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Adverum Biotechnologies, Inc. (ADVM) Financials

ADVM
FY2024 annual
Revenue $1.0M -72.2% YoY
Net Income -$130.9M -7.2% YoY
EPS (Diluted) -$6.62 YoY not available
Free Cash Flow -$92.8M -1.2% YoY
Source SEC Filings (10-K/10-Q) Latest period Q3 FY2025, ended Sep 30, 2025 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q3 FY2025, filed Nov 12, 2025. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the ADVM SEC filings page.

Adverum Biotechnologies, Inc. (ADVM) reported $1.0M in revenue for fiscal year 2024, down 72.2% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 13 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ADVM FY2024

Adverum remains a development-stage biotech where research spending vastly exceeds revenue, while financing supplies the balance sheet’s operating fuel.

In FY2024, operating cash flow and free cash flow nearly matched at -$92.5M and -$92.9M, respectively, revealing a cash shortfall driven mainly by operations rather than reinvestment. Revenue fell from $3.6M in FY2023 to $1.0M while research and development remained $77.0M, showing that reported revenue is not yet funding the development effort.

External financing of $120.0M materially offset the year’s operating and investing cash demands, indicating a funding-dependent cash structure rather than internally generated financing. Total liabilities rose from $88.5M in FY2023 to $109.1M in FY2024, signaling greater reliance on obligations.

With development spending dominating the income statement, R&D was roughly seventy-seven times FY2024 revenue, a structure typical of a business still investing ahead of commercial scale. The liquidity measure equaled 16.3 months of reported outflow, which is a balance-to-past-outflow comparison rather than evidence that losses are self-funded.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 54 / 100
Financial Health Score 54/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2024. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Adverum Biotechnologies, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
40

Adverum Biotechnologies, Inc. held $125.7M in cash, cash equivalents and investments at the end of fiscal year 2024, and its operations used $92.5M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and Adverum Biotechnologies, Inc. scores 40/100 among other emerging companies.

Dilution
88

Adverum Biotechnologies, Inc. had 21M shares outstanding at the end of fiscal year 2024. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and Adverum Biotechnologies, Inc. scores 88/100 among other emerging companies.

R&D Intensity
80

Adverum Biotechnologies, Inc. spent $77.0M on research and development in fiscal year 2024, which was 55.0% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and Adverum Biotechnologies, Inc. scores 80/100 among other emerging companies.

Revenue Progress
1

Adverum Biotechnologies, Inc. reported revenue of $1.0M in fiscal year 2024, against $3.6M in fiscal year 2023. Revenue Progress ranks emerging companies on the three-year path of that line, and Adverum Biotechnologies, Inc. scores 1/100 among other emerging companies.

Burn Trend
53

Adverum Biotechnologies, Inc.'s operations used $92.5M of cash in fiscal year 2024, against $90.9M used in fiscal year 2023. Burn Trend ranks emerging companies on which way that figure has moved over three years, and Adverum Biotechnologies, Inc. scores 53/100 among other emerging companies.

Balance Sheet
62

Adverum Biotechnologies, Inc.'s cash, cash equivalents and investments came to $125.7M at the end of fiscal year 2024, against $109.1M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and Adverum Biotechnologies, Inc. scores 62/100 among other emerging companies.

Altman Z-Score Distress
-9.63

Adverum Biotechnologies, Inc. scores -9.63, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($91.5M) relative to total liabilities ($109.1M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/7

Adverum Biotechnologies, Inc. passes 4 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 2 of 4 profitability signals pass, all 2 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality No Cash Backing
N/A

Adverum Biotechnologies, Inc. reported a net loss of $130.9M while operations used $92.5M of cash. With neither figure positive, the ratio between the two carries no quality signal.

Key Financial Metrics

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Earnings & Revenue

Revenue
$0
YoY-100.0%

Adverum Biotechnologies, Inc. generated $0 in revenue in Q3 2025. This represents a decrease of 100.0% from the same quarter a year earlier.

EBITDA
-$47.6M
YoY-41.8%
QoQ+3.6%

Adverum Biotechnologies, Inc.'s EBITDA was -$47.6M in Q3 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 41.8% from the same quarter a year earlier. Against the prior quarter it is up 3.6%.

