately $0.6 million decreased approximately 16% from approximately $0.7 million in the comparable prior-year period
General and administrative expenses approximately $1.1 million increased approximately 64% from approximately $0.7 million in the comparable quarter of 2025
Net loss approximately $0.9 million compared to approximately $0.7 million for the same period in 2025
Cash and cash equivalents approximately $6.5 million compared to approximately $7.9 million as of December 31, 2025

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FAQ

What financial results did Xenetic Biosciences (XBIO) report for Q2 2026?

Xenetic Biosciences reported Q2 2026 royalty revenue of about $0.7 million and a net loss of about $0.9 million. Royalty revenue rose roughly 12% year over year, while operating expenses and higher legal costs contributed to the quarterly loss.

How did Xenetic Biosciences (XBIO) royalty revenue change in Q2 2026?

Royalty revenue in Q2 2026 was approximately $0.7 million, an increase of about 12% from approximately $0.6 million in the prior-year quarter. The company generated about $1.5 million in royalty revenue over the first six months of 2026.

What net loss did Xenetic Biosciences (XBIO) record in Q2 2026?

Xenetic Biosciences recorded a Q2 2026 net loss of approximately $0.9 million, compared with approximately $0.7 million in the same period of 2025. The change reflects higher general and administrative expenses, partly offset by increased royalty revenue and lower R&D costs.

What was Xenetic Biosciences (XBIO) cash position at the end of Q2 2026?

Xenetic Biosciences ended the second quarter of 2026 with approximately $6.5 million in cash and cash equivalents, compared to approximately $7.9 million as of December 31, 2025. Recurring royalty revenue provides non-dilutive funding to support its development programs.

What strategic and scientific initiatives did Xenetic Biosciences (XBIO) highlight?

The company emphasized its proprietary DNase platform, including positive preclinical data showing enhanced CAR T-cell activity, an approved investigator-initiated DNase I study with PeriNess Ltd., and ongoing translational research and a strategic review process supported by recurring royalty income.

How is Xenetic Biosciences (XBIO) advancing its DNase platform clinically?

Xenetic is focusing on systemic DNase as an adjunctive cancer therapy, targeting neutrophil extracellular traps (NETs). Collaborations and translational data are intended to support future clinical development, including use with CAR T-cell therapies and in pancreatic carcinoma and advanced solid tumors.
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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

________________________

 

FORM 8-K

________________________

 

CURRENT REPORT

Pursuant to Section 13 or 15(d) of The Securities Exchange Act of 1934

 

Date of Report (Date of earliest event reported): August 7, 2026

________________________

 

Xenetic Biosciences, Inc.

(Exact name of registrant as specified in charter)

 

Nevada   001-37937   45-2952962
(State or other jurisdiction
of incorporation)
  (Commission
File Number)
  (IRS Employer
Identification No.)

 

945 Concord Street  
Framingham, Massachusetts 01701
(Address of principal executive offices) (Zip Code)

 

(781) 778-7720

(Registrant’s telephone number, including area code)

 

Not Applicable

(Former name or former address, if changed since last report)

 

Check the appropriate box below if the Form 8-K is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

   Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

 

    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

 

    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

 

    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

Securities registered pursuant to Section 12(b) of the Act:

 

Title of each class   Trading Symbol(s)   Name of each exchange on which registered
Common Stock, $0.001 par value per share   XBIO   The Nasdaq Stock Market

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).

Emerging growth company

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

 

 

   

 

 

Item 2.02. Results of Operations and Financial Condition.

 

On August 7, 2026, Xenetic Biosciences, Inc. (the “Company”) issued a press release announcing results for the three months ended June 30, 2026.

 

The full text of the press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and hereby incorporated in this Item 2.02 by reference. The information in this Item 2.02, including Exhibit 99.1 attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, except as shall be expressly set forth by specific reference in such filing.

 

FORWARD-LOOKING STATEMENTS

 