Net Income
-$47.7M
YoY-47.3%
QoQ+3.1%

Adverum Biotechnologies, Inc. reported -$47.7M in net income in Q3 2025. This represents a decrease of 47.3% from the same quarter a year earlier. Against the prior quarter it is up 3.1%.

EPS (Diluted)
-$2.03
YoY-31.0%
QoQ+13.2%

Adverum Biotechnologies, Inc. earned -$2.03 per diluted share (EPS) in Q3 2025. This represents a decrease of 31.0% from the same quarter a year earlier. Against the prior quarter it is up 13.2%.

Cash & Balance Sheet

Free Cash Flow
-$28.3M
YoY-32.4%
QoQ+27.3%

Adverum Biotechnologies, Inc. recorded an outflow of $28.3M in free cash flow in Q3 2025, representing a cash shortfall after capex. This represents a decrease of 32.4% from the same quarter a year earlier. Against the prior quarter it is up 27.3%.

Cash & Debt
$26.1M
YoY-71.9%
QoQ-38.6%
5Y CAGR-18.5%
10Y CAGR-18.5%

Adverum Biotechnologies, Inc. held $26.1M in cash as of Q3 2025; long-term debt is not reported for that period.

Shares Outstanding
22M
YoY+6.1%
QoQ+5.2%
5Y CAGR-25.7%
10Y CAGR-1.5%

Adverum Biotechnologies, Inc. had 22M shares outstanding in Q3 2025. This represents an increase of 6.1% from the same quarter a year earlier. Against the prior quarter it is up 5.2%.

Dividends Per Share

Not reported for Q3 2025.

Margins & Returns

None of these metrics is reported for Q3 2025.

Capital Allocation

R&D Spending
$38.9M
YoY+90.4%
QoQ+4.8%

Adverum Biotechnologies, Inc. invested $38.9M in research and development in Q3 2025. This represents an increase of 90.4% from the same quarter a year earlier. Against the prior quarter it is up 4.8%.

Capital Expenditures
$142K
YoY-35.7%
QoQ+18.3%
5Y CAGR-46.0%
10Y CAGR-20.0%

Adverum Biotechnologies, Inc. invested $142K in capex in Q3 2025, funding long-term assets and infrastructure. This represents a decrease of 35.7% from the same quarter a year earlier. Against the prior quarter it is up 18.3%.

Share Buybacks

Not reported for Q3 2025.

ADVM Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ADVM quarterly income statement
MetricQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-QQ3'2410-QQ2'2410-QQ1'2410-QQ4'2310-K
Revenue$0-100.0%N/AN/AN/A$1.0M$0$0-100.0%N/A
R&D Expenses$38.9M+90.4%$37.1M+117.1%$28.7M+86.5%N/A$20.4M-1.5%$17.1M-17.0%$15.4M-26.2%N/A
SG&A Expenses$9.1M-39.3%$12.7M-19.5%$19.5M+41.2%N/A$15.0M+4.7%$15.8M+17.3%$13.8M-11.5%N/A
Operating Income-$48.0M-39.4%-$49.9M-51.5%-$48.2M-65.1%N/A-$34.4M+1.8%-$32.9M+3.5%-$29.2M+11.1%N/A
EBITDA-$47.6M-41.8%-$49.3M-54.4%-$47.5M-68.6%N/A-$33.5M0.0%-$31.9M+1.8%-$28.2M+9.8%N/A
Income TaxN/AN/AN/AN/A$0-100.0%$0-100.0%$0-100.0%N/A
Net Income-$47.7M-47.3%-$49.2M-61.3%-$47.0M-73.2%N/A-$32.4M+3.2%-$30.5M+6.2%-$27.1M+14.3%N/A
EPS (Basic)-$2.03-31.0%-$2.34-60.3%-$2.25-36.4%-$1.98+18.2%-$1.55+53.2%-$1.46+54.8%-$1.65+47.8%-$2.42-633.3%
EPS (Diluted)-$2.03-31.0%-$2.34-60.3%-$2.25-36.4%-$1.98-$1.55-$1.46-$1.65-$2.42
Diluted Shares (Avg)23M+12.5%21M+0.8%21M+27.1%N/A21M21M16MN/A

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

ADVM Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ADVM quarterly balance sheet
MetricQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-QQ3'2410-QQ2'2410-QQ1'2410-QQ4'2310-K
Total Assets$72.4M-65.6%$96.2M-58.1%$137.7M-45.1%$179.8M+15.5%$210.2M+17.1%$229.6M+2.3%$250.5M-0.8%$155.8M-49.5%
Current Assets$28.9M-82.1%$48.4M-73.0%$89.5M-55.1%$131.3M+27.8%$161.1M+29.3%$179.4M+21.9%$199.1M+17.9%$102.8M-46.1%
Cash & Equivalents$26.1M-71.9%$42.4M-66.7%$49.2M-67.1%$60.7M-19.1%$92.9M-11.9%$127.3M+14.5%$149.6M+121.5%$75.0M+9.6%
Short-Term Investments$0-100.0%$2.0M-95.7%$33.9M-22.4%$65.0M+202.1%$60.4M+415.4%$46.5M+53.7%$43.7M-54.8%$21.5M-81.6%
Long-Term Investments$0$0$0$0$0$0$0$0
Total Liabilities$128.1M+25.6%$116.4M+26.2%$111.2M+28.1%$109.1M+23.2%$102.0M+10.4%$92.2M-14.7%$86.9M-20.2%$88.5M-30.2%
Current Liabilities$44.7M+97.9%$31.4M+79.6%$25.1M+51.4%$22.9M+14.6%$22.6M-5.6%$17.5M-56.0%$16.6M-59.5%$20.0M-38.0%
Non-Current Liabilities$83.3M+5.0%$85.0M+13.8%$86.1M+22.6%$86.2M+25.8%$79.4M+16.0%$74.7M+9.1%$70.3M+3.5%$68.6M-27.5%
Total Equity-$55.7M-151.4%-$20.2M-114.7%$26.4M-83.9%$70.7M+5.2%$108.3M+24.1%$137.4M+18.2%$163.7M+13.8%$67.2M-60.5%
Retained Earnings-$1.2B-18.0%-$1.2B-17.1%-$1.1B-15.7%-$1.1B-14.0%-$1.0B-12.6%-$993.7M-13.2%-$963.2M-13.9%-$936.0M-16.6%

Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill, Long-Term Debt.

ADVM Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ADVM quarterly cash flow statement
MetricQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-QQ3'2410-QQ2'2410-QQ1'2410-QQ4'2310-K
Operating Cash Flow-$28.1M-33.1%-$38.8M-95.4%-$42.8M-84.0%-$28.2M-32.5%-$21.1M+11.7%-$19.8M+14.6%-$23.2M-3.7%-$21.3M-15.4%
Depreciation & Amortization$465K-47.8%$535K-44.0%$683K-31.5%$810K-19.7%$890K-41.0%$956K-37.7%$997K-37.4%$1.0M-41.1%
Stock-Based Compensation$2.3M-20.7%$2.4M-38.6%$2.8M-33.3%N/A$3.0M-32.5%$3.9M-11.7%$4.2M-8.7%N/A
Capital Expenditures$142K-35.7%$120K+650.0%$220K+144.4%$61K-68.2%$221K-55.4%$16K-55.6%$90K+5.9%$192K+3.8%
Free Cash Flow-$28.3M-32.4%-$38.9M-95.8%-$43.0M-84.2%-$28.3M-31.6%-$21.3M+12.5%-$19.9M+14.7%-$23.3M-3.7%-$21.5M-15.3%
Investing Cash Flow$1.9M+113.9%$31.9M+1471.0%$31.3M+242.0%-$4.2M+57.6%-$13.3M-173.3%-$2.3M-103.5%-$22.0M-202.3%-$9.9M-542.2%
Financing Cash Flow$9.9M$120K+203.4%$0-100.0%$239K+44.0%$0+100.0%-$116K-1550.0%$119.9M$166K-31.4%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