This Form 8-K, including the press release, contains forward-looking statements that we intend to be subject to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. All statements contained in this Form 8-K, including the press release, other than statements of historical facts may constitute forward-looking statements within the meaning of the federal securities laws. These statements can be identified by words such as “expects,” “plans,” “projects,” “will,” “may,” “anticipates,” “believes,” “should,” “intends,” “estimates,” and other words of similar meaning. Any forward-looking statements contained herein are based on current expectations, and are subject to a number of risks and uncertainties. Many factors could cause our actual activities, performance, achievements or results to differ materially from the activities and results anticipated in forward-looking statements. These risks and uncertainties include those described in the “Risk Factors” section as detailed from time to time in the Company’s reports filed with the Securities and Exchange Commission (“SEC”), including the Company’s annual report on Form 10-K, periodic quarterly reports on Form 10-Q, current reports on Form 8-K and other documents filed with the SEC. In addition, forward-looking statements may also be adversely affected by general market factors, general economic and business conditions, including potential adverse effects of public health issues and geopolitical events, such as the conflicts in the Ukraine and in the Middle East, on economic activity, competitive product development, product availability, federal and state regulations and legislation, the regulatory process for new product candidates and indications, manufacturing issues that may arise, patent positions, litigation, and shareholder activism, among other factors. The forward-looking statements contained in this Form 8-K, including the press release, speak only as of the date the statements were made, and the Company does not undertake any obligation to update forward-looking statements, except as required by law.

 

Item 9.01. Financial Statements and Exhibits.

 

(d) Exhibits

 

Exhibit No.   Description
     
99.1   Press Release dated August 7, 2026 pertaining to the financial results of the Company for the three months ended June 30, 2026.
104   Cover Page Interactive Data File (embedded within the Inline XBRL document).

 

 

 

 

 

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SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

  XENETIC BIOSCIENCES, INC.
     
  By: /s/ James Parslow                                        
Date: August 7, 2026 Name: James Parslow
  Title: Interim Chief Executive Officer and Chief Financial Officer

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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Exhibit 99.1

 

 

 

Xenetic Biosciences Reports Second Quarter 2026 Financial Results and

Highlights Strengthened Scientific Foundation Supporting Continued

Advancement of Proprietary DNase Platform

 

Expanded collaborative research initiatives reinforce the Company's long-term

DNase development strategy

 


Ongoing generation of translational data designed to support future clinical development and deepen

understanding of DNase I-mediated NET targeting


 

Continued royalty generation provides recurring, non-dilutive funding to support continued investment in core development programs

 

FRAMINGHAM, MA – (August 7, 2026)Xenetic Biosciences, Inc. (NASDAQ: XBIO) (“Xenetic” or the “Company”), a biopharmaceutical company focused on advancing innovative immuno-oncology technologies addressing difficult to treat cancers, today reported financial results for the quarter ended June 30, 2026, and provided a corporate update on continued execution of its long-term strategy to advance its proprietary DNase platform through scientific collaboration and translational research.

 

Recent Highlights

 

·Positive preclinical and translational data presented at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting demonstrating that DNase I significantly enhanced CAR T-cell expansion, persistence, tumor control and survival across preclinical hematologic cancer models
·Announced that collaboration partner, PeriNess Ltd., received approval from the Israeli Ministry of Health and the respective Institutional Review Board to conduct an investigator-initiated exploratory study evaluating systemic recombinant human DNase I in combination with anti-CD19 CAR T-cell therapy in patients with large B-cell lymphoma at Tel Aviv Sourasky Medical Center
·Received approximately $1.5 million in royalty revenue during the first six months of 2026

 

“We continue to generate strong translational data as evidenced by what was presented at ASCO, further supporting the potential of DNase I as a differentiated adjunct therapy designed to improve the efficacy and durability of CAR T-cell therapies," said James Parslow, Interim Chief Executive Officer and Chief Financial Officer of Xenetic. "Throughout the second quarter, we continued expanding the scientific foundation supporting our proprietary DNase technology while prudently allocating capital toward activities designed to both inform future clinical development and advance our ongoing strategic review process. We believe this disciplined approach, combined with continued royalty revenue from our legacy PolyXen technology, positions Xenetic to pursue long-term opportunities that have the potential to create meaningful value for both patients and shareholders."

 

Xenetic is advancing its proprietary DNase platform as a differentiated approach designed to enhance the effectiveness of existing cancer therapies by targeting neutrophil extracellular traps (NETs), an increasingly recognized driver of tumor progression, immune suppression and therapeutic resistance. Through collaborations with leading academic institutions, the Company continues to expand the scientific understanding of NET biology while generating translational evidence intended to inform future clinical development and strengthen the long-term potential of its platform.

 

 

 

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Summary of Financial Results for Second Quarter 2026


Royalty revenue for the three months ended June 30, 2026 increased approximately 12% to approximately $0.7 million, compared to approximately $0.6 million for the comparable prior-year period, primarily due to increased royalty revenue recognized under the Company's sublicense agreement with Takeda Pharmaceuticals Co. Ltd.

 

Research and development expenses for the three months ended June 30, 2026 decreased approximately 16% to approximately $0.6 million, compared to approximately $0.7 million for the comparable prior-year period, primarily due to lower manufacturing development efforts and reduced consulting costs.

 

General and administrative expenses for the three months ended June 30, 2026 increased approximately 64% to approximately $1.1 million, compared to approximately $0.7 million in the comparable quarter of 2025. The increase was primarily attributable to higher legal expenses associated with the Company's strategic review process.

 

Net loss for the quarter ended June 30, 2026 was approximately $0.9 million, compared to approximately $0.7 million for the same period in 2025.

 

The Company ended the second quarter of 2026 with approximately $6.5 million in cash and cash equivalents, compared to approximately $7.9 million as of December 31, 2025.

 

About Xenetic Biosciences

 

Xenetic Biosciences, Inc. is a biopharmaceutical company focused on advancing innovative immuno-oncology technologies addressing difficult to treat cancers. The Company's proprietary DNase technology is designed to improve outcomes of existing treatments, including immunotherapies, by targeting neutrophil extracellular traps (NETs), which are involved in cancer progression. Xenetic is currently focused on advancing its systemic DNase program into the clinic as an adjunctive therapy for pancreatic carcinoma and locally advanced or metastatic solid tumors.


For more information, please visit the Company's website at www.xeneticbio.com and connect on X, LinkedIn, and Facebook.

 

 

 

 

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Forward-Looking Statements

 

This press release contains forward-looking statements that we intend to be subject to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release other than statements of historical facts may constitute forward-looking statements within the meaning of the federal securities laws. These statements can be identified by words such as "expects," "plans," "projects," "will," "may," "anticipates," "believes," "should," "intends," "estimates," "remain," "focus", "confidence in", "potential", "continues", "warrants", and other words of similar meaning, including, but not limited to, all statements regarding royalty revenue generation, our belief regarding positioning Xenetic to pursue long-term opportunities that have the potential to create meaningful value for both patients and shareholders, our focus on advancing DNase into the clinic as an adjunctive therapy for pancreatic carcinoma and locally advanced or metastatic solid tumors, the DNase platform improving outcomes of existing treatments, including immunotherapies, by targeting neutrophil extracellular traps (NETs), which are involved in cancer progression, expanding the scientific understanding of NET biology, our generation of translational data and the potential of DNase I as a differentiated adjunctive therapy designed to improve the efficacy and durability of CAR T-cell therapies. Any forward-looking statements contained herein are based on current expectations and are subject to a number of risks and uncertainties. Many factors could cause our actual activities, performance, achievements, or results to differ materially from the activities and results anticipated in forward-looking statements. Important factors that could cause actual activities, performance, achievements, or results to differ materially from such plans, estimates or expectations include, among others, (1) unexpected costs, charges or expenses resulting from our manufacturing and collaboration agreements; (2) unexpected costs, charges or expenses resulting from the licensing of the DNase platform; (3) uncertainty of the expected financial performance of the Company following the licensing of the DNase platform; (4) failure to realize the anticipated potential of the DNase or PolyXen technologies; (5) the ability of the Company to obtain funding and implement its business strategy; (6) risks and uncertainties as to the outcome and timing of the strategic review process being conducted by the Board and a special independent committee thereof, including the possibility that the Board may decide not to undertake a strategic alternative following the evaluation process, the Company's inability to consummate any proposed strategic alternative resulting from the review due to, among other things, market, regulatory and other factors, the potential for disruption to our business resulting from the review process, and potential adverse effects on the Company's stock price from the announcement, suspension or consummation of the evaluation process and the results thereof, as well as risks and uncertainties related to the potential impacts of consummation of a strategic transaction on the Company's current business operations, anticipated business strategy and product development plans; and (7) other risk factors as detailed from time to time in the Company's reports filed with the SEC, including its annual report on Form 10-K, periodic quarterly reports on Form 10-Q, current reports on Form 8-K and other documents filed with the SEC. The foregoing list of important factors is not exclusive. In addition, forward-looking statements may also be adversely affected by general market factors, general economic and business conditions, including potential adverse effects of public health issues, and geopolitical events, such as the conflicts in Ukraine and in the Middle East, on economic activity, competitive product development, product availability, federal and state regulations and legislation, the regulatory process for new product candidates and indications, manufacturing issues that may arise, patent positions, litigation, and shareholder activism, among other factors. The forward-looking statements contained in this press release speak only as of the date the statements were made, and the Company does not undertake any obligation to update forward-looking statements, except as required by law.

 

Contact:

 

JTC Team, LLC

Jenene Thomas

(908) 824-0775

xbio@jtcir.com

 

 

 

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Filing Exhibits & Attachments

4 documents