ADVM Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

ADVM quarterly financial ratios
MetricQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-QQ3'2410-QQ2'2410-QQ1'2410-QQ4'2310-K
Operating MarginN/AN/AN/AN/A-3443.8%N/AN/AN/A
Net MarginN/AN/AN/AN/A-3235.1%N/AN/AN/A
Return on EquityN/AN/A-178.0%-161.4ppN/A-29.9%+8.4pp-22.2%+5.8pp-16.6%+5.4ppN/A
Return on Assets-65.8%-50.4pp-51.1%-37.9pp-34.2%-23.3ppN/A-15.4%+3.2pp-13.3%+1.2pp-10.8%+1.7ppN/A
Current Ratio0.65-6.5x1.54-8.7x3.57-8.4x5.73+0.6x7.12+1.9x10.28+6.6x12.01+7.9x5.14-0.8x
Debt-to-EquityN/AN/A4.21+3.7x1.54+0.2x0.94-0.1x0.67-0.3x0.53-0.2x1.32+0.6x
Asset Turnover0.000.0xN/AN/AN/A0.000.0x0.000.0x0.000.0xN/A
FCF MarginN/AN/AN/AN/A-2134.5%N/AN/AN/A

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Adverum Biotechnologies, Inc. ADVM FY2024 $1.0M -$130.9M N/A $91.5M 54/100
Vivani Medical, Inc. VANI FY2025 $0 $26.6M N/A $110.0M
MiNK Therapeutics, Inc. INKT FY2025 N/A -$12.5M N/A $59.1M
Applied Therapeutics, Inc. APLT FY2024 $455K -$105.6M N/A $14.9M
Immix Biopharma, Inc. IMMX FY2025 N/A -$29.4M N/A $852.7M
Fractyl Health, Inc. GUTS FY2025 $0 -$141.0M N/A $89.9M

Frequently Asked Questions

What is Adverum Biotechnologies, Inc.'s annual revenue?

Adverum Biotechnologies, Inc. (ADVM) reported $1.0M in total revenue for fiscal year 2024. This represents a -72.2% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Adverum Biotechnologies, Inc.'s revenue growing?

Adverum Biotechnologies, Inc. (ADVM) revenue declined by 72.2% year-over-year, from $3.6M to $1.0M in fiscal year 2024.

Is Adverum Biotechnologies, Inc. profitable?

No, Adverum Biotechnologies, Inc. (ADVM) reported a net income of -$130.9M in fiscal year 2024.

Adverum Biotechnologies, Inc. (ADVM) reported diluted earnings per share of -$6.62 for fiscal year 2024. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Adverum Biotechnologies, Inc. (ADVM) had EBITDA of -$135.5M in fiscal year 2024, measuring earnings before interest, taxes, depreciation, and amortization.

Adverum Biotechnologies, Inc. (ADVM) has a return on equity of -185.2% for fiscal year 2024, measuring how efficiently the company generates profit from shareholder equity.

Adverum Biotechnologies, Inc. (ADVM) recorded an outflow of $92.8M in free cash flow during fiscal year 2024. This represents a -1.2% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Adverum Biotechnologies, Inc. (ADVM) recorded an outflow of $92.5M in operating cash flow during fiscal year 2024, representing cash used by core business activities.

Adverum Biotechnologies, Inc. (ADVM) had $179.8M in total assets as of fiscal year 2024, including both current and long-term assets.

Adverum Biotechnologies, Inc. (ADVM) invested $388K in capital expenditures during fiscal year 2024, funding long-term assets and infrastructure.

Adverum Biotechnologies, Inc. (ADVM) invested $77.0M in research and development during fiscal year 2024.

Adverum Biotechnologies, Inc. (ADVM) had 21M shares outstanding as of fiscal year 2024.

Adverum Biotechnologies, Inc. (ADVM) had a current ratio of 5.73 as of fiscal year 2024, which is generally considered healthy.

Adverum Biotechnologies, Inc. (ADVM) had a debt-to-equity ratio of 1.54 as of fiscal year 2024, measuring the company's financial leverage by comparing total debt to shareholder equity.

Adverum Biotechnologies, Inc. (ADVM) had a return on assets of -72.8% for fiscal year 2024, measuring how efficiently the company uses its assets to generate profit.

At the end of fiscal year 2024, Adverum Biotechnologies, Inc. (ADVM) held $125.7M in cash, cash equivalents and investments, and reported an operating cash outflow of $92.5M over that year. Dividing the one by the other, the reported balance equals about 16 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.

Adverum Biotechnologies, Inc. (ADVM) has an Altman Z-Score of -9.63, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Adverum Biotechnologies, Inc. (ADVM) has a Piotroski F-Score of 4 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Adverum Biotechnologies, Inc. (ADVM) reported a net loss of $130.9M while operations used $92.5M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Adverum Biotechnologies, Inc. (ADVM) scores 54 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